Works matching IS 1756994X AND DT 2021 AND VI 13 AND IP 1


Results: 189
    1

    Functional screen of inflammatory bowel disease genes reveals key epithelial functions.

    Published in:
    Genome Medicine, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13073-021-00996-7
    By:
    • Ntunzwenimana, Jessy Carol;
    • Boucher, Gabrielle;
    • Paquette, Jean;
    • Gosselin, Hugues;
    • Alikashani, Azadeh;
    • Morin, Nicolas;
    • Beauchamp, Claudine;
    • Thauvette, Louise;
    • Rivard, Marie-Ève;
    • Dupuis, Frédérique;
    • Deschênes, Sonia;
    • Foisy, Sylvain;
    • Latour, Frédéric;
    • Lavallée, Geneviève;
    • Daly, Mark J.;
    • Xavier, Ramnik J.;
    • the iGenoMed Consortium;
    • Bitton, Alain;
    • Charron, Guy;
    • Rosiers, Christine Des
    Publication type:
    Article
    2

    Functional screen of inflammatory bowel disease genes reveals key epithelial functions.

    Published in:
    Genome Medicine, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13073-021-00996-7
    By:
    • Ntunzwenimana, Jessy Carol;
    • Boucher, Gabrielle;
    • Paquette, Jean;
    • Gosselin, Hugues;
    • Alikashani, Azadeh;
    • Morin, Nicolas;
    • Beauchamp, Claudine;
    • Thauvette, Louise;
    • Rivard, Marie-Ève;
    • Dupuis, Frédérique;
    • Deschênes, Sonia;
    • Foisy, Sylvain;
    • Latour, Frédéric;
    • Lavallée, Geneviève;
    • Daly, Mark J.;
    • Xavier, Ramnik J.;
    • the iGenoMed Consortium;
    • Bitton, Alain;
    • Charron, Guy;
    • Rosiers, Christine Des
    Publication type:
    Article
    3
    4
    5
    6
    7
    8
    9
    10

    A functionally impaired missense variant identified in French Canadian families implicates FANCI as a candidate ovarian cancer-predisposing gene.

    Published in:
    Genome Medicine, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13073-021-00998-5
    By:
    • Fierheller, Caitlin T.;
    • Guitton-Sert, Laure;
    • Alenezi, Wejdan M.;
    • Revil, Timothée;
    • Oros, Kathleen K.;
    • Gao, Yuandi;
    • Bedard, Karine;
    • Arcand, Suzanna L.;
    • Serruya, Corinne;
    • Behl, Supriya;
    • Meunier, Liliane;
    • Fleury, Hubert;
    • Fewings, Eleanor;
    • Subramanian, Deepak N.;
    • Nadaf, Javad;
    • Bruce, Jeffrey P.;
    • Bell, Rachel;
    • Provencher, Diane;
    • Foulkes, William D.;
    • El Haffaf, Zaki
    Publication type:
    Article
    11

    Germline breast cancer susceptibility genes, tumor characteristics, and survival.

    Published in:
    Genome Medicine, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13073-021-00978-9
    By:
    • Ho, Peh Joo;
    • Khng, Alexis J.;
    • Loh, Hui Wen;
    • Ho, Weang-Kee;
    • Yip, Cheng Har;
    • Mohd-Taib, Nur Aishah;
    • Tan, Veronique Kiak Mien;
    • Tan, Benita Kiat-Tee;
    • Tan, Su-Ming;
    • Tan, Ern Yu;
    • Lim, Swee Ho;
    • Jamaris, Suniza;
    • Sim, Yirong;
    • Wong, Fuh Yong;
    • Ngeow, Joanne;
    • Lim, Elaine Hsuen;
    • Tai, Mei Chee;
    • Wijaya, Eldarina Azfar;
    • Lee, Soo Chin;
    • Chan, Ching Wan
    Publication type:
    Article
    12

    Genomic medicine in the Middle East.

    Published in:
    Genome Medicine, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13073-021-01003-9
    By:
    • Abou Tayoun, Ahmad N.;
    • Fakhro, Khalid A.;
    • Alsheikh-Ali, Alawi;
    • Alkuraya, Fowzan S.
    Publication type:
    Article
    13
    14
    15
    16
    17
    18

    Artificial intelligence enables comprehensive genome interpretation and nomination of candidate diagnoses for rare genetic diseases.

    Published in:
    Genome Medicine, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13073-021-00965-0
    By:
    • De La Vega, Francisco M.;
    • Chowdhury, Shimul;
    • Moore, Barry;
    • Frise, Erwin;
    • McCarthy, Jeanette;
    • Hernandez, Edgar Javier;
    • Wong, Terence;
    • James, Kiely;
    • Guidugli, Lucia;
    • Agrawal, Pankaj B.;
    • Genetti, Casie A.;
    • Brownstein, Catherine A.;
    • Beggs, Alan H.;
    • Löscher, Britt-Sabina;
    • Franke, Andre;
    • Boone, Braden;
    • Levy, Shawn E.;
    • Õunap, Katrin;
    • Pajusalu, Sander;
    • Huentelman, Matt
    Publication type:
    Article
    19
    20
    21
    22

    A small number of early introductions seeded widespread transmission of SARS-CoV-2 in Québec, Canada.

    Published in:
    Genome Medicine, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13073-021-00986-9
    By:
    • Murall, Carmen Lía;
    • Fournier, Eric;
    • Galvez, Jose Hector;
    • N'Guessan, Arnaud;
    • Reiling, Sarah J.;
    • Quirion, Pierre-Olivier;
    • Naderi, Sana;
    • Roy, Anne-Marie;
    • Chen, Shu-Huang;
    • Stretenowich, Paul;
    • Bourgey, Mathieu;
    • Bujold, David;
    • Gregoire, Romain;
    • Lepage, Pierre;
    • St-Cyr, Janick;
    • Willet, Patrick;
    • Dion, Réjean;
    • Charest, Hugues;
    • Lathrop, Mark;
    • Roger, Michel
    Publication type:
    Article
    23

    Identification and drug-induced reversion of molecular signatures of Alzheimer's disease onset and progression in App<sup>NL-G-F</sup>, App<sup>NL-F</sup>, and 3xTg-AD mouse models.

    Published in:
    Genome Medicine, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13073-021-00983-y
    By:
    • Pauls, Eduardo;
    • Bayod, Sergi;
    • Mateo, Lídia;
    • Alcalde, Víctor;
    • Juan-Blanco, Teresa;
    • Sánchez-Soto, Marta;
    • Saido, Takaomi C.;
    • Saito, Takashi;
    • Berrenguer-Llergo, Antoni;
    • Attolini, Camille Stephan-Otto;
    • Gay, Marina;
    • de Oliveira, Eliandre;
    • Duran-Frigola, Miquel;
    • Aloy, Patrick
    Publication type:
    Article
    24
    25
    26
    27
    28

    Integrative epigenomic and high-throughput functional enhancer profiling reveals determinants of enhancer heterogeneity in gastric cancer.

    Published in:
    Genome Medicine, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13073-021-00970-3
    By:
    • Sheng, Taotao;
    • Ho, Shamaine Wei Ting;
    • Ooi, Wen Fong;
    • Xu, Chang;
    • Xing, Manjie;
    • Padmanabhan, Nisha;
    • Huang, Kie Kyon;
    • Ma, Lijia;
    • Ray, Mohana;
    • Guo, Yu Amanda;
    • Sim, Ngak Leng;
    • Anene-Nzelu, Chukwuemeka George;
    • Chang, Mei Mei;
    • Razavi-Mohseni, Milad;
    • Beer, Michael A.;
    • Foo, Roger Sik Yin;
    • Sundar, Raghav;
    • Chan, Yiong Huak;
    • Tan, Angie Lay Keng;
    • Ong, Xuewen
    Publication type:
    Article
    29
    30

    Multi-omics colocalization with genome-wide association studies reveals a context-specific genetic mechanism at a childhood onset asthma risk locus.

    Published in:
    Genome Medicine, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13073-021-00967-y
    By:
    • Soliai, Marcus M.;
    • Kato, Atsushi;
    • Helling, Britney A.;
    • Stanhope, Catherine T.;
    • Norton, James E.;
    • Naughton, Katherine A.;
    • Klinger, Aiko I.;
    • Thompson, Emma E.;
    • Clay, Selene M.;
    • Kim, Soyeon;
    • Celedón, Juan C.;
    • Gern, James E.;
    • Jackson, Daniel J.;
    • Altman, Matthew C.;
    • Kern, Robert C.;
    • Tan, Bruce K.;
    • Schleimer, Robert P.;
    • Nicolae, Dan L.;
    • Pinto, Jayant M.;
    • Ober, Carole
    Publication type:
    Article
    31
    32
    33
    34
    35
    36

    Lethal variants in humans: lessons learned from a large molecular autopsy cohort.

    Published in:
    Genome Medicine, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13073-021-00973-0
    By:
    • Shamseldin, Hanan E.;
    • AlAbdi, Lama;
    • Maddirevula, Sateesh;
    • Alsaif, Hessa S.;
    • Alzahrani, Fatema;
    • Ewida, Nour;
    • Hashem, Mais;
    • Abdulwahab, Firdous;
    • Abuyousef, Omar;
    • Kuwahara, Hiroyuki;
    • Gao, Xin;
    • Molecular Autopsy Consortium;
    • Aldhalaan, Hesham;
    • Alfaifi, Abdullah;
    • Alhashem, Amal;
    • Alhasan, Khalid;
    • Alnemer, Maha;
    • Alsahan, Nada;
    • Alyamani, Suad;
    • Alzaidan, Hamad
    Publication type:
    Article
    37

    Artificial intelligence enables comprehensive genome interpretation and nomination of candidate diagnoses for rare genetic diseases.

    Published in:
    Genome Medicine, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13073-021-00965-0
    By:
    • De La Vega, Francisco M.;
    • Chowdhury, Shimul;
    • Moore, Barry;
    • Frise, Erwin;
    • McCarthy, Jeanette;
    • Hernandez, Edgar Javier;
    • Wong, Terence;
    • James, Kiely;
    • Guidugli, Lucia;
    • Agrawal, Pankaj B.;
    • Genetti, Casie A.;
    • Brownstein, Catherine A.;
    • Beggs, Alan H.;
    • Löscher, Britt-Sabina;
    • Franke, Andre;
    • Boone, Braden;
    • Levy, Shawn E.;
    • Õunap, Katrin;
    • Pajusalu, Sander;
    • Huentelman, Matt
    Publication type:
    Article
    38

    Molecular profiling of advanced malignancies guides first-line N-of-1 treatments in the I-PREDICT treatment-naïve study.

    Published in:
    Genome Medicine, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13073-021-00969-w
    By:
    • Sicklick, Jason K.;
    • Kato, Shumei;
    • Okamura, Ryosuke;
    • Patel, Hitendra;
    • Nikanjam, Mina;
    • Fanta, Paul T.;
    • Hahn, Michael E.;
    • De, Pradip;
    • Williams, Casey;
    • Guido, Jessica;
    • Solomon, Benjamin M.;
    • McKay, Rana R.;
    • Krie, Amy;
    • Boles, Sarah G.;
    • Ross, Jeffrey S.;
    • Lee, J. Jack;
    • Leyland-Jones, Brian;
    • Lippman, Scott M.;
    • Kurzrock, Razelle
    Publication type:
    Article
    39
    40
    41
    42
    43

    Whole-genome sequence-informed MALDI-TOF MS diagnostics reveal importance of Klebsiella oxytoca group in invasive infections: a retrospective clinical study.

    Published in:
    Genome Medicine, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13073-021-00960-5
    By:
    • Cuénod, Aline;
    • Wüthrich, Daniel;
    • Seth-Smith, Helena M. B.;
    • Ott, Chantal;
    • Gehringer, Christian;
    • Foucault, Frédéric;
    • Mouchet, Roxanne;
    • Kassim, Ali;
    • Revathi, Gunturu;
    • Vogt, Deborah R.;
    • von Felten, Stefanie;
    • Bassetti, Stefano;
    • Tschudin-Sutter, Sarah;
    • Hettich, Timm;
    • Schlotterbeck, Götz;
    • Homberger, Christina;
    • Casanova, Carlo;
    • Moran-Gilad, Jacob;
    • Sagi, Orli;
    • Rodríguez-Sánchez, Belén
    Publication type:
    Article
    44
    45
    46
    47
    48

    Ten-year longitudinal molecular epidemiology study of Escherichia coli and Klebsiella species bloodstream infections in Oxfordshire, UK.

    Published in:
    Genome Medicine, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13073-021-00947-2
    By:
    • Lipworth, Samuel;
    • Vihta, Karina-Doris;
    • Chau, Kevin;
    • Barker, Leanne;
    • George, Sophie;
    • Kavanagh, James;
    • Davies, Timothy;
    • Vaughan, Alison;
    • Andersson, Monique;
    • Jeffery, Katie;
    • Oakley, Sarah;
    • Morgan, Marcus;
    • Hopkins, Susan;
    • Peto, Timothy E. A.;
    • Crook, Derrick W.;
    • Walker, Ann Sarah;
    • Stoesser, Nicole
    Publication type:
    Article
    49
    50