Works matching IS 1756994X AND DT 2021 AND VI 13 AND IP 1

Results: 189

Functional screen of inflammatory bowel disease genes reveals key epithelial functions.

Published in:

Genome Medicine, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13073-021-00996-7

By:

Ntunzwenimana, Jessy Carol;
Boucher, Gabrielle;
Paquette, Jean;
Gosselin, Hugues;
Alikashani, Azadeh;
Morin, Nicolas;
Beauchamp, Claudine;
Thauvette, Louise;
Rivard, Marie-Ève;
Dupuis, Frédérique;
Deschênes, Sonia;
Foisy, Sylvain;
Latour, Frédéric;
Lavallée, Geneviève;
Daly, Mark J.;
Xavier, Ramnik J.;
the iGenoMed Consortium;
Bitton, Alain;
Charron, Guy;
Rosiers, Christine Des

Publication type:

Article

Constructing germline research cohorts from the discarded reads of clinical tumor sequences.

Published in:

Genome Medicine, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13073-021-00999-4

By:

Gusev, Alexander;
Groha, Stefan;
Taraszka, Kodi;
Semenov, Yevgeniy R.;
Zaitlen, Noah

Publication type:

Article

The genomic architecture of EBV and infected gastric tissue from precursor lesions to carcinoma.

Published in:

Genome Medicine, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13073-021-00963-2

By:

Chen, Zhang-Hua;
Yan, Shu-Mei;
Chen, Xi-Xi;
Zhang, Qi;
Liu, Shang-Xin;
Liu, Yang;
Luo, Yi-Ling;
Zhang, Chao;
Xu, Miao;
Zhao, Yi-Fan;
Huang, Li-Yun;
Liu, Bin-Liu;
Xia, Tian-Liang;
Xu, Da-Zhi;
Liang, Yao;
Chen, Yong-Ming;
Wang, Wei;
Yuan, Shu-Qiang;
Zhang, Hui-Zhong;
Yun, Jing-Ping

Publication type:

Article

Multiscale heterogeneity in gastric adenocarcinoma evolution is an obstacle to precision medicine.

Published in:

Genome Medicine, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13073-021-00975-y

By:

Röcken, Christoph;
Amallraja, Anu;
Halske, Christine;
Opasic, Luka;
Traulsen, Arne;
Behrens, Hans-Michael;
Krüger, Sandra;
Liu, Anne;
Haag, Jochen;
Egberts, Jan-Hendrik;
Rosenstiel, Philip;
Meißner, Tobias

Publication type:

Article

The genetic case for cardiorespiratory fitness as a clinical vital sign and the routine prescription of physical activity in healthcare.

Published in:

Genome Medicine, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13073-021-00994-9

By:

Hanscombe, Ken B.;
Persyn, Elodie;
Traylor, Matthew;
Glanville, Kylie P.;
Hamer, Mark;
Coleman, Jonathan R. I.;
Lewis, Cathryn M.

Publication type:

Article

Germline HLA-B evolutionary divergence influences the efficacy of immune checkpoint blockade therapy in gastrointestinal cancer.

Published in:

Genome Medicine, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13073-021-00997-6

By:

Lu, Zhihao;
Chen, Huan;
Jiao, Xi;
Wang, Yujiao;
Wu, Lijia;
Sun, Huaibo;
Li, Shuang;
Gong, Jifang;
Li, Jian;
Zou, Jianling;
Yang, Keyan;
Hu, Ying;
Mao, Beibei;
Zhang, Lei;
Zhang, Xiaotian;
Peng, Zhi;
Lu, Ming;
Wang, Zhenghang;
Zhang, Henghui;
Shen, Lin

Publication type:

Article

Drivers of methicillin-resistant Staphylococcus aureus (MRSA) lineage replacement in China.

Published in:

Genome Medicine, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13073-021-00992-x

By:

Chen, Hongbin;
Yin, Yuyao;
van Dorp, Lucy;
Shaw, Liam P.;
Gao, Hua;
Acman, Mislav;
Yuan, Jizhen;
Chen, Fengning;
Sun, Shijun;
Wang, Xiaojuan;
Li, Shuguang;
Zhang, Yawei;
Farrer, Rhys A.;
Wang, Hui;
Balloux, Francois

Publication type:

Article

Patient-focused pathogen genetic counselling—has the time come?

Published in:

Genome Medicine, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13073-021-00993-w

By:

Ferdinand, Angeline S;
Hocking, Jane S;
Denholm, Justin T.;
Howden, Benjamin P.;
Williamson, Deborah A.

Publication type:

Article

Integration of genetic, transcriptomic, and clinical data provides insight into 16p11.2 and 22q11.2 CNV genes.

Published in:

Genome Medicine, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13073-021-00972-1

By:

Vysotskiy, Mikhail;
Zhong, Xue;
Miller-Fleming, Tyne W.;
Zhou, Dan;
Cox, Nancy J.;
Weiss, Lauren A.

Publication type:

Article

Functional pre-therapeutic evaluation by genome editing of variants of uncertain significance of essential tumor suppressor genes.

Published in:

Genome Medicine, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13073-021-00976-x

By:

Billaud, Amandine;
Chevalier, Louise-Marie;
Augereau, Paule;
Frenel, Jean-Sebastien;
Passot, Christophe;
Campone, Mario;
Morel, Alain

Publication type:

Article

Identification and drug-induced reversion of molecular signatures of Alzheimer's disease onset and progression in App<sup>NL-G-F</sup>, App<sup>NL-F</sup>, and 3xTg-AD mouse models.

Published in:

Genome Medicine, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13073-021-00983-y

By:

Pauls, Eduardo;
Bayod, Sergi;
Mateo, Lídia;
Alcalde, Víctor;
Juan-Blanco, Teresa;
Sánchez-Soto, Marta;
Saido, Takaomi C.;
Saito, Takashi;
Berrenguer-Llergo, Antoni;
Attolini, Camille Stephan-Otto;
Gay, Marina;
de Oliveira, Eliandre;
Duran-Frigola, Miquel;
Aloy, Patrick

Publication type:

Article

The vaginal microbiota and innate immunity after local excisional treatment for cervical intraepithelial neoplasia.

Published in:

Genome Medicine, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13073-021-00977-w

By:

Mitra, Anita;
MacIntyre, David A.;
Paraskevaidi, Maria;
Moscicki, Anna-Barbara;
Mahajan, Vishakha;
Smith, Ann;
Lee, Yun S.;
Lyons, Deirdre;
Paraskevaidis, Evangelos;
Marchesi, Julian R.;
Bennett, Phillip R.;
Kyrgiou, Maria

Publication type:

Article

A mixture model for signature discovery from sparse mutation data.

Published in:

Genome Medicine, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13073-021-00988-7

By:

Sason, Itay;
Chen, Yuexi;
Leiserson, Mark D.M.;
Sharan, Roded

Publication type:

Article

A small number of early introductions seeded widespread transmission of SARS-CoV-2 in Québec, Canada.

Published in:

Genome Medicine, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13073-021-00986-9

By:

Murall, Carmen Lía;
Fournier, Eric;
Galvez, Jose Hector;
N'Guessan, Arnaud;
Reiling, Sarah J.;
Quirion, Pierre-Olivier;
Naderi, Sana;
Roy, Anne-Marie;
Chen, Shu-Huang;
Stretenowich, Paul;
Bourgey, Mathieu;
Bujold, David;
Gregoire, Romain;
Lepage, Pierre;
St-Cyr, Janick;
Willet, Patrick;
Dion, Réjean;
Charest, Hugues;
Lathrop, Mark;
Roger, Michel

Publication type:

Article

Novel temporal and spatial patterns of metastatic colonization from breast cancer rapid-autopsy tumor biopsies.

Published in:

Genome Medicine, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13073-021-00989-6

By:

Huang, Xiaomeng;
Qiao, Yi;
Brady, Samuel W.;
Factor, Rachel E.;
Downs-Kelly, Erinn;
Farrell, Andrew;
McQuerry, Jasmine A.;
Shrestha, Gajendra;
Jenkins, David;
Johnson, W. Evan;
Cohen, Adam L.;
Bild, Andrea H.;
Marth, Gabor T.

Publication type:

Article

Artificial intelligence enables comprehensive genome interpretation and nomination of candidate diagnoses for rare genetic diseases.

Published in:

Genome Medicine, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13073-021-00965-0

By:

De La Vega, Francisco M.;
Chowdhury, Shimul;
Moore, Barry;
Frise, Erwin;
McCarthy, Jeanette;
Hernandez, Edgar Javier;
Wong, Terence;
James, Kiely;
Guidugli, Lucia;
Agrawal, Pankaj B.;
Genetti, Casie A.;
Brownstein, Catherine A.;
Beggs, Alan H.;
Löscher, Britt-Sabina;
Franke, Andre;
Boone, Braden;
Levy, Shawn E.;
Õunap, Katrin;
Pajusalu, Sander;
Huentelman, Matt

Publication type:

Article

Integrating thousands of PTEN variant activity and abundance measurements reveals variant subgroups and new dominant negatives in cancers.

Published in:

Genome Medicine, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13073-021-00984-x

By:

Matreyek, Kenneth A.;
Stephany, Jason J.;
Ahler, Ethan;
Fowler, Douglas M.

Publication type:

Article

Correction to: PRMT1-mediated H4R3me2a recruits SMARCA4 to promote colorectal cancer progression by enhancing EGFR signaling.

Published in:

2021

By:

Yao, Bing;
Gui, Tao;
Zeng, Xiangwei;
Deng, Yexuan;
Wang, Zhi;
Wang, Ying;
Yang, Dongjun;
Li, Qixiang;
Xu, Peipei;
Hu, Ruifeng;
Li, Xinyu;
Chen, Bing;
Wang, Jin;
Zen, Ke;
Li, Haitao;
Davis, Melissa J.;
Herold, Marco J.;
Pan, Hua-Feng;
Jiang, Zhi-Wei;
Huang, David C. S.

Publication type:

Correction Notice

A global cancer data integrator reveals principles of synthetic lethality, sex disparity and immunotherapy.

Published in:

Genome Medicine, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13073-021-00987-8

By:

Yogodzinski, Christopher;
Arab, Abolfazl;
Pritchard, Justin R.;
Goodarzi, Hani;
Gilbert, Luke A.

Publication type:

Article

Intra-patient stability of tumor mutational burden from tissue biopsies at different time points in advanced cancers.

Published in:

Genome Medicine, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13073-021-00979-8

By:

Pham, Timothy V.;
Goodman, Aaron M.;
Sivakumar, Smruthy;
Frampton, Garrett;
Kurzrock, Razelle

Publication type:

Article

Deep learning in cancer diagnosis, prognosis and treatment selection.

Published in:

Genome Medicine, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13073-021-00968-x

By:

Tran, Khoa A.;
Kondrashova, Olga;
Bradley, Andrew;
Williams, Elizabeth D.;
Pearson, John V.;
Waddell, Nicola

Publication type:

Article

Targeting CDC7 potentiates ATR-CHK1 signaling inhibition through induction of DNA replication stress in liver cancer.

Published in:

Genome Medicine, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13073-021-00981-0

By:

Guo, Yuchen;
Wang, Jun;
Benedict, Bente;
Yang, Chen;
van Gemert, Frank;
Ma, Xuhui;
Gao, Dongmei;
Wang, Hui;
Zhang, Shu;
Lieftink, Cor;
Beijersbergen, Roderick L.;
te Riele, Hein;
Qiao, Xiaohang;
Gao, Qiang;
Sun, Chong;
Qin, Wenxin;
Bernards, René;
Wang, Cun

Publication type:

Article

Comprehensive multi-omics integration identifies differentially active enhancers during human brain development with clinical relevance.

Published in:

Genome Medicine, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13073-021-00980-1

By:

Yousefi, Soheil;
Deng, Ruizhi;
Lanko, Kristina;
Salsench, Eva Medico;
Nikoncuk, Anita;
van der Linde, Herma C.;
Perenthaler, Elena;
van Ham, Tjakko J.;
Mulugeta, Eskeatnaf;
Barakat, Tahsin Stefan

Publication type:

Article

Combinatorial patterns of gene expression changes contribute to variable expressivity of the developmental delay-associated 16p12.1 deletion.

Published in:

Genome Medicine, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13073-021-00982-z

By:

Jensen, Matthew;
Tyryshkina, Anastasia;
Pizzo, Lucilla;
Smolen, Corrine;
Das, Maitreya;
Huber, Emily;
Krishnan, Arjun;
Girirajan, Santhosh

Publication type:

Article

Comprehensive mapping of binding hot spots of SARS-CoV-2 RBD-specific neutralizing antibodies for tracking immune escape variants.

Published in:

Genome Medicine, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13073-021-00985-w

By:

Yi, Chunyan;
Sun, Xiaoyu;
Lin, Yixiao;
Gu, Chenjian;
Ding, Longfei;
Lu, Xiao;
Yang, Zhuo;
Zhang, Yaguang;
Ma, Liyan;
Gu, Wangpeng;
Qu, Aidong;
Zhou, Xu;
Li, Xiuling;
Xu, Jianqing;
Ling, Zhiyang;
Xie, Youhua;
Lu, Hongzhou;
Sun, Bing

Publication type:

Article

Profiling diverse sequence tandem repeats in colorectal cancer reveals co-occurrence of microsatellite and chromosomal instability involving Chromosome 8.

Published in:

Genome Medicine, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13073-021-00958-z

By:

Shin, GiWon;
Greer, Stephanie U.;
Hopmans, Erik;
Grimes, Susan M.;
Lee, HoJoon;
Zhao, Lan;
Miotke, Laura;
Suarez, Carlos;
Almeda, Alison F.;
Haraldsdottir, Sigurdis;
Ji, Hanlee P.

Publication type:

Article

Lethal variants in humans: lessons learned from a large molecular autopsy cohort.

Published in:

Genome Medicine, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13073-021-00973-0

By:

Shamseldin, Hanan E.;
AlAbdi, Lama;
Maddirevula, Sateesh;
Alsaif, Hessa S.;
Alzahrani, Fatema;
Ewida, Nour;
Hashem, Mais;
Abdulwahab, Firdous;
Abuyousef, Omar;
Kuwahara, Hiroyuki;
Gao, Xin;
Molecular Autopsy Consortium;
Aldhalaan, Hesham;
Alfaifi, Abdullah;
Alhashem, Amal;
Alhasan, Khalid;
Alnemer, Maha;
Alsahan, Nada;
Alyamani, Suad;
Alzaidan, Hamad

Publication type:

Article

Artificial intelligence enables comprehensive genome interpretation and nomination of candidate diagnoses for rare genetic diseases.

Published in:

Genome Medicine, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13073-021-00965-0

By:

De La Vega, Francisco M.;
Chowdhury, Shimul;
Moore, Barry;
Frise, Erwin;
McCarthy, Jeanette;
Hernandez, Edgar Javier;
Wong, Terence;
James, Kiely;
Guidugli, Lucia;
Agrawal, Pankaj B.;
Genetti, Casie A.;
Brownstein, Catherine A.;
Beggs, Alan H.;
Löscher, Britt-Sabina;
Franke, Andre;
Boone, Braden;
Levy, Shawn E.;
Õunap, Katrin;
Pajusalu, Sander;
Huentelman, Matt

Publication type:

Article

Bacteroides vulgatus and Bacteroides dorei predict immune-related adverse events in immune checkpoint blockade treatment of metastatic melanoma.

Published in:

Genome Medicine, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13073-021-00974-z

By:

Usyk, Mykhaylo;
Pandey, Abhishek;
Hayes, Richard B.;
Moran, Una;
Pavlick, Anna;
Osman, Iman;
Weber, Jeffrey S.;
Ahn, Jiyoung

Publication type:

Article

Correction to: Genome-wide sequencing as a first-tier screening test for short tandem repeat expansions.

Published in:

2021

By:

Rajan-Babu, Indhu-Shree;
Peng, Junran J.;
Chiu, Readman;
IMAGINE Study;
Birch, Patricia;
Couse, Madeline;
Guimond, Colleen;
Lehman, Anna;
Mwenifumbo, Jill;
van Karnebeek, Clara;
Friedman, Jan;
CAUSES Study;
Adam, Shelin;
Du Souich, Christele;
Elliott, Alison;
Nelson, Tanya;
Rajan-Babu;
Li, Chenkai;
Mohajeri, Arezoo;
Dolzhenko, Egor

Publication type:

Correction Notice

Integrative epigenomic and high-throughput functional enhancer profiling reveals determinants of enhancer heterogeneity in gastric cancer.

Published in:

Genome Medicine, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13073-021-00970-3

By:

Sheng, Taotao;
Ho, Shamaine Wei Ting;
Ooi, Wen Fong;
Xu, Chang;
Xing, Manjie;
Padmanabhan, Nisha;
Huang, Kie Kyon;
Ma, Lijia;
Ray, Mohana;
Guo, Yu Amanda;
Sim, Ngak Leng;
Anene-Nzelu, Chukwuemeka George;
Chang, Mei Mei;
Razavi-Mohseni, Milad;
Beer, Michael A.;
Foo, Roger Sik Yin;
Sundar, Raghav;
Chan, Yiong Huak;
Tan, Angie Lay Keng;
Ong, Xuewen

Publication type:

Article

Multi-omics colocalization with genome-wide association studies reveals a context-specific genetic mechanism at a childhood onset asthma risk locus.

Published in:

Genome Medicine, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13073-021-00967-y

By:

Soliai, Marcus M.;
Kato, Atsushi;
Helling, Britney A.;
Stanhope, Catherine T.;
Norton, James E.;
Naughton, Katherine A.;
Klinger, Aiko I.;
Thompson, Emma E.;
Clay, Selene M.;
Kim, Soyeon;
Celedón, Juan C.;
Gern, James E.;
Jackson, Daniel J.;
Altman, Matthew C.;
Kern, Robert C.;
Tan, Bruce K.;
Schleimer, Robert P.;
Nicolae, Dan L.;
Pinto, Jayant M.;
Ober, Carole

Publication type:

Article

Genome-wide analyses of multiple obesity-related cytokines and hormones informs biology of cardiometabolic traits.

Published in:

Genome Medicine, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13073-021-00971-2

By:

Meeks, Karlijn A. C.;
Bentley, Amy R.;
Gouveia, Mateus H.;
Chen, Guanjie;
Zhou, Jie;
Lei, Lin;
Adeyemo, Adebowale A.;
Doumatey, Ayo P.;
Rotimi, Charles N.

Publication type:

Article

Molecular profiling of advanced malignancies guides first-line N-of-1 treatments in the I-PREDICT treatment-naïve study.

Published in:

Genome Medicine, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13073-021-00969-w

By:

Sicklick, Jason K.;
Kato, Shumei;
Okamura, Ryosuke;
Patel, Hitendra;
Nikanjam, Mina;
Fanta, Paul T.;
Hahn, Michael E.;
De, Pradip;
Williams, Casey;
Guido, Jessica;
Solomon, Benjamin M.;
McKay, Rana R.;
Krie, Amy;
Boles, Sarah G.;
Ross, Jeffrey S.;
Lee, J. Jack;
Leyland-Jones, Brian;
Lippman, Scott M.;
Kurzrock, Razelle

Publication type:

Article

Whole-genome sequence-informed MALDI-TOF MS diagnostics reveal importance of Klebsiella oxytoca group in invasive infections: a retrospective clinical study.

Published in:

Genome Medicine, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13073-021-00960-5

By:

Cuénod, Aline;
Wüthrich, Daniel;
Seth-Smith, Helena M. B.;
Ott, Chantal;
Gehringer, Christian;
Foucault, Frédéric;
Mouchet, Roxanne;
Kassim, Ali;
Revathi, Gunturu;
Vogt, Deborah R.;
von Felten, Stefanie;
Bassetti, Stefano;
Tschudin-Sutter, Sarah;
Hettich, Timm;
Schlotterbeck, Götz;
Homberger, Christina;
Casanova, Carlo;
Moran-Gilad, Jacob;
Sagi, Orli;
Rodríguez-Sánchez, Belén

Publication type:

Article

Non-cancer-related pathogenic germline variants and expression consequences in ten-thousand cancer genomes.

Published in:

Genome Medicine, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13073-021-00964-1

By:

Wang, Zishan;
Fan, Xiao;
Shen, Yufeng;
Pagadala, Meghana S;
Signer, Rebecca;
Cygan, Kamil J.;
Fairbrother, William G.;
Carter, Hannah;
Chung, Wendy K.;
Huang, Kuan-lin

Publication type:

Article

Gut microbial determinants of clinically important improvement in patients with rheumatoid arthritis.

Published in:

Genome Medicine, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13073-021-00957-0

By:

Gupta, Vinod K.;
Cunningham, Kevin Y.;
Hur, Benjamin;
Bakshi, Utpal;
Huang, Harvey;
Warrington, Kenneth J.;
Taneja, Veena;
Myasoedova, Elena;
Davis III, John M.;
Sung, Jaeyun

Publication type:

Article

Single-cell exome sequencing reveals multiple subclones in metastatic colorectal carcinoma.

Published in:

Genome Medicine, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13073-021-00962-3

By:

Tang, Jie;
Tu, Kailing;
Lu, Keying;
Zhang, Jiaxun;
Luo, Kai;
Jin, Haoxuan;
Wang, Lei;
Yang, Lie;
Xiao, Weiran;
Zhang, Qilin;
Liu, Xiaoling;
Ge, Xin yi;
Li, Guibo;
Zhou, Zongguang;
Xie, Dan

Publication type:

Article

Ten-year longitudinal molecular epidemiology study of Escherichia coli and Klebsiella species bloodstream infections in Oxfordshire, UK.

Published in:

Genome Medicine, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13073-021-00947-2

By:

Lipworth, Samuel;
Vihta, Karina-Doris;
Chau, Kevin;
Barker, Leanne;
George, Sophie;
Kavanagh, James;
Davies, Timothy;
Vaughan, Alison;
Andersson, Monique;
Jeffery, Katie;
Oakley, Sarah;
Morgan, Marcus;
Hopkins, Susan;
Peto, Timothy E. A.;
Crook, Derrick W.;
Walker, Ann Sarah;
Stoesser, Nicole

Publication type:

Article

GenTB: A user-friendly genome-based predictor for tuberculosis resistance powered by machine learning.

Published in:

Genome Medicine, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13073-021-00953-4

By:

Gröschel, Matthias I.;
Owens, Martin;
Freschi, Luca;
Vargas Jr, Roger;
Marin, Maximilian G.;
Phelan, Jody;
Iqbal, Zamin;
Dixit, Avika;
Farhat, Maha R.

Publication type:

Article

Developmental dynamics of voltage-gated sodium channel isoform expression in the human and mouse brain.

Published in:

Genome Medicine, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13073-021-00949-0

By:

Liang, Lindsay;
Fazel Darbandi, Siavash;
Pochareddy, Sirisha;
Gulden, Forrest O.;
Gilson, Michael C.;
Sheppard, Brooke K.;
Sahagun, Atehsa;
An, Joon-Yong;
Werling, Donna M.;
Rubenstein, John L. R.;
Sestan, Nenad;
Bender, Kevin J.;
Sanders, Stephan J.

Publication type:

Article

The expressed mutational landscape of microsatellite stable colorectal cancers.

Published in:

Genome Medicine, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13073-021-00955-2

By:

Sveen, Anita;
Johannessen, Bjarne;
Eilertsen, Ina A.;
Røsok, Bård I.;
Gulla, Marie;
Eide, Peter W.;
Bruun, Jarle;
Kryeziu, Kushtrim;
Meza-Zepeda, Leonardo A.;
Myklebost, Ola;
Bjørnbeth, Bjørn A.;
Skotheim, Rolf I.;
Nesbakken, Arild;
Lothe, Ragnhild A.

Publication type:

Article

Distinct transcriptional programs stratify ovarian cancer cell lines into the five major histological subtypes.

Published in:

Genome Medicine, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13073-021-00952-5

By:

Barnes, Bethany M.;
Nelson, Louisa;
Tighe, Anthony;
Burghel, George J.;
Lin, I-Hsuan;
Desai, Sudha;
McGrail, Joanne C.;
Morgan, Robert D.;
Taylor, Stephen S.

Publication type:

Article

Correction to: Identification of TBX15 as an adipose master trans regulator of abdominal obesity genes.

Published in:

2021

By:

Pan, David Z.;
Miao, Zong;
Comenho, Caroline;
Rajkumar, Sandhya;
Koka, Amogha;
Lee, Seung Hyuk T.;
Alvarez, Marcus;
Kaminska, Dorota;
Ko, Arthur;
Sinsheimer, Janet S.;
Mohlke, Karen L.;
Mancuso, Nicholas;
Muñoz-Hernandez, Linda Liliana;
Herrera-Hernandez, Miguel;
Tusié-Luna, Maria Teresa;
Aguilar-Salinas, Carlos;
Pietiläinen, Kirsi H.;
Pihlajamäki, Jussi;
Laakso, Markku;
Garske, Kristina M.

Publication type:

Correction Notice

A transcriptome-wide association study of Alzheimer's disease using prediction models of relevant tissues identifies novel candidate susceptibility genes.

Published in:

Genome Medicine, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13073-021-00959-y

By:

Sun, Yanfa;
Zhu, Jingjing;
Zhou, Dan;
Canchi, Saranya;
Wu, Chong;
Cox, Nancy J.;
Rissman, Robert A.;
Gamazon, Eric R.;
Wu, Lang

Publication type:

Article

De novo transcriptomic subtyping of colorectal cancer liver metastases in the context of tumor heterogeneity.

Published in:

Genome Medicine, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13073-021-00956-1

By:

Moosavi, Seyed H.;
Eide, Peter W.;
Eilertsen, Ina A.;
Brunsell, Tuva H.;
Berg, Kaja C. G.;
Røsok, Bård I.;
Brudvik, Kristoffer W.;
Bjørnbeth, Bjørn A.;
Guren, Marianne G.;
Nesbakken, Arild;
Lothe, Ragnhild A.;
Sveen, Anita

Publication type:

Article

Human reference gut microbiome catalog including newly assembled genomes from under-represented Asian metagenomes.

Published in:

Genome Medicine, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13073-021-00950-7

By:

Kim, Chan Yeong;
Lee, Muyoung;
Yang, Sunmo;
Kim, Kyungnam;
Yong, Dongeun;
Kim, Hye Ryun;
Lee, Insuk

Publication type:

Article

Whole-genome association analyses of sleep-disordered breathing phenotypes in the NHLBI TOPMed program.

Published in:

Genome Medicine, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13073-021-00917-8

By:

Cade, Brian E.;
Lee, Jiwon;
Sofer, Tamar;
Wang, Heming;
Zhang, Man;
Chen, Han;
Gharib, Sina A.;
Gottlieb, Daniel J.;
Guo, Xiuqing;
Lane, Jacqueline M.;
Liang, Jingjing;
Lin, Xihong;
Mei, Hao;
Patel, Sanjay R.;
Purcell, Shaun M.;
Saxena, Richa;
Shah, Neomi A.;
Evans, Daniel S.;
Hanis, Craig L.;
Hillman, David R.

Publication type:

Article

An epigenetic and transcriptomic signature of immune tolerance in human monocytes through multi-omics integration.

Published in:

Genome Medicine, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13073-021-00948-1

By:

Brands, Xanthe;
Haak, Bastiaan W.;
Klarenbeek, Augustijn M.;
Butler, Joe;
Uhel, Fabrice;
Qin, Wanhai;
Otto, Natasja A.;
Jakobs, Marja E.;
Faber, Daniël R.;
Lutter, René;
Wiersinga, W. Joost;
van der Poll, Tom;
Scicluna, Brendon P.

Publication type:

Article

Transfer learning between preclinical models and human tumors identifies a conserved NK cell activation signature in anti-CTLA-4 responsive tumors.

Published in:

Genome Medicine, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13073-021-00944-5

By:

Davis-Marcisak, Emily F.;
Fitzgerald, Allison A.;
Kessler, Michael D.;
Danilova, Ludmila;
Jaffee, Elizabeth M.;
Zaidi, Neeha;
Weiner, Louis M.;
Fertig, Elana J.

Publication type:

Article