Works matching IS 1756994X AND DT 2015 AND VI 7

Results: 128

Moving pathogen genomics out of the lab and into the clinic: what will it take?

Published in:

Genome Medicine, 2015, v. 7, p. 1, doi. 10.1186/s13073-015-0254-z

By:

Luheshi, Leila M.;
Raza, Sobia;
Peacock, Sharon J.

Publication type:

Article

A 'fit' microbiota to potentiate cancer immunotherapy.

Published in:

Genome Medicine, 2015, v. 7, p. 1, doi. 10.1186/s13073-015-0256-x

By:

Rescigno, Maria

Publication type:

Article

Landscape of gene fusions in epithelial cancers: seq and ye shall find.

Published in:

Genome Medicine, 2015, v. 7, p. 1, doi. 10.1186/s13073-015-0252-1

By:

Kumar-Sinha, Chandan;
Kalyana-Sundaram, Shanker;
Chinnaiyan, Arul M.

Publication type:

Article

Targeted high-throughput sequencing for genetic diagnostics of hemophagocytic lymphohistiocytosis.

Published in:

Genome Medicine, 2015, v. 7, p. 1, doi. 10.1186/s13073-015-0244-1

By:

Tesi, Bianca;
Lagerstedt-Robinson, Kristina;
Chiang, Samuel C. C.;
Bdira, Eya Ben;
Abboud, Miguel;
Belen, Burcu;
Devecioglu, Omer;
Fadoo, Zehra;
Yeoh, Allen E. J.;
Erichsen, Hans Christian;
Möttönen, Merja;
Haluk Akar, Himmet;
Hästbacka, Johanna;
Kaya, Zuhre;
Nunes, Susana;
Patiroglu, Turkan;
Sabel, Magnus;
Tugrul Saribeyoglu, Ebru;
Tvedt, Tor Henrik;
Unal, Ekrem

Publication type:

Article

A donor-specific epigenetic classifier for acute graft-versus-host disease severity in hematopoietic stem cell transplantation.

Published in:

Genome Medicine, 2015, v. 7, p. 1, doi. 10.1186/s13073-015-0246-z

By:

Paul, Dirk S.;
Jones, Allison;
Sellar, Rob S.;
Mayor, Neema P.;
Feber, Andrew;
Webster, Amy P.;
Afonso, Neuza;
Sergeant, Ruhena;
Szydlo, Richard M.;
Apperley, Jane F.;
Widschwendter, Martin;
Mackinnon, Stephen;
Marsh, Steven G. E.;
Madrigal, J. Alejandro;
Rakyan, Vardhman K.;
Peggs, Karl S.;
Beck, Stephan

Publication type:

Article

ScanIndel: a hybrid framework for indel detection via gapped alignment, split reads and assembly de novo.

Published in:

Genome Medicine, 2015, v. 7, p. 1, doi. 10.1186/s13073-015-0251-2

By:

Yang, Rendong;
Nelson, Andrew C.;
Henzler, Christine;
Thyagarajan, Bharat;
Silverstein, Kevin A. T.

Publication type:

Article

Metagenomic cross-talk: the regulatory interplay between immunogenomics and the microbiome.

Published in:

Genome Medicine, 2015, v. 7, p. 1, doi. 10.1186/s13073-015-0249-9

By:

Levy, Maayan;
Thaiss, Christoph A.;
Elinav, Eran

Publication type:

Article

High-throughput sequencing insights into T-cell receptor repertoire diversity in aging.

Published in:

2015

By:

Goronzy, Jörg J.;
Qian Qi;
Olshen, Richard A.;
Weyand, Cornelia M.

Publication type:

Opinion

Profiling tissue-resident T cell repertoires by RNA sequencing.

Published in:

Genome Medicine, 2015, v. 7, p. 1, doi. 10.1186/s13073-015-0248-x

By:

Brown, Scott D.;
Raeburn, Lisa A.;
Holt, Robert A.

Publication type:

Article

Longitudinal analysis of the peripheral B cell repertoire reveals unique effects of immunization with a new influenza virus strain.

Published in:

Genome Medicine, 2015, v. 7, p. 1, doi. 10.1186/s13073-015-0239-y

By:

Cortina-Ceballos, Bernardo;
Godoy-Lozano, Elizabeth Ernestina;
Téllez-Sosa, Juan;
Ovilla-Muñoz, Marbella;
Sámano-Sánchez, Hugo;
Aguilar-Salgado, Andrés;
Gómez-Barreto, Rosa Elena;
Valdovinos-Torres, Humberto;
López-Martínez, Irma;
Aparicio-Antonio, Rodrigo;
Rodríguez, Mario H.;
Martínez-Barnetche, Jesús

Publication type:

Article

Annotation of pseudogenic gene segments by massively parallel sequencing of rearranged lymphocyte receptor loci.

Published in:

Genome Medicine, 2015, v. 7, p. 1, doi. 10.1186/s13073-015-0238-z

By:

Dean, Jared;
Emerson, Ryan O.;
Vignali, Marissa;
Sherwood, Anna M.;
Rieder, Mark J.;
Carlson, Christopher S.;
Robins, Harlan S.

Publication type:

Article

Complete re-sequencing of a 2Mb topological domain encompassing the FTO/IRXB genes identifies a novel obesity-associated region upstream of IRX5.

Published in:

Genome Medicine, 2015, v. 7, p. 1, doi. 10.1186/s13073-015-0250-3

By:

Hunt, Lilian E.;
Noyvert, Boris;
Bhaw-Rosun, Leena;
Sesay, Abdul K.;
Paternoster, Lavinia;
Nohr, Ellen A.;
Davey Smith, George;
Tommerup, Niels;
Sørensen, Thorkild I. A.;
Elgar, Greg

Publication type:

Article

Clinical metagenomic identification of Balamuthia mandrillaris encephalitis and assembly of the draft genome: the continuing case for reference genome sequencing.

Published in:

Genome Medicine, 2015, v. 7, p. 1, doi. 10.1186/s13073-015-0235-2

By:

Greninger, Alexander L.;
Messacar, Kevin;
Dunnebacke, Thelma;
Naccache, Samia N.;
Federman, Scot;
Bouquet, Jerome;
Mirsky, David;
Nomura, Yosuke;
Yagi, Shigeo;
Glaser, Carol;
Vollmer, Michael;
Press, Craig A.;
Klenschmidt-DeMasters, Bette K.;
Dominguez, Samuel R.;
Chiu, Charles Y.

Publication type:

Article

Practical guidelines for B-cell receptor repertoire sequencing analysis.

Published in:

Genome Medicine, 2015, v. 7, p. 1, doi. 10.1186/s13073-015-0243-2

By:

Yaari, Gur;
Kleinstein, Steven H.

Publication type:

Article

TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression.

Published in:

Genome Medicine, 2015, v. 7, p. 1, doi. 10.1186/s13073-015-0240-5

By:

Scholtalbers, Jelle;
Boegel, Sebastian;
Bukur, Thomas;
Byl, Marius;
Goerges, Sebastian;
Sorn, Patrick;
Loewer, Martin;
Sahin, Ugur;
Castle, John C.

Publication type:

Article

Transcriptome sequencing reveals thousands of novel long non-coding RNAs in B cell lymphoma.

Published in:

Genome Medicine, 2015, v. 7, p. 1, doi. 10.1186/s13073-015-0230-7

By:

Verma, Akanksha;
Yanwen Jiang;
Wei Du;
Fairchild, Lauren;
Melnick, Ari;
Elemento, Olivier

Publication type:

Article

Immunogenomics: a foundation for intelligent immune design.

Published in:

2015

By:

Holt, Robert A.

Publication type:

Editorial

Immunoinformatics and epitope prediction in the age of genomic medicine.

Published in:

Genome Medicine, 2015, v. 7, p. 1, doi. 10.1186/s13073-015-0245-0

By:

Backert, Linus;
Kohlbacher, Oliver

Publication type:

Article

Integrating tumor microenvironment with cancer molecular classifications.

Published in:

Genome Medicine, 2015, v. 7, p. 1, doi. 10.1186/s13073-015-0241-4

By:

Becht, Etienne;
de Reyniès, Aurélien;
Fridman, Wolf H.

Publication type:

Article

The use of systems biology and immunological big data to guide vaccine development.

Published in:

Genome Medicine, 2015, v. 7, p. 1, doi. 10.1186/s13073-015-0236-1

By:

Blohmke, Christoph J.;
O'Connor, Daniel;
Pollard, Andrew J.

Publication type:

Article

Identification of global regulators of T-helper cell lineage specification.

Published in:

Genome Medicine, 2015, v. 7, p. 1, doi. 10.1186/s13073-015-0237-0

By:

Kanduri, Kartiek;
Tripathi, Subhash;
Larjo, Antti;
Mannerström, Henrik;
Ullah, Ubaid;
Lund, Riikka;
Hawkins, R. David;
Bing Ren;
Lähdesmäki, Harri;
Lahesmaa, Riitta

Publication type:

Article

Erratum to: Functional signatures of oral dysbiosis during periodontitis progression revealed by microbial metatranscriptome analysis.

Published in:: 2015
Publication type:: Correction Notice

The Cancer Genome Atlas Clinical Explorer: a web and mobile interface for identifying clinical-genomic driver associations.

Published in:

Genome Medicine, 2015, v. 7, p. 1, doi. 10.1186/s13073-015-0226-3

By:

HoJoon Lee;
Palm, Jennifer;
Grimes, Susan M.;
Hanlee P. Ji

Publication type:

Article

Dynamic tracking of functional gene modules in treated juvenile idiopathic arthritis.

Published in:

Genome Medicine, 2015, v. 7, p. 1, doi. 10.1186/s13073-015-0227-2

By:

Nan Du;
Kaiyu Jiang;
Sawle, Ashley D.;
Frank, Mark Barton;
Wallace, Carol A.;
Aidong Zhang;
Jarvis, James N.

Publication type:

Article

The spliceosome, a potential Achilles heel of MYC-driven tumors.

Published in:

Genome Medicine, 2015, v. 7, p. 1, doi. 10.1186/s13073-015-0234-3

By:

Anczuków, Olga;
Krainer, Adrian R.

Publication type:

Article

The age factor in Alzheimer's disease.

Published in:

Genome Medicine, 2015, v. 7, p. 1, doi. 10.1186/s13073-015-0232-5

By:

Guerreiro, Rita;
Bras, Jose

Publication type:

Article

An integrative systems genetics approach reveals potential causal genes and pathways related to obesity.

Published in:

Genome Medicine, 2015, v. 7, p. 1, doi. 10.1186/s13073-015-0229-0

By:

Kogelman, Lisette J. A.;
Zhernakova, Daria V.;
Westra, Harm-Jan;
Cirera, Susanna;
Fredholm, Merete;
Franke, Lude;
Kadarmideen, Haja N.

Publication type:

Article

A genome-wide approach to link genotype to clinical outcome by utilizing next generation sequencing and gene chip data of 6,697 breast cancer patients.

Published in:

Genome Medicine, 2015, v. 7, p. 1, doi. 10.1186/s13073-015-0228-1

By:

Pongor, Lőrinc;
Kormos, Máté;
Hatzis, Christos;
Pusztai, Lajos;
Szabó, András;
Győrffy, Balázs

Publication type:

Article

Many obesity-associated SNPs strongly associate with DNA methylation changes at proximal promoters and enhancers.

Published in:

Genome Medicine, 2015, v. 7, n. 1, p. 1, doi. 10.1186/s13073-015-0225-4

By:

Voisin, Sarah;
Almén, Markus Sällman;
Zheleznyakova, Galina Y.;
Lundberg, Lina;
Zarei, Sanaz;
Castillo, Sandra;
Eriksson, Fia Ence;
Nilsson, Emil K.;
Blüher, Matthias;
Böttcher, Yvonne;
Kovacs, Peter;
Klovins, Janis;
Rask-Andersen, Mathias;
Schiöth, Helgi B.

Publication type:

Article

Many obesity-associated SNPs strongly associate with DNA methylation changes at proximal promoters and enhancers.

Published in:

Genome Medicine, 2015, v. 7, p. 1, doi. 10.1186/s13073-015-0225-4

By:

Voisin, Sarah;
Sällman Almén, Markus;
Zheleznyakova, Galina Y.;
Lundberg, Lina;
Zarei, Sanaz;
Castillo, Sandra;
Eriksson, Fia Ence;
Nilsson, Emil K.;
Blüher, Matthias;
Böttcher, Yvonne;
Kovacs, Peter;
Klovins, Janis;
Rask-Andersen, Mathias;
Schiöth, Helgi B.

Publication type:

Article

Concept and design of a genome-wide association genotyping array tailored for transplantation-specific studies.

Published in:

Genome Medicine, 2015, v. 7, n. 1, p. 1, doi. 10.1186/s13073-015-0211-x

By:

Yun R. Li;
van Setten, Jessica;
Verma, Shefali S.;
Yontao Lu;
Holmes, Michael V.;
Hui Gao;
Lek, Monkol;
Nair, Nikhil;
Chandrupatla, Hareesh;
Baoli Chang;
Karczewski, Konrad J.;
Wong, Chanel;
Mohebnasab, Maede;
Mukhtar, Eyas;
Phillips, Randy;
Tragante, Vinicius;
Cuiping Hou;
Steel, Laura;
Takesha Lee;
Garifallou, James

Publication type:

Article

Implementing systems medicine within healthcare.

Published in:

Genome Medicine, 2015, v. 7, n. 1, p. 1, doi. 10.1186/s13073-015-0224-5

By:

Kirschner, Marc;
Bauch, Angela;
Agusti, Alvar;
Hilke, Sebastian;
Merk, Sibylle;
Pison, Christophe;
Roldan, Jim;
Seidenath, Bernard;
Wilken, Michael;
Wouters, Emiel F.;
Mewes, Hans-Werner;
Heumann, Klaus;
Maier, Dieter

Publication type:

Article

A 26-hour system of highly sensitive whole genome sequencing for emergency management of genetic diseases.

Published in:

Genome Medicine, 2015, v. 7, n. 1, p. 1, doi. 10.1186/s13073-015-0221-8

By:

Miller, Neil A.;
Farrow, Emily G.;
Gibson, Margaret;
Willig, Laurel K.;
Twist, Greyson;
Yoo, Byunggil;
Marrs, Tyler;
Corder, Shane;
Krivohlavek, Lisa;
Walter, Adam;
Petrikin, Josh E.;
Saunders, Carol J.;
Thiffault, Isabelle;
Soden, Sarah E.;
Smith, Laurie D.;
Dinwiddie, Darrell L.;
Herd, Suzanne;
Cakici, Julie A.;
Catreux, Severine;
Ruehle, Mike

Publication type:

Article

Rapid metagenomic identification of viral pathogens in clinical samples by real-time nanopore sequencing analysis.

Published in:

Genome Medicine, 2015, v. 7, n. 1, p. 1, doi. 10.1186/s13073-015-0220-9

By:

Greninger, Alexander L.;
Naccache, Samia N.;
Federman, Scot;
Guixia Yu;
Mbala, Placide;
Bres, Vanessa;
Stryke, Doug;
Bouquet, Jerome;
Somasekar, Sneha;
Linnen, Jeffrey M.;
Dodd, Roger;
Mulembakani, Prime;
Schneider, Bradley S.;
Muyembe-Tamfum, Jean-Jacques;
Stramer, Susan L.;
Chiu, Charles Y.

Publication type:

Article

The Murray collection of pre-antibiotic era Enterobacteriacae: a unique research resource.

Published in:

Genome Medicine, 2015, v. 7, n. 1, p. 1, doi. 10.1186/s13073-015-0222-7

By:

Baker, Kate S.;
Burnett, Edward;
McGregor, Hannah;
Deheer-Graham, Ana;
Boinett, Christine;
Langridge, Gemma C.;
Wailan, Alexander M.;
Cain, Amy K.;
Thomson, Nicholas R.;
Russell, Julie E.;
Parkhill, Julian

Publication type:

Article

Targeted therapies to improve CFTR function in cystic fibrosis.

Published in:

Genome Medicine, 2015, v. 7, n. 1, p. 1, doi. 10.1186/s13073-015-0223-6

By:

Brodlie, Malcolm;
Haq, Iram J.;
Roberts, Katie;
Elborn, J. Stuart

Publication type:

Article

Mutational landscapes of tongue carcinoma reveal recurrent mutations in genes of therapeutic and prognostic relevance.

Published in:

Genome Medicine, 2015, v. 7, n. 1, p. 1, doi. 10.1186/s13073-015-0219-2

By:

Vettore, Andre Luiz;
Ramnarayanan, Kalpana;
Poore, Gregory;
Lim, Kevin;
Choon Kiat Ong;
Kie Kyon Huang;
Hui Sun Leong;
Fui Teen Chong;
Kiat-Hon Lim, Tony;
Khong Lim, Weng;
Cutcutache, Ioana;
Mcpherson, John R.;
Yuka Suzuki;
Shenli Zhang;
Thakshayeni Skanthakumar;
Weining Wang;
Tan, Daniel SW;
Byoung Chul Cho;
Bin Tean Teh;
Rozen, Steve

Publication type:

Article

Omic personality: implications of stable transcript and methylation profiles for personalized medicine.

Published in:

Genome Medicine, 2015, v. 7, n. 1, p. 1, doi. 10.1186/s13073-015-0209-4

By:

Tabassum, Rubina;
Sivadas, Ambily;
Agrawal, Vartika;
Tian, Haozheng;
Arafat, Dalia;
Gibson, Greg

Publication type:

Article

Gene expression meta-analysis reveals immune response convergence on the IFNγ-STAT1-IRF1 axis and adaptive immune resistance mechanisms in lymphoma.

Published in:

Genome Medicine, 2015, v. 7, n. 1, p. 1, doi. 10.1186/s13073-015-0218-3

By:

Care, Matthew A.;
Westhead, David R.;
Tooze, Reuben M.

Publication type:

Article

Erratum to: Colorectal cancer screening: will non-invasive procedures triumph?

Published in:: 2015
Publication type:: Correction Notice

Erratum to: Why epistasis is important for tackling complex human disease genetics.

Published in:: 2015
Publication type:: Correction Notice

ClinLabGeneticist: a tool for clinical management of genetic variants from whole exome sequencing in clinical genetic laboratories.

Published in:

Genome Medicine, 2015, v. 7, n. 1, p. 1, doi. 10.1186/s13073-015-0207-6

By:

Jinlian Wang;
Jun Liao;
Jinglan Zhang;
Wei-Yi Cheng;
Hakenberg, Jörg;
Meng Ma;
Webb, Bryn D.;
Ramasamudram-chakravarthi, Rajasekar;
Karger, Lisa;
Mehta, Lakshmi;
Kornreich, Ruth;
Diaz, George A.;
Shuyu Li;
Edelmann, Lisa;
Rong Chen

Publication type:

Article

Exploring the cellular basis of human disease through a large-scale mapping of deleterious genes to cell types.

Published in:

Genome Medicine, 2015, v. 7, n. 1, p. 1, doi. 10.1186/s13073-015-0212-9

By:

Cornish, Alex J.;
Filippis, Ioannis;
David, Alessia;
Sternberg, Michael J. E.

Publication type:

Article

Exploring the cellular basis of human disease through a large-scale mapping of deleterious genes to cell types.

Published in:

Genome Medicine, 2015, v. 7, n. 1, p. 1, doi. 10.1186/s13073-015-0212-9

By:

Cornish, Alex J.;
Filippis, Ioannis;
David, Alessia;
Sternberg, Michael J. E.

Publication type:

Article

The successful search for genetic loci associated with depression.

Published in:

Genome Medicine, 2015, v. 7, n. 1, p. 1, doi. 10.1186/s13073-015-0217-4

By:

Rivera, Margarita;
McGuffin, Peter

Publication type:

Article

An assessment of sex bias in neurodevelopmental disorders.

Published in:

Genome Medicine, 2015, v. 7, n. 1, p. 1, doi. 10.1186/s13073-015-0216-5

By:

Polyak, Andrew;
Rosenfeld, Jill A.;
Girirajan, Santhosh

Publication type:

Article

Pharmacological inhibition of DNA-PK stimulates Cas9-mediated genome editing.

Published in:

Genome Medicine, 2015, v. 7, n. 1, p. 1, doi. 10.1186/s13073-015-0215-6

By:

Robert, Francis;
Barbeau, Mathilde;
Éthier, Sylvain;
Dostie, Josée;
Pelletier, Jerry

Publication type:

Article

Advancing epilepsy genetics in the genomic era.

Published in:

Genome Medicine, 2015, v. 7, n. 1, p. 1, doi. 10.1186/s13073-015-0214-7

By:

Myers, Candace T.;
Mefford, Heather C.

Publication type:

Article

DNA methylation loci associated with atopy and high serum IgE: a genome-wide application of recursive Random Forest feature selection.

Published in:

Genome Medicine, 2015, v. 7, n. 1, p. 1, doi. 10.1186/s13073-015-0213-8

By:

Everson, Todd M.;
Lyons, Genevieve;
Hongmei Zhang;
Soto-Ramírez, Nelís;
Lockett, Gabrielle A.;
Patil, Veeresh K.;
Merid, Simon K.;
Sӧderhӓll, Cilla;
Melén, Erik;
Holloway, John W.;
Arshad, S. Hasan;
Karmaus, Wilfried

Publication type:

Article

Mutational landscape of mucinous ovarian carcinoma and its neoplastic precursors.

Published in:

Genome Medicine, 2015, v. 7, n. 1, p. 1, doi. 10.1186/s13073-015-0210-y

By:

Ryland, Georgina L.;
Hunter, Sally M.;
Doyle, Maria A.;
Caramia, Franco;
Li, Jason;
Rowley, Simone M.;
Christie, Michael;
Allan, Prue E.;
Stephens, Andrew N.;
Bowtell, David D. L.;
Campbell, Ian G.;
Gorringe, Kylie L.

Publication type:

Article