Works matching IS 17528054 AND DT 2024 AND VI 17 AND IP 12

Results: 30

Augmented intelligence in precision medicine: Transforming clinical decision‐making with AI/ML and/or quantitative systems pharmacology models.
Published in:
CTS: Clinical & Translational Science, 2024, v. 17, n. 12, p. 1, doi. 10.1111/cts.70112
By:
- Venkatapurapu, Sai Phanindra;
- Gibbs, Megan;
- Kimko, Holly
Publication type:
Article
Longitudinal correlation of cerebrospinal fluid GFAP and the progression of cognition decline in different clinical subtypes of Parkinson's disease.
Published in:
CTS: Clinical & Translational Science, 2024, v. 17, n. 12, p. 1, doi. 10.1111/cts.70111
By:
- Liu, Yumei;
- Wang, Jing;
- Ning, Fangbo;
- Wang, Guojun;
- Xie, Anmu
Publication type:
Article
Pharmacokinetic study of polymyxin B in healthy subjects and subjects with renal insufficiency.
Published in:
CTS: Clinical & Translational Science, 2024, v. 17, n. 12, p. 1, doi. 10.1111/cts.70110
By:
- Fang, Yu‐Wei;
- Huang, Chien‐Hsien;
- Jang, Tsrang‐Neng;
- Lin, Shih‐Sen;
- Wang, Jing‐Tong;
- Huang, Yen‐Ta;
- Tsai, Ming Hsien
Publication type:
Article
Endogenous plasma riboflavin is not a viable BCRP biomarker in human.
Published in:
CTS: Clinical & Translational Science, 2024, v. 17, n. 12, p. 1, doi. 10.1111/cts.70109
By:
- Savaryn, John P.;
- Kikuchi, Ryota;
- Qian, Yuli;
- Ji, Qin C.;
- Jenkins, Gary J.;
- Bow, Daniel A. J.;
- Mohamed, Mohamed‐Eslam F.
Publication type:
Article
Pharmacogenomic variation and sedation outcomes during early intensive care unit admission: A pragmatic study.
Published in:
CTS: Clinical & Translational Science, 2024, v. 17, n. 12, p. 1, doi. 10.1111/cts.70107
By:
- Mohamed, Moataz E.;
- Nguyen, Tam T.;
- Larson, Jared;
- Schwake, Beatrice;
- Rivers, Zachary;
- Beilman, Greg;
- Skaar, Debra J.;
- Jacobson, Pamala A.
Publication type:
Article
Interindividual variability in CYP3A‐mediated venetoclax metabolism in vitro and in vivo in patients with chronic lymphocytic leukemia.
Published in:
CTS: Clinical & Translational Science, 2024, v. 17, n. 12, p. 1, doi. 10.1111/cts.70106
By:
- Lee, Jonghwa;
- Beers, Jessica L.;
- Cheng, Isabel;
- Truong, Vivian;
- Brown, Zachary;
- Muluneh, Benyam;
- Coombs, Catherine C.;
- Jackson, Klarissa D.
Publication type:
Article
Association of liver fibrosis scores with all‐cause and cardiovascular mortality in patients with heart failure.
Published in:
CTS: Clinical & Translational Science, 2024, v. 17, n. 12, p. 1, doi. 10.1111/cts.70104
By:
- Guo, Ziyu;
- Ye, Zixiang;
- Xu, Qinfeng;
- Li, Yike;
- Zheng, Jingang
Publication type:
Article
Effect of SLC22A1 polymorphism on the pharmacokinetics of proguanil in Korean: A semi‐physiologic population pharmacokinetic approach.
Published in:
CTS: Clinical & Translational Science, 2024, v. 17, n. 12, p. 1, doi. 10.1111/cts.70103
By:
- Khwarg, Juyoung;
- Yang, Eunsol;
- Park, Chan Song;
- Ji, Sang Chun;
- Yu, Kyung‐Sang;
- Lee, SeungHwan
Publication type:
Article
Safety of BI 1358894 in patients with major depressive disorder: Results and learnings from a phase II randomized decentralized clinical trial.
Published in:
CTS: Clinical & Translational Science, 2024, v. 17, n. 12, p. 1, doi. 10.1111/cts.70102
By:
- Reist, Christopher;
- Li, Peide;
- Le Nguyen, Thuy;
- Süssmuth, Sigurd D.
Publication type:
Article
Translational PK–PD model for in vivo CAR‐T‐cell therapy delivered using CAR mRNA‐loaded polymeric nanoparticle vector.
Published in:
CTS: Clinical & Translational Science, 2024, v. 17, n. 12, p. 1, doi. 10.1111/cts.70101
By:
- Kim, Se Jin;
- Mugundu, Ganesh M.;
- Singh, Aman P.
Publication type:
Article
An overview of drug‐induced sodium channel blockade and changes in cardiac conduction: Implications for drug safety.
Published in:
CTS: Clinical & Translational Science, 2024, v. 17, n. 12, p. 1, doi. 10.1111/cts.70098
By:
- Chaudhary, Khuram W.;
- Clancy, Colleen E.;
- Yang, Pei‐Chi;
- Pierson, Jennifer B.;
- Goldin, Alan L.;
- Koerner, John E.;
- Wisialowski, Todd A.;
- Valentin, Jean‐Pierre;
- Imredy, John P.;
- Lagrutta, Armando;
- Authier, Simon;
- Kleiman, Robert;
- Sager, Philip T.;
- Hoffmann, Peter;
- Pugsley, Michael K.
Publication type:
Article
Population pharmacokinetic analysis identifies an absorption process model for mycophenolic acid in patients with renal transplant.
Published in:
CTS: Clinical & Translational Science, 2024, v. 17, n. 12, p. 1, doi. 10.1111/cts.70097
By:
- Suzuki, Yuki;
- Matsunaga, Noriko;
- Aoyama, Takahiko;
- Ogami, Chika;
- Hasegawa, Chihiro;
- Iida, Satofumi;
- To, Hideto;
- Kitahara, Takashi;
- Tsuji, Yasuhiro
Publication type:
Article
Risk of artery dissection during systemic exposure to vascular endothelial growth factor pathway inhibitors.
Published in:
CTS: Clinical & Translational Science, 2024, v. 17, n. 12, p. 1, doi. 10.1111/cts.70096
By:
- Okui, Jun;
- Waki, Takashi;
- Kajiyama, Kazuhiro;
- Sawada, Sono;
- Watanabe, Shinya;
- Namba, Yukari;
- Kobayashi, Ayano;
- Kawarasaki, Shuichi;
- Amakasu, Kohei;
- Iguchi, Toyotaka;
- Horiuchi, Naoya;
- Uyama, Yoshiaki
Publication type:
Article
Safety, tolerability, pharmacokinetics, and pharmacodynamics of the oral allosteric TYK2 inhibitor ESK‐001 using a randomized, double‐blind, placebo‐controlled study design.
Published in:
CTS: Clinical & Translational Science, 2024, v. 17, n. 12, p. 1, doi. 10.1111/cts.70094
By:
- Ucpinar, Sibel;
- Kwan, Joyce K.;
- Hoffman, Joshua D.;
- Tilley, Mera K.;
- Douglas, Jeffrey A.;
- Rubio, Roman G.;
- Lu, Ruixiao;
- Nunn, Philip A.;
- Langrish, Claire L.
Publication type:
Article
Pharmacokinetics of infigratinib and its active metabolites in Chinese patients with advanced gastric cancer harboring FGFR2 gene amplification.
Published in:
CTS: Clinical & Translational Science, 2024, v. 17, n. 12, p. 1, doi. 10.1111/cts.70091
By:
- Yuan, Jiajia;
- Shen, Lin;
- Liu, Tian Shu;
- Xu, HuiTing;
- Yang, Jianwei;
- Wei, Jia;
- Jiang, Haiping;
- Deng, Yanhong;
- Pan, Hongming;
- Wang, Yusheng;
- Zhang, Xiaotian;
- Peng, Zhi;
- Qi, Changsong;
- Zhang, Lingli;
- Hsu, Peiwen;
- Song, Lin;
- Mu, Lei;
- Sun, Qiao;
- Gong, Jifang;
- Lyu, Cheng
Publication type:
Article
Effect of carrot intake on glucose tolerance, microbiota, and gene expression in a type 2 diabetes mouse model.
Published in:
CTS: Clinical & Translational Science, 2024, v. 17, n. 12, p. 1, doi. 10.1111/cts.70090
By:
- Kobaek‐Larsen, Morten;
- Maschek, Sina;
- Kolstrup, Stefanie Hansborg;
- Højlund, Kurt;
- Nielsen, Dennis Sandris;
- Hansen, Axel Kornerup;
- Christensen, Lars Porskjær
Publication type:
Article
Pharmacokinetics, pharmacodynamics, safety, and immunogenicity of HLX14 versus reference denosumab in healthy males: A randomized phase I study.
Published in:
CTS: Clinical & Translational Science, 2024, v. 17, n. 12, p. 1, doi. 10.1111/cts.70089
By:
- Li, Nanyang;
- Chu, Nannan;
- Zhu, Leilei;
- Wu, Xiaojie;
- Wei, Qiong;
- Wang, Jiahui;
- Hu, Xuhui;
- Yu, Haoyu;
- Wang, Qingyu;
- Yuan, Wei'an;
- Huang, Kai;
- Zhang, Jing
Publication type:
Article
Long‐term benefit of SGLT2 inhibitors to prevent heart failure hospitalization in patients with diabetes, with potential time‐varying benefit.
Published in:
CTS: Clinical & Translational Science, 2024, v. 17, n. 12, p. 1, doi. 10.1111/cts.70088
By:
- Takahashi, Yasuo;
- Minagawa, Kimino;
- Nagashima, Takuya;
- Hayakawa, Takashi;
- Akimoto, Hayato;
- Asai, Satoshi
Publication type:
Article
Syndication in science: Curated collaboration.
Published in:
CTS: Clinical & Translational Science, 2024, v. 17, n. 12, p. 1, doi. 10.1111/cts.70085
By:
- Hurry, David B.;
- Izmailova, Elena S.;
- Davies, Simon;
- Harari, Olivier;
- Stoch, S. Aubrey;
- Wagner, John A.
Publication type:
Article
Pharmacogenetic‐guided dosing for fluoropyrimidine (DPYD) and irinotecan (UGT1A1*28) chemotherapies for patients with cancer (PACIFIC‐PGx): A multicenter clinical trial.
Published in:
CTS: Clinical & Translational Science, 2024, v. 17, n. 12, p. 1, doi. 10.1111/cts.70083
By:
- Glewis, Sarah;
- Lingaratnam, Senthil;
- Lee, Benjamin;
- Campbell, Ian;
- IJzerman, Maarten;
- Fagery, Mussab;
- Harris, Sam;
- Georgiou, Chloe;
- Underhill, Craig;
- Warren, Mark;
- Campbell, Robert;
- Jayawardana, Madawa;
- Silva, S. Sandun M.;
- Martin, Jennifer H.;
- Tie, Jeanne;
- Alexander, Marliese;
- Michael, Michael
Publication type:
Article
Translational findings support regimen selection for first‐in‐human study of ubamatamab (MUC16 × CD3 bispecific antibody) in patients with recurrent ovarian cancer.
Published in:
CTS: Clinical & Translational Science, 2024, v. 17, n. 12, p. 1, doi. 10.1111/cts.70082
By:
- Zhu, Min;
- Madia, Priyanka;
- Crawford, Alison;
- Brouwer‐Visser, Jurriaan;
- Krueger, Pamela;
- Haber, Lauric;
- Peterman, Mary;
- Uldrick, Thomas S.;
- Miller, Elizabeth;
- Davis, John D.;
- Retter, Marc W.
Publication type:
Article
Efficacy and safety of 4‐hydroxy 2‐methyl‐N‐(5‐methyl‐2‐thiazolyl)‐2H‐1, 2‐benzothiazin‐3‐carboxamide 1,1‐dioxide, a fast‐acting meloxicam formulation, on moderate‐to‐severe pain following abdominal surgery: A phase III randomized controlled trial
Published in:
CTS: Clinical & Translational Science, 2024, v. 17, n. 12, p. 1, doi. 10.1111/cts.70081
By:
- Liu, Xiaohua;
- Zhao, Yanhua;
- Yang, Mengchang;
- Ren, Jinghua;
- Ouyang, Wen;
- Wang, Saiying;
- Shen, Yufei;
- Gao, Yuanli;
- Zhao, Ling;
- Qin, Zhong;
- Cao, Jun;
- Xia, Jiangyan;
- Zhou, Hongmei;
- Zeng, Haihua;
- Li, Jiangang;
- Li, Qiongcan;
- Jiang, Haitao;
- Zhou, Ruiren;
- Yuan, Kaiming;
- Jin, Shu'an
Publication type:
Article
Real‐world evidence in the cloud: Tutorial on developing an end‐to‐end data and analytics pipeline using Amazon Web Services resources.
Published in:
CTS: Clinical & Translational Science, 2024, v. 17, n. 12, p. 1, doi. 10.1111/cts.70078
By:
- Anderson, Wes;
- Bhatnagar, Roopal;
- Scollick, Keith;
- Schito, Marco;
- Walls, Ramona;
- Podichetty, Jagdeep T.
Publication type:
Article
Population pharmacokinetic analysis of quizartinib in patients with newly diagnosed FLT3‐internal‐tandem‐duplication‐positive acute myeloid leukemia.
Published in:
CTS: Clinical & Translational Science, 2024, v. 17, n. 12, p. 1, doi. 10.1111/cts.70074
By:
- Vaddady, Pavan;
- Glatard, Anaïs;
- Smania, Giovanni;
- Nakayama, Shintaro;
- Inoue, Hiroyuki;
- Kurumaddali, Abhinav;
- Abutarif, Malaz;
- Zheng, Ming
Publication type:
Article
Assessment of pharmacokinetics and tolerability following single‐dose administration of molnupiravir in participants with hepatic or renal impairment.
Published in:
CTS: Clinical & Translational Science, 2024, v. 17, n. 12, p. 1, doi. 10.1111/cts.70073
By:
- Duncan, Kelly E.;
- Carstens, Russ P.;
- Butterfield, Kristin L.;
- Jin, Yoon;
- Inbody, Laura R.;
- Schaeffer, Andrea K.;
- Matthews, Catherine Z.;
- Zhao, Tian;
- Patel, Shruti;
- Maas, Brian M.;
- Cheng, Mickie H.;
- Stoch, S. Aubrey;
- Kraft, Walter;
- Sanchez‐Crespo, Nelia;
- Rondon, Juan;
- Cruz, Kimberly;
- Vijil, Julio C.
Publication type:
Article
Radiomic‐based biomarkers: Transforming age and body composition metrics into personalized age‐informed indices.
Published in:
CTS: Clinical & Translational Science, 2024, v. 17, n. 12, p. 1, doi. 10.1111/cts.70062
By:
- Alikhani, Radin;
- Horbal, Steven R.;
- Rothberg, Amy E.;
- Pai, Manjunath P.
Publication type:
Article
Deconvoluting zavegepant drug–drug interactions: A phase I study to evaluate the effects of rifampin and itraconazole on zavegepant pharmacokinetics.
Published in:
CTS: Clinical & Translational Science, 2024, v. 17, n. 12, p. 1, doi. 10.1111/cts.70048
By:
- Bhardwaj, Rajinder;
- Malatesta, Jo Ann;
- Madonia, Jennifer;
- Anderson, Matt S.;
- Morris, Beth;
- Matschke, Kyle T.;
- Croop, Robert;
- Bertz, Richard;
- Liu, Jing
Publication type:
Article
Trends of in vitro pharmacological potency and in vivo pharmacokinetics parameters of modern drugs: Can the therapeutic/subtherapeutic dose be estimated from in vitro K<sub>i</sub> and pharmacokinetic parameters?
Published in:
CTS: Clinical & Translational Science, 2024, v. 17, n. 12, p. 1, doi. 10.1111/cts.70034
By:
- Tsuchitani, Toshiaki;
- Kato, Motohiro;
- Tomaru, Atsuko;
- Aoki, Yasunori;
- Sugiyama, Yuichi
Publication type:
Article
A systematic review of dexmedetomidine pharmacology in pediatric patients.
Published in:
CTS: Clinical & Translational Science, 2024, v. 17, n. 12, p. 1, doi. 10.1111/cts.70020
By:
- O'Kane, Aislinn;
- Quinney, Sara K.;
- Kinney, Emily;
- Bergstrom, Richard F.;
- Tillman, Emma M.
Publication type:
Article
Issue Information.
Published in:
CTS: Clinical & Translational Science, 2024, v. 17, n. 12, p. 1, doi. 10.1111/cts.13343
Publication type:
Article