Found: 40
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Aminobenzotriazole inhibits and induces several key drug metabolizing enzymes complicating its utility as a pan CYP inhibitor for reaction phenotyping.
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- CTS: Clinical & Translational Science, 2024, v. 17, n. 3, p. 1, doi. 10.1111/cts.13746
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No clinically relevant electrocardiogram effects in a randomized TQT study of single therapeutic/supratherapeutic rimegepant doses in healthy adults.
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- CTS: Clinical & Translational Science, 2024, v. 17, n. 3, p. 1, doi. 10.1111/cts.13727
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New insight of chemical constituents in Persea americana fruit against obesity via integrated pharmacology.
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- CTS: Clinical & Translational Science, 2024, v. 17, n. 3, p. 1, doi. 10.1111/cts.13778
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Proposing a framework to quantify the potential impact of pharmacokinetic drug–drug interactions caused by a new drug candidate by using real world data about the target patient population.
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- CTS: Clinical & Translational Science, 2024, v. 17, n. 3, p. 1, doi. 10.1111/cts.13741
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Cardiovascular safety of febuxostat versus allopurinol among the Asian patients with or without gout: A systematic review and meta‐analysis.
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- CTS: Clinical & Translational Science, 2024, v. 17, n. 3, p. 1, doi. 10.1111/cts.13757
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Social network analysis of the CaRE<sup>2</sup> health equity center: Team science in full display.
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- CTS: Clinical & Translational Science, 2024, v. 17, n. 3, p. 1, doi. 10.1111/cts.13747
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Bioavailability of three novel oral, sustained‐release pellets, relative to an immediate‐release tablet containing 500 mg flucytosine: A randomized, open‐label, crossover study in healthy volunteers.
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- CTS: Clinical & Translational Science, 2024, v. 17, n. 3, p. 1, doi. 10.1111/cts.13756
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Non‐targeted metabolomics for the identification of plasma metabolites associated with organic anion transporting polypeptide 1B1 function.
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- CTS: Clinical & Translational Science, 2024, v. 17, n. 3, p. 1, doi. 10.1111/cts.13773
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Patient, industry, and regulatory perspective on antibody‐drug conjugates dose optimization.
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- CTS: Clinical & Translational Science, 2024, v. 17, n. 3, p. 1, doi. 10.1111/cts.13759
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Mobocertinib: Mechanism of action, clinical, and translational science.
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- CTS: Clinical & Translational Science, 2024, v. 17, n. 3, p. 1, doi. 10.1111/cts.13766
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Pharmacokinetics and safety of erenumab in pediatric patients with migraine: A phase I, randomized, open‐label, multiple‐dose study.
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- CTS: Clinical & Translational Science, 2024, v. 17, n. 3, p. 1, doi. 10.1111/cts.13755
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Immunogenicity of avelumab in patients with metastatic Merkel cell carcinoma or advanced urothelial carcinoma.
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- CTS: Clinical & Translational Science, 2024, v. 17, n. 3, p. 1, doi. 10.1111/cts.13730
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Estimation of the benefit from pre‐emptive genotyping based on the nationwide cohort data in South Korea.
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- CTS: Clinical & Translational Science, 2024, v. 17, n. 3, p. 1, doi. 10.1111/cts.13772
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- Article
Plasma sCD146 is a potential biomarker for acute exacerbation of chronic obstructive pulmonary disease.
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- CTS: Clinical & Translational Science, 2024, v. 17, n. 3, p. 1, doi. 10.1111/cts.13754
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The oral IRAK4 inhibitors zabedosertib and BAY1830839 suppress local and systemic immune responses in a randomized trial in healthy male volunteers.
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- CTS: Clinical & Translational Science, 2024, v. 17, n. 3, p. 1, doi. 10.1111/cts.13771
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Clinical evaluation of PF614, a novel TAAP prodrug of oxycodone, versus OxyContin in a multi‐ascending dose study with a bioequivalence arm in healthy volunteers.
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- CTS: Clinical & Translational Science, 2024, v. 17, n. 3, p. 1, doi. 10.1111/cts.13765
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Pharmacogenetics of tamoxifen in breast cancer patients of African descent: Lack of data.
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- CTS: Clinical & Translational Science, 2024, v. 17, n. 3, p. 1, doi. 10.1111/cts.13761
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Bidirectional pharmacokinetics of doravirine, tenofovir, and feminizing hormones in transgender women (IDentify): A randomized crossover trial.
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- CTS: Clinical & Translational Science, 2024, v. 17, n. 3, p. 1, doi. 10.1111/cts.13721
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Tumor biomarkers in evaluating the severity and prognosis of idiopathic pulmonary arterial hypertension: A comprehensive analysis.
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- CTS: Clinical & Translational Science, 2024, v. 17, n. 3, p. 1, doi. 10.1111/cts.13751
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FAK mediates hypoxia‐induced pulmonary artery smooth muscle cell proliferation by modulating mitochondrial transcription termination factor 1/cyclin D1.
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- CTS: Clinical & Translational Science, 2024, v. 17, n. 3, p. 1, doi. 10.1111/cts.13767
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Safety, pharmacokinetics, and pharmacodynamics in healthy Chinese volunteers treated with SC0062, a highly selective endothelin‐A receptor antagonist.
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- CTS: Clinical & Translational Science, 2024, v. 17, n. 3, p. 1, doi. 10.1111/cts.13750
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Implementing pain, agitation, delirium, and sleep deprivation protocol in critically ill patients: A pilot study on pharmacological interventions.
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- CTS: Clinical & Translational Science, 2024, v. 17, n. 3, p. 1, doi. 10.1111/cts.13739
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Genetic predisposition and high exposure to colistin in the early treatment period as independent risk factors for colistin‐induced nephrotoxicity.
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- CTS: Clinical & Translational Science, 2024, v. 17, n. 3, p. 1, doi. 10.1111/cts.13764
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First‐in‐human study of JNJ‐67571244, a CD33 × CD3 bispecific antibody, in relapsed/refractory acute myeloid leukemia and myelodysplastic syndrome.
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- CTS: Clinical & Translational Science, 2024, v. 17, n. 3, p. 1, doi. 10.1111/cts.13742
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Evaluation of the usefulness of plasma 4β‐hydroxycholesterol concentration normalized by 4α‐hydroxycholesterol for accurate CYP3A phenotyping.
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- CTS: Clinical & Translational Science, 2024, v. 17, n. 3, p. 1, doi. 10.1111/cts.13768
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Clinical pharmacokinetics of atropine oral gel formulation in healthy volunteers.
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- CTS: Clinical & Translational Science, 2024, v. 17, n. 3, p. 1, doi. 10.1111/cts.13753
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Investigating the role of an immediate early gene FOS as a potential regulator of autophagic response to hypoglycemia in embryonic hypothalamic neurons.
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- CTS: Clinical & Translational Science, 2024, v. 17, n. 3, p. 1, doi. 10.1111/cts.13749
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The impact of skin color and tone on histamine iontophoresis and Doppler flowmetry measurements as a pharmacodynamic biomarker.
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- CTS: Clinical & Translational Science, 2024, v. 17, n. 3, p. 1, doi. 10.1111/cts.13777
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Knowledge and attitudes on implementing cardiovascular pharmacogenomic testing.
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- CTS: Clinical & Translational Science, 2024, v. 17, n. 3, p. 1, doi. 10.1111/cts.13737
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Nrf‐2/ROS/NF‐κB pathway is modulated by cynarin in human mesenchymal stem cells in vitro from ankylosing spondylitis.
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- CTS: Clinical & Translational Science, 2024, v. 17, n. 3, p. 1, doi. 10.1111/cts.13748
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Lipidomic changes in a novel sepsis outcome‐based analysis reveals potent pro‐inflammatory and pro‐resolving signaling lipids.
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- CTS: Clinical & Translational Science, 2024, v. 17, n. 3, p. 1, doi. 10.1111/cts.13745
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Ischemia‐induced cardiac dysfunction is exacerbated in adiponectin‐knockout mice due to impaired autophagy flux.
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- CTS: Clinical & Translational Science, 2024, v. 17, n. 3, p. 1, doi. 10.1111/cts.13758
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Crushing tablets or sprinkling capsules: Implications for clinical strategy and study performance based on BE studies of rivaroxaban and deferasirox.
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- CTS: Clinical & Translational Science, 2024, v. 17, n. 3, p. 1, doi. 10.1111/cts.13752
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Natural intestinal metabolite xylitol reduces BRD4 levels to mitigate renal fibrosis.
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- CTS: Clinical & Translational Science, 2024, v. 17, n. 3, p. 1, doi. 10.1111/cts.13770
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In vitro PK/PD modeling of tyrosine kinase inhibitors in non‐small cell lung cancer cell lines.
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- CTS: Clinical & Translational Science, 2024, v. 17, n. 3, p. 1, doi. 10.1111/cts.13714
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Effects of meal type on the bioavailability of vutiglabridin, a novel anti‐obesity agent, in healthy subjects.
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- CTS: Clinical & Translational Science, 2024, v. 17, n. 3, p. 1, doi. 10.1111/cts.13744
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Population pharmacokinetics, enzyme occupancy, and pharmacodynamic modeling of soticlestat in patients with developmental and epileptic encephalopathies.
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- CTS: Clinical & Translational Science, 2024, v. 17, n. 3, p. 1, doi. 10.1111/cts.13722
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Clinical dose rationale of tislelizumab in patients with solid or hematological advanced tumors.
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- CTS: Clinical & Translational Science, 2024, v. 17, n. 3, p. 1, doi. 10.1111/cts.13769
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Machine learning identifies fatigue as a key symptom of fibromyalgia reflected in tyrosine, purine, pyrimidine, and glutaminergic metabolism.
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- CTS: Clinical & Translational Science, 2024, v. 17, n. 3, p. 1, doi. 10.1111/cts.13740
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Issue Information.
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- CTS: Clinical & Translational Science, 2024, v. 17, n. 3, p. 1, doi. 10.1111/cts.13334
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- Article