Works matching IS 17501326 AND DT 2025 AND VI 20 AND IP 1

Results: 76

sPLA2-IIA modifies progranulin deficiency phenotypes in mouse models.

Published in:

Molecular Neurodegeneration, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13024-025-00863-8

By:

Yang, Cha;
Du, Huan;
Lee, Gwang Bin;
Uematsu, Masaaki;
He, Weiguo;
Doré, Etienne;
Yu, Weizhi;
Sanford, Ethan J.;
Smolka, Marcus B.;
Boilard, Eric;
Baskin, Jeremy M.;
Hao, Ling;
Hu, Fenghua

Publication type:

Article

In Memoriam of Edward H. Koo, MD 1954–2025.

Published in:

Molecular Neurodegeneration, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13024-025-00862-9

By:

Zheng, Hui;
Galasko, Douglas;
Sisodia, Sangram S.

Publication type:

Article

Extracellular vesicles in TDP-43 proteinopathies: pathogenesis and biomarker potential.

Published in:

Molecular Neurodegeneration, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13024-025-00859-4

By:

Dellar, Elizabeth R.;
Nikel, Lara;
Fowler, Stephanie;
Vahsen, Björn F.;
Dafinca, Ruxandra;
Feneberg, Emily;
Talbot, Kevin;
Turner, Martin R.;
Thompson, Alexander G.

Publication type:

Article

Alpha synuclein co-pathology is associated with accelerated amyloid-driven tau accumulation in Alzheimer's disease.

Published in:

Molecular Neurodegeneration, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13024-025-00822-3

By:

Franzmeier, Nicolai;
Roemer-Cassiano, Sebastian Niclas;
Bernhardt, Alexander Maximilian;
Dehsarvi, Amir;
Dewenter, Anna;
Steward, Anna;
Biel, Davina;
Frontzkowski, Lukas;
Zhu, Zeyu;
Gnörich, Johannes;
Pescoller, Julia;
Wagner, Fabian;
Hirsch, Fabian;
de Bruin, Hannah;
Ossenkoppele, Rik;
Palleis, Carla;
Strübing, Felix;
Schöll, Michael;
Levin, Johannes;
Brendel, Matthias

Publication type:

Article

Alzheimer’s disease pathogenesis: standing at the crossroad of lipid metabolism and immune response.

Published in:

Molecular Neurodegeneration, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13024-025-00857-6

By:

Wang, Zitong;
Zhang, Ling;
Qin, Chuan

Publication type:

Article

Alzheimer’s disease pathogenesis: standing at the crossroad of lipid metabolism and immune response.

Published in:

Molecular Neurodegeneration, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13024-025-00857-6

By:

Wang, Zitong;
Zhang, Ling;
Qin, Chuan

Publication type:

Article

The many connections of UFMylation with Alzheimer’s disease: a comprehensive review.

Published in:

Molecular Neurodegeneration, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13024-025-00855-8

By:

Yan, Tingxiang;
Clarkson, Benjamin D.;
Lou, Zhenkun;
Springer, Wolfdieter;
Fiesel, Fabienne C.

Publication type:

Article

The many connections of UFMylation with Alzheimer’s disease: a comprehensive review.

Published in:

Molecular Neurodegeneration, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13024-025-00855-8

By:

Yan, Tingxiang;
Clarkson, Benjamin D.;
Lou, Zhenkun;
Springer, Wolfdieter;
Fiesel, Fabienne C.

Publication type:

Article

RNA-binding proteins in ALS and FTD: from pathogenic mechanisms to therapeutic insights.

Published in:

Molecular Neurodegeneration, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13024-025-00851-y

By:

Rummens, Jens;
Da Cruz, Sandrine

Publication type:

Article

RNA-binding proteins in ALS and FTD: from pathogenic mechanisms to therapeutic insights.

Published in:

Molecular Neurodegeneration, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13024-025-00851-y

By:

Rummens, Jens;
Da Cruz, Sandrine

Publication type:

Article

The UNC5C T835M mutation associated with Alzheimer’s disease leads to neurodegeneration involving oxidative stress and hippocampal atrophy in aged mice.

Published in:

Molecular Neurodegeneration, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13024-025-00850-z

By:

Karunakaran, Devi Krishna Priya;
Ley, Makenna;
Guo, Joanna;
Khatri, Ammaarah;
Sadleir, Katherine;
Popovic, Jelena;
Upadhyay, Arun Kumar;
Savas, Jeffrey;
Procissi, Daniele;
Atwal, Jasvinder;
Vassar, Robert

Publication type:

Article

The UNC5C T835M mutation associated with Alzheimer’s disease leads to neurodegeneration involving oxidative stress and hippocampal atrophy in aged mice.

Published in:

Molecular Neurodegeneration, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13024-025-00850-z

By:

Karunakaran, Devi Krishna Priya;
Ley, Makenna;
Guo, Joanna;
Khatri, Ammaarah;
Sadleir, Katherine;
Popovic, Jelena;
Upadhyay, Arun Kumar;
Savas, Jeffrey;
Procissi, Daniele;
Atwal, Jasvinder;
Vassar, Robert

Publication type:

Article

Early transcriptional and cellular abnormalities in choroid plexus of a mouse model of Alzheimer's disease.

Published in:

Molecular Neurodegeneration, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13024-025-00853-w

By:

Yan, Zhong-Jiang;
Ye, Maosen;
Li, Jiexi;
Zhang, Deng-Feng;
Yao, Yong-Gang

Publication type:

Article

Increased TMEM106B levels lead to lysosomal dysfunction which affects synaptic signaling and neuronal health.

Published in:

Molecular Neurodegeneration, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13024-025-00831-2

By:

Perneel, Jolien;
Lastra Osua, Miranda;
Alidadiani, Sara;
Peeters, Nele;
De Witte, Linus;
Heeman, Bavo;
Manzella, Simona;
De Rycke, Riet;
Brooks, Mieu;
Perkerson, Ralph B.;
Calus, Elke;
De Coster, Wouter;
Neumann, Manuela;
Mackenzie, Ian R. A.;
Van Dam, Debby;
Asselbergh, Bob;
Ellender, Tommas;
Zhou, Xiaolai;
Rademakers, Rosa

Publication type:

Article

Research models to study lewy body dementia.

Published in:

Molecular Neurodegeneration, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13024-025-00837-w

By:

Boschen, Suelen Lucio;
A. Mukerjee, Aarushi;
H. Faroqi, Ayman;
E. Rabichow, Ben;
Fryer, John

Publication type:

Article

CD2AP at the junction of nephropathy and Alzheimer's disease.

Published in:

Molecular Neurodegeneration, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13024-025-00852-x

By:

Vandal, Milene;
Janmaleki, Mohsen;
Rea, Isabel;
Gunn, Colin;
Hirai, Sotaro;
Biernaskie, Jeff;
Chun, Justin;
Gordon, Grant;
Shaw, Andrey;
Sanati-Nezhad, Amir;
Pfeffer, Gerald;
Calon, Frederic;
Nguyen, Minh Dang

Publication type:

Article

Bridging systemic metabolic dysfunction and Alzheimer's disease: the liver interface.

Published in:

Molecular Neurodegeneration, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13024-025-00849-6

By:

Song, Dan;
Li, Yang;
Yang, Ling-Ling;
Luo, Ya-Xi;
Yao, Xiu-Qing

Publication type:

Article

Immunotherapy against tau fragment diminishes AD pathology, improving synaptic function and cognition.

Published in:

Molecular Neurodegeneration, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13024-025-00854-9

By:

Xiang, Jie;
Qian, Zhengjiang;
Xi, Ye;
Wei, Yanuo;
Wang, Guangxing;
Liu, Xia;
Wang, Zhi-Hao;
Zhang, Zhentao;
Wu, Shengxi;
Ye, Keqiang

Publication type:

Article

Mutations in NEK1 cause ciliary dysfunction as a novel pathogenic mechanism in amyotrophic lateral sclerosis.

Published in:

Molecular Neurodegeneration, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13024-025-00848-7

By:

Noh, Min-Young;
Oh, Seong-il;
Kim, Young-Eun;
Cha, Sun Joo;
Sung, Wonjae;
Oh, Ki-Wook;
Park, Yurim;
Mun, Ji Young;
Ki, Chang-Seok;
Nahm, Minyeop;
Kim, Seung Hyun

Publication type:

Article

Network analysis of the cerebrospinal fluid proteome reveals shared and unique differences between sporadic and familial forms of amyotrophic lateral sclerosis.

Published in:

Molecular Neurodegeneration, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13024-025-00838-9

By:

Trautwig, Adam N.;
Fox, Edward J.;
Dammer, Eric B.;
Shantaraman, Anantharaman;
Ping, Lingyan;
Duong, Duc M.;
Watson, Caroline M.;
Wu, Fang;
Asress, Seneshaw;
Guo, Qi;
Levey, Allan I.;
Lah, James J.;
Verde, Federico;
Doretti, Alberto;
Ratti, Antonia;
Ticozzi, Nicola;
Ly, Cindy V.;
Miller, Timothy M.;
Garret, Mark A.;
Berry, James D.

Publication type:

Article

Mouse models of Anti-Aβ immunotherapies.

Published in:

Molecular Neurodegeneration, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13024-025-00836-x

By:

Pikus, Philip;
Turner, R. Scott;
Rebeck, G. William

Publication type:

Article

Cellular and molecular mechanisms of pathological tau phosphorylation in traumatic brain injury: implications for chronic traumatic encephalopathy.

Published in:

Molecular Neurodegeneration, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13024-025-00842-z

By:

Donison, Neil;
Palik, Jacqueline;
Volkening, Kathryn;
Strong, Michael J.

Publication type:

Article

Evidence suggesting that microglia make amyloid from neuronally expressed APP: a hypothesis.

Published in:

Molecular Neurodegeneration, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13024-025-00847-8

By:

Hardy, John;
Lewis, Patrick

Publication type:

Article

Cautions on utilizing plasma GFAP level as a biomarker for reactive astrocytes in neurodegenerative diseases.

Published in:

Molecular Neurodegeneration, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13024-025-00846-9

By:

Youn, Wongu;
Yun, Mijin;
Lee, C. Justin;
Schöll, Michael

Publication type:

Article

Molecular mechanisms and consequences of TDP-43 phosphorylation in neurodegeneration.

Published in:

Molecular Neurodegeneration, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13024-025-00839-8

By:

Kellett, Elise A.;
Bademosi, Adekunle T.;
Walker, Adam K.

Publication type:

Article

Cerebrospinal fluid proteome profiling across the Alzheimer's disease continuum: a step towards solving the equation for 'X'.

Published in:

Molecular Neurodegeneration, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13024-025-00841-0

By:

Weiner, Sophia;
Sauer, Mathias;
Montoliu-Gaya, Laia;
Benedet, Andrea L.;
Ashton, Nicholas J.;
Gonzalez-Ortiz, Fernando;
Simrén, Joel;
Rahmouni, Nesrine;
Tissot, Cecile;
Therriault, Joseph;
Servaes, Stijn;
Stevenson, Jenna;
Leinonen, Ville;
Rauramaa, Tuomas;
Hiltunen, Mikko;
Rosa-Neto, Pedro;
Blennow, Kaj;
Zetterberg, Henrik;
Gobom, Johan

Publication type:

Article

Alzheimer's disease protective allele of Clusterin modulates neuronal excitability through lipid-droplet-mediated neuron-glia communication.

Published in:

Molecular Neurodegeneration, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13024-025-00840-1

By:

Zhao, Xiaojie;
Li, Yan;
Zhang, Siwei;
Sudwarts, Ari;
Zhang, Hanwen;
Kozlova, Alena;
Moulton, Matthew J.;
Goodman, Lindsey D.;
Pang, Zhiping P.;
Sanders, Alan R.;
Bellen, Hugo J.;
Thinakaran, Gopal;
Duan, Jubao

Publication type:

Article

Monoallelic TYROBP deletion is a novel risk factor for Alzheimer's disease.

Published in:

Molecular Neurodegeneration, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13024-025-00830-3

By:

Martiskainen, Henna;
Willman, Roosa-Maria;
Harju, Päivi;
Heikkinen, Sami;
Heiskanen, Mette;
Müller, Stephan A.;
Sinisalo, Rosa;
Takalo, Mari;
Mäkinen, Petra;
Kuulasmaa, Teemu;
Pekkala, Viivi;
Galván del Rey, Ana;
Juopperi, Sini-Pauliina;
Jeskanen, Heli;
Kervinen, Inka;
Saastamoinen, Kirsi;
FinnGen;
Palotie, Aarno;
Daly, Mark;
Riley-Gills, Bridget

Publication type:

Article

TDP-43 seeding activity in the olfactory mucosa of patients with amyotrophic lateral sclerosis.

Published in:

Molecular Neurodegeneration, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13024-025-00833-0

By:

Vizziello, Maria;
Dellarole, Ilaria Linda;
Ciullini, Arianna;
Pascuzzo, Riccardo;
Lombardo, Annalisa;
Bellandi, Floriana;
Celauro, Luigi;
Battipaglia, Claudia;
Ciusani, Emilio;
Rizzo, Ambra;
Catania, Marcella;
Devigili, Grazia;
Della Seta, Sara Adriana;
Margiotta, Valentina;
Consonni, Monica;
Faltracco, Veronica;
Tiraboschi, Pietro;
Riva, Nilo;
Portaleone, Sara Maria Silvia;
Zanusso, Gianluigi

Publication type:

Article

Spectrum of γ-Secretase dysfunction as a unifying predictor of ADAD age at onset across PSEN1, PSEN2 and APP causal genes.

Published in:

Molecular Neurodegeneration, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13024-025-00832-1

By:

Fernández, Sara Gutiérrez;
Oria, Cristina Gan;
Petit, Dieter;
Annaert, Wim;
Ringman, John M.;
Fox, Nick C.;
Ryan, Natalie S.;
Chávez-Gutiérrez, Lucía

Publication type:

Article

Multi-region brain transcriptomic analysis of amyotrophic lateral sclerosis reveals widespread RNA alterations and substantial cerebellum involvement.

Published in:

Molecular Neurodegeneration, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13024-025-00820-5

By:

Grima, Natalie;
Smith, Andrew N.;
Shepherd, Claire E.;
Henden, Lyndal;
Zaw, Thiri;
Carroll, Luke;
Rowe, Dominic B.;
Kiernan, Matthew C.;
Blair, Ian P.;
Williams, Kelly L.

Publication type:

Article

Apolipoprotein E in Alzheimer's disease: molecular insights and therapeutic opportunities.

Published in:

Molecular Neurodegeneration, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13024-025-00843-y

By:

Belaidi, Abdel Ali;
Bush, Ashley I.;
Ayton, Scott

Publication type:

Article

Multi-region brain transcriptomic analysis of amyotrophic lateral sclerosis reveals widespread RNA alterations and substantial cerebellum involvement.

Published in:

Molecular Neurodegeneration, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13024-025-00820-5

By:

Grima, Natalie;
Smith, Andrew N.;
Shepherd, Claire E.;
Henden, Lyndal;
Zaw, Thiri;
Carroll, Luke;
Rowe, Dominic B.;
Kiernan, Matthew C.;
Blair, Ian P.;
Williams, Kelly L.

Publication type:

Article

Inhibition of soluble epoxide hydrolase confers neuroprotection and restores microglial homeostasis in a tauopathy mouse model.

Published in:

Molecular Neurodegeneration, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13024-025-00844-x

By:

Wang, Shuo;
Qi, Chuangye;
Rajpurohit, Chetan;
Ghosh, Baijayanti;
Xiong, Wen;
Wang, Baiping;
Qi, Yanyan;
Hwang, Sung Hee;
Hammock, Bruce D.;
Li, Hongjie;
Gan, Li;
Zheng, Hui

Publication type:

Article

Therapeutic effects of adipose-derived mesenchymal stem cells combined with glymphatic system activation in prion disease.

Published in:

Molecular Neurodegeneration, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13024-025-00835-y

By:

Zayed, Mohammed;
Kim, Yong-Chan;
Jeong, Byung-Hoon

Publication type:

Article

TREM2 and sTREM2 in Alzheimer's disease: from mechanisms to therapies.

Published in:

Molecular Neurodegeneration, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13024-025-00834-z

By:

Zhang, Lianshuai;
Xiang, Xianyuan;
Li, Yahui;
Bu, Guojun;
Chen, Xiao-Fen

Publication type:

Article

A reciprocal relationship between markers of genomic DNA damage and alpha-synuclein pathology in dementia with Lewy bodies.

Published in:

Molecular Neurodegeneration, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13024-025-00813-4

By:

Koss, David J.;
Todd, Olivia;
Menon, Hariharan;
Anderson, Zoe;
Yang, Tamsin;
Findlay, Lucas;
Graham, Ben;
Palmowski, Pawel;
Porter, Andrew;
Morrice, Nicola;
Walker, Lauren;
Attems, Johannes;
Ghanem, Simona S.;
El-Agnaf, Omar;
LeBeau, Fiona EN.;
Erskine, Daniel;
Outeiro, Tiago F.

Publication type:

Article

ASO-mediated knock-down of GPNMB in mutant-GRN and in Grn-deficient peripheral myeloid cells disrupts lysosomal function and immune responses.

Published in:

Molecular Neurodegeneration, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13024-025-00829-w

By:

Wallings, Rebecca L.;
Gillett, Drew A.;
Staley, Hannah A.;
Mahn, Savanna;
Mark, Julian;
Neighbarger, Noelle;
Kordasiewicz, Holly;
Hirst, Warren D.;
Tansey, Malú Gámez

Publication type:

Article

A stress-dependent TDP-43 SUMOylation program preserves neuronal function.

Published in:

Molecular Neurodegeneration, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13024-025-00826-z

By:

Suk, Terry R.;
Part, Caroline E.;
Zhang, Jenny L.;
Nguyen, Trina T.;
Heer, Meghan M.;
Caballero-Gómez, Alejandro;
Grybas, Veronica S.;
McKeever, Paul M.;
Nguyen, Benjamin;
Ali, Tahir;
Callaghan, Steve M.;
Woulfe, John M.;
Robertson, Janice;
Rousseaux, Maxime W. C.

Publication type:

Article

Decoding microglial immunometabolism: a new frontier in Alzheimer's disease research.

Published in:

Molecular Neurodegeneration, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13024-025-00825-0

By:

Jung, Eun Sun;
Choi, Hayoung;
Mook-Jung, Inhee

Publication type:

Article

Immune cell metabolic dysfunction in Parkinson's disease.

Published in:

Molecular Neurodegeneration, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13024-025-00827-y

By:

Mark, Julian R.;
Tansey, Malú Gámez

Publication type:

Article

The role of n-3-derived specialised pro-resolving mediators (SPMs) in microglial mitochondrial respiration and inflammation resolution in Alzheimer's disease.

Published in:

Molecular Neurodegeneration, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13024-025-00824-1

By:

Slayo, Mary;
Rummel, Christoph;
Singhaarachchi, Pasindu Hansana;
Feldotto, Martin;
Spencer, Sarah J.

Publication type:

Article

Immune modulation to treat Alzheimer's disease.

Published in:

Molecular Neurodegeneration, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13024-025-00828-x

By:

Duggan, Michael R.;
Morgan, David G.;
Price, Brittani R.;
Rajbanshi, Binita;
Martin-Peña, Alfonso;
Tansey, Malú Gámez;
Walker, Keenan A.

Publication type:

Article

Alpha synuclein co-pathology is associated with accelerated amyloid-driven tau accumulation in Alzheimer's disease.

Published in:

Molecular Neurodegeneration, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13024-025-00822-3

By:

Franzmeier, Nicolai;
Roemer-Cassiano, Sebastian Niclas;
Bernhardt, Alexander Maximilian;
Dehsarvi, Amir;
Dewenter, Anna;
Steward, Anna;
Biel, Davina;
Frontzkowski, Lukas;
Zhu, Zeyu;
Gnörich, Johannes;
Pescoller, Julia;
Wagner, Fabian;
Hirsch, Fabian;
de Bruin, Hannah;
Ossenkoppele, Rik;
Palleis, Carla;
Strübing, Felix;
Schöll, Michael;
Levin, Johannes;
Brendel, Matthias

Publication type:

Article

Alzheimer's disease neuropathology and its estimation with fluid and imaging biomarkers.

Published in:

2025

By:

Thal, Dietmar Rudolf;
Poesen, Koen;
Vandenberghe, Rik;
De Meyer, Steffi

Publication type:

Literature Review

Probe-dependent Proximity Profiling (ProPPr) Uncovers Similarities and Differences in Phospho-Tau-Associated Proteomes Between Tauopathies.

Published in:

Molecular Neurodegeneration, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13024-025-00817-0

By:

Morderer, Dmytro;
Wren, Melissa C.;
Liu, Feilin;
Kouri, Naomi;
Maistrenko, Anastasiia;
Khalil, Bilal;
Pobitzer, Nora;
Salemi, Michelle R.;
Phinney, Brett S.;
Bu, Guojun;
Zhao, Na;
Dickson, Dennis W.;
Murray, Melissa E.;
Rossoll, Wilfried

Publication type:

Article

Comprehensive cross-sectional and longitudinal comparisons of plasma glial fibrillary acidic protein and neurofilament light across FTD spectrum disorders.

Published in:

Molecular Neurodegeneration, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13024-025-00821-4

By:

Sheth, Udit;
Öijerstedt, Linn;
Heckman, Michael G.;
White, Launia J.;
Heuer, Hilary W.;
Lario Lago, Argentina;
Forsberg, Leah K.;
Faber, Kelley M.;
Foroud, Tatiana M.;
Rademakers, Rosa;
Ramos, Eliana Marisa;
Appleby, Brian S.;
Bozoki, Andrea C.;
Darby, R. Ryan;
Dickerson, Bradford C.;
Domoto-Reilly, Kimiko;
Galasko, Douglas R.;
Ghoshal, Nupur;
Graff-Radford, Neill R.;
Grant, Ian M.

Publication type:

Article

A versatile mouse model to advance human microglia transplantation research in neurodegenerative diseases.

Published in:

Molecular Neurodegeneration, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13024-025-00823-2

By:

Serneels, Lutgarde;
Sierksma, Annerieke;
Pasciuto, Emanuela;
Geric, Ivana;
Nair, Arya;
Martinez-Muriana, Anna;
Snellinx, An;
De Strooper, Bart

Publication type:

Article

Inactivation of NLRP3 inflammasome by dephosphorylation at Serine 658 alleviates glial inflammation in the mouse model of Parkinson's disease.

Published in:

Molecular Neurodegeneration, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13024-025-00818-z

By:

Zhu, Rong-Xin;
Han, Rui-Xue;
Chen, Yue-Han;
Huang, Lei;
Liu, Ting;
Jiang, Jingwei;
Wang, Cong;
Cao, Lei;
Liu, Yang;
Lu, Ming

Publication type:

Article

Age-dependent progression from clearance to vulnerability in the early response of periventricular microglia to α-synuclein toxic species.

Published in:

Molecular Neurodegeneration, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13024-025-00816-1

By:

Sirerol-Piquer, Mª Salomé;
Perez-Villalba, Ana;
Duart-Abadia, Pere;
Belenguer, Germán;
Gómez-Pinedo, Ulises;
Blasco-Chamarro, Laura;
Carrillo-Barberà, Pau;
Pérez-Cañamás, Azucena;
Navarro-Garrido, Victoria;
Dehay, Benjamin;
Vila, Miquel;
Vitorica, Javier;
Pérez-Sánchez, Francisco;
Fariñas, Isabel

Publication type:

Article