Works matching IS 17501326 AND DT 2023

Results: 101

Advanced structural brain aging in preclinical autosomal dominant Alzheimer disease.

Published in:

Molecular Neurodegeneration, 2023, p. 1, doi. 10.1186/s13024-023-00688-3

By:

Millar, Peter R;
Gordon, Brian A;
Wisch, Julie K;
Schultz, Stephanie A;
Benzinger, Tammie LS;
Cruchaga, Carlos;
Hassenstab, Jason J;
Ibanez, Laura;
Karch, Celeste;
Llibre-Guerra, Jorge J;
Morris, John C;
Perrin, Richard J;
Supnet-Bell, Charlene;
Xiong, Chengjie;
Allegri, Ricardo F;
Berman, Sarah B;
Chhatwal, Jasmeer P;
Chrem Mendez, Patricio A;
Day, Gregory S;
Hofmann, Anna

Publication type:

Article

Correction: Multi-modal proteomic characterization of lysosomal function and proteostasis in progranulin-deficient neurons.

Published in:

2023

By:

Hasan, Saadia;
Fernandopulle, Michael S.;
Humble, Stewart W.;
Frankenfield, Ashley M.;
Li, Haorong;
Prestil, Ryan;
Johnson, Kory R.;
Ryan, Brent J.;
Wade-Martins, Richard;
Ward, Michael E.;
Hao, Ling

Publication type:

Correction Notice

Amyloid-β specific regulatory T cells attenuate Alzheimer's disease pathobiology in APP/PS1 mice.

Published in:

Molecular Neurodegeneration, 2023, v. 18, n. 1, p. 1, doi. 10.1186/s13024-023-00692-7

By:

Yeapuri, Pravin;
Machhi, Jatin;
Lu, Yaman;
Abdelmoaty, Mai Mohamed;
Kadry, Rana;
Patel, Milankumar;
Bhattarai, Shaurav;
Lu, Eugene;
Namminga, Krista L.;
Olson, Katherine E.;
Foster, Emma G.;
Mosley, R. Lee;
Gendelman, Howard E.

Publication type:

Article

Advanced structural brain aging in preclinical autosomal dominant Alzheimer disease.

Published in:

Molecular Neurodegeneration, 2023, v. 18, n. 1, p. N.PAG, doi. 10.1186/s13024-023-00688-3

By:

Millar, Peter R;
Gordon, Brian A;
Wisch, Julie K;
Schultz, Stephanie A;
Benzinger, Tammie LS;
Cruchaga, Carlos;
Hassenstab, Jason J;
Ibanez, Laura;
Karch, Celeste;
Llibre-Guerra, Jorge J;
Morris, John C;
Perrin, Richard J;
Supnet-Bell, Charlene;
Xiong, Chengjie;
Allegri, Ricardo F;
Berman, Sarah B;
Chhatwal, Jasmeer P;
Chrem Mendez, Patricio A;
Day, Gregory S;
Hofmann, Anna

Publication type:

Article

Translational profiling identifies sex-specific metabolic and epigenetic reprogramming of cortical microglia/macrophages in APPPS1-21 mice with an antibiotic-perturbed-microbiome.

Published in:

Molecular Neurodegeneration, 2023, v. 18, n. 1, p. 1, doi. 10.1186/s13024-023-00668-7

By:

Shaik, Shabana M.;
Cao, Yajun;
Gogola, Joseph V.;
Dodiya, Hemraj B.;
Zhang, Xulun;
Boutej, Hejer;
Han, Weinong;
Kriz, Jasna;
Sisodia, Sangram S.

Publication type:

Article

MLKL deficiency alleviates neuroinflammation and motor deficits in the α-synuclein transgenic mouse model of Parkinson's disease.

Published in:

Molecular Neurodegeneration, 2023, v. 18, n. 1, p. 1, doi. 10.1186/s13024-023-00686-5

By:

Geng, Lu;
Gao, Wenqing;
Saiyin, Hexige;
Li, Yuanyuan;
Zeng, Yu;
Zhang, Zhifei;
Li, Xue;
Liu, Zuolong;
Gao, Qiang;
An, Ping;
Jiang, Ning;
Yu, Xiaofei;
Chen, Xiangjun;
Li, Suhua;
Chen, Lei;
Lu, Boxun;
Li, Aiqun;
Chen, Guoyuan;
Shen, Yidong;
Zhang, Haibing

Publication type:

Article

Sleep restoration by optogenetic targeting of GABAergic neurons reprograms microglia and ameliorates pathological phenotypes in an Alzheimer's disease model.

Published in:

Molecular Neurodegeneration, 2023, v. 18, n. 1, p. 1, doi. 10.1186/s13024-023-00682-9

By:

Zhao, Qiuchen;
Maci, Megi;
Miller, Morgan R.;
Zhou, Heng;
Zhang, Fang;
Algamal, Moustafa;
Lee, Yee Fun;
Hou, Steven S.;
Perle, Stephen J.;
Le, Hoang;
Russ, Alyssa N.;
Lo, Eng H.;
Gerashchenko, Dmitry;
Gomperts, Stephen N.;
Bacskai, Brian J.;
Kastanenka, Ksenia V.

Publication type:

Article

Microglial function, INPP5D/SHIP1 signaling, and NLRP3 inflammasome activation: implications for Alzheimer's disease.

Published in:

Molecular Neurodegeneration, 2023, v. 18, n. 1, p. 1, doi. 10.1186/s13024-023-00674-9

By:

Terzioglu, Gizem;
Young-Pearse, Tracy L.

Publication type:

Article

Characterization of APOE Christchurch carriers in 455,306 UK Biobank participants.

Published in:

Molecular Neurodegeneration, 2023, v. 18, n. 1, p. 1, doi. 10.1186/s13024-023-00684-7

By:

He, Karen Y.;
Khramtsova, Ekaterina A.;
Cabrera-Socorro, Alfredo;
Zhang, Yanfei;
Li, Shuwei;
Sarver, Brice A. J.;
Smets, Bart;
Li, Qingqin S.;
De Muynck, Louis;
Parrado, Antonio R.;
Lovestone, Simon;
Black, Mary Helen

Publication type:

Article

Microglial function, INPP5D/SHIP1 signaling, and NLRP3 inflammasome activation: implications for Alzheimer's disease.

Published in:

Molecular Neurodegeneration, 2023, v. 18, n. 1, p. 1, doi. 10.1186/s13024-023-00674-9

By:

Terzioglu, Gizem;
Young-Pearse, Tracy L.

Publication type:

Article

Non-invasive systemic viral delivery of human alpha-synuclein mimics selective and progressive neuropathology of Parkinson's disease in rodent brains.

Published in:

Molecular Neurodegeneration, 2023, v. 18, n. 1, p. 1, doi. 10.1186/s13024-023-00683-8

By:

Bérard, Morgan;
Martínez-Drudis, Laura;
Sheta, Razan;
El-Agnaf, Omar M. A.;
Oueslati, Abid

Publication type:

Article

Alzheimer’s genes in microglia: a risk worth investigating.

Published in:

Molecular Neurodegeneration, 2023, v. 18, n. 1, p. 1, doi. 10.1186/s13024-023-00679-4

By:

Sudwarts, Ari;
Thinakaran, Gopal

Publication type:

Article

Donald Lowell Price, M.D. In memoriam.

Published in:

Molecular Neurodegeneration, 2023, v. 18, n. 1, p. 1, doi. 10.1186/s13024-023-00670-z

By:

Sisodia, Sangram;
Wong, Philip C.

Publication type:

Article

Multi-modal proteomic characterization of lysosomal function and proteostasis in progranulin-deficient neurons.

Published in:

Molecular Neurodegeneration, 2023, v. 18, n. 1, p. 1, doi. 10.1186/s13024-023-00673-w

By:

Hasan, Saadia;
Fernandopulle, Michael S.;
Humble, Stewart W.;
Frankenfield, Ashley M.;
Li, Haorong;
Prestil, Ryan;
Johnson, Kory R.;
Ryan, Brent J.;
Wade-Martins, Richard;
Ward, Michael E.;
Hao, Ling

Publication type:

Article

Roles of peripheral lipoproteins and cholesteryl ester transfer protein in the vascular contributions to cognitive impairment and dementia.

Published in:

Molecular Neurodegeneration, 2023, v. 18, n. 1, p. 1, doi. 10.1186/s13024-023-00671-y

By:

Poliakova, Tetiana;
Wellington, Cheryl L.

Publication type:

Article

Altered plasma protein profiles in genetic FTD – a GENFI study.

Published in:

Molecular Neurodegeneration, 2023, v. 18, n. 1, p. 1, doi. 10.1186/s13024-023-00677-6

By:

Ullgren, Abbe;
Öijerstedt, Linn;
Olofsson, Jennie;
Bergström, Sofia;
Remnestål, Julia;
van Swieten, John C.;
Jiskoot, Lize C.;
Seelaar, Harro;
Borroni, Barbara;
Sanchez-Valle, Raquel;
Moreno, Fermin;
Laforce, Robert;
Synofzik, Matthis;
Galimberti, Daniela;
Rowe, James B.;
Masellis, Mario;
Tartaglia, Maria Carmela;
Finger, Elizabeth;
Vandenberghe, Rik;
de Mendonça, Alexandre

Publication type:

Article

α-Synuclein serine129 phosphorylation – the physiology of pathology.

Published in:

2023

By:

Ramalingam, Nagendran;
Dettmer, Ulf

Publication type:

Editorial

Mitochondrial dysfunction in Parkinson's disease – a key disease hallmark with therapeutic potential.

Published in:

Molecular Neurodegeneration, 2023, v. 18, n. 1, p. 1, doi. 10.1186/s13024-023-00676-7

By:

Henrich, Martin T.;
Oertel, Wolfgang H.;
Surmeier, D. James;
Geibl, Fanni F.

Publication type:

Article

Simple model systems reveal conserved mechanisms of Alzheimer's disease and related tauopathies.

Published in:

Molecular Neurodegeneration, 2023, v. 18, n. 1, p. 1, doi. 10.1186/s13024-023-00664-x

By:

Jiang, Yuwei;
MacNeil, Lesley T.

Publication type:

Article

Correction: Drug development targeting degeneration of the basal forebrain cholinergic system: its time has come.

Published in:

2023

By:

Alam, John J.;
Nixon, Ralph A.

Publication type:

Correction Notice

Peptide-based approaches to directly target alpha-synuclein in Parkinson's disease.

Published in:

Molecular Neurodegeneration, 2023, v. 18, n. 1, p. 1, doi. 10.1186/s13024-023-00675-8

By:

Allen, Scott G.;
Meade, Richard M.;
White Stenner, Lucy L.;
Mason, Jody M.

Publication type:

Article

Mechanism and therapeutic potential of targeting cGAS-STING signaling in neurological disorders.

Published in:

Molecular Neurodegeneration, 2023, v. 18, n. 1, p. 1, doi. 10.1186/s13024-023-00672-x

By:

Huang, Yige;
Liu, Bangyan;
Sinha, Subhash C.;
Amin, Sadaf;
Gan, Li

Publication type:

Article

Genome-wide analyses identify NEAT1 as genetic modifier of age at onset of amyotrophic lateral sclerosis.

Published in:

Molecular Neurodegeneration, 2023, v. 18, n. 1, p. 1, doi. 10.1186/s13024-023-00669-6

By:

Li, Chunyu;
Wei, Qianqian;
Hou, Yanbing;
Lin, Junyu;
Ou, Ruwei;
Zhang, Lingyu;
Jiang, Qirui;
Xiao, Yi;
Liu, Kuncheng;
Chen, Xueping;
Yang, TianMi;
Song, Wei;
Zhao, Bi;
Wu, Ying;
Shang, Huifang

Publication type:

Article

cGAS-STING triggers inflammaging-associated neurodegeneration.

Published in:

Molecular Neurodegeneration, 2023, v. 18, n. 1, p. 1, doi. 10.1186/s13024-023-00666-9

By:

Izquierdo, José M.

Publication type:

Article

Mechanisms of ARIA: is it time to focus on the unique immune environment of the neurovascular unit?

Published in:

2023

By:

Foley, Kate E.;
Weekman, Erica M.;
Wilcock, Donna M.

Publication type:

Editorial

Regulation of cortical hyperexcitability in amyotrophic lateral sclerosis: focusing on glial mechanisms.

Published in:

Molecular Neurodegeneration, 2023, v. 18, n. 1, p. 1, doi. 10.1186/s13024-023-00665-w

By:

Xie, Manling;
Pallegar, Praveen N.;
Parusel, Sebastian;
Nguyen, Aivi T.;
Wu, Long-Jun

Publication type:

Article

Drug development targeting degeneration of the basal forebrain cholinergic system: its time has come.

Published in:

Molecular Neurodegeneration, 2023, v. 18, n. 1, p. 1, doi. 10.1186/s13024-023-00663-y

By:

Alam, John J.;
Nixon, Ralph A.

Publication type:

Article

Border-associated macrophages promote cerebral amyloid angiopathy and cognitive impairment through vascular oxidative stress.

Published in:

Molecular Neurodegeneration, 2023, v. 18, n. 1, p. 1, doi. 10.1186/s13024-023-00660-1

By:

Uekawa, Ken;
Hattori, Yorito;
Ahn, Sung Ji;
Seo, James;
Casey, Nicole;
Anfray, Antoine;
Zhou, Ping;
Luo, Wenjie;
Anrather, Josef;
Park, Laibaik;
Iadecola, Costantino

Publication type:

Article

Correction: Predominant expression of Alzheimer's disease-associated BIN1 in mature oligodendrocytes and localization to white matter tracts.

Published in:

2023

By:

De Rossi, Pierre;
Buggia-Prévot, Virginie;
Clayton, Benjamin L. L.;
Vasquez, Jared B.;
van Sanford, Carson;
Andrew, Robert J.;
Lesnick, Ruben;
Botté, Alexandra;
Deyts, Carole;
Salem, Someya;
Rao, Eshaan;
Rice, Richard C.;
Parent, Angèle;
Kar, Satyabrata;
Popko, Brian;
Pytel, Peter;
Estus, Steven;
Thinakaran, Gopal

Publication type:

Correction Notice

TDP-43 pathology is associated with increased tau burdens and seeding.

Published in:

Molecular Neurodegeneration, 2023, v. 18, n. 1, p. 1, doi. 10.1186/s13024-023-00653-0

By:

Tomé, Sandra O.;
Tsaka, Grigoria;
Ronisz, Alicja;
Ospitalieri, Simona;
Gawor, Klara;
Gomes, Luis Aragão;
Otto, Markus;
von Arnim, Christine A. F.;
Van Damme, Philip;
Van Den Bosch, Ludo;
Ghebremedhin, Estifanos;
Laureyssen, Celeste;
Sleegers, Kristel;
Vandenberghe, Rik;
Rousseau, Frederic;
Schymkowitz, Joost;
Thal, Dietmar Rudolf

Publication type:

Article

Correction: Targeted degradation of ⍺-synuclein aggregates in Parkinson's disease using the AUTOTAC technology.

Published in:

2023

By:

Lee, Jihoon;
Sung, Ki Woon;
Bae, Eun-Jin;
Yoon, Dabin;
Kim, Dasarang;
Lee, Jin Saem;
Park, Da-ha;
Park, Daniel Youngjae;
Mun, Su Ran;
Kwon, Soon Chul;
Kim, Hye Yeon;
Min, Joo-Ok;
Lee, Seung-Jae;
Suh, Young Ho;
Kwon, Yong Tae

Publication type:

Correction Notice

A microglial activity state biomarker panel differentiates FTD-granulin and Alzheimer's disease patients from controls.

Published in:

Molecular Neurodegeneration, 2023, v. 18, n. 1, p. 1, doi. 10.1186/s13024-023-00657-w

By:

Pesämaa, Ida;
Müller, Stephan A.;
Robinson, Sophie;
Darcher, Alana;
Paquet, Dominik;
Zetterberg, Henrik;
Lichtenthaler, Stefan F.;
Haass, Christian

Publication type:

Article

The Q/R editing site of AMPA receptor GluA2 subunit acts as an epigenetic switch regulating dendritic spines, neurodegeneration and cognitive deficits in Alzheimer's disease.

Published in:

Molecular Neurodegeneration, 2023, p. 1, doi. 10.1186/s13024-023-00632-5

By:

Wright, Amanda L.;
Konen, Lyndsey M.;
Mockett, Bruce G.;
Morris, Gary P.;
Singh, Anurag;
Burbano, Lisseth Estefania;
Milham, Luke;
Hoang, Monica;
Zinn, Raphael;
Chesworth, Rose;
Tan, Richard P.;
Royle, Gordon A.;
Clark, Ian;
Petrou, Steven;
Abraham, Wickliffe C.;
Vissel, Bryce

Publication type:

Article

Astrocytes of the optic nerve exhibit a region-specific and temporally distinct response to elevated intraocular pressure.

Published in:

Molecular Neurodegeneration, 2023, v. 18, n. 1, p. 1, doi. 10.1186/s13024-023-00658-9

By:

Mazumder, Arpan G.;
Julé, Amélie M.;
Sun, Daniel

Publication type:

Article

BAX activation in mouse retinal ganglion cells occurs in two temporally and mechanistically distinct steps.

Published in:

Molecular Neurodegeneration, 2023, v. 18, n. 1, p. 1, doi. 10.1186/s13024-023-00659-8

By:

Maes, Margaret E.;
Donahue, Ryan J.;
Schlamp, Cassandra L.;
Marola, Olivia J.;
Libby, Richard T.;
Nickells, Robert W.

Publication type:

Article

News & views: anti-amyloid antibodies and novel emerging approaches to Alzheimer's disease in 2023.

Published in:

Molecular Neurodegeneration, 2023, v. 18, n. 1, p. 1, doi. 10.1186/s13024-023-00656-x

By:

Gandy, Sam

Publication type:

Article

Retinal ganglion cell repopulation for vision restoration in optic neuropathy: a roadmap from the RReSTORe Consortium.

Published in:

Molecular Neurodegeneration, 2023, v. 18, n. 1, p. 1, doi. 10.1186/s13024-023-00655-y

By:

Soucy, Jonathan R.;
Aguzzi, Erika A.;
Cho, Julie;
Gilhooley, Michael James;
Keuthan, Casey;
Luo, Ziming;
Monavarfeshani, Aboozar;
Saleem, Meher A.;
Wang, Xue-Wei;
Wohlschlegel, Juilette;
Fouda, Abdelrahman Y.;
Ashok, Ajay;
Moshiri, Ala;
Chedotal, Alain;
Reed, Amberlynn A.;
Askary, Amjad;
Su, An-Jey A.;
La Torre, Anna;
Jalligampala, Archana;
Silva-Lepe, Ariadna

Publication type:

Article

Regulation of the hippocampal translatome by Apoer2-ICD release.

Published in:

Molecular Neurodegeneration, 2023, v. 18, n. 1, p. 1, doi. 10.1186/s13024-023-00652-1

By:

Wasser, Catherine R.;
Werthmann, Gordon C.;
Hall, Eric M.;
Kuhbandner, Kristina;
Wong, Connie H.;
Durakoglugil, Murat S.;
Herz, Joachim

Publication type:

Article

The major TMEM106B dementia risk allele affects TMEM106B protein levels, fibril formation, and myelin lipid homeostasis in the ageing human hippocampus.

Published in:

Molecular Neurodegeneration, 2023, v. 18, n. 1, p. 1, doi. 10.1186/s13024-023-00650-3

By:

Lee, Jun Yup;
Harney, Dylan J;
Teo, Jonathan D;
Kwok, John B;
Sutherland, Greg T.;
Larance, Mark;
Don, Anthony S

Publication type:

Article

Amyloid fibril proteomics of AD brains reveals modifiers of aggregation and toxicity.

Published in:

Molecular Neurodegeneration, 2023, v. 18, n. 1, p. 1, doi. 10.1186/s13024-023-00654-z

By:

Upadhyay, Arun;
Chhangani, Deepak;
Rao, Nalini R.;
Kofler, Julia;
Vassar, Robert;
Rincon-Limas, Diego E.;
Savas, Jeffrey N.

Publication type:

Article

Tracking reactive astrogliosis in autosomal dominant and sporadic Alzheimer's disease with multi-modal PET and plasma GFAP.

Published in:

Molecular Neurodegeneration, 2023, v. 18, n. 1, p. 1, doi. 10.1186/s13024-023-00647-y

By:

Chiotis, Konstantinos;
Johansson, Charlotte;
Rodriguez-Vieitez, Elena;
Ashton, Nicholas J.;
Blennow, Kaj;
Zetterberg, Henrik;
Graff, Caroline;
Nordberg, Agneta

Publication type:

Article

Amyloid-β (Aβ) immunotherapy induced microhemorrhages are associated with activated perivascular macrophages and peripheral monocyte recruitment in Alzheimer's disease mice.

Published in:

Molecular Neurodegeneration, 2023, v. 18, n. 1, p. 1, doi. 10.1186/s13024-023-00649-w

By:

Taylor, Xavier;
Clark, Isaiah M.;
Fitzgerald, Griffin J.;
Oluoch, Herold;
Hole, Justin T.;
DeMattos, Ronald B.;
Wang, Yaming;
Pan, Feng

Publication type:

Article

Translation dysregulation in neurodegenerative diseases: a focus on ALS.

Published in:

Molecular Neurodegeneration, 2023, v. 18, n. 1, p. 1, doi. 10.1186/s13024-023-00642-3

By:

Wang, Shaopeng;
Sun, Shuying

Publication type:

Article

TDP-43-regulated cryptic RNAs accumulate in Alzheimer's disease brains.

Published in:

Molecular Neurodegeneration, 2023, v. 18, n. 1, p. 1, doi. 10.1186/s13024-023-00646-z

By:

Estades Ayuso, Virginia;
Pickles, Sarah;
Todd, Tiffany;
Yue, Mei;
Jansen-West, Karen;
Song, Yuping;
González Bejarano, Jesús;
Rawlinson, Bailey;
DeTure, Michael;
Graff-Radford, Neill R.;
Boeve, Bradley F.;
Knopman, David S.;
Petersen, Ronald C.;
Dickson, Dennis W.;
Josephs, Keith A.;
Petrucelli, Leonard;
Prudencio, Mercedes

Publication type:

Article

Current views on meningeal lymphatics and immunity in aging and Alzheimer's disease.

Published in:

Molecular Neurodegeneration, 2023, v. 18, n. 1, p. 1, doi. 10.1186/s13024-023-00645-0

By:

Rego, Shanon;
Sanchez, Guadalupe;
Da Mesquita, Sandro

Publication type:

Article

Oleoylethanolamide facilitates PPARα and TFEB signaling and attenuates Aβ pathology in a mouse model of Alzheimer's disease.

Published in:

Molecular Neurodegeneration, 2023, v. 18, p. 1, doi. 10.1186/s13024-023-00648-x

By:

Comerota, Michele M.;
Gedam, Manasee;
Xiong, Wen;
Jin, Feng;
Deng, Lisheng;
Wang, Meng C.;
Wang, Jin;
Zheng, Hui

Publication type:

Article

TMEM106B aggregation in neurodegenerative diseases: linking genetics to function.

Published in:

Molecular Neurodegeneration, 2023, v. 18, n. 1, p. 1, doi. 10.1186/s13024-023-00644-1

By:

Jiao, Hai-Shan;
Yuan, Peng;
Yu, Jin-Tai

Publication type:

Article

Specific detection of tau seeding activity in Alzheimer's disease using rationally designed biosensor cells.

Published in:

Molecular Neurodegeneration, 2023, v. 18, n. 1, p. 1, doi. 10.1186/s13024-023-00643-2

By:

Lathuiliere, Aurelien;
Jo, Youhwa;
Perbet, Romain;
Donahue, Cameron;
Commins, Caitlin;
Quittot, Noé;
Fan, Zhanyun;
Bennett, Rachel E.;
Hyman, Bradley T.

Publication type:

Article

Valosin containing protein (VCP): initiator, modifier, and potential drug target for neurodegenerative diseases.

Published in:

Molecular Neurodegeneration, 2023, v. 18, n. 1, p. 1, doi. 10.1186/s13024-023-00639-y

By:

Chu, Siwei;
Xie, Xinyi;
Payan, Carla;
Stochaj, Ursula

Publication type:

Article

VPS35 and α-Synuclein fail to interact to modulate neurodegeneration in rodent models of Parkinson's disease.

Published in:

Molecular Neurodegeneration, 2023, v. 18, n. 1, p. 1, doi. 10.1186/s13024-023-00641-4

By:

Chen, Xi;
Tsika, Elpida;
Levine, Nathan;
Moore, Darren J.

Publication type:

Article