Works matching IS 17501326 AND DT 2018 AND VI 13 AND IP 1
Results: 53
Proteolytic cleavage of Beclin 1 exacerbates neurodegeneration.
- Published in:
- Molecular Neurodegeneration, 2018, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13024-018-0302-4
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- Publication type:
- Article
Development and validation of a simplified method to generate human microglia from pluripotent stem cells.
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- Molecular Neurodegeneration, 2018, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13024-018-0297-x
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- Publication type:
- Article
The Trem2 R47H Alzheimer’s risk variant impairs splicing and reduces Trem2 mRNA and protein in mice but not in humans.
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- Molecular Neurodegeneration, 2018, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13024-018-0280-6
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- Publication type:
- Article
New insights into the role of TREM2 in Alzheimer's disease.
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- Molecular Neurodegeneration, 2018, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13024-018-0298-9
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- Article
Advances in developing novel therapeutic strategies for Alzheimer's disease.
- Published in:
- Molecular Neurodegeneration, 2018, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13024-018-0299-8
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- Publication type:
- Article
Correction to: Peripheral immune system in aging and Alzheimer's disease.
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- 2018
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- Publication type:
- Correction Notice
GSK3β-mediated tau hyperphosphorylation triggers diabetic retinal neurodegeneration by disrupting synaptic and mitochondrial functions.
- Published in:
- Molecular Neurodegeneration, 2018, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13024-018-0295-z
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- Publication type:
- Article
Functional alterations of myeloid cells during the course of Alzheimer's disease.
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- Molecular Neurodegeneration, 2018, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13024-018-0293-1
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- Publication type:
- Article
Genome-wide RNAseq study of the molecular mechanisms underlying microglia activation in response to pathological tau perturbation in the rTg4510 tau transgenic animal model.
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- Molecular Neurodegeneration, 2018, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13024-018-0296-y
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- Publication type:
- Article
Tissue-enhanced plasma proteomic analysis for disease stratification in amyotrophic lateral sclerosis.
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- Molecular Neurodegeneration, 2018, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13024-018-0292-2
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- Article
Disease-modifying effects of metabolic perturbations in ALS/FTLD.
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- Molecular Neurodegeneration, 2018, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13024-018-0294-0
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- Publication type:
- Article
Blood-brain barrier-associated pericytes internalize and clear aggregated amyloid-β42 by LRP1-dependent apolipoprotein E isoform-specific mechanism.
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- Molecular Neurodegeneration, 2018, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13024-018-0286-0
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- Publication type:
- Article
Essential roles of mitochondrial biogenesis regulator Nrf1 in retinal development and homeostasis.
- Published in:
- Molecular Neurodegeneration, 2018, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13024-018-0287-z
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- Publication type:
- Article
Peripheral immune system in aging and Alzheimer's disease.
- Published in:
- Molecular Neurodegeneration, 2018, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13024-018-0284-2
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- Publication type:
- Article
A brain-penetrant triazolopyrimidine enhances microtubule-stability, reduces axonal dysfunction and decreases tau pathology in a mouse tauopathy model.
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- Molecular Neurodegeneration, 2018, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13024-018-0291-3
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- Publication type:
- Article
Progranulin reduces insoluble TDP-43 levels, slows down axonal degeneration and prolongs survival in mutant TDP-43 mice.
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- Molecular Neurodegeneration, 2018, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13024-018-0288-y
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- Publication type:
- Article
Deep proteomic network analysis of Alzheimer's disease brain reveals alterations in RNA binding proteins and RNA splicing associated with disease.
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- Molecular Neurodegeneration, 2018, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13024-018-0282-4
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- Publication type:
- Article
Modifying Rap1-signalling by targeting Pde6δ is neuroprotective in models of Alzheimer's disease.
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- Molecular Neurodegeneration, 2018, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13024-018-0283-3
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- Publication type:
- Article
ABI3 and PLCG2 missense variants as risk factors for neurodegenerative diseases in Caucasians and African Americans.
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- Molecular Neurodegeneration, 2018, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13024-018-0289-x
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- Publication type:
- Article
Deregulation of neuronal miRNAs induced by amyloid-β or TAU pathology.
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- Molecular Neurodegeneration, 2018, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13024-018-0285-1
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- Publication type:
- Article
Early lysosomal maturation deficits in microglia triggers enhanced lysosomal activity in other brain cells of progranulin knockout mice.
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- Molecular Neurodegeneration, 2018, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13024-018-0281-5
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- Publication type:
- Article
Alzheimer-associated cerebrospinal fluid fragments of neurogranin are generated by Calpain-1 and prolyl endopeptidase.
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- Molecular Neurodegeneration, 2018, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13024-018-0279-z
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- Publication type:
- Article
Long-read sequencing across the C9orf72 ‘GGGGCC’ repeat expansion: implications for clinical use and genetic discovery efforts in human disease.
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- Molecular Neurodegeneration, 2018, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13024-018-0274-4
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- Publication type:
- Article
Subretinal macrophages produce classical complement activator C1q leading to the progression of focal retinal degeneration.
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- Molecular Neurodegeneration, 2018, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13024-018-0278-0
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- Publication type:
- Article
2D versus 3D human induced pluripotent stem cell-derived cultures for neurodegenerative disease modelling.
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- Molecular Neurodegeneration, 2018, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13024-018-0258-4
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- Publication type:
- Article
Large-scale transcriptomic analysis reveals that pridopidine reverses aberrant gene expression and activates neuroprotective pathways in the YAC128 HD mouse.
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- Molecular Neurodegeneration, 2018, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13024-018-0259-3
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- Publication type:
- Article
Tolerogenic bone marrow-derived dendritic cells induce neuroprotective regulatory T cells in a model of Parkinson's disease.
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- Molecular Neurodegeneration, 2018, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13024-018-0255-7
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- Publication type:
- Article
Vibrational spectroscopy: a promising approach to discriminate neurodegenerative disorders.
- Published in:
- 2018
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- Publication type:
- Letter
PU.1 regulates Alzheimer’s disease-associated genes in primary human microglia.
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- Molecular Neurodegeneration, 2018, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13024-018-0277-1
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- Publication type:
- Article
Immunotherapy targeting toll-like receptor 2 alleviates neurodegeneration in models of synucleinopathy by modulating α-synuclein transmission and neuroinflammation.
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- Molecular Neurodegeneration, 2018, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13024-018-0276-2
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- Publication type:
- Article
Differential induction of mutant SOD1 misfolding and aggregation by tau and α-synuclein pathology.
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- Molecular Neurodegeneration, 2018, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13024-018-0253-9
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- Publication type:
- Article
Counteracting roles of MHCI and CD8<sup>+</sup> T cells in the peripheral and central nervous system of ALS SOD1<sup>G93A</sup> mice.
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- Molecular Neurodegeneration, 2018, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13024-018-0271-7
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- Publication type:
- Article
Joint genome-wide association study of progressive supranuclear palsy identifies novel susceptibility loci and genetic correlation to neurodegenerative diseases.
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- Molecular Neurodegeneration, 2018, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13024-018-0270-8
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- Publication type:
- Article
A new hypothesis for Parkinson’s disease pathogenesis: GTPase-p38 MAPK signaling and autophagy as convergence points of etiology and genomics.
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- Molecular Neurodegeneration, 2018, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13024-018-0273-5
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- Publication type:
- Article
Transcriptional profiling of HERV-K(HML-2) in amyotrophic lateral sclerosis and potential implications for expression of HML-2 proteins.
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- Molecular Neurodegeneration, 2018, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13024-018-0275-3
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- Publication type:
- Article
Polygenic analysis of inflammatory disease variants and effects on microglia in the aging brain.
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- Molecular Neurodegeneration, 2018, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13024-018-0272-6
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- Publication type:
- Article
Replication of progressive supranuclear palsy genome-wide association study identifies <italic>SLCO1A2</italic> and <italic>DUSP10</italic> as new susceptibility loci.
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- Molecular Neurodegeneration, 2018, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13024-018-0267-3
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- Publication type:
- Article
Clinical spectrum and genetic landscape for hereditary spastic paraplegias in China.
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- Molecular Neurodegeneration, 2018, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13024-018-0269-1
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- Publication type:
- Article
<italic>TMEM106B</italic> haplotypes have distinct gene expression patterns in aged brain.
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- Molecular Neurodegeneration, 2018, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13024-018-0268-2
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- Publication type:
- Article
Quantitative proteomics of acutely-isolated mouse microglia identifies novel immune Alzheimer's disease-related proteins.
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- Molecular Neurodegeneration, 2018, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13024-018-0266-4
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- Publication type:
- Article
iPSC-derived familial Alzheimer's <italic>PSEN2</italic><sup><italic>N141I</italic></sup> cholinergic neurons exhibit mutation-dependent molecular pathology corrected by insulin signaling.
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- Molecular Neurodegeneration, 2018, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13024-018-0265-5
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- Publication type:
- Article
Partial Tmem106b reduction does not correct abnormalities due to progranulin haploinsufficiency.
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- Molecular Neurodegeneration, 2018, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13024-018-0264-6
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- Publication type:
- Article
Transcriptional profiling and biomarker identification reveal tissue specific effects of expanded ataxin-3 in a spinocerebellar ataxia type 3 mouse model.
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- Molecular Neurodegeneration, 2018, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13024-018-0261-9
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- Publication type:
- Article
Protective paraspeckle hyper-assembly downstream of TDP-43 loss of function in amyotrophic lateral sclerosis.
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- Molecular Neurodegeneration, 2018, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13024-018-0263-7
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- Publication type:
- Article
The <italic>T</italic>rem<italic>2</italic> R47H variant confers loss-of-function-like phenotypes in Alzheimer's disease.
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- Molecular Neurodegeneration, 2018, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13024-018-0262-8
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- Publication type:
- Article
Targeting energy metabolism via the mitochondrial pyruvate carrier as a novel approach to attenuate neurodegeneration.
- Published in:
- Molecular Neurodegeneration, 2018, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13024-018-0260-x
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- Publication type:
- Article
AMPA-ergic regulation of amyloid-β levels in an Alzheimer's disease mouse model.
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- Molecular Neurodegeneration, 2018, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13024-018-0256-6
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- Publication type:
- Article
Inoculation of α-synuclein preformed fibrils into the mouse gastrointestinal tract induces Lewy body-like aggregates in the brainstem via the vagus nerve.
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- Molecular Neurodegeneration, 2018, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13024-018-0257-5
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- Publication type:
- Article
Identification and therapeutic modulation of a pro-inflammatory subset of disease-associated-microglia in Alzheimer's disease.
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- Molecular Neurodegeneration, 2018, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13024-018-0254-8
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- Publication type:
- Article
Modulation of GSK-3 provides cellular and functional neuroprotection in the <italic>rd10</italic> mouse model of retinitis pigmentosa.
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- Molecular Neurodegeneration, 2018, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13024-018-0251-y
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- Publication type:
- Article