Works matching IS 17501326 AND DT 2018 AND VI 13 AND IP 1

Results: 53
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    Genome-wide RNAseq study of the molecular mechanisms underlying microglia activation in response to pathological tau perturbation in the rTg4510 tau transgenic animal model.

    Published in:
    Molecular Neurodegeneration, 2018, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13024-018-0296-y
    By:
    • Wang, Hong;
    • Li, Yupeng;
    • Ryder, John W.;
    • Hole, Justin T.;
    • Ebert, Philip J.;
    • Airey, David C.;
    • Qian, Hui-Rong;
    • Logsdon, Benjamin;
    • Fisher, Alice;
    • Ahmed, Zeshan;
    • Murray, Tracey K.;
    • Cavallini, Annalisa;
    • Bose, Suchira;
    • Eastwood, Brian J.;
    • Collier, David A.;
    • Dage, Jeffrey L.;
    • Miller, Bradley B.;
    • Merchant, Kalpana M.;
    • O'Neill, Michael J.;
    • Demattos, Ronald B.
    Publication type:
    Article
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    Deregulation of neuronal miRNAs induced by amyloid-β or TAU pathology.

    Published in:
    Molecular Neurodegeneration, 2018, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13024-018-0285-1
    By:
    • Sierksma, Annerieke;
    • Lu, Ashley;
    • Salta, Evgenia;
    • Vanden Eynden, Elke;
    • Callaerts-Vegh, Zsuzsanna;
    • D'Hooge, Rudi;
    • Blum, David;
    • Buée, Luc;
    • Fiers, Mark;
    • De Strooper, Bart
    Publication type:
    Article
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    ABI3 and PLCG2 missense variants as risk factors for neurodegenerative diseases in Caucasians and African Americans.

    Published in:
    Molecular Neurodegeneration, 2018, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13024-018-0289-x
    By:
    • Conway, Olivia J;
    • Carrasquillo, Minerva M;
    • Wang, Xue;
    • Bredenberg, Jenny M;
    • Reddy, Joseph S;
    • Strickland, Samantha L;
    • Younkin, Curtis S;
    • Burgess, Jeremy D;
    • Allen, Mariet;
    • Lincoln, Sarah J;
    • Nguyen, Thuy;
    • Malphrus, Kimberly G;
    • Soto, Alexandra I;
    • Walton, Ronald L;
    • Boeve, Bradley F;
    • Petersen, Ronald C;
    • Lucas, John A;
    • Ferman, Tanis J;
    • Cheshire, William P;
    • van Gerpen, Jay A
    Publication type:
    Article
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    Modifying Rap1-signalling by targeting Pde6δ is neuroprotective in models of Alzheimer's disease.

    Published in:
    Molecular Neurodegeneration, 2018, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13024-018-0283-3
    By:
    • Van Dooren, Tom;
    • Princen, Katrien;
    • De Witte, Koen;
    • Griffioen, Gerard;
    • Dumbacher, Michael;
    • Hoogenraad, Casper C.;
    • Farinelli, Mélissa;
    • Lievens, Sam;
    • Tavernier, Jan;
    • Dehaen, Wim;
    • Wera, Stefaan;
    • Winderickx, Joris;
    • Allasia, Sara;
    • Kilonda, Amuri;
    • Spieser, Stéphane;
    • Marchand, Arnaud;
    • Chaltin, Patrick
    Publication type:
    Article
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    Long-read sequencing across the C9orf72 ‘GGGGCC’ repeat expansion: implications for clinical use and genetic discovery efforts in human disease.

    Published in:
    Molecular Neurodegeneration, 2018, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13024-018-0274-4
    By:
    • Ebbert, Mark T. W.;
    • Farrugia, Stefan L.;
    • Sens, Jonathon P.;
    • Jansen-West, Karen;
    • Gendron, Tania F.;
    • Prudencio, Mercedes;
    • McLaughlin, Ian J.;
    • Bowman, Brett;
    • Seetin, Matthew;
    • DeJesus-Hernandez, Mariely;
    • Jackson, Jazmyne;
    • Brown, Patricia H.;
    • Dickson, Dennis W.;
    • van Blitterswijk, Marka;
    • Rademakers, Rosa;
    • Petrucelli, Leonard;
    • Fryer, John D.
    Publication type:
    Article
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    PU.1 regulates Alzheimer’s disease-associated genes in primary human microglia.

    Published in:
    Molecular Neurodegeneration, 2018, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13024-018-0277-1
    By:
    • Rustenhoven, Justin;
    • Smith, Amy M.;
    • Smyth, Leon C.;
    • Jansson, Deidre;
    • Scotter, Emma L.;
    • Swanson, Molly E. V.;
    • Aalderink, Miranda;
    • Coppieters, Natacha;
    • Narayan, Pritika;
    • Handley, Renee;
    • Overall, Chris;
    • Park, Thomas I. H.;
    • Schweder, Patrick;
    • Heppner, Peter;
    • Curtis, Maurice A.;
    • Faull, Richard L. M.;
    • Dragunow, Mike
    Publication type:
    Article
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    Replication of progressive supranuclear palsy genome-wide association study identifies <italic>SLCO1A2</italic> and <italic>DUSP10</italic> as new susceptibility loci.

    Published in:
    Molecular Neurodegeneration, 2018, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13024-018-0267-3
    By:
    • Sanchez-Contreras, Monica Y.;
    • Kouri, Naomi;
    • Cook, Casey N.;
    • Serie, Daniel J.;
    • Heckman, Michael G.;
    • Finch, NiCole A.;
    • Caselli, Richard J.;
    • Uitti, Ryan J.;
    • Wszolek, Zbigniew K.;
    • Graff-Radford, Neill;
    • Petrucelli, Leonard;
    • Wang, Li-San;
    • Schellenberg, Gerard D.;
    • Dickson, Dennis W.;
    • Rademakers, Rosa;
    • Ross, Owen A.
    Publication type:
    Article
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    Joint genome-wide association study of progressive supranuclear palsy identifies novel susceptibility loci and genetic correlation to neurodegenerative diseases.

    Published in:
    Molecular Neurodegeneration, 2018, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13024-018-0270-8
    By:
    • Chen, Jason A.;
    • Chen, Zhongbo;
    • Won, Hyejung;
    • Huang, Alden Y.;
    • Lowe, Jennifer K.;
    • Wojta, Kevin;
    • Yokoyama, Jennifer S.;
    • Bensimon, Gilbert;
    • Leigh, P. Nigel;
    • Payan, Christine;
    • Shatunov, Aleksey;
    • Jones, Ashley R.;
    • Lewis, Cathryn M.;
    • Deloukas, Panagiotis;
    • Amouyel, Philippe;
    • Tzourio, Christophe;
    • Dartigues, Jean-Francois;
    • Ludolph, Albert;
    • Boxer, Adam L.;
    • Bronstein, Jeff M.
    Publication type:
    Article
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    Immunotherapy targeting toll-like receptor 2 alleviates neurodegeneration in models of synucleinopathy by modulating α-synuclein transmission and neuroinflammation.

    Published in:
    Molecular Neurodegeneration, 2018, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13024-018-0276-2
    By:
    • Kim, Changyoun;
    • Spencer, Brian;
    • Rockenstein, Edward;
    • Yamakado, Hodaka;
    • Mante, Michael;
    • Adame, Anthony;
    • Fields, Jerel Adam;
    • Masliah, Deborah;
    • Iba, Michiyo;
    • Lee, He-Jin;
    • Rissman, Robert A.;
    • Lee, Seung-Jae;
    • Masliah, Eliezer
    Publication type:
    Article
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    iPSC-derived familial Alzheimer's <italic>PSEN2</italic><sup><italic>N141I</italic></sup> cholinergic neurons exhibit mutation-dependent molecular pathology corrected by insulin signaling.

    Published in:
    Molecular Neurodegeneration, 2018, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13024-018-0265-5
    By:
    • Moreno, Cesar L.;
    • Guardia, Lucio Della;
    • Shnyder, Valeria;
    • Ortiz-Virumbrales, Maitane;
    • Kruglikov, Ilya;
    • Zhang, Bin;
    • Schadt, Eric E.;
    • Tanzi, Rudolph E.;
    • Noggle, Scott;
    • Buettner, Christoph;
    • Gandy, Sam
    Publication type:
    Article
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    Transcriptional profiling and biomarker identification reveal tissue specific effects of expanded ataxin-3 in a spinocerebellar ataxia type 3 mouse model.

    Published in:
    Molecular Neurodegeneration, 2018, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13024-018-0261-9
    By:
    • Toonen, Lodewijk J. A.;
    • Overzier, Maurice;
    • Evers, Melvin M.;
    • Leon, Leticia G.;
    • van der Zeeuw, Sander A. J.;
    • Mei, Hailiang;
    • Kielbasa, Szymon M.;
    • Goeman, Jelle J.;
    • Hettne, Kristina M.;
    • Magnusson, Olafur Th.;
    • Poirel, Marion;
    • Seyer, Alexandre;
    • 't Hoen, Peter A. C.;
    • van Roon-Mom, Willeke M. C.
    Publication type:
    Article
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    The <italic>T</italic>rem<italic>2</italic> R47H variant confers loss-of-function-like phenotypes in Alzheimer's disease.

    Published in:
    Molecular Neurodegeneration, 2018, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13024-018-0262-8
    By:
    • Cheng-Hathaway, Paul J.;
    • Reed-Geaghan, Erin G.;
    • Jay, Taylor R.;
    • Casali, Brad T.;
    • Bemiller, Shane M.;
    • Puntambekar, Shweta S.;
    • von Saucken, Victoria E.;
    • Williams, Roxanne Y.;
    • Karlo, J. Colleen;
    • Moutinho, Miguel;
    • Xu, Guixiang;
    • Ransohoff, Richard M.;
    • Lamb, Bruce T.;
    • Landreth, Gary E.
    Publication type:
    Article
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    Large-scale transcriptomic analysis reveals that pridopidine reverses aberrant gene expression and activates neuroprotective pathways in the YAC128 HD mouse.

    Published in:
    Molecular Neurodegeneration, 2018, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13024-018-0259-3
    By:
    • Kusko, Rebecca;
    • Dreymann, Jennifer;
    • Ross, Jermaine;
    • Cha, Yoonjeong;
    • Escalante-Chong, Renan;
    • Garcia-Miralles, Marta;
    • Tan, Liang Juin;
    • Burczynski, Michael E.;
    • Zeskind, Ben;
    • Laifenfeld, Daphna;
    • Pouladi, Mahmoud;
    • Geva, Michal;
    • Grossman, Iris;
    • Hayden, Michael R.
    Publication type:
    Article
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