Works matching IS 17501326 AND DT 2016 AND VI 11

Results: 75

ULK1-mediated phosphorylation of ATG14 promotes autophagy and is impaired in Huntington's disease models.

Published in:

Molecular Neurodegeneration, 2016, v. 11, p. 1, doi. 10.1186/s13024-016-0141-0

By:

Wold, Mitchell S.;
Lim, Junghyun;
Lachance, Véronik;
Zhiqiang Deng;
Zhenyu Yue

Publication type:

Article

3D culture models of Alzheimer's disease: a road map to a "cure-in-a-dish".

Published in:

Molecular Neurodegeneration, 2016, v. 11, p. 1, doi. 10.1186/s13024-016-0139-7

By:

Se Hoon Choi;
Young Hye Kim;
Quinti, Luisa;
Tanzi, Rudolph E.;
Doo Yeon Kim

Publication type:

Article

Glymphatic distribution of CSF-derived apoE into brain is isoform specific and suppressed during sleep deprivation.

Published in:

Molecular Neurodegeneration, 2016, v. 11, p. 1, doi. 10.1186/s13024-016-0138-8

By:

Achariyar, Thiyagaragan M.;
Baoman Li;
Weiguo Peng;
Verghese, Philip B.;
Yang Shi;
McConnell, Evan;
Benraiss, Abdellatif;
Kasper, Tristan;
Wei Song;
Takahiro Takana;
Holtzman, David M.;
Nedergaard, Maiken;
Deane, Rashid

Publication type:

Article

LRRK2 at the interface of autophagosomes, endosomes and lysosomes.

Published in:

Molecular Neurodegeneration, 2016, v. 11, p. 1, doi. 10.1186/s13024-016-0140-1

By:

Roosen, Dorien A.;
Cookson, Mark R.

Publication type:

Article

Cerebrospinal fluid Presenilin-1 increases at asymptomatic stage in genetically determined Alzheimer's disease.

Published in:

Molecular Neurodegeneration, 2016, v. 11, p. 1, doi. 10.1186/s13024-016-0131-2

By:

Sogorb-Esteve, Aitana;
Sánchez-Valle, Raquel;
Lleó, Alberto;
Molinuevo, José-Luis;
Sáez-Valero, Javier;
Fortea, Juan

Publication type:

Article

Expression and processing analyses of wild type and p.R47H TREM2 variant in Alzheimer's disease brains.

Published in:

Molecular Neurodegeneration, 2016, v. 11, p. 1, doi. 10.1186/s13024-016-0137-9

By:

Ma, Li;
Allen, Mariet;
Sakae, Nobutaka;
Ertekin-Taner, Nilufer;
Graff-Radford, Neill R.;
Dickson, Dennis W.;
Younkin, Steven G.;
Sevlever, Daniel

Publication type:

Article

Role of cytochrome c in ɑ-synuclein radical formation: implications of ɑ-synuclein in neuronal death in Maneb- and paraquat-induced model of Parkinson's disease.

Published in:

Molecular Neurodegeneration, 2016, v. 11, p. 1, doi. 10.1186/s13024-016-0135-y

By:

Kumar, Ashutosh;
Ganini, Douglas;
Mason, Ronald P.

Publication type:

Article

Progranulin promotes peripheral nerve regeneration and reinnervation: role of notch signaling.

Published in:

Molecular Neurodegeneration, 2016, v. 11, p. 1, doi. 10.1186/s13024-016-0132-1

By:

Altmann, Christine;
Vasic, Verica;
Hardt, Stefanie;
Heidler, Juliana;
Häussler, Annett;
Wittig, Ilka;
Schmidt, Mirko H. H.;
Tegeder, Irmgard

Publication type:

Article

Spinal cord injury induces astroglial conversion towards neuronal lineage.

Published in:

Molecular Neurodegeneration, 2016, v. 11, p. 1, doi. 10.1186/s13024-016-0133-0

By:

Noristani, Harun Najib;
Sabourin, Jean Charles;
Boukhaddaoui, Hassan;
Chan-Seng, Emilie;
Gerber, Yannick Nicolas;
Perrin, Florence Evelyne

Publication type:

Article

Seizure protein 6 and its homolog seizure 6-like protein are physiological substrates of BACE1 in neurons.

Published in:

Molecular Neurodegeneration, 2016, v. 11, p. 1, doi. 10.1186/s13024-016-0134-z

By:

Pigoni, Martina;
Wanngren, Johanna;
Kuhn, Peer-Hendrik;
Munro, Kathryn M.;
Gunnersen, Jenny M.;
Takeshima, Hiroshi;
Feederle, Regina;
Voytyuk, Iryna;
De Strooper, Bart;
Levasseur, Mikail D.;
Hrupka, Brian J.;
Müller, Stephan A.;
Lichtenthaler, Stefan F.

Publication type:

Article

Chronic adiponectin deficiency leads to Alzheimer's disease-like cognitive impairments and pathologies through AMPK inactivation and cerebral insulin resistance in aged mice.

Published in:

Molecular Neurodegeneration, 2016, v. 11, p. 1, doi. 10.1186/s13024-016-0136-x

By:

Chun-Laam Ng, Roy;
On-Yin Cheng;
Min Jian;
Shing-Cheong Kwan, Jason;
Wing-Lok Ho, Philip;
King-Yip Cheng, Kenneth;
Ka Kit Yeung, Patrick;
Lei Zhou, Lena;
Lai-Chong Hoo, Ruby;
Kim Chung, Sookja;
Aimin Xu;
Siu-Ling Lam, Karen;
Ho Chan, Koon

Publication type:

Article

Predominant expression of Alzheimer's disease-associated BIN1 in mature oligodendrocytes and localization to white matter tracts.

Published in:

Molecular Neurodegeneration, 2016, v. 11, p. 1, doi. 10.1186/s13024-016-0124-1

By:

De Rossi, Pierre;
Buggia-Prévot, Virginie;
Clayton, Benjamin L. L.;
Vasquez, Jared B.;
van Sanford, Carson;
Andrew, Robert J.;
Lesnick, Ruben;
Botté, Alexandra;
Deyts, Carole;
Salem, Someya;
Rao, Eshaan;
Rice, Richard C.;
Parent, Angèle;
Kar, Satyabrata;
Popko, Brian;
Pytel, Peter;
Estus, Steven;
Thinakaran, Gopal

Publication type:

Article

No diurnal variation of classical and candidate biomarkers of Alzheimer's disease in CSF.

Published in:

Molecular Neurodegeneration, 2016, v. 11, p. 1, doi. 10.1186/s13024-016-0130-3

By:

Cicognola, Claudia;
Chiasserini, Davide;
Eusebi, Paolo;
Andreasson, Ulf;
Vanderstichele, Hugo;
Zetterberg, Henrik;
Parnetti, Lucilla;
Blennow, Kaj

Publication type:

Article

A Christianson syndrome-linked deletion mutation (Δ287 ES288) in SLC9A6 disrupts recycling endosomal function and elicits neurodegeneration and cell death.

Published in:

Molecular Neurodegeneration, 2016, v. 11, p. 1, doi. 10.1186/s13024-016-0129-9

By:

Ilie, Alina;
Gao, Andy Y. L.;
Reid, Jonathan;
Boucher, Annie;
McEwan, Cassandra;
Barrière, Hervé;
Lukacs, Gergely L.;
McKinney, R. Anne;
Orlowski, John

Publication type:

Article

Affinity of Tau antibodies for solubilized pathological Tau species but not their immunogen or insoluble Tau aggregates predicts in vivo and ex vivo efficacy.

Published in:

Molecular Neurodegeneration, 2016, v. 11, p. 1, doi. 10.1186/s13024-016-0126-z

By:

Congdon, Erin E.;
Yan Lin;
Rajamohamedsait, Hameetha B.;
Shamir, Dov B.;
Krishnaswamy, Senthilkumar;
Rajamohamedsait, Wajitha J.;
Rasool, Suhail;
Gonzalez, Veronica;
Levenga, Josien;
Jiaping Gu;
Hoeffer, Charles;
Sigurdsson, Einar M.

Publication type:

Article

A novel multiplex assay for simultaneous quantification of total and S129 phosphorylated human alpha-synuclein.

Published in:

Molecular Neurodegeneration, 2016, v. 11, p. 1, doi. 10.1186/s13024-016-0125-0

By:

Landeck, Natalie;
Hall, Hélène;
Ardah, Mustafa T.;
Majbour, Nour K.;
El-Agnaf, Omar M. A.;
Halliday, Glenda;
Kirik, Deniz

Publication type:

Article

The impact of glutamine supplementation on the symptoms of ataxia-telangiectasia: a preclinical assessment.

Published in:

Molecular Neurodegeneration, 2016, v. 11, p. 1, doi. 10.1186/s13024-016-0127-y

By:

Jianmin Chen;
Yanping Chen;
Vail, Graham;
Heiman Chow;
Yang Zhang;
Lauren Louie;
Jiali Li;
Hart, Ronald P.;
Plummer, Mark R.;
Herrup, Karl

Publication type:

Article

Deimmunization for gene therapy: host matching of synthetic zinc finger constructs enables long-term mutant Huntingtin repression in mice.

Published in:

Molecular Neurodegeneration, 2016, v. 11, p. 1, doi. 10.1186/s13024-016-0128-x

By:

Agustín-Pavón, Carmen;
Mielcarek, Michal;
Garriga-Canut, Mireia;
Isalan, Mark

Publication type:

Article

Lentiviral vector-mediated overexpression of mutant ataxin-7 recapitulates SCA7 pathology and promotes accumulation of the FUS/TLS and MBNL1 RNA-binding proteins.

Published in:

Molecular Neurodegeneration, 2016, v. 11, p. 1, doi. 10.1186/s13024-016-0123-2

By:

Alves, Sandro;
Marais, Thibaut;
Biferi, Maria-Grazia;
Furling, Denis;
Marinello, Martina;
Hachimi, Khalid El;
Cartier, Nathalie;
Ruberg, Merle;
Stevanin, Giovanni;
Brice, Alexis;
Barkats, Martine;
Sittler, Annie

Publication type:

Article

Erratum to: Transmission of α- synucleinopathy from olfactory structures deep into the temporal lobe.

Published in:

2016

By:

Mason, Daniel M.;
Nouraei, Negin;
Pant, Deepti B.;
Miner, Kristin M.;
Hutchison, Daniel F.;
Luk, Kelvin C.;
Stolz, John F.;
Leak, Rehana K.

Publication type:

Correction Notice

ZNStress: a high-throughput drug screening protocol for identification of compounds modulating neuronal stress in the transgenic mutant sod1G93R zebrafish model of amyotrophic lateral sclerosis.

Published in:

Molecular Neurodegeneration, 2016, v. 11, p. 1, doi. 10.1186/s13024-016-0122-3

By:

McGown, Alexander;
Shaw, Dame Pamela J.;
Ramesh, Tennore

Publication type:

Article

miR-27a and miR-27b regulate autophagic clearance of damaged mitochondria by targeting PTEN-induced putative kinase 1 (PINK1).

Published in:

Molecular Neurodegeneration, 2016, v. 11, p. 1, doi. 10.1186/s13024-016-0121-4

By:

Jaekwang Kim;
Fiesel, Fabienne C.;
Belmonte, Krystal C.;
Hudec, Roman;
Wang-Xia Wang;
Chaeyoung Kim;
Nelson, Peter T.;
Springer, Wolfdieter;
Jungsu Kim

Publication type:

Article

IKKβ-mediated inflammatory myeloid cell activation exacerbates experimental autoimmune encephalomyelitis by potentiating Th1/Th17 cell activation and compromising blood brain barrier.

Published in:

Molecular Neurodegeneration, 2016, v. 11, p. 1, doi. 10.1186/s13024-016-0116-1

By:

Min Jung Lee;
So Jin Bing;
Jonghee Choi;
Minhee Jang;
Gihyun Lee;
Hyunkyoung Lee;
Byung Soo Chang;
Youngheun Jee;
Sung Joong Lee;
Ik-Hyun Cho

Publication type:

Article

Pim1 inhibition as a novel therapeutic strategy for Alzheimer's disease.

Published in:

Molecular Neurodegeneration, 2016, v. 11, p. 1, doi. 10.1186/s13024-016-0118-z

By:

Velazquez, Ramon;
Shaw, Darren M.;
Caccamo, Antonella;
Oddo, Salvatore

Publication type:

Article

Early-life stress leads to impaired spatial learning and memory in middle-aged ApoE4-TR mice.

Published in:

Molecular Neurodegeneration, 2016, v. 11, p. 1, doi. 10.1186/s13024-016-0107-2

By:

Lan-yan Lin;
Jing Zhang;
Xiao-man Dai;
Nai-an Xiao;
Xi-lin Wu;
Zhen Wei;
Wen-ting Fang;
Yuan-gui Zhu;
Xiao-chun Chen

Publication type:

Article

Neurotrophic factor small-molecule mimetics mediated neuroregeneration and synaptic repair: emerging therapeutic modality for Alzheimer's disease.

Published in:

Molecular Neurodegeneration, 2016, v. 11, p. 1, doi. 10.1186/s13024-016-0119-y

By:

Kazim, Syed Faraz;
Iqbal, Khalid

Publication type:

Article

Immunotherapy targeting pyroglutamate-3 Aβ: prospects and challenges.

Published in:

Molecular Neurodegeneration, 2016, v. 11, p. 1, doi. 10.1186/s13024-016-0115-2

By:

Cynis, Holger;
Frost, Jeffrey L.;
Crehan, Helen;
Lemere, Cynthia A.

Publication type:

Article

Transmission of α-synucleinopathy from olfactory structures deep into the temporal lobe.

Published in:

Molecular Neurodegeneration, 2016, v. 11, p. 1, doi. 10.1186/s13024-016-0113-4

By:

Mason, Daniel M.;
Nouraei, Negin;
Pant, Deepti B.;
Miner, Kristin M.;
Hutchison, Daniel F.;
Luk, Kelvin C.;
Stolz, John F.;
Leak, Rehana K.

Publication type:

Article

Acetylated tau destabilizes the cytoskeleton in the axon initial segment and is mislocalized to the somatodendritic compartment.

Published in:

Molecular Neurodegeneration, 2016, v. 11, p. 1, doi. 10.1186/s13024-016-0109-0

By:

Dongmin Sohn, Peter;
Tracy, Tara E.;
Hye-In Son;
Yungui Zhou;
Leite, Renata E. P.;
Miller, Bruce L.;
Seeley, William W.;
Grinberg, Lea T.;
Li Gan

Publication type:

Article

Trehalose upregulates progranulin expression in human and mouse models of GRN haploinsufficiency: a novel therapeutic lead to treat frontotemporal dementia.

Published in:

Molecular Neurodegeneration, 2016, v. 11, p. 1, doi. 10.1186/s13024-016-0114-3

By:

Holler, Christopher J.;
Taylor, Georgia;
McEachin, Zachary T.;
Qiudong Deng;
Watkins, William J.;
Hudson, Kathryn;
Easley, Charles A.;
Hu, William T.;
Hales, Chadwick M.;
Rossoll, Wilfried;
Bassell, Gary J.;
Kukar, Thomas

Publication type:

Article

Redundant Gs-coupled serotonin receptors regulate amyloid-β metabolism in vivo.

Published in:

Molecular Neurodegeneration, 2016, v. 11, p. 1, doi. 10.1186/s13024-016-0112-5

By:

Fisher, Jonathan R.;
Wallace, Clare E.;
Tripoli, Danielle L.;
Sheline, Yvette I.;
Cirrito, John R.

Publication type:

Article

Synaptophysin depletion and intraneuronal Aβ in organotypic hippocampal slice cultures from huAPP transgenic mice.

Published in:

Molecular Neurodegeneration, 2016, v. 11, p. 1, doi. 10.1186/s13024-016-0110-7

By:

Harwell, Claire S.;
Coleman, Michael P.

Publication type:

Article

Stathmin 1/2-triggered microtubule loss mediates Golgi fragmentation in mutant SOD1 motor neurons.

Published in:

Molecular Neurodegeneration, 2016, v. 11, p. 1, doi. 10.1186/s13024-016-0111-6

By:

Bellouze, Sarah;
Baillat, Gilbert;
Buttigieg, Dorothée;
de la Grange, Pierre;
Rabouille, Catherine;
Haase, Georg

Publication type:

Article

Enrichment of extracellular vesicles from tissues of the central nervous system by PROSPR.

Published in:

Molecular Neurodegeneration, 2016, v. 11, p. 1, doi. 10.1186/s13024-016-0108-1

By:

Gallart-Palau, Xavier;
Serra, Aida;
Siu Kwan Sze

Publication type:

Article

Erratum to: Network-driven plasma proteomics expose molecular changes in the Alzheimer's brain.

Published in:: 2016
Publication type:: Correction Notice

Erratum to: A multifunctional therapeutic approach to disease modification in multiple familial mouse models and a novel sporadic model of Alzheimer's disease.

Published in:: 2016
Publication type:: Correction Notice

Induced pluripotent stem cells in Alzheimer's disease: applications for disease modeling and cell-replacement therapy.

Published in:

Molecular Neurodegeneration, 2016, v. 11, p. 1, doi. 10.1186/s13024-016-0106-3

By:

Juan Yang;
Song Li;
Xi-Biao He;
Cheng Cheng;
Weidong Le

Publication type:

Article

Accumulation of amyloid-β by astrocytes result in enlarged endosomes and microvesicle-induced apoptosis of neurons.

Published in:

Molecular Neurodegeneration, 2016, v. 11, p. 1, doi. 10.1186/s13024-016-0098-z

By:

Söllvander, Sofia;
Nikitidou, Elisabeth;
Brolin, Robin;
Söderberg, Linda;
Sehlin, Dag;
Lannfelt, Lars;
Erlandsson, Anna

Publication type:

Article

Apolipoprotein E lipoprotein particles inhibit amyloid-β uptake through cell surface heparan sulphate proteoglycan.

Published in:

Molecular Neurodegeneration, 2016, v. 11, p. 1, doi. 10.1186/s13024-016-0099-y

By:

Yuan Fu;
Jing Zhao;
Yuka Atagi;
Nielsen, Henrietta M.;
Chia-Chen Liu;
Honghua Zheng;
Mitsuru Shinohara;
Takahisa Kanekiyo;
Guojun Bu

Publication type:

Article

Targeting TDP-43 phosphorylation by Casein Kinase-1δ inhibitors: a novel strategy for the treatment of frontotemporal dementia.

Published in:

Molecular Neurodegeneration, 2016, v. 11, p. 1, doi. 10.1186/s13024-016-0102-7

By:

Alquezar, Carolina;
Salado, Irene G.;
de la Encarnación, Ana;
Pérez, Daniel I.;
Moreno, Fermín;
Gil, Carmen;
de Munain, Adolfo López;
Martínez, Ana;
Martín-Requero, Ángeles

Publication type:

Article

A multifunctional therapeutic approach to disease modification in multiple familial mouse models and a novel sporadic model of Alzheimer's disease.

Published in:

Molecular Neurodegeneration, 2016, v. 11, p. 1, doi. 10.1186/s13024-016-0103-6

By:

Jia Luo;
Lee, Sue H.;
VandeVrede, Lawren;
Zhihui Qin;
Aissa, Manel Ben;
Larson, John;
Teich, Andrew F.;
Arancio, Ottavio;
D'Souza, Yohan;
Elharram, Ahmed;
Koster, Kevin;
Tai, Leon M.;
LaDu, Mary Jo;
Bennett, Brian M.;
Thatcher, Gregory R. J.

Publication type:

Article

Vitamin D interacts with Esr1 and Igf1 to regulate molecular pathways relevant to Alzheimer's disease.

Published in:

Molecular Neurodegeneration, 2016, v. 11, p. 1, doi. 10.1186/s13024-016-0087-2

By:

Landel, Véréna;
Millet, Pascal;
Baranger, Kévin;
Loriod, Béatrice;
Féron, François

Publication type:

Article

Ex vivo imaging of active caspase 3 by a FRET-based molecular probe demonstrates the cellular dynamics and localization of the protease in cerebellar granule cells and its regulation by the apoptosis-inhibiting protein survivin.

Published in:

Molecular Neurodegeneration, 2016, v. 11, p. 1, doi. 10.1186/s13024-016-0101-8

By:

Lossi, Laura;
Cocito, Carolina;
Alasia, Silvia;
Merighi, Adalberto

Publication type:

Article

A seeding based cellular assay of tauopathy.

Published in:

Molecular Neurodegeneration, 2016, v. 11, p. 1, doi. 10.1186/s13024-016-0100-9

By:

Yin Xu;
Martini-Stoica, Heidi;
Hui Zheng

Publication type:

Article

Network-driven plasma proteomics expose molecular changes in the Alzheimer's brain.

Published in:

Molecular Neurodegeneration, 2016, v. 11, p. 1, doi. 10.1186/s13024-016-0095-2

By:

Jaeger, Philipp A.;
Lucin, Kurt M.;
Britschgi, Markus;
Vardarajan, Badri;
Ruo-Pan Huang;
Kirby, Elizabeth D.;
Abbey, Rachelle;
Boeve, Bradley F.;
Boxer, Adam L.;
Farrer, Lindsay A.;
Finch, NiCole;
Graff-Radford, Neill R.;
Head, Elizabeth;
Hoffree, Matan;
Ruochun Huang;
Johns, Hudson;
Karydas, Anna;
Knopman, David S.;
Loboda, Andrey;
Masliah, Eliezer

Publication type:

Article

In vitro and in vivo neuroprotective effects of cJun N-terminal kinase inhibitors on retinal ganglion cells.

Published in:

Molecular Neurodegeneration, 2016, v. 11, p. 1, doi. 10.1186/s13024-016-0093-4

By:

Byung-Jin Kim;
Silverman, Sean M.;
Yang Liu;
Wordinger, Robert J.;
Iok-Hou Pang;
Clark, Abbot F.

Publication type:

Article

The NLRP3 and NLRP1 inflammasomes are activated in Alzheimer's disease.

Published in:

Molecular Neurodegeneration, 2016, v. 11, p. 1, doi. 10.1186/s13024-016-0088-1

By:

Saresella, Marina;
La Rosa, Francesca;
Piancone, Federica;
Zoppis, Martina;
Marventano, Ivana;
Calabrese, Elena;
Rainone, Veronica;
Nemni, Raffaello;
Mancuso, Roberta;
Clerici, Mario

Publication type:

Article

Tau mutant A152T, a risk factor for FTD/PSP, induces neuronal dysfunction and reduced lifespan independently of aggregation in a C. elegans Tauopathy model.

Published in:

Molecular Neurodegeneration, 2016, v. 11, p. 1, doi. 10.1186/s13024-016-0096-1

By:

Pir, Ghulam Jeelani;
Choudhary, Bikash;
Mandelkow, Eckhard;
Mandelkow, Eva-Maria

Publication type:

Article

Resequencing analysis of five Mendelian genes and the top genes from genomewide association studies in Parkinson's Disease.

Published in:

Molecular Neurodegeneration, 2016, v. 11, p. 1, doi. 10.1186/s13024-016-0097-0

By:

Benitez, Bruno A.;
Davis, Albert A.;
Sheng Chih Jin;
Ibanez, Laura;
Ortega-Cubero, Sara;
Pastor, Pau;
Jiyoon Choi;
Cooper, Breanna;
Perlmutter, Joel S.;
Cruchaga, Carlos

Publication type:

Article

Inhibition of the classical pathway of the complement cascade prevents early dendritic and synaptic degeneration in glaucoma.

Published in:

Molecular Neurodegeneration, 2016, v. 11, p. 1, doi. 10.1186/s13024-016-0091-6

By:

Williams, Pete A.;
Tribble, James R.;
Pepper, Keating W.;
Cross, Stephen D.;
Morgan, B. Paul;
Morgan, James E.;
John, Simon W. M.;
Howell, Gareth R.

Publication type:

Article