Works matching IS 17501326 AND DT 2014 AND VI 9 AND IP 1

Results: 40

Andrographolide reduces cognitive impairment in young and mature AβPPswe/PS-1 mice.

Published in:

Molecular Neurodegeneration, 2014, v. 9, n. 1, p. 1, doi. 10.1186/1750-1326-9-61

By:

Serrano, Felipe G.;
Tapia-Rojas, Cheril;
Carvajal, Francisco J.;
Hancke, Juan;
Cerpa, Waldo;
Inestrosa, Nibaldo C.

Publication type:

Article

Increasing membrane cholesterol of neurons in culture recapitulates Alzheimer's disease early phenotypes.

Published in:

Molecular Neurodegeneration, 2014, v. 9, n. 1, p. 1, doi. 10.1186/1750-1326-9-60

By:

Marquer, Catherine;
Laine, Jeanne;
Dauphinot, Luce;
Hanbouch, Linda;
Lemercier-Neuillet, Camille;
Pierrot, Nathalie;
Bossers, Koen;
Le, Mickael;
Corlier, Fabian;
Benstaali, Caroline;
Saudou, Frédéric;
Thinakaran, Gopal;
Cartier, Nathalie;
Octave, Jean Noel;
Duyckaerts, Charles;
Potier, Marie-Claude

Publication type:

Article

Structural biology of presenilin 1 complexes.

Published in:

Molecular Neurodegeneration, 2014, v. 9, n. 1, p. 1, doi. 10.1186/1750-1326-9-59

By:

Yi Li;
Bohm, Christopher;
Dodd, Roger;
Fusheng Chen;
Qamar, Seema;
Schmitt-Ulms, Gerold;
Fraser, Paul E.;
St George-Hyslop, Peter H.

Publication type:

Article

Associations between brain microstructures, metabolites, and cognitive deficits during chronic HIV-1 infection of humanized mice.

Published in:

Molecular Neurodegeneration, 2014, v. 9, n. 1, p. 1, doi. 10.1186/1750-1326-9-58

By:

Boska, Michael D.;
Dash, Prasanta K.;
Knibbe, Jaclyn;
Epstein, Adrian A.;
Akhter, Sidra P.;
Fields, Natasha;
High, Robin;
Makarov, Edward;
Bonasera, Stephen;
Gelbard, Harris A.;
Poluektova, Larisa Y.;
Gendelman, Howard E.;
Gorantla, Santhi

Publication type:

Article

The cognitive defects of neonatally irradiated mice are accompanied by changed synaptic plasticity, adult neurogenesis and neuroinflammation.

Published in:

Molecular Neurodegeneration, 2014, v. 9, n. 1, p. 1, doi. 10.1186/1750-1326-9-57

By:

Kempf, Stefan J.;
Casciati, Arianna;
Buratovic, Sonja;
Janik, Dirk;
von Toerne, Christine;
Ueffing, Marius;
Neff, Frauke;
Moertl, Simone;
Stenerlöw, Bo;
Saran, Anna;
Atkinson, Michael J.;
Eriksson, Per;
Pazzaglia, Simonetta;
Tapio, Soile

Publication type:

Article

Interleukin-1β causes excitotoxic neurodegeneration and multiple sclerosis disease progression by activating the apoptotic protein p53.

Published in:

Molecular Neurodegeneration, 2014, v. 9, n. 1, p. 1, doi. 10.1186/1750-1326-9-56

By:

Rossi, Silvia;
Motta, Caterina;
Studer, Valeria;
Macchiarulo, Giulia;
Volpe, Elisabetta;
Barbieri, Francesca;
Ruocco, Gabriella;
Buttari, Fabio;
Finardi, Annamaria;
Mancino, Raffaele;
Weiss, Sagit;
Battistini, Luca;
Martino, Gianvito;
Furlan, Roberto;
Drulovic, Jelena;
Centonze, Diego

Publication type:

Article

Merging pathology with biomechanics using CHIMERA (Closed-Head Impact Model of Engineered Rotational Acceleration): a novel, surgery-free model of traumatic brain injury.

Published in:

Molecular Neurodegeneration, 2014, v. 9, n. 1, p. 218, doi. 10.1186/1750-1326-9-55

By:

Wai Hang Cheng;
Martens, Kris M.;
Carr, Michael;
Wilkinson, Anna;
Jianjia Fan;
Robert, Jerome;
Hayat, Arooj;
Namjoshi, Dhananjay R.;
Wellington, Cheryl L.;
McInnes, Kurt A.;
Cripton, Peter A.

Publication type:

Article

Long-term treadmill exercise attenuates tau pathology in P301S tau transgenic mice.

Published in:

Molecular Neurodegeneration, 2014, v. 9, n. 1, p. 187, doi. 10.1186/1750-1326-9-54

By:

Odochi Ohia-Nwoko;
Montazari, Saghi;
Eriksen, Jason L.;
Yuen-Sum Lau

Publication type:

Article

SNAP-25 is a promising novel cerebrospinal fluid biomarker for synapse degeneration in Alzheimer's disease.

Published in:

Molecular Neurodegeneration, 2014, v. 9, n. 1, p. 161, doi. 10.1186/1750-1326-9-53

By:

Brinkmalm, Ann;
Brinkmalm, Gunnar;
Wallin, Anders;
Blennow, Kaj;
Öhrfelt, Annika;
Zetterberg, Henrik;
Honer, William G.;
Frölich, Lutz;
Hausner, Lucrezia;
Minthon, Lennart;
Hansson, Oskar

Publication type:

Article

Tau pathogenesis is promoted by Aβ1-42 but not Aβ1-40.

Published in:

Molecular Neurodegeneration, 2014, v. 9, n. 1, p. 183, doi. 10.1186/1750-1326-9-52

By:

Xiaoyan Hu;
Gottesdiener, Andrew;
Wenjie Luo;
Paul, Steven;
Xiaoling Li;
Mingrui Zhao

Publication type:

Article

Models of beta-amyloid induced Tau-pathology: the long and "folded" road to understand the mechanism.

Published in:

Molecular Neurodegeneration, 2014, v. 9, n. 1, p. 155, doi. 10.1186/1750-1326-9-51

By:

Stancu, Ilie-Cosmin;
Vasconcelos, Bruno;
Dewachter, Ilse;
Terwel, Dick

Publication type:

Article

The impact of human and mouse differences in NOS2 gene expression on the brain's redox and immune environment.

Published in:

Molecular Neurodegeneration, 2014, v. 9, n. 1, p. 127, doi. 10.1186/1750-1326-9-50

By:

Hoos, Michael D.;
Vitek, Michael P.;
Wilson, Joan;
Jansen, Marilyn;
Everhart, Angela;
Colton, Carol A.;
Ridnour, Lisa A.;
Wink, David A.

Publication type:

Article

Increase of angiotensin II type 1 receptor auto-antibodies in Huntington's disease.

Published in:

Molecular Neurodegeneration, 2014, v. 9, n. 1, p. 108, doi. 10.1186/1750-1326-9-49

By:

Waschbisch, Anne;
De-Hyung Lee;
Linker, Ralf A.;
Schröder, Alexandra;
Hoffmann, Rainer;
Ellrichmann, Gisa;
Klotz, Peter;
Gold, Ralf;
Saft, Carsten;
Heidecke, Harald;
Paul, Friedemann;
Wachter, Rolf;
Dragun, Duska;
Stegbauer, Johannes;
Müller, Dominik N.;
Dechend, Ralf

Publication type:

Article

Oligomeric Aβ-induced synaptic dysfunction in Alzheimer's disease.

Published in:

Molecular Neurodegeneration, 2014, v. 9, n. 1, p. 80, doi. 10.1186/1750-1326-9-48

By:

Shichun Tu;
Shu-ichi Okamoto;
Stuart A. Lipton;
Huaxi Xu

Publication type:

Article

The role of the LRRK2 gene in Parkinsonism.

Published in:

Molecular Neurodegeneration, 2014, v. 9, n. 1, p. 46, doi. 10.1186/1750-1326-9-47

By:

Jie-Qiong Li;
Lan Tan;
Jin-Tai Yu

Publication type:

Article

Tau deletion impairs intracellular beta-amyloid-42 clearance and leads to more extracellular plaque deposition in gene transfer models.

Published in:

Molecular Neurodegeneration, 2014, v. 9, n. 1, p. 21, doi. 10.1186/1750-1326-9-46

By:

Lonskaya, Irina;
Hebron, Michaeline;
Moussa, Charbel;
Wenqiang Chen;
Schachter, Joel

Publication type:

Article

Pathogenic polyglutamine expansion length correlates with polarity of the flanking sequences.

Published in:

Molecular Neurodegeneration, 2014, v. 9, n. 1, p. 1, doi. 10.1186/1750-1326-9-45

By:

Meewhi Kim

Publication type:

Article

Gene expression changes consistent with neuroAIDS and impaired working memory in HIV-1 transgenic rats.

Published in:

Molecular Neurodegeneration, 2014, v. 9, n. 1, p. 1, doi. 10.1186/1750-1326-9-26

By:

Repunte-Canonigo, Vez;
Lefebvre, Celine;
George, Olivier;
Kawamura, Tomoya;
Morales, Marisela;
Koob, George;
Califano, Andrea;
Masliah, Eliezer;
Sanna, Pietro Paolo

Publication type:

Article

Epigenetic regulation of adult neural stem cells: implications for Alzheimer's disease.

Published in:

Molecular Neurodegeneration, 2014, v. 9, n. 1, p. 1, doi. 10.1186/1750-1326-9-25

By:

Fitzsimons, Carlos P.;
Bodegraven, Emma van;
Schouten, Marijn;
Lardenoije, Roy;
Kompotis, Konstantinos;
Kenis, Gunter;
den Hurk, Mark van;
Boks, Marco P.;
Biojone, Caroline;
Joca, Samia;
Steinbusch, Harry WM.;
Lunnon, Katie;
Mastroeni, Diego F.;
Mill, Jonathan;
Lucassen, Paul J.;
Coleman, Paul D.;
van den Hove, Daniel LA.;
Rutten, Bart PF.

Publication type:

Article

Prevention of intestinal obstruction reveals progressive neurodegeneration in mutant TDP-43 (A315T) mice.

Published in:

Molecular Neurodegeneration, 2014, v. 9, n. 1, p. 1, doi. 10.1186/1750-1326-9-24

By:

Herdewyn, Sarah;
Cirillo, Carla;
Van Den Bosch, Ludo;
Robberecht, Wim;
Berghe, Pieter Vanden;
Van Damme, Philip

Publication type:

Article

Vacuolar protein sorting 35 (Vps35) rescues locomotor deficits and shortened lifespan in Drosophila expressing a Parkinson's disease mutant of Leucine-rich repeat kinase 2 (LRRK2).

Published in:

Molecular Neurodegeneration, 2014, v. 9, n. 1, p. 1, doi. 10.1186/1750-1326-9-23

By:

Linhart, Radek;
Wong, Sarah Anne;
Cao, Jieyun;
Tran, Melody;
Huynh, Anne;
Ardrey, Casey;
Jong Min Park;
Christine Hsu;
Taha, Saher;
Peterson, Rentia;
Shea, Shannon;
Kurian, Jason;
Venderova, Katerina

Publication type:

Article

Identification of longitudinally dynamic biomarkers in Alzheimer's disease cerebrospinal fluid by targeted proteomics.

Published in:

Molecular Neurodegeneration, 2014, v. 9, n. 1, p. 1, doi. 10.1186/1750-1326-9-22

By:

Wildsmith, Kristin R.;
Schauer, Stephen P.;
Smith, Ashley M.;
Arnott, David;
Yuda Zhu;
Haznedar, Joshua;
Kaur, Surinder;
Rodney Mathews, W.;
Honigberg, Lee A.

Publication type:

Article

Ryanodine receptors: physiological function and deregulation in Alzheimer disease.

Published in:

Molecular Neurodegeneration, 2014, v. 9, n. 1, p. 2, doi. 10.1186/1750-1326-9-21

By:

Prete, Dolores Del;
Checler, Frédéric;
Chami, Mounia

Publication type:

Article

Altered microglial response to Aβ plaques in APPPS1-21 mice heterozygous for TREM2.

Published in:

Molecular Neurodegeneration, 2014, v. 9, n. 1, p. 3, doi. 10.1186/1750-1326-9-20

By:

Ulrich, Jason D.;
Finn, Mary Beth;
Wang, Yaming;
Shen, Alice;
Mahan, Thomas E.;
Jiang, Hong;
Stewart, Floy R.;
Piccio, Laura;
Colonna, Marco;
Holtzman, David M.

Publication type:

Article

Simplified method to perform CLARITY imaging.

Published in:

Molecular Neurodegeneration, 2014, v. 9, n. 1, p. 2, doi. 10.1186/1750-1326-9-19

By:

Poguzhelskaya, Ekaterina;
Artamonov, Dmitry;
Bolshakova, Anastasia;
Vlasova, Olga;
Bezprozvanny, Ilya

Publication type:

Article

Hippocampal neuronal cells that accumulate α- synuclein fragments are more vulnerable to Aβ oligomer toxicity via mGluR5 - implications for dementia with Lewy bodies.

Published in:

Molecular Neurodegeneration, 2014, v. 9, n. 1, p. 3, doi. 10.1186/1750-1326-9-18

By:

Overk, Cassia R.;
Cartier, Anna;
Shaked, Gideon;
Rockenstein, Edward;
Ubhi, Kiren;
Spencer, Brian;
Price, Diana L.;
Patrick, Christina;
Desplats, Paula;
Masliah, Eliezer

Publication type:

Article

The Parkinsonian mimetic, 6-OHDA, impairs axonal transport in dopaminergic axons.

Published in:

Molecular Neurodegeneration, 2014, v. 9, n. 1, p. 1, doi. 10.1186/1750-1326-9-17

By:

Xi Lu;
Jeong Sook Kim-Han;
Harmon, Steve;
Sakiyama-Elbert, Shelly E.;
O'Malley, Karen L.

Publication type:

Article

Increased mtDNA mutations with aging promotes amyloid accumulation and brain atrophy in the APP/Ld transgenic mouse model of Alzheimer's disease.

Published in:

Molecular Neurodegeneration, 2014, v. 9, n. 1, p. 1, doi. 10.1186/1750-1326-9-16

By:

Kukreja, Lokesh;
Kujoth, Gregory C.;
Prolla, Tomas A.;
Van Leuven, Fred;
Vassar, Robert

Publication type:

Article

U1 small nuclear ribonucleoproteins (snRNPs) aggregate in Alzheimer's disease due to autosomal dominant genetic mutations and trisomy 21.

Published in:

Molecular Neurodegeneration, 2014, v. 9, n. 1, p. 1, doi. 10.1186/1750-1326-9-15

By:

Hales, Chadwick M.;
Seyfried, Nicholas T.;
Dammer, Eric B.;
Duc Duong;
Hong Yi;
Gearing, Marla;
Troncoso, Juan C.;
Mufson, Elliott J.;
Thambisetty, Madhav;
Levey, Allan I.;
Lah, James J.

Publication type:

Article

Optic nerve crush induces spatial and temporal gene expression patterns in retina and optic nerve of BALB/cJ mice.

Published in:

Molecular Neurodegeneration, 2014, v. 9, n. 1, p. 1, doi. 10.1186/1750-1326-9-14

By:

Sharma, Tasneem P.;
McDowell, Colleen M.;
Yang Liu;
Wagner, Alex H.;
Thole, David;
Faga, Benjamin P.;
Wordinger, Robert J.;
Braun, Terry A.;
Clark, Abbot F.

Publication type:

Article

Abundance of Aβ<sub>5-x</sub> like immunoreactivity in transgenic 5XFAD, APP/PS1KI and 3xTG mice, sporadic and familial Alzheimer's disease.

Published in:

Molecular Neurodegeneration, 2014, v. 9, n. 1, p. 1, doi. 10.1186/1750-1326-9-13

By:

Avendaño Guzmán, Erika;
Bouter, Yvonne;
Richard, Bernhard C.;
Lannfelt, Lars;
Ingelsson, Martin;
Paetau, Anders;
Verkkoniemi-Ahola, Auli;
Wirths, Oliver;
Bayer, Thomas A.

Publication type:

Article

A consecutive case series experience with [<sup>18</sup> F] florbetapir PET imaging in an urban dementia center: impact on quality of life, decision making, and disposition.

Published in:

Molecular Neurodegeneration, 2014, v. 9, n. 1, p. 1, doi. 10.1186/1750-1326-9-10

By:

Mitsis, Effie M.;
Bender, Heidi A.;
Kostakoglu, Lale;
Machac, Josef;
Martin, Jane;
Woehr, Jennifer L.;
Sewell, Margaret C.;
Aloysi, Amy;
Goldstein, Martin A.;
Li, Clara;
Sano, Mary;
Gandy, Sam

Publication type:

Article

Effects of the C57BL/6 strain background on tauopathy progression in the rTg4510 mouse model.

Published in:

Molecular Neurodegeneration, 2014, v. 9, n. 1, p. 1, doi. 10.1186/1750-1326-9-8

By:

Bailey, Rachel M.;
Howard, John;
Knight, Joshua;
Sahara, Naruhiko;
Dickson, Dennis W.;
Lewis, Jada

Publication type:

Article

Binding of longer Aβ to transmembrane domain 1 of presenilin 1 impacts on Aβ42 generation.

Published in:

Molecular Neurodegeneration, 2014, v. 9, n. 1, p. 1, doi. 10.1186/1750-1326-9-7

By:

Yu Ohki;
Naoaki Shimada;
Aya Tominaga;
Satoko Osawa;
Takuya Higo;
Satoshi Yokoshima;
Tohru Fukuyama;
Taisuke Tomita;
Takeshi Iwatsubo

Publication type:

Article

Trafficking regulation of proteins in Alzheimer's disease.

Published in:

Molecular Neurodegeneration, 2014, v. 9, n. 1, p. 2, doi. 10.1186/1750-1326-9-6

By:

Shangtong Jiang;
Yanfang Li;
Xian Zhang;
Guojun Bu;
Huaxi Xu;
Yun-wu Zhang

Publication type:

Article

BACE1 activity regulates cell surface contactin-2 levels.

Published in:

Molecular Neurodegeneration, 2014, v. 9, n. 1, p. 1, doi. 10.1186/1750-1326-9-4

By:

Gautam, Vivek;
D'Avanzo, Carla;
Hebisch, Matthias;
Kovacs, Dora M.;
Doo Yeon Kim

Publication type:

Article

Stem cell derived basal forebrain cholinergic neurons from Alzheimer's disease patients are more susceptible to cell death.

Published in:

Molecular Neurodegeneration, 2014, v. 9, n. 1, p. 1, doi. 10.1186/1750-1326-9-3

By:

Duan, Lishu;
Bhattacharyya, Bula J.;
Belmadani, Abdelhak;
Pan, Liuliu;
Miller, Richard J.;
Kessler, John A.

Publication type:

Article

Soluble apoE/Abeta complex: mechanism and therapeutic target for APOE4-induced AD risk.

Published in:

2014

By:

Leon M. Tai;
Mehra, Shipra;
Shete, Varsha;
Estus, Steve;
William Rebeck, G.;
Guojun Bu;
Jo LaDu, Mary

Publication type:

Editorial

Axonal BACE1 dynamics and targeting in hippocampal neurons: a role for Rab11 GTPase.

Published in:

Molecular Neurodegeneration, 2014, v. 9, n. 1, p. 2, doi. 10.1186/1750-1326-9-1

By:

Buggia-Prévot, Virginie;
Fernandez, Celia G.;
Riordan, Sean;
Vetrivel, Kulandaivelu S.;
Roseman, Jelita;
Waters, Jack;
Bindokas, Vytautas P.;
Vassar, Robert;
Thinakaran, Gopal

Publication type:

Article

Amyloid peptides ABri and ADan show differential neurotoxicity in transgenic Drosophila models of familial British and Danish dementia.

Published in:

Molecular Neurodegeneration, 2014, v. 9, n. 1, p. 1, doi. 10.1186/1750-1326-9-5

By:

Marcora, María S.;
Fernández-Gamba, Agata C.;
Avendaño, Luz A.;
Rotondaro, Cecilia;
Podhajcer, Osvaldo L.;
Vidal, Rubén;
Morelli, Laura;
Ceriani, María F.;
Castaño, Eduardo M.

Publication type:

Article