Works matching IS 17501326 AND DT 2013 AND VI 8 AND IP 1

Results: 47

rAAV2/7 vector-mediated overexpression of alphasynuclein in mouse substantia nigra induces protein aggregation and progressive dose-dependent neurodegeneration.

Published in:

Molecular Neurodegeneration, 2013, v. 8, n. 1, p. 2, doi. 10.1186/1750-1326-8-44

By:

Oliveras-Salvá, Marusela;
Perren, Anke Van der;
Casadei, Nicolas;
Stroobants, Stijn;
Nuber, Silke;
D'Hooge, Rudi;
Haute, Chris Van den;
Baekelandt, Veerle

Publication type:

Article

Heat shock factor 1 over-expression protects against exposure of hydrophobic residues on mutant SOD1 and early mortality in a mouse model of amyotrophic lateral sclerosis.

Published in:

Molecular Neurodegeneration, 2013, v. 8, n. 1, p. 1, doi. 10.1186/1750-1326-8-43

By:

Lin, Pei-Yi;
Simon, Sharotka M.;
Koh, Won Kyun;
Folorunso, Oluwarotimi;
Umbaugh, Charles;
Pierce, Anson

Publication type:

Article

Histone deacetylase-3 interacts with ataxin-7 and is altered in a spinocerebellar ataxia type 7 mouse model.

Published in:

Molecular Neurodegeneration, 2013, v. 8, n. 1, p. 1, doi. 10.1186/1750-1326-8-42

By:

Duncan, Carlotta E.;
An, Mahru C.;
Papanikolaou, Theodora;
Rugani, Caitlin;
Vitelli, Cathy;
Ellerby, Lisa M.

Publication type:

Article

Modeling Alzheimer's disease in transgenic rats.

Published in:

Molecular Neurodegeneration, 2013, v. 8, n. 1, p. 1, doi. 10.1186/1750-1326-8-37

By:

Do Carmo, Sonia;
Cuello, A. Claudio

Publication type:

Article

Drosophila melanogaster as a model organism for Alzheimer's disease.

Published in:

Molecular Neurodegeneration, 2013, v. 8, n. 1, p. 1, doi. 10.1186/1750-1326-8-35

By:

Prüßing, Katja;
Voigt, Aaron;
Schulz, Jörg B.

Publication type:

Article

Endogenous expression of FAD-linked PS1 impairs proliferation, neuronal differentiation and survival of adult hippocampal progenitors.

Published in:

Molecular Neurodegeneration, 2013, v. 8, n. 1, p. 1, doi. 10.1186/1750-1326-8-41

By:

Veeraraghavalu, Karthikeyan;
Se Hoon Choi;
Xiaoqiong Zhang;
Sisodia, Sangram S.

Publication type:

Article

Sustained, neuron-specific IKK/NF-kappaB activation generates a selective neuroinflammatory response promoting local neurodegeneration with aging.

Published in:

Molecular Neurodegeneration, 2013, v. 8, n. 1, p. 1, doi. 10.1186/1750-1326-8-40

By:

Maqbool, Ayesha;
Lattke, Michael;
Wirth, Thomas;
Baumann, Bernd

Publication type:

Article

Blood--brain-barriers in aging and in Alzheimer's disease.

Published in:

Molecular Neurodegeneration, 2013, v. 8, n. 1, p. 1, doi. 10.1186/1750-1326-8-38

By:

Marques, Fernanda;
Sousa, João Carlos;
Sousa, Nuno;
Palha, Joana Almeida

Publication type:

Article

Immunotherapy for Alzheimer's disease: hoops and hurdles.

Published in:

Molecular Neurodegeneration, 2013, v. 8, n. 1, p. 1, doi. 10.1186/1750-1326-8-36

By:

Lemere, Cynthia A.

Publication type:

Article

Current concepts in Alzheimer's Disease: molecules, models and translational perspectives.

Published in:

Molecular Neurodegeneration, 2013, v. 8, n. 1, p. 1, doi. 10.1186/1750-1326-8-33

By:

Rutten, Bart P. F.;
Steinbusch, Harry W. M.

Publication type:

Article

Cross-talk of membrane lipids and Alzheimer-related proteins.

Published in:

Molecular Neurodegeneration, 2013, v. 8, n. 1, p. 1, doi. 10.1186/1750-1326-8-34

By:

Walter, Jochen;
van Echten-Deckert, Gerhild

Publication type:

Article

Heart fatty acid binding protein and Aβ-associated Alzheimer's neurodegeneration.

Published in:

Molecular Neurodegeneration, 2013, v. 8, n. 1, p. 1, doi. 10.1186/1750-1326-8-39

By:

Desikan, Rahul S.;
Thompson, Wesley K.;
Holland, Dominic;
Hess, Christopher P.;
Brewer, James B.;
Zetterberg, Henrik;
Blennow, Kaj;
Andreassen, Ole A.;
McEvoy, Linda K.;
Hyman, Bradley T.;
Dale, Anders M.

Publication type:

Article

Dominant optic atrophy, OPA1, and mitochondrial quality control: understanding mitochondrial network dynamics.

Published in:

Molecular Neurodegeneration, 2013, v. 8, n. 1, p. 1, doi. 10.1186/1750-1326-8-32

By:

Alavi, Marcel V.;
Fuhrmann, Nico

Publication type:

Article

Rapamycin increases survival in ALS mice lacking mature lymphocytes.

Published in:

Molecular Neurodegeneration, 2013, v. 8, n. 1, p. 1, doi. 10.1186/1750-1326-8-31

By:

Staats, Kim A.;
Hernandez, Sara;
Schönefeldt, Susann;
Bento-Abreu, André;
Dooley, James;
Van Damme, Philip;
Liston, Adrian;
Robberecht, Wim;
Van Den Bosch, Ludo

Publication type:

Article

Amyotrophic lateral sclerosis-linked FUS/TLS alters stress granule assembly and dynamics.

Published in:

Molecular Neurodegeneration, 2013, v. 8, n. 1, p. 1, doi. 10.1186/1750-1326-8-30

By:

Baron, Desiree M.;
Kaushansky, Laura J.;
Ward, Catherine L.;
Sama, Reddy Ranjith K.;
Chian, Ru-Ju;
Boggio, Kristin J.;
Quaresma, Alexandre J. C.;
Nickerson, Jeffrey A.;
Bosco, Daryl A.

Publication type:

Article

S-Nitrosylation of parkin as a novel regulator of p53-mediated neuronal cell death in sporadic Parkinson's disease.

Published in:

Molecular Neurodegeneration, 2013, v. 8, n. 1, p. 1, doi. 10.1186/1750-1326-8-29

By:

Sunico, Carmen R.;
Nakamura, Tomohiro;
Rockenstein, Edward;
Mante, Michael;
Adame, Anthony;
Chan, Shing Fai;
Newmeyer, Traci Fang;
Masliah, Eliezer;
Nakanishi, Nobuki;
Lipton, Stuart A.

Publication type:

Article

Genetics of amyotrophic lateral sclerosis: an update.

Published in:

Molecular Neurodegeneration, 2013, v. 8, n. 1, p. 1, doi. 10.1186/1750-1326-8-28

By:

Sheng Chen;
Sayana, Pavani;
Xiaojie Zhang;
Weidong Le

Publication type:

Article

Autophagy is involved in oligodendroglial precursor-mediated clearance of amyloid peptide.

Published in:

Molecular Neurodegeneration, 2013, v. 8, n. 1, p. 1, doi. 10.1186/1750-1326-8-27

By:

Wenxia Li;
Yifen Tang;
Zhiqin Fan;
Ya Meng;
Guang Yang;
Luo, Jia;
Zun-Ji Ke

Publication type:

Article

Correction: treatment with bexarotene, a compound that increases apolipoprotein-E, provides no cognitive benefit in mutant APP/PS1 mice.

Published in:

2013

By:

LaClair, Katherine D.;
Manaye, Kebreten F.;
Lee, Dexter L.;
Allard, Joanne S.;
Savonenko, Alena V.;
Troncoso, Juan C.;
Wong, Philip C.

Publication type:

Correction Notice

LRP1 is critical for the surface distribution and internalization of the NR2B NMDA receptor subtype.

Published in:

Molecular Neurodegeneration, 2013, v. 8, n. 1, p. 1, doi. 10.1186/1750-1326-8-25

By:

Maier, Wladislaw;
Bednorz, Mariola;
Meister, Sabrina;
Roebroek, Anton;
Weggen, Sascha;
Schmitt, Ulrich;
Pietrzik, Claus U.

Publication type:

Article

Overcoming barriers and thresholds - signaling of oligomeric Aβ through the prion protein to Fyn.

Published in:

Molecular Neurodegeneration, 2013, v. 8, n. 1, p. 1, doi. 10.1186/1750-1326-8-24

By:

Hansen Wang;
Ren, Carl He;
Geeth Gunawardana, C.;
Schmitt-Ulms, Gerold

Publication type:

Article

The synaptic maintenance problem: membrane recycling, Ca2+ homeostasis and late onset degeneration.

Published in:

Molecular Neurodegeneration, 2013, v. 8, n. 1, p. 1, doi. 10.1186/1750-1326-8-23

By:

Bezprozvanny, Ilya;
Hiesinger, Peter Robin

Publication type:

Article

Voluntary exercise protects against methamphetamine-induced oxidative stress in brain microvasculature and disruption of the blood-brain barrier.

Published in:

Molecular Neurodegeneration, 2013, v. 8, n. 1, p. 1, doi. 10.1186/1750-1326-8-22

By:

Toborek, Michal;
Seelbach, Melissa J.;
Rashid, Cetewayo S.;
András, Ibolya E.;
Chen, Lei;
Park, Minseon;
Esser, Karyn A.

Publication type:

Article

Fluid biomarkers in Alzheimer's disease - current concepts.

Published in:

Molecular Neurodegeneration, 2013, v. 8, n. 1, p. 1, doi. 10.1186/1750-1326-8-20

By:

Rosén, Christoffer;
Hansson, Oskar;
Blennow, Kaj;
Zetterberg, Henrik

Publication type:

Article

Progressive morphological changes and impaired retinal function associated with temporal regulation of gene expression after retinal ischemia/reperfusion injury in mice.

Published in:

Molecular Neurodegeneration, 2013, v. 8, n. 1, p. 1, doi. 10.1186/1750-1326-8-21

By:

Byung-Jin Kim;
Braun, Terry A.;
Wordinger, Robert J.;
Clark, Abbot F.

Publication type:

Article

TREM2 in neurodegeneration: evidence for association of the p.R47H variant with frontotemporal dementia and Parkinson's disease.

Published in:

Molecular Neurodegeneration, 2013, v. 8, n. 1, p. 1, doi. 10.1186/1750-1326-8-19

By:

Rayaprolu, Sruti;
Mullen, Bianca;
Baker, Matt;
Lynch, Timothy;
Finger, Elizabeth;
Seeley, William W.;
Hatanpaa, Kimmo J.;
Lomen-Hoerth, Catherine;
Kertesz, Andrew;
Bigio, Eileen H.;
Lippa, Carol;
Josephs, Keith A.;
Knopman, David S.;
White III, Charles L.;
Caselli, Richard;
Mackenzie, Ian R.;
Miller, Bruce L.;
Boczarska-Jedynak, Magdalena;
Opala, Grzegorz;
Krygowska-Wajs, Anna

Publication type:

Article

Treatment with bexarotene, a compound that increases apolipoprotein-E, provides no cognitive benefit in mutant APP/PS1 mice.

Published in:

Molecular Neurodegeneration, 2013, v. 8, n. 1, p. 1, doi. 10.1186/1750-1326-8-18

By:

LaClair, Katherine D.;
Manaye, Kebreten F.;
Lee, Dexter L.;
Allard, Joanne S.;
Savonenko, Alena V.;
Troncoso, Juan C.;
Wong, Philip C.

Publication type:

Article

Conformational templating of α-synuclein aggregates in neuronal-glial cultures.

Published in:

Molecular Neurodegeneration, 2013, v. 8, n. 1, p. 1, doi. 10.1186/1750-1326-8-17

By:

Sacino, Amanda N.;
Thomas, Michael A.;
Ceballos-Diaz, Carolina;
Cruz, Pedro E.;
Rosario, Awilda M.;
Lewis, Jada;
Giasson, Benoit I.;
Golde, Todd E.

Publication type:

Article

ApoE4 induces Aβ42, tau, and neuronal pathology in the hippocampus of young targeted replacement apoE4 mice.

Published in:

Molecular Neurodegeneration, 2013, v. 8, n. 1, p. 1, doi. 10.1186/1750-1326-8-16

By:

Liraz, Ori;
Boehm-Cagan, Anat;
Michaelson, Daniel M.

Publication type:

Article

Normal cognition in transgenic BRI2-Aβ mice.

Published in:

Molecular Neurodegeneration, 2013, v. 8, n. 1, p. 1, doi. 10.1186/1750-1326-8-15

By:

Kim, Jungsu;
Chakrabarty, Paramita;
Hanna, Amanda;
March, Amelia;
Dickson, Dennis W.;
Borchelt, David R.;
Golde, Todd;
Janus, Christopher

Publication type:

Article

Behavioral characterization of the 6-hydroxidopamine model of Parkinson's disease and pharmacological rescuing of non-motor deficits.

Published in:

Molecular Neurodegeneration, 2013, v. 8, n. 1, p. 1, doi. 10.1186/1750-1326-8-14

By:

Carvalho, Miguel M.;
Campos, Filipa L.;
Coimbra, Bárbara;
Pêgo, José M.;
Rodrigues, Carla;
Lima, Rui;
Rodrigues, Ana J.;
Sousa, Nuno;
Salgado, António J.

Publication type:

Article

In vivo measurement of apolipoprotein E from the brain interstitial fluid using microdialysis.

Published in:

Molecular Neurodegeneration, 2013, v. 8, n. 1, p. 1, doi. 10.1186/1750-1326-8-13

By:

Ulrich, Jason D.;
Burchett, Jack M.;
Restivo, Jessica L.;
Schuler, Dorothy R;
Verghese, Philip B.;
Mahan, Thomas E.;
Landreth, Gary E.;
Castellano, Joseph M.;
Jiang, Hong;
Cirrito, John R.;
Holtzman, David M.

Publication type:

Article

Aggregation and neurotoxicity of recombinant α-synuclein aggregates initiated by dimerization.

Published in:

Molecular Neurodegeneration, 2013, v. 8, n. 1, p. 1, doi. 10.1186/1750-1326-8-5

By:

Roostaee, Alireza;
Beaudoin, Simon;
Staskevicius, Antanas;
Roucou, Xavier

Publication type:

Article

Simultaneous and independent detection of C9ORF72 alleles with low and high number of GGGGCC repeats using an optimised protocol of Southern blot hybridisation.

Published in:

Molecular Neurodegeneration, 2013, v. 8, n. 1, p. 1, doi. 10.1186/1750-1326-8-12

By:

Buchman, Vladimir L.;
Cooper-Knock, Johnathan;
Connor-Robson, Natalie;
Higginbottom, Adrian;
Kirby, Janine;
Razinskaya, Olga D.;
Ninkina, Natalia;
Shaw, Pamela J.

Publication type:

Article

Reviewer acknowledgement.

Published in:

Molecular Neurodegeneration, 2013, v. 8, n. 1, p. 1, doi. 10.1186/1750-1326-8-11

By:

Guojun Bu;
Huaxi Xu

Publication type:

Article

Role of p73 in Alzheimer disease: lack of association in mouse models or in human cohorts.

Published in:

Molecular Neurodegeneration, 2013, v. 8, n. 1, p. 1, doi. 10.1186/1750-1326-8-10

By:

Vardarajan, Badri;
Vergote, David;
Tissir, Fadel;
Logue, Mark;
Jing Yang;
Daude, Nathalie;
Ando, Kunie;
Rogaeva, Ekaterina;
Lee, Joseph;
Cheng, Rong;
Brion, Jean-Pierre;
Ghani, Mahdi;
Shi, Beipei;
Baldwin, Clinton T.;
Kar, Satyabrata;
Mayeux, Richard;
Fraser, Paul;
Goffinet, André M.;
George-Hyslop, Peter St;
Farrer, Lindsay A.

Publication type:

Article

Age-dependent roles of peroxisomes in the hippocampus of a transgenic mouse model of Alzheimer's disease.

Published in:

Molecular Neurodegeneration, 2013, v. 8, n. 1, p. 19, doi. 10.1186/1750-1326-8-8

By:

Fanelli, Francesca;
Sepe, Sara;
D'Amelio, Marcello;
Bernardi, Cinzia;
Cristiano, Loredana;
Cimini, Anna Maria;
Cecconi, Francesco;
Ceru, Maria Paola;
Moreno, Sandra

Publication type:

Article

HDAC6 as a target for neurodegenerative diseases: what makes it different from the other HDACs?

Published in:

Molecular Neurodegeneration, 2013, v. 8, n. 1, p. 1, doi. 10.1186/1750-1326-8-7

By:

Simões-Pires, Claudia;
Zwick, Vincent;
Nurisso, Alessandra;
Schenker, Esther;
Carrupt, Pierre-Alain;
Cuendet, Muriel

Publication type:

Article

Kinetics of neurodegeneration based on a risk-related biomarker in animal model of glaucoma.

Published in:

Molecular Neurodegeneration, 2013, v. 8, n. 1, p. 1, doi. 10.1186/1750-1326-8-4

By:

Hayashi, Takuya;
Shimazawa, Masamitsu;
Watabe, Hiroshi;
Ose, Takayuki;
Inokuchi, Yuta;
Ito, Yasushi;
Yamanaka, Hajime;
Urayama, Shin-ichi;
Watanabe, Yasuyoshi;
Hara, Hideaki;
Onoe, Hirotaka

Publication type:

Article

Aß impairs nicotinic regulation of inhibitory synaptic transmission and interneuron excitability in prefrontal cortex.

Published in:

Molecular Neurodegeneration, 2013, v. 8, n. 1, p. 1, doi. 10.1186/1750-1326-8-3

By:

Chen, Guo-Jun;
Zhe Xiong;
Zhen Yan

Publication type:

Article

In vivo functional brain mapping in a conditional mouse model of human tauopathy (taup301l) reveals reduced neural activity in memory formation structures.

Published in:

Molecular Neurodegeneration, 2013, v. 8, n. 1, p. 1, doi. 10.1186/1750-1326-8-9

By:

Perez, Pablo D.;
Hall, Gabrielle;
Kimura, Tetsuya;
Ren, Yan;
Bailey, Rachel M.;
Lewis, Jada;
Febo, Marcelo;
Sahara, Naruhiko

Publication type:

Article

Behavioral and transcriptome alterations in male and female mice with postnatal deletion of TrkB in dorsal striatal medium spiny neurons.

Published in:

Molecular Neurodegeneration, 2013, v. 8, n. 1, p. 2, doi. 10.1186/1750-1326-8-47

By:

Unterwald, Ellen M.;
Page, Michelle E.;
Brown, Timothy B.;
Miller, Jonathan S.;
Ruiz, Marta;
Pescatore, Karen A.;
Baoji Xu;
Reichardt, Louis French;
Beverley, Joel;
Bin Tang;
Steiner, Heinz;
Thomas, Elizabeth A.;
Ehrlich, Michelle E.

Publication type:

Article

Features of wild-type human SOD1 limit interactions with misfolded aggregates of mouse G86R Sod1.

Published in:

Molecular Neurodegeneration, 2013, v. 8, n. 1, p. 2, doi. 10.1186/1750-1326-8-46

By:

Qualls, David A.;
Prudencio, Mercedes;
Roberts, Brittany L.T.;
Crosby, Keith;
Brown, Hilda;
Borchelt, David R.

Publication type:

Article

Mitochondrial permeability transition pore induces mitochondria injury in Huntington disease.

Published in:

Molecular Neurodegeneration, 2013, v. 8, n. 1, p. 2, doi. 10.1186/1750-1326-8-45

By:

Quintanilla, Rodrigo A.;
Youngnam N. Jin;
Von Bernhardi, Rommy;
Johnson, Gail V.W.

Publication type:

Article

Neuron loss in the 5XFAD mouse model of Alzheimer's disease correlates with intraneuronal Aβ42 accumulation and Caspase-3 activation.

Published in:

Molecular Neurodegeneration, 2013, v. 8, n. 1, p. 1, doi. 10.1186/1750-1326-8-2

By:

Eimer, William A.;
Vassar, Robert

Publication type:

Article

Mitochondrial quality, dynamics and functional capacity in Parkinson's disease cybrid cell lines selected for Lewy body expression.

Published in:

Molecular Neurodegeneration, 2013, v. 8, n. 1, p. 1, doi. 10.1186/1750-1326-8-6

By:

Cronin-Furman, Emily N.;
Kathleen Borland, M.;
Bergquist, Kristen E.;
Bennett Jr., James P.;
Trimmer, Patricia A.

Publication type:

Article

Widespread aggregation of mutant VAPB associated with ALS does not cause motor neuron degeneration or modulate mutant SOD1 aggregation and toxicity in mice.

Published in:

Molecular Neurodegeneration, 2013, v. 8, n. 1, p. 1, doi. 10.1186/1750-1326-8-1

By:

Linghua Qiu;
Tao Qiao;
Melissa Beers;
Weijia Tan;
Hongyan Wang;
Bin Yang;
Zuoshang Xu

Publication type:

Article