Works matching IS 17501326 AND DT 2012 AND VI 7


Results: 136
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    Defective lysosomal proteolysis and axonal transport are early pathogenic events that worsen with age leading to increased APP metabolism and synaptic Abeta in transgenic APP/PS1 hippocampus.

    Published in:
    Molecular Neurodegeneration, 2012, v. 7, n. 1, p. 1, doi. 10.1186/1750-1326-7-59
    By:
    • Torres, Manuel;
    • Jimenez, Sebastian;
    • Sanchez-Varo, Raquel;
    • Navarro, Victoria;
    • Trujillo-Estrada, Laura;
    • Sanchez-Mejias, Elisabeth;
    • Carmona, Irene;
    • Carlos Davila, Jose;
    • Vizuete, Marisa;
    • Gutierrez, Antonia;
    • Vitorica, Javier
    Publication type:
    Article
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    Modulation of γ-secretase by EVP-0015962 reduces amyloid deposition and behavioral deficits in Tg2576 mice.

    Published in:
    Molecular Neurodegeneration, 2012, v. 7, n. 1, p. 1, doi. 10.1186/1750-1326-7-61
    By:
    • Rogers, Kathryn;
    • Felsenstein, Kevin M;
    • Hrdlicka, Lori;
    • Tu, Zhiming;
    • Albayya, Faris;
    • Lee, Winnie;
    • Hopp, Sarah;
    • Miller, Mary-Jo;
    • Spaulding, Darcie;
    • Yang, Zhiyong;
    • Hodgdon, Hilliary;
    • Nolan, Scott;
    • Wen, Melody;
    • Costa, Don;
    • Blain, Jean-Francois;
    • Freeman, Emily;
    • De Strooper, Bart;
    • Vulsteke, Veerle;
    • Scrocchi, Louise;
    • Zetterberg, Henrik
    Publication type:
    Article
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