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APOE2: protective mechanism and therapeutic implications for Alzheimer's disease.
- Published in:
- Molecular Neurodegeneration, 2020, v. 15, n. 1, p. N.PAG, doi. 10.1186/s13024-020-00413-4
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- Publication type:
- Article
Modeling the β-secretase cleavage site and humanizing amyloid-beta precursor protein in rat and mouse to study Alzheimer's disease.
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- Molecular Neurodegeneration, 2020, v. 15, n. 1, p. 1, doi. 10.1186/s13024-020-00399-z
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- Publication type:
- Article
Conformation-selective tau monoclonal antibodies inhibit tau pathology in primary neurons and a mouse model of Alzheimer's disease.
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- Molecular Neurodegeneration, 2020, v. 15, n. 1, p. N.PAG, doi. 10.1186/s13024-020-00404-5
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- Publication type:
- Article
The Alzheimer's disease-associated protective Plcγ2-P522R variant promotes immune functions.
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- Molecular Neurodegeneration, 2020, v. 15, n. 1, p. N.PAG, doi. 10.1186/s13024-020-00402-7
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- Publication type:
- Article
Aging-relevant human basal forebrain cholinergic neurons as a cell model for Alzheimer's disease.
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- Molecular Neurodegeneration, 2020, v. 15, n. 1, p. N.PAG, doi. 10.1186/s13024-020-00411-6
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- Publication type:
- Article
Cell-autonomous role of Presenilin in age-dependent survival of cortical interneurons.
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- Molecular Neurodegeneration, 2020, v. 15, n. 1, p. 1, doi. 10.1186/s13024-020-00419-y
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- Publication type:
- Article
Astrocyte-derived clusterin suppresses amyloid formation in vivo.
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- Molecular Neurodegeneration, 2020, v. 15, n. 1, p. N.PAG, doi. 10.1186/s13024-020-00416-1
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- Publication type:
- Article
Regional binding of tau and amyloid PET tracers in Down syndrome autopsy brain tissue.
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- Molecular Neurodegeneration, 2020, v. 15, n. 1, p. 1, doi. 10.1186/s13024-020-00414-3
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- Publication type:
- Article
An in vitro bioengineered model of the human arterial neurovascular unit to study neurodegenerative diseases.
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- Molecular Neurodegeneration, 2020, v. 15, n. 1, p. N.PAG, doi. 10.1186/s13024-020-00418-z
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- Publication type:
- Article
Activity of Alzheimer's γ-secretase is linked to changes of interferon-induced transmembrane proteins (IFITM) in innate immunity.
- Published in:
- 2020
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- Publication type:
- Letter
A novel systems biology approach to evaluate mouse models of late-onset Alzheimer’s disease.
- Published in:
- Molecular Neurodegeneration, 2020, v. 15, n. 1, p. 1, doi. 10.1186/s13024-020-00412-5
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- Publication type:
- Article
Diabetic phenotype in mouse and humans reduces the number of microglia around β-amyloid plaques.
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- Molecular Neurodegeneration, 2020, v. 15, n. 1, p. N.PAG, doi. 10.1186/s13024-020-00415-2
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- Publication type:
- Article
Tauopathy-associated tau modifications selectively impact neurodegeneration and mitophagy in a novel C. elegans single-copy transgenic model.
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- Molecular Neurodegeneration, 2020, v. 15, n. 1, p. N.PAG, doi. 10.1186/s13024-020-00410-7
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- Publication type:
- Article
Glycosphingolipids and neuroinflammation in Parkinson's disease.
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- Molecular Neurodegeneration, 2020, v. 15, n. 1, p. N.PAG, doi. 10.1186/s13024-020-00408-1
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- Publication type:
- Article
Neurofilaments in motor neuron disorders: towards promising diagnostic and prognostic biomarkers.
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- Molecular Neurodegeneration, 2020, v. 15, n. 1, p. N.PAG, doi. 10.1186/s13024-020-00406-3
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- Publication type:
- Article
Trem2 Y38C mutation and loss of Trem2 impairs neuronal synapses in adult mice.
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- Molecular Neurodegeneration, 2020, v. 15, n. 1, p. N.PAG, doi. 10.1186/s13024-020-00409-0
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- Publication type:
- Article
Peroxiredoxin 6 mediates protective function of astrocytes in Aβ proteostasis.
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- Molecular Neurodegeneration, 2020, v. 15, n. 1, p. 1, doi. 10.1186/s13024-020-00401-8
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- Publication type:
- Article
Higher CSF sTREM2 attenuates ApoE4-related risk for cognitive decline and neurodegeneration.
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- Molecular Neurodegeneration, 2020, v. 15, n. 1, p. N.PAG, doi. 10.1186/s13024-020-00407-2
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- Publication type:
- Article
Correction to: Deciphering cellular transcriptional alterations in Alzheimer's disease brains.
- Published in:
- 2020
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- Publication type:
- Correction Notice
Behavioral and neural network abnormalities in human APP transgenic mice resemble those of App knock-in mice and are modulated by familial Alzheimer's disease mutations but not by inhibition of BACE1.
- Published in:
- Molecular Neurodegeneration, 2020, v. 15, n. 1, p. N.PAG, doi. 10.1186/s13024-020-00393-5
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- Publication type:
- Article
BIN1 protein isoforms are differentially expressed in astrocytes, neurons, and microglia: neuronal and astrocyte BIN1 are implicated in tau pathology.
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- Molecular Neurodegeneration, 2020, v. 15, n. 1, p. 1, doi. 10.1186/s13024-020-00387-3
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- Publication type:
- Article
Integrated analysis of the aging brain transcriptome and proteome in tauopathy.
- Published in:
- Molecular Neurodegeneration, 2020, v. 15, n. 1, p. N.PAG, doi. 10.1186/s13024-020-00405-4
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- Publication type:
- Article
Neuroimaging advances regarding subjective cognitive decline in preclinical Alzheimer's disease.
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- Molecular Neurodegeneration, 2020, v. 15, n. 1, p. N.PAG, doi. 10.1186/s13024-020-00395-3
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- Publication type:
- Article
Impaired NHEJ repair in amyotrophic lateral sclerosis is associated with TDP-43 mutations.
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- Molecular Neurodegeneration, 2020, v. 15, n. 1, p. 1, doi. 10.1186/s13024-020-00386-4
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- Publication type:
- Article
CNS axonal degeneration and transport deficits at the optic nerve head precede structural and functional loss of retinal ganglion cells in a mouse model of glaucoma.
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- Molecular Neurodegeneration, 2020, v. 15, n. 1, p. N.PAG, doi. 10.1186/s13024-020-00400-9
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- Publication type:
- Article
Microbial involvement in Alzheimer disease development and progression.
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- Molecular Neurodegeneration, 2020, v. 15, n. 1, p. 1, doi. 10.1186/s13024-020-00378-4
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- Publication type:
- Article
Cerebrospinal fluid profile of NPTX2 supports role of Alzheimer's disease-related inhibitory circuit dysfunction in adults with Down syndrome.
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- Molecular Neurodegeneration, 2020, v. 15, n. 1, p. N.PAG, doi. 10.1186/s13024-020-00398-0
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- Publication type:
- Article
The role of TDP-43 mislocalization in amyotrophic lateral sclerosis.
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- Molecular Neurodegeneration, 2020, v. 15, n. 1, p. N.PAG, doi. 10.1186/s13024-020-00397-1
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- Publication type:
- Article
Two C-terminal sequence variations determine differential neurotoxicity between human and mouse α-synuclein.
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- Molecular Neurodegeneration, 2020, v. 15, n. 1, p. N.PAG, doi. 10.1186/s13024-020-00380-w
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- Publication type:
- Article
Integrated analysis of ultra-deep proteomes in cortex, cerebrospinal fluid and serum reveals a mitochondrial signature in Alzheimer's disease.
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- Molecular Neurodegeneration, 2020, v. 15, n. 1, p. 1, doi. 10.1186/s13024-020-00384-6
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- Publication type:
- Article
P2RX7 inhibitor suppresses exosome secretion and disease phenotype in P301S tau transgenic mice.
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- Molecular Neurodegeneration, 2020, v. 15, n. 1, p. N.PAG, doi. 10.1186/s13024-020-00396-2
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- Publication type:
- Article
Trem2 deficiency differentially affects phenotype and transcriptome of human APOE3 and APOE4 mice.
- Published in:
- Molecular Neurodegeneration, 2020, v. 15, n. 1, p. 1, doi. 10.1186/s13024-020-00394-4
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- Publication type:
- Article
Molecular and cellular mechanisms underlying the pathogenesis of Alzheimer's disease.
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- Molecular Neurodegeneration, 2020, v. 15, n. 1, p. 1, doi. 10.1186/s13024-020-00391-7
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- Publication type:
- Article
FRET-based Tau seeding assay does not represent prion-like templated assembly of Tau filaments.
- Published in:
- Molecular Neurodegeneration, 2020, v. 15, n. 1, p. 1, doi. 10.1186/s13024-020-00389-1
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- Publication type:
- Article
Deciphering cellular transcriptional alterations in Alzheimer's disease brains.
- Published in:
- Molecular Neurodegeneration, 2020, v. 15, n. 1, p. 1, doi. 10.1186/s13024-020-00392-6
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- Publication type:
- Article
From basic research to the clinic: innovative therapies for ALS and FTD in the pipeline.
- Published in:
- Molecular Neurodegeneration, 2020, v. 15, n. 1, p. 1, doi. 10.1186/s13024-020-00373-9
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- Publication type:
- Article
Correction to: Divergence, Convergence, and Therapeutic Implications: A Cell Biology Perspective of C9ORF72-ALS/FTD.
- Published in:
- 2020
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- Publication type:
- Correction Notice
Sex-dependent calcium hyperactivity due to lysosomal-related dysfunction in astrocytes from APOE4 versus APOE3 gene targeted replacement mice.
- Published in:
- Molecular Neurodegeneration, 2020, v. 15, n. 1, p. 1, doi. 10.1186/s13024-020-00382-8
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- Publication type:
- Article
Divergence, Convergence, and Therapeutic Implications: A Cell Biology Perspective of C9ORF72-ALS/FTD.
- Published in:
- Molecular Neurodegeneration, 2020, v. 15, n. 1, p. 1, doi. 10.1186/s13024-020-00383-7
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- Publication type:
- Article
Utility of plasma Neurofilament light as a diagnostic and prognostic biomarker of the postural instability gait disorder motor subtype in early Parkinson's disease.
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- Molecular Neurodegeneration, 2020, v. 15, n. 1, p. 1, doi. 10.1186/s13024-020-00385-5
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- Publication type:
- Article
Harnessing regulatory T cell neuroprotective activities for treatment of neurodegenerative disorders.
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- Molecular Neurodegeneration, 2020, v. 15, n. 1, p. 1, doi. 10.1186/s13024-020-00375-7
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- Publication type:
- Article
Identification of novel cerebrospinal fluid biomarker candidates for dementia with Lewy bodies: a proteomic approach.
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- Molecular Neurodegeneration, 2020, v. 15, n. 1, p. 1, doi. 10.1186/s13024-020-00388-2
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- Publication type:
- Article
Circulating cell-free mitochondrial DNA levels in Parkinson's disease are influenced by treatment.
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- Molecular Neurodegeneration, 2020, v. 15, n. 1, p. 1, doi. 10.1186/s13024-020-00362-y
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- Publication type:
- Article
Therapeutic approaches targeting Apolipoprotein E function in Alzheimer's disease.
- Published in:
- Molecular Neurodegeneration, 2020, v. 15, n. 1, p. 1, doi. 10.1186/s13024-020-0358-9
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- Publication type:
- Article
Elevated methylation levels, reduced expression levels, and frequent contractions in a clinical cohort of C9orf72 expansion carriers.
- Published in:
- Molecular Neurodegeneration, 2020, v. 15, n. 1, p. 1, doi. 10.1186/s13024-020-0359-8
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- Publication type:
- Article
A pharmacological chaperone improves memory by reducing Aβ and tau neuropathology in a mouse model with plaques and tangles.
- Published in:
- Molecular Neurodegeneration, 2020, v. 15, n. 1, p. 1, doi. 10.1186/s13024-019-0350-4
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- Publication type:
- Article
Correction to: Reduced sphingolipid hydrolase activities, substrate accumulation and ganglioside decline in Parkinson's disease.
- Published in:
- 2020
- By:
- Publication type:
- Correction Notice
Mitochondria dysfunction in the pathogenesis of Alzheimer's disease: recent advances.
- Published in:
- Molecular Neurodegeneration, 2020, v. 15, n. 1, p. 1, doi. 10.1186/s13024-020-00376-6
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- Publication type:
- Article
Interleukin-6 deficiency exacerbates Huntington's disease model phenotypes.
- Published in:
- Molecular Neurodegeneration, 2020, v. 15, n. 1, p. 1, doi. 10.1186/s13024-020-00379-3
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- Publication type:
- Article
Flow-cytometric microglial sorting coupled with quantitative proteomics identifies moesin as a highly-abundant microglial protein with relevance to Alzheimer's disease.
- Published in:
- Molecular Neurodegeneration, 2020, v. 15, n. 1, p. 1, doi. 10.1186/s13024-020-00377-5
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- Publication type:
- Article