Works in Molecular Neurodegeneration, 2017, Vol 12

Results: 90

Correction to: Gene-environment interaction between lead and Apolipoprotein E4 causes cognitive behavior deficits in mice.

Published in:: 2017
Publication type:: Correction Notice

Iron regulatory protein (IRP)-iron responsive element (IRE) signaling pathway in human neurodegenerative diseases.

Published in:

Molecular Neurodegeneration, 2017, v. 12, p. 1, doi. 10.1186/s13024-017-0218-4

By:

Zhi Dong Zhou;
Eng-King Tan

Publication type:

Article

Multiscale network modeling of oligodendrocytes reveals molecular components of myelin dysregulation in Alzheimer's disease.

Published in:

Molecular Neurodegeneration, 2017, v. 12, p. 1, doi. 10.1186/s13024-017-0219-3

By:

McKenzie, Andrew T.;
Moyon, Sarah;
Minghui Wang;
Katsyv, Igor;
Won-Min Song;
Xianxiao Zhou;
Dammer, Eric B.;
Duong, Duc M.;
Aaker, Joshua;
Yongzhong Zhao;
Beckmann, Noam;
Pei Wang;
Jun Zhu;
Lah, James J.;
Seyfried, Nicholas T.;
Levey, Allan I.;
Katsel, Pavel;
Haroutunian, Vahram;
Schadt, Eric E.;
Popko, Brian

Publication type:

Article

YKL-40 in the brain and cerebrospinal fluid of neurodegenerative dementias.

Published in:

Molecular Neurodegeneration, 2017, v. 12, p. 1, doi. 10.1186/s13024-017-0226-4

By:

Llorens, Franc;
Thüne, Katrin;
Tahir, Waqas;
Kanata, Eirini;
Diaz-Lucena, Daniela;
Xanthopoulos, Konstantinos;
Kovatsi, Eleni;
Pleschka, Catharina;
Garcia-Esparcia, Paula;
Schmitz, Matthias;
Ozbay, Duru;
Correia, Susana;
Correia, Ângela;
Milosevic, Ira;
Andréoletti, Olivier;
Fernández-Borges, Natalia;
Vorberg, Ina M.;
Glatzel, Markus;
Sklaviadis, Theodoros;
Torres, Juan Maria

Publication type:

Article

Is amyotrophic lateral sclerosis/frontotemporal dementia an autophagy disease?

Published in:

Molecular Neurodegeneration, 2017, v. 12, p. 1, doi. 10.1186/s13024-017-0232-6

By:

Zhiqiang Deng;
Sheehan, Patricia;
Shi Chen;
Zhenyu Yue

Publication type:

Article

Practical considerations for choosing a mouse model of Alzheimer's disease.

Published in:

Molecular Neurodegeneration, 2017, v. 12, p. 1, doi. 10.1186/s13024-017-0231-7

By:

Jankowsky, Joanna L.;
Hui Zheng

Publication type:

Article

Anti-aggregant tau mutant promotes neurogenesis.

Published in:

Molecular Neurodegeneration, 2017, v. 12, p. 1, doi. 10.1186/s13024-017-0230-8

By:

Joseph, Maria;
Anglada-Huguet, Marta;
Paesler, Katharina;
Mandelkow, Eckhard;
Eva-Maria, Mandelkow

Publication type:

Article

Abnormal dendritic calcium activity and synaptic depotentiation occur early in a mouse model of Alzheimer's disease.

Published in:

Molecular Neurodegeneration, 2017, v. 12, p. 1, doi. 10.1186/s13024-017-0228-2

By:

Yang Bai;
Miao Li;
Yanmei Zhou;
Lei Ma;
Qian Qiao;
Wanling Hu;
Wei Li;
Wills, Zachary Patrick;
Wen-Biao Gan

Publication type:

Article

A validated antibody panel for the characterization of tau post-translational modifications.

Published in:

Molecular Neurodegeneration, 2017, v. 12, p. 1, doi. 10.1186/s13024-017-0229-1

By:

Ercan, Ebru;
Eid, Sameh;
Weber, Christian;
Kowalski, Alexandra;
Bichmann, Maria;
Behrendt, Annika;
Matthes, Frank;
Krauss, Sybille;
Reinhardt, Peter;
Fulle, Simone;
Ehrnhoefer, Dagmar E.

Publication type:

Article

NADPH oxidases in Parkinson's disease: a systematic review.

Published in:

Molecular Neurodegeneration, 2017, v. 12, p. 1, doi. 10.1186/s13024-017-0225-5

By:

Belarbi, Karim;
Cuvelier, Elodie;
Destée, Alain;
Gressier, Bernard;
Chartier-Harlin, Marie-Christine

Publication type:

Article

Advances, challenges and future directions for stem cell therapy in amyotrophic lateral sclerosis.

Published in:

Molecular Neurodegeneration, 2017, v. 12, p. 1, doi. 10.1186/s13024-017-0227-3

By:

Yuri Ciervo;
Ke Ning;
Xu Jun;
Shaw, Pamela J.;
Mead, Richard J.

Publication type:

Article

The Trojan horse - neuroinflammatory impact of T cells in neurodegenerative diseases.

Published in:

Molecular Neurodegeneration, 2017, v. 12, p. 1, doi. 10.1186/s13024-017-0222-8

By:

Sommer, Annika;
Winner, Beate;
Prots, Iryna

Publication type:

Article

Fibroblast bioenergetics to classify amyotrophic lateral sclerosis patients.

Published in:

Molecular Neurodegeneration, 2017, v. 12, p. 1, doi. 10.1186/s13024-017-0217-5

By:

Konrad, Csaba;
Hibiki Kawamata;
Bredvik, Kirsten G.;
Arreguin, Andrea J.;
Cajamarca, Steven A.;
Hupf, Jonathan C.;
Ravits, John M.;
Miller, Timothy M.;
Maragakis, Nicholas J.;
Hales, Chadwick M.;
Glass, Jonathan D.;
Gross, Steven;
Hiroshi Mitsumoto;
Manfredi, Giovanni

Publication type:

Article

Proteomic profiling of neuronal mitochondria reveals modulators of synaptic architecture.

Published in:

Molecular Neurodegeneration, 2017, v. 12, p. 1, doi. 10.1186/s13024-017-0221-9

By:

Graham, Laura C.;
Eaton, Samantha L.;
Brunton, Paula J.;
Atrih, Abdelmadjid;
Smith, Colin;
Lamont, Douglas J.;
Gillingwater, Thomas H.;
Pennetta, Giuseppa;
Skehel, Paul;
Wishart, Thomas M.

Publication type:

Article

Haplotype-specific MAPT exon 3 expression regulated by common intronic polymorphisms associated with Parkinsonian disorders.

Published in:

Molecular Neurodegeneration, 2017, v. 12, p. 1, doi. 10.1186/s13024-017-0224-6

By:

Mang Ching Lai;
Bechy, Anne-Laure;
Denk, Franziska;
Collins, Emma;
Gavriliouk, Maria;
Zaugg, Judith B.;
Ryan, Brent J.;
Wade-Martins, Richard;
Caffrey, Tara M.

Publication type:

Article

Modulating the catalytic activity of AMPK has neuroprotective effects against α-synuclein toxicity.

Published in:

Molecular Neurodegeneration, 2017, v. 12, p. 1, doi. 10.1186/s13024-017-0220-x

By:

Bobela, Wojciech;
Nazeeruddin, Sameer;
Knott, Graham;
Aebischer, Patrick;
Schneider, Bernard L.

Publication type:

Article

TREM2 deficiency exacerbates tau pathology through dysregulated kinase signaling in a mouse model of tauopathy.

Published in:

Molecular Neurodegeneration, 2017, v. 12, p. 1, doi. 10.1186/s13024-017-0216-6

By:

Bemiller, Shane M.;
McCray, Tyler J.;
Allan, Kevin;
Formica, Shane V.;
Guixiang Xu;
Wilson$5, Gina;
Kokiko-Cochran, Olga N.;
Crish, Samuel D.;
Lasagna-Reeves, Cristian A.;
Ransohoff, Richard M.;
Landreth, Gary E.;
Lamb, Bruce T.

Publication type:

Article

Together JUN and DDIT3 (CHOP) control retinal ganglion cell death after axonal injury.

Published in:

Molecular Neurodegeneration, 2017, v. 12, p. 1, doi. 10.1186/s13024-017-0214-8

By:

Syc-Mazurek, Stephanie B.;
Fernandes, Kimberly A.;
Wilson, Michael P.;
Shrager, Peter;
Libby, Richard T.

Publication type:

Article

Aβ accumulation causes MVB enlargement and is modelled by dominant negative VPS4A.

Published in:

Molecular Neurodegeneration, 2017, v. 12, p. 1, doi. 10.1186/s13024-017-0203-y

By:

Willén, Katarina;
Edgar, James R.;
Takafumi Hasegawa;
Nobuyuki Tanaka;
Futter, Clare E.;
Gouras, Gunnar K.

Publication type:

Article

Depletion of adult neurogenesis exacerbates cognitive deficits in Alzheimer's disease by compromising hippocampal inhibition.

Published in:

Molecular Neurodegeneration, 2017, v. 12, p. 1, doi. 10.1186/s13024-017-0207-7

By:

Hollands, Carolyn;
Tobin, Matthew Kyle;
Hsu, Michael;
Musaraca, Kianna;
Mishra, Rachana;
Lazarov, Orly;
Tzong-Shiue Yu;
Kernie, Steven G.

Publication type:

Article

Gad67 haploinsufficiency reduces amyloid pathology and rescues olfactory memory deficits in a mouse model of Alzheimer's disease.

Published in:

Molecular Neurodegeneration, 2017, v. 12, p. 1, doi. 10.1186/s13024-017-0213-9

By:

Yue Wang;
Zheng Wu;
Yu-Ting Bai;
Gang-Yi Wu;
Gong Chen

Publication type:

Article

Lysosomal processing of progranulin.

Published in:

Molecular Neurodegeneration, 2017, v. 12, p. 1, doi. 10.1186/s13024-017-0205-9

By:

Xiaolai Zhou;
Paushter, Daniel H.;
Tuancheng Feng;
Lirong Sun;
Reinheckel, Thomas;
Fenghua Hu

Publication type:

Article

Quantification of plasma phosphorylated tau to use as a biomarker for brain Alzheimer pathology: pilot case-control studies including patients with Alzheimer’s disease and down syndrome.

Published in:

Molecular Neurodegeneration, 2017, v. 12, n. 1, p. 1, doi. 10.1186/s13024-017-0206-8

By:

Harutsugu Tatebe;
Takashi Kasai;
Takuma Ohmichi;
Yusuke Kishi;
Tomoshi Kakeya;
Masaaki Waragai;
Masaki Kondo;
Allsop, David;
Takahiko Tokuda

Publication type:

Article

The CNS in inbred transgenic models of 4-repeat Tauopathy develops consistent tau seeding capacity yet focal and diverse patterns of protein deposition.

Published in:

Molecular Neurodegeneration, 2017, v. 12, p. 1, doi. 10.1186/s13024-017-0215-7

By:

Eskandari-Sedighi, Ghazaleh;
Daude, Nathalie;
Gapeshina, Hristina;
Sanders, David W.;
Kamali-Jamil, Razieh;
Jing Yang;
Beipei Shi;
Wille, Holger;
Ghetti, Bernardino;
Diamond, Marc I.;
Janus, Christopher;
Westaway, David

Publication type:

Article

High-density lipoproteins suppress Aβ- induced PBMC adhesion to human endothelial cells in bioengineered vessels and in monoculture.

Published in:

Molecular Neurodegeneration, 2017, v. 12, p. 1, doi. 10.1186/s13024-017-0201-0

By:

Robert, Jérôme;
Button, Emily B.;
Stukas, Sophie;
Boyce, Guilaine K.;
Gibbs, Ebrima;
Cowan, Catherine M.;
Gilmour, Megan;
Wai Hang Cheng;
Soo, Sonja K.;
Brian Yuen;
Bahrabadi, Arvin;
Kevin Kang;
Kulic, Iva;
Francis, Gordon;
Cashman, Neil;
Wellington, Cheryl L.

Publication type:

Article

Hexokinases link DJ-1 to the PINK1/parkin pathway.

Published in:

Molecular Neurodegeneration, 2017, v. 12, p. 1, doi. 10.1186/s13024-017-0212-x

By:

Hauser, David N.;
Mamais, Adamantios;
Conti, Melissa M.;
Primiani, Christopher T.;
Kumaran, Ravindran;
Dillman, Allissa A.;
Langston, Rebekah G.;
Beilina, Alexandra;
Garcia, Joseph H.;
Diaz-Ruiz, Alberto;
Bernier, Michel;
Fiesel, Fabienne C.;
Xu Hou;
Springer, Wolfdieter;
Yan Li;
de Cabo, Rafael;
Cookson, Mark R.

Publication type:

Article

Blood hemoglobin A1c levels and amyotrophic lateral sclerosis survival.

Published in:

Molecular Neurodegeneration, 2017, v. 12, p. 1, doi. 10.1186/s13024-017-0211-y

By:

Qian-Qian Wei;
Yongping Chen;
Bei Cao;
Ru Wei Ou;
Lingyu Zhang;
Yanbing Hou;
Xiang Gao;
Huifang Shang

Publication type:

Article

Role of the sigma-1 receptor chaperone in rod and cone photoreceptor degenerations in a mouse model of retinitis pigmentosa.

Published in:

Molecular Neurodegeneration, 2017, v. 12, p. 1, doi. 10.1186/s13024-017-0202-z

By:

Huan Yang;
Yingmei Fu;
Xinying Liu;
Shahi, Pawan K.;
Mavlyutov, Timur A.;
Jun Li;
Annie Yao;
Guo, Steven Z.-W.;
Pattnaik, Bikash R.;
Lian-Wang Guo

Publication type:

Article

Prevention of C5aR1 signaling delays microglial inflammatory polarization, favors clearance pathways and suppresses cognitive loss.

Published in:

Molecular Neurodegeneration, 2017, v. 12, p. 1, doi. 10.1186/s13024-017-0210-z

By:

Hernandez, Michael X.;
Shan Jiang;
Cole, Tracy A.;
Shu-Hui Chu;
Fonseca, Maria I.;
Melody J. Fang;
Hohsfield, Lindsay A.;
Torres, Maria D.;
Green, Kim N.;
Wetsel, Rick A.;
Mortazavi, Ali;
Tenner, Andrea J.

Publication type:

Article

Whole blood gene expression and white matter Hyperintensities.

Published in:

Molecular Neurodegeneration, 2017, v. 12, p. 1, doi. 10.1186/s13024-017-0209-5

By:

Honghuang Lin;
Satizabal, Claudia;
Zhijun Xie;
Qiong Yang;
Tianxiao Huan;
Joehanes, Roby;
Chengping Wen;
Munson, Peter J.;
Beiser, Alexa;
Levy, Daniel;
Seshadri, Sudha

Publication type:

Article

The heat shock response in neurons and astroglia and its role in neurodegenerative diseases.

Published in:

Molecular Neurodegeneration, 2017, v. 12, p. 1, doi. 10.1186/s13024-017-0208-6

By:

Gil, Rebecca San;
Ooi, Lezanne;
Yerbury, Justin J.;
Ecroyd, Heath

Publication type:

Article

Absence of CX3CR1 impairs the internalization of Tau by microglia.

Published in:

Molecular Neurodegeneration, 2017, v. 12, p. 1, doi. 10.1186/s13024-017-0200-1

By:

Bolós, Marta;
Llorens-Martín, María;
Perea, Juan Ramón;
Jurado-Arjona, Jerónimo;
Rábano, Alberto;
Hernández, Félix;
Avila, Jesús

Publication type:

Article

Tau accumulation in the retina promotes early neuronal dysfunction and precedes brain pathology in a mouse model of Alzheimer's disease.

Published in:

Molecular Neurodegeneration, 2017, v. 12, p. 1, doi. 10.1186/s13024-017-0199-3

By:

Chiasseu, Marius;
Alarcon-Martinez, Luis;
Belforte, Nicolas;
Quintero, Heberto;
Dotigny, Florence;
Destroismaisons, Laurie;
Velde, Christine Vande;
Panayi, Fany;
Louis, Caroline;
Di Polo, Adriana

Publication type:

Article

Intranasal insulin reverts central pathology and cognitive impairment in diabetic mother offspring.

Published in:

Molecular Neurodegeneration, 2017, v. 12, p. 1, doi. 10.1186/s13024-017-0198-4

By:

Ramos-Rodriguez, Juan Jose;
Sanchez-Sotano, Daniel;
Doblas-Marquez, Alberto;
Infante-Garcia, Carmen;
Lubian-Lopez, Simon;
Garcia-Alloza, Monica

Publication type:

Article

The lysosomal protein cathepsin L is a progranulin protease.

Published in:

Molecular Neurodegeneration, 2017, v. 12, p. 1, doi. 10.1186/s13024-017-0196-6

By:

Lee, Chris W.;
Stankowski, Jeannette N.;
Jeannie Chew;
Cook, Casey N.;
Ying-Wai Lam;
Almeida, Sandra;
Carlomagno, Yari;
Kwok-Fai Lau;
Prudencio, Mercedes;
Fen-Biao Gao;
Bogyo, Matthew;
Dickson, Dennis W.;
Petrucelli, Leonard

Publication type:

Article

TREM2 in Neurodegenerative Diseases.

Published in:

Molecular Neurodegeneration, 2017, v. 12, p. 1, doi. 10.1186/s13024-017-0197-5

By:

Jay, Taylor R.;
von Saucken, Victoria E.;
Landreth, Gary E.

Publication type:

Article

A proteomic analysis of LRRK2 binding partners reveals interactions with multiple signaling components of the WNT/PCP pathway.

Published in:

Molecular Neurodegeneration, 2017, v. 12, p. 1, doi. 10.1186/s13024-017-0193-9

By:

Salašová, Alena;
Yokota, Chika;
Potěšil, David;
Zdráhal, Zbyněk;
Bryja, Vítězslav;
Arenas, Ernest

Publication type:

Article

TRPA1 channels promote astrocytic Ca<sup>2+</sup> hyperactivity and synaptic dysfunction mediated by oligomeric forms of amyloid-β peptide.

Published in:

Molecular Neurodegeneration, 2017, v. 12, p. 1, doi. 10.1186/s13024-017-0194-8

By:

Bosson, Anthony;
Paumier, Adrien;
Boisseau, Sylvie;
Jacquier-Sarlin, Muriel;
Buisson, Alain;
Albrieux, Mireille

Publication type:

Article

Toll-like receptor 4 stimulation with monophosphoryl lipid A ameliorates motor deficits and nigral neurodegeneration triggered by extraneuronal α- synucleinopathy.

Published in:

Molecular Neurodegeneration, 2017, v. 12, p. 1, doi. 10.1186/s13024-017-0195-7

By:

Venezia, Serena;
Refolo, Violetta;
Polissidis, Alexia;
Stefanis, Leonidas;
Wenning, Gregor K.;
Stefanova, Nadia

Publication type:

Article

Dissecting the role of non-coding RNAs in the accumulation of amyloid and tau neuropathologies in Alzheimer's disease.

Published in:

Molecular Neurodegeneration, 2017, v. 12, p. 1, doi. 10.1186/s13024-017-0191-y

By:

Patrick, Ellis;
Rajagopal, Sathyapriya;
Hon-Kit Andus Wong;
McCabe, Cristin;
Jishu Xu;
Tang, Anna;
Imboywa, Selina H.;
Schneider, Julie A.;
Pochet, Nathalie;
Krichevsky, Anna M.;
Chibnik, Lori B.;
Bennett, David A.;
De Jager, Philip L.

Publication type:

Article

Glial contributions to neurodegeneration in tauopathies.

Published in:

Molecular Neurodegeneration, 2017, v. 12, p. 1, doi. 10.1186/s13024-017-0192-x

By:

Leyns, Cheryl E. G.;
Holtzman, David M.

Publication type:

Article

Post translational changes to α-synuclein control iron and dopamine trafficking; a concept for neuron vulnerability in Parkinson's disease.

Published in:

Molecular Neurodegeneration, 2017, v. 12, p. 1, doi. 10.1186/s13024-017-0186-8

By:

Duce, James A.;
Wong, Bruce X.;
Durham, Hannah;
Devedjian, Jean-Christophe;
Smith, David P.;
Devos, David

Publication type:

Article

Targeting psychologic stress signaling pathways in Alzheimer's disease.

Published in:

Molecular Neurodegeneration, 2017, v. 12, p. 1, doi. 10.1186/s13024-017-0190-z

By:

Futch, Hunter S.;
Croft, Cara L.;
Truong, Van Q.;
Krause, Eric G.;
Golde, Todd E.

Publication type:

Article

Microglia limit the expansion of β-amyloid plaques in a mouse model of Alzheimer's disease.

Published in:

Molecular Neurodegeneration, 2017, v. 12, p. 1, doi. 10.1186/s13024-017-0188-6

By:

Ruohe Zhao;
Wanling Hu;
Julia Tsai;
Wei Li;
Wen-Biao Gan

Publication type:

Article

A C9ORF72 BAC mouse model recapitulates key epigenetic perturbations of ALS/FTD.

Published in:

Molecular Neurodegeneration, 2017, v. 12, p. 1, doi. 10.1186/s13024-017-0185-9

By:

Esanov, Rustam;
Cabrera, Gabriela Toro;
Andrade, Nadja S.;
Gendron, Tania F.;
Brown Jr., Robert H.;
Benatar, Michael;
Wahlestedt, Claes;
Mueller, Christian;
Zeier, Zane

Publication type:

Article

Autoimmune antibody decline in Parkinson's disease and Multiple System Atrophy; a step towards immunotherapeutic strategies.

Published in:

Molecular Neurodegeneration, 2017, v. 12, p. 1, doi. 10.1186/s13024-017-0187-7

By:

Brudek, Tomasz;
Winge, Kristian;
Folke, Jonas;
Christensen, Søren;
Fog, Karina;
Pakkenberg, Bente;
Pedersen, Lars Østergaard

Publication type:

Article

Presenilins regulate synaptic plasticity and mitochondrial calcium homeostasis in the hippocampal mossy fiber pathway.

Published in:

Molecular Neurodegeneration, 2017, v. 12, p. 1, doi. 10.1186/s13024-017-0189-5

By:

Sang Hun Lee;
Lutz, David;
Mossalam, Mohanad;
Bolshakov, Vadim Y.;
Frotscher, Michael;
Shen, Jie

Publication type:

Article

Intrastriatal injection of α-synuclein can lead to widespread synucleinopathy independent of neuroanatomic connectivity.

Published in:

Molecular Neurodegeneration, 2017, v. 12, p. 1, doi. 10.1186/s13024-017-0182-z

By:

Sorrentino, Zachary A.;
Brooks, Mieu M. T.;
Hudson III, Vincent;
Rutherford, Nicola J.;
Golde, Todd E.;
Giasson, Benoit I.;
Chakrabarty, Paramita

Publication type:

Article

Phosphorylation of tau at Y18, but not taufyn binding, is required for tau to modulate NMDA receptor-dependent excitotoxicity in primary neuronal culture.

Published in:

Molecular Neurodegeneration, 2017, v. 12, p. 1, doi. 10.1186/s13024-017-0176-x

By:

Takashi Miyamoto;
Stein, Liana;
Thomas, Reuben;
Djukic, Biljana;
Taneja, Praveen;
Knox, Joseph;
Vossel, Keith;
Mucke, Lennart

Publication type:

Article

Microglia-derived IL-1β promotes chemokine expression by Müller cells and RPE in focal retinal degeneration.

Published in:

Molecular Neurodegeneration, 2017, v. 12, p. 1, doi. 10.1186/s13024-017-0175-y

By:

Natoli, Riccardo;
Fernando, Nilisha;
Madigan, Michele;
Chu-Tan, Joshua A.;
Valter, Krisztina;
Provis, Jan;
Rutar, Matt

Publication type:

Article