Works in Chemical Biology & Drug Design, 2012, Vol 79, Issue 4

Results: 26

Design and Synthesis of N-Substituted Indazole-3-Carboxamides as Poly(ADP-ribose)polymerase-1 (PARP-1) Inhibitors<sup>†</sup>.

Published in:

Chemical Biology & Drug Design, 2012, v. 79, n. 4, p. 488, doi. 10.1111/j.1747-0285.2011.01302.x

By:

Patel, Maulik R.;
Pandya, Kashyap G.;
Lau-Cam, Cesar A.;
Singh, Satyakam;
Pino, Maria A.;
Billack, Blase;
Degenhardt, Kurt;
Talele, Tanaji T.

Publication type:

Article

Selective Flexibility of Side-Chain Residues Improves VEGFR-2 Docking Score using AutoDock Vina.

Published in:

Chemical Biology & Drug Design, 2012, v. 79, n. 4, p. 530, doi. 10.1111/j.1747-0285.2011.01313.x

By:

Abreu, Rui M. V.;
Froufe, Hugo J. C.;
Queiroz, Maria-João R. P.;
Ferreira, Isabel C. F. R.

Publication type:

Article

Issue Information.

Published in:: Chemical Biology & Drug Design, 2012, v. 79, n. 4, p. i, doi. 10.1111/j.1747-0285.2011.01353.x
Publication type:: Article

Transport Characteristics of Endomorphin-2 Analogues in Brain Capillary Endothelial Cells.

Published in:

Chemical Biology & Drug Design, 2012, v. 79, n. 4, p. 507, doi. 10.1111/j.1747-0285.2011.01306.x

By:

Mallareddy, Jayapal Reddy;
Tóth, Géza;
Fazakas, Csilla;
Molnár, Judit;
Nagyőszi, Péter;
Lipkowski, Andrzej W.;
Krizbai, István A.;
Wilhelm, Imola

Publication type:

Article

1-Benzyl-1,2,3,4-Tetrahydro-β-Carboline as Channel Blocker of N-Methyl- d-Aspartate Receptors.

Published in:

Chemical Biology & Drug Design, 2012, v. 79, n. 4, p. 594, doi. 10.1111/j.1747-0285.2012.01317.x

By:

Espinoza-Moraga, Marlene;
Caballero, Julio;
Gaube, Friedemann;
Winckler, Thomas;
Santos, Leonardo S.

Publication type:

Article

Insight into Selectivity of Peptidomimetic Inhibitors with Modified Statine Core for Plasmepsin II of Plasmodium falciparum over Human Cathepsin D.

Published in:

Chemical Biology & Drug Design, 2012, v. 79, n. 4, p. 411, doi. 10.1111/j.1747-0285.2011.01276.x

By:

Dali, Brice;
Keita, Melalie;
Megnassan, Eugene;
Frecer, Vladimir;
Miertus, Stanislav

Publication type:

Article

A Modeling Study for Structure Features of β- N-acetyl-D-hexosaminidase from Ostrinia furnacalis and its Novel Inhibitor Allosamidin: Species Selectivity and Multi-Target Characteristics.

Published in:

Chemical Biology & Drug Design, 2012, v. 79, n. 4, p. 572, doi. 10.1111/j.1747-0285.2011.01301.x

By:

Wang, Yanli;
Liu, Tian;
Yang, Qing;
Li, Zhong;
Qian, Xuhong

Publication type:

Article

Computational Design of Peptide Inhibitor Based on Modifications of Proregion from Plutella xylostella Midgut Trypsin.

Published in:

Chemical Biology & Drug Design, 2012, v. 79, n. 4, p. 583, doi. 10.1111/j.1747-0285.2011.01312.x

By:

Jitonnom, Jitrayut;
Lomthaisong, Khemika;
Lee, Vannajan S.

Publication type:

Article

Antiplasmodial activity of steroidal chalcones: evaluation of their effect on hemozoin synthesis and the new permeation pathway of Plasmodium falciparum-infected erythrocyte membrane.

Published in:

Chemical Biology & Drug Design, 2012, v. 79, n. 4, p. 610, doi. 10.1111/j.1747-0285.2012.01323.x

By:

Sisodia, Brijesh S.;
Negi, Arvind S.;
Darokar, Mahendra P.;
Dwivedi, Upendra N.;
Khanuja, Suman P. S.

Publication type:

Article

Evaluation of Antiproliferative Effect of N-(alkyladamantyl)phthalimides In vitro.

Published in:

Chemical Biology & Drug Design, 2012, v. 79, n. 4, p. 497, doi. 10.1111/j.1747-0285.2011.01305.x

By:

Horvat, Margareta;
Uzelac, Lidija;
Marjanović, Marko;
Cindro, Nikola;
Franković, Oliver;
Mlinarić-Majerski, Kata;
Kralj, Marijeta;
Basarić, Nikola

Publication type:

Article

Synthesis of Novel Nalidixic Acid-Based 1,3,4-Thiadiazole and 1,3,4-Oxadiazole Derivatives as Potent Antibacterial Agents.

Published in:

Chemical Biology & Drug Design, 2012, v. 79, n. 4, p. 384, doi. 10.1111/j.1747-0285.2011.01316.x

By:

Aggarwal, Nisha;
Kumar, Rajesh;
Dureja, Prem;
Khurana, Jitender Mohan

Publication type:

Article

Virtual Design of Chemical Penetration Enhancers for Transdermal Drug Delivery.

Published in:

Chemical Biology & Drug Design, 2012, v. 79, n. 4, p. 478, doi. 10.1111/j.1747-0285.2011.01293.x

By:

Golla, Sharath;
Neely, Brian J.;
Whitebay, Eric;
Madihally, Sundar;
Robinson, Robert L.;
Gasem, Khaled A. M.

Publication type:

Article

Quantum Chemical QSAR Models to Distinguish Between Inhibitory Activities of Sulfonamides Against Human Carbonic Anhydrases I and II and Bovine IV Isozymes.

Published in:

Chemical Biology & Drug Design, 2012, v. 79, n. 4, p. 514, doi. 10.1111/j.1747-0285.2011.01309.x

By:

Deeb, Omar;
Goodarzi, Mohammad;
Khadikar, Padmaker V.

Publication type:

Article

Synthesis and Pharmacological Evaluation of Novel Arginine Analogs as Potential Inhibitors of Acetylcholine-Induced Relaxation in Rat Thoracic Aortic Rings.

Published in:

Chemical Biology & Drug Design, 2012, v. 79, n. 4, p. 459, doi. 10.1111/j.1747-0285.2011.01286.x

By:

Jain, Manish;
Barthwal, Manoj Kumar;
Haq, Wahajul;
Katti, Seturam B.;
Dikshit, Madhu

Publication type:

Article

Computational Chemical Biology: Identification of Small Molecular Probes that Discriminate between Members of Target Protein Families.

Published in:

Chemical Biology & Drug Design, 2012, v. 79, n. 4, p. 369, doi. 10.1111/j.1747-0285.2011.01297.x

By:

Dimova, Dilyana;
Bajorath, Jürgen

Publication type:

Article

Synthesis and Antitumor Activity of Dehydroepiandrosterone Derivatives on Es-2, A549, and HepG2 Cells in vitro.

Published in:

Chemical Biology & Drug Design, 2012, v. 79, n. 4, p. 523, doi. 10.1111/j.1747-0285.2011.01311.x

By:

Liu, Xue-Kun;
Ye, Bai-Jun;
Wu, Yan;
Nan, Ji-Xing;
Lin, Zhen-Hua;
Piao, Hu-Ri

Publication type:

Article

A Novel Pharmacophore Model to Identify Leads for Simultaneous Inhibition of Anti-coagulation and Anti-inflammatory Activities of Snake Venom Phospholipase A<sub>2</sub>.

Published in:

Chemical Biology & Drug Design, 2012, v. 79, n. 4, p. 431, doi. 10.1111/j.1747-0285.2011.01281.x

By:

Wadood, Abdul;
Ali, Syed Abid;
Sattar, Rabia;
Lodhi, Muhammad Arif;
Ul-Haq, Zaheer

Publication type:

Article

Synthesis and Hypolipidemic Activity of Novel 2-(4-(2-Amino-6-(4-Substituted Phenyl) Pyrimidin-4-yl)-2-Substituted Phenoxy) Acetic Acid Derivatives.

Published in:

Chemical Biology & Drug Design, 2012, v. 79, n. 4, p. 548, doi. 10.1111/j.1747-0285.2012.01319.x

By:

Mokale, Santosh N.;
Shete, Maheshwari T.;
Shaikh, Sameer I.;
Shinde, Devanand B.

Publication type:

Article

DFT-based QSAR Models to Predict the Antimycobacterial Activity of Chalcones.

Published in:

Chemical Biology & Drug Design, 2012, v. 79, n. 4, p. 553, doi. 10.1111/j.1747-0285.2011.01289.x

By:

Barua, Nilakshi;
Sarmah, Pubalee;
Hussain, Iftikar;
Deka, Ramesh C.;
Buragohain, Alak K.

Publication type:

Article

In Silico Characterization of Atypical Kinase PFD0975w from Plasmodium Kinome: A Suitable Target For Drug Discovery.

Published in:

Chemical Biology & Drug Design, 2012, v. 79, n. 4, p. 600, doi. 10.1111/j.1747-0285.2012.01321.x

By:

Trivedi, Vishal;
Nag, Swagata

Publication type:

Article

Understanding the Physical Interactions in the FGF21/FGFR/β-Klotho Complex: Structural Requirements and Implications in FGF21 Signaling.

Published in:

Chemical Biology & Drug Design, 2012, v. 79, n. 4, p. 398, doi. 10.1111/j.1747-0285.2012.01325.x

By:

Yie, Junming;
Wang, Wei;
Deng, Liying;
Tam, Lei-Ting;
Stevens, Jennitte;
Chen, Michelle M.;
Li, Yang;
Xu, Jing;
Lindberg, Richard;
Hecht, Randy;
Véniant, Murielle;
Chen, Ching;
Wang, Minghan

Publication type:

Article

3D-QSAR and Molecular Docking Studies on 3-Anilino-4-Arylmaleimide Derivatives as Glycogen Synthase Kinase-3β Inhibitors.

Published in:

Chemical Biology & Drug Design, 2012, v. 79, n. 4, p. 560, doi. 10.1111/j.1747-0285.2011.01291.x

By:

Akhtar, Mymoona;
Bharatam, Prasad V.

Publication type:

Article

Conformational Preferences of Proline Derivatives Incorporated into Vasopressin Analogues: NMR and Molecular Modelling Studies.

Published in:

Chemical Biology & Drug Design, 2012, v. 79, n. 4, p. 535, doi. 10.1111/j.1747-0285.2012.01318.x

By:

Sikorska, Emilia;
Sobolewski, Dariusz;
Kwiatkowska, Anna

Publication type:

Article

QSAR Study of 4-Aryl-4 H-Chromenes as a New Series of Apoptosis Inducers Using Different Chemometric Tools.

Published in:

Chemical Biology & Drug Design, 2012, v. 79, n. 4, p. 442, doi. 10.1111/j.1747-0285.2011.01284.x

By:

Khoshneviszadeh, Mehdi;
Edraki, Najmeh;
Miri, Ramin;
Foroumadi, Alireza;
Hemmateenejad, Bahram

Publication type:

Article

Synthesis of Potent Dishevelled PDZ Domain Inhibitors Guided by Virtual Screening and NMR Studies.

Published in:

Chemical Biology & Drug Design, 2012, v. 79, n. 4, p. 376, doi. 10.1111/j.1747-0285.2011.01295.x

By:

Shan, Jufang;
Zhang, Xinxin;
Bao, Ju;
Cassell, Robert;
Zheng, Jie J.

Publication type:

Article

MCR Synthesis of Praziquantel Derivatives.

Published in:

Chemical Biology & Drug Design, 2012, v. 79, n. 4, p. 470, doi. 10.1111/j.1747-0285.2011.01288.x

By:

Liu, Haixia;
William, Samia;
Herdtweck, Eberhardt;
Botros, Sanaa;
Dömling, Alexander

Publication type:

Article