Works matching IS 17456150 AND DT 2025 AND VI 20 AND IP 1

Results: 73

Multimodal deep learning for predicting neoadjuvant treatment outcomes in breast cancer: a systematic review.

Published in:

Biology Direct, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13062-025-00661-8

By:

Krasniqi, Eriseld;
Filomeno, Lorena;
Arcuri, Teresa;
Ferretti, Gianluigi;
Gasparro, Simona;
Fulvi, Alberto;
Roselli, Arianna;
D'Onofrio, Loretta;
Pizzuti, Laura;
Barba, Maddalena;
Maugeri-Saccà, Marcello;
Botti, Claudio;
Graziano, Franco;
Puccica, Ilaria;
Cappelli, Sonia;
Pelle, Fabio;
Cavicchi, Flavia;
Villanucci, Amedeo;
Paris, Ida;
Calabrò, Fabio

Publication type:

Article

SPI1 upregulated LILRB2 to enhance the immunosuppressive phenotype of LPS-tolerant macrophages by inhibiting TLR8-mediated MyD88/NF-κB signaling.

Published in:

Biology Direct, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13062-025-00669-0

By:

Bai, Ruojing;
Guo, Jun

Publication type:

Article

Phosphorylation-stabilized CRTC1 cooperates with CBP and androgen receptor to transactivate AMH expression and drive polycystic ovary syndrome.

Published in:

Biology Direct, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13062-025-00665-4

By:

Ke, Yunmei;
Zheng, Jinyan;
Zhang, Jinman;
Tang, Dan;
Yang, Qin;
Zhao, Han;
Zhu, Caifen;
Zhang, Yan

Publication type:

Article

Autophagy is influenced by vitamin D3 level in people with HIV-1.

Published in:

Biology Direct, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13062-025-00660-9

By:

Casetti, Rita;
Ciccosanti, Fabiola;
Lamsira, Harpreet Kaur;
Pinnetti, Carmela;
Mazzotta, Valentina;
Ciolfi, Serena;
Sacchi, Alessandra;
Amendola, Alessandra;
Ippolito, Giuseppe;
Piacentini, Mauro;
Nardacci, Roberta

Publication type:

Article

Estrogen receptor alpha dynamics and plasticity during endocrine resistance.

Published in:

Biology Direct, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13062-025-00653-8

By:

Sivasailam, Aswathy;
Kumar, Kiran S.;
Jayaprasad, Aparna Geetha;
Jancy, Shine Varghese;
Harikumar, Ashwathi;
Unnikrishnan, P. S.;
Sivakumar, K. C.;
Tiffee, P. J. Jain;
Halikar, Aman Munirpasha;
Nithin, S. S.;
Pillai, Prakash R.;
Tiwari, Shivanshu Kumar;
Sanjeev, Vishnu S.;
Surabhi, A. V.;
Santhoshkumar, T. R.

Publication type:

Article

A multi-omics exploration of PPARG activation in colon cancer: kinases featuring a PPRE sequence within regulatory regions.

Published in:

Biology Direct, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13062-025-00654-7

By:

Saha, Pritha;
Ravanan, Palaniyandi;
Talwar, Priti

Publication type:

Article

Affibodies as valuable tool to prevent β2m aggregation under lysosomal-like conditions.

Published in:

Biology Direct, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13062-025-00659-2

By:

Cristina, Visentin;
Giulia, Rizzi;
Yin, Wen;
Mathilde, Hotot;
Dipambita, Roy;
Torbjörn, Gräslund;
Riccardo, Capelli;
Stefano, Ricagno

Publication type:

Article

Macrophage Notch1 drives septic cardiac dysfunction by impairing mitophagy and promoting NLRP3 activation.

Published in:

Biology Direct, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13062-025-00657-4

By:

Zheng, Yanjun;
Lin, Jingrong;
Wan, Guoqing;
Gu, Xuefeng;
Ma, Jian

Publication type:

Article

LDHA-mediated YAP lactylation promotes the tumor progression of hepatocellular carcinoma by inducing YAP dephosphorylation and activation.

Published in:

Biology Direct, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13062-025-00655-6

By:

Wei, Xiaoyong;
Zou, Long;
Huang, Yanqing;
Qiu, Chuan;
Cheng, Guang;
Chen, Ye;
Rao, Jun

Publication type:

Article

scE2EGAE: enhancing single-cell RNA-Seq data analysis through an end-to-end cell-graph-learnable graph autoencoder with differentiable edge sampling.

Published in:

Biology Direct, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13062-025-00616-z

By:

Wang, Shuo;
Liu, Yuanning;
Zhang, Hao;
Liu, Zhen

Publication type:

Article

Gliadin-dependent UPR induction directly triggers the expression of TG2 and pro-inflammatory cytokines, dysregulates intestinal permeability, and reduces CFTR expression in intestinal epithelial cells of celiac disease patients.

Published in:

Biology Direct, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13062-025-00644-9

By:

Monzani, Romina;
Gagliardi, Mara;
Saverio, Valentina;
Clemente, Nausicaa;
Monzani, Alice;
Rabbone, Ivana;
Nigrelli, Francesca;
Pellizzaro, Samuele;
Ferrario, Emanuele;
Saettone, Silvia;
Pagano, Nico;
De Leo, Luigina;
Lim, Dmitry;
Sblattero, Daniele;
Corazzari, Marco

Publication type:

Article

Utilizing liquid-liquid biopolymer regulators to predict the prognosis and drug sensitivity of hepatocellular carcinoma.

Published in:

Biology Direct, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13062-025-00592-4

By:

Li, Jianhao;
Chen, Han;
Bai, Lang;
Tang, Hong

Publication type:

Article

Boanmycin overcomes bortezomib resistance by inducing DNA damage and endoplasmic reticulum functional impairment in multiple myeloma.

Published in:

Biology Direct, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13062-024-00590-y

By:

Wang, Jin-Xing;
Zhang, Ling;
Zhang, Peng-Wei;
Yuan, Luo-Wei;
Jiang, Jian;
Cheng, Xiao-Hui;
Zhu, Wei;
Lei, Yong;
Tian, Fa-Qing

Publication type:

Article

Mechanism of LINC01018/miR-182-5p/Rab27B in the immune escape through PD-L1-mediated CD8+ T cell suppression in glioma.

Published in:

Biology Direct, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13062-025-00651-w

By:

Hu, Su;
Chen, Guoshuo;
Luo, Aiping;
Zhao, Hailin;
Li, Dan;
Peng, Biao;
Du, Jike;
Luo, Dongdong

Publication type:

Article

Allosteric modulation of Grb2 drives ligand-dependent signal responses.

Published in:

Biology Direct, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13062-025-00656-5

By:

Di Felice, Mariana;
Rolfi, Lucrezia Romana;
Toso, Julian;
Pennacchietti, Valeria;
Ventura, Eduarda S.;
Toto, Angelo;
Tramutola, Antonella;
Gianni, Stefano

Publication type:

Article

Early-stage administration of hydroxytyrosol extends lifespan and delays aging in C. elegans.

Published in:

Biology Direct, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13062-025-00634-x

By:

Du, Nannan;
Song, Lishuo;
Yang, Ruigang;
Liu, Kexin;
Niu, Zubiao;
Zhang, Zhanfeng;
Sun, Qiang

Publication type:

Article

Elucidation of short linear motif-based interactions of the MIT and rhodanese domains of the ubiquitin-specific protease 8.

Published in:

Biology Direct, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13062-025-00638-7

By:

Konstantinou, Aimiliani;
Varga, Julia K.;
Córdova-Pérez, Alicia;
Simonetti, Leandro;
Gomez-Lucas, Lidia;
Schueler-Furman, Ora;
Davey, Norman E.;
Kulathu, Yogesh;
Ivarsson, Ylva

Publication type:

Article

Prmt1-mediated methylation regulates Ncoa4 stability to transactivate Adamts genes and promote bone extracellular matrix degradation in chronic hematogenous osteomyelitis.

Published in:

Biology Direct, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13062-025-00652-9

By:

Chen, Xun;
Duan, Ning;
Zhang, Wentao;
Song, Tao;
Cong, Fei

Publication type:

Article

Identification of M2 macrophage-related genes associated with diffuse large B-cell lymphoma via bioinformatics and machine learning approaches.

Published in:

Biology Direct, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13062-025-00649-4

By:

Zhang, Jiayi;
Jia, Zhixiang;
Zhang, Jiahui;
Mu, Xiaohui;
Ai, Limei

Publication type:

Article

Integrating machine learning models with multi-omics analysis to decipher the prognostic significance of mitotic catastrophe heterogeneity in bladder cancer.

Published in:

Biology Direct, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13062-025-00650-x

By:

Dai, Haojie;
Yu, Zijie;
Zhao, You;
Jiang, Ke;
Hang, Zhenyu;
Huang, Xin;
Ma, Hongxiang;
Wang, Li;
Li, Zihao;
Wu, Ming;
Fan, Jun;
Luo, Weiping;
Qin, Chao;
Zhou, Weiwen;
Nie, Jun

Publication type:

Article

The role of IGF2BP2 in macrophage-mediated NLRP3 inflammasome activation in the pathogenesis of dry AMD.

Published in:

Biology Direct, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13062-025-00648-5

By:

Zhao, Yuqing;
Zhang, Yu;
Li, Junfang;
Zhang, Yifei;
Qu, Yi

Publication type:

Article

Topological determinants in protein folding dynamics: a comparative analysis of metamorphic proteins.

Published in:

Biology Direct, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13062-025-00642-x

By:

Toso, Julian;
Pennacchietti, Valeria;
Di Felice, Mariana;
Ventura, Eduarda S.;
Toto, Angelo;
Gianni, Stefano

Publication type:

Article

AQP5 trafficking is regulated by its C-terminal tail and interaction with prolactin-inducible protein.

Published in:

Biology Direct, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13062-025-00647-6

By:

D'Agostino, Claudia;
Zindy, Egor;
Conrard, Louise;
Takkal, Amel;
Gregoire, Françoise;
Bolaky, Nargis;
Törnroth-Horsefield, Susanna;
Perret, Jason;
Delporte, Christine

Publication type:

Article

L-741626 inhibits hepatocellular carcinoma progression by targeting Ref-1 to suppress MAPK/ERK signalling pathway activity.

Published in:

Biology Direct, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13062-025-00624-z

By:

Jin, Shuiling;
Zhao, Qi;
Sun, Xiao;
Su, Jinsong;
Wang, Peiwen;
Li, Peixian;
Guo, Jing;
Zhang, Yibing;
Zong, Hong;
Gan, Xiaoli

Publication type:

Article

Colon cancer exosome-associated HSP90B1 initiates pre-metastatic niche formation in the liver by polarizing M1 macrophage into M2 phenotype.

Published in:

Biology Direct, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13062-025-00623-0

By:

Li, ShuJie;
Fu, Xue;
Ning, Deng;
Liu, QiuMeng;
Zhao, JunFang;
Cheng, Qi;
Chen, XiaoPing;
Jiang, Li

Publication type:

Article

Lipidome atlas of p53 mutant variants in pancreatic cancer.

Published in:

Biology Direct, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13062-025-00635-w

By:

Cotton, Kian;
Comer, Charley;
Caporali, Sabrina;
Butera, Alessio;
Gurres, Stephanie;
Capradossi, Francesco;
D'Alessandro, Angelo;
Amelio, Ivano;
Niklison-Chirou, Maria Victoria

Publication type:

Article

Downregulation of PD-L1 expression by Wnt pathway inhibition to enhance PD-1 blockade efficacy in hepatocellular carcinoma.

Published in:

Biology Direct, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13062-025-00645-8

By:

Shao, Yu-Yun;
Wang, Han-Yu;
Hsu, Hung-Wei;
Wo, Rita Robin;
Cheng, Ann-Lii;
Hsu, Chih-Hung

Publication type:

Article

Functional and structural characterization of the human indolethylamine N-methyltransferase through fluorometric, thermal and computational docking analyses.

Published in:

Biology Direct, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13062-025-00632-z

By:

Ardini, Matteo;
Angelucci, Francesco;
Rea, Francesca;
Paluzzi, Luca;
Gabriele, Federica;
Palerma, Marta;
Di Leandro, Luana;
Ippoliti, Rodolfo;
Pitari, Giuseppina

Publication type:

Article

ELK4 induced upregulation of HOMER3 promotes the proliferation and metastasis in glioma via Wnt/β-catenin/EMT signaling pathway.

Published in:

Biology Direct, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13062-025-00643-w

By:

Wang, Furong;
Zhou, Hui;
Tian, Yu;
Wang, Xiaoling;
Huang, Youcai;
Tu, Yanyang;
Li, Liwen;
Zhen, Haining

Publication type:

Article

Deubiquitination of DNM1L by USP3 triggers the development and metastasis of gallbladder carcinoma.

Published in:

Biology Direct, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13062-025-00637-8

By:

Liang, Ruopeng;
Zhang, Xiaoxue;
Wu, Shitao;
Liu, Jing;
Zhai, Yunpeng;
Lin, Chaojie;
Wang, Zhenya;
Zhang, Yi;
Chen, Hao;
Zhu, Rongtao

Publication type:

Article

CAP1: a novel extracellular vesicle marker linked to endothelial senescence in atherosclerosis.

Published in:

Biology Direct, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13062-025-00646-7

By:

Hernandez, Ignacio;
Botana, Laura;
Diez-Mata, Javier;
Tesoro, Laura;
Jimenez-Guirado, Beatriz;
Gonzalez-Cucharero, Claudia;
Alcharani, Nunzio;
Zamorano, Jose Luis;
Saura, Marta;
Zaragoza, Carlos

Publication type:

Article

Macrophage-derived SPP1 exacerbate myocardial injury by interacting with fibroblasts in viral myocarditis.

Published in:

Biology Direct, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13062-025-00621-2

By:

Duan, Xiuyun;
Zhang, Li;
Liu, Keyu;
Guo, Kaiyin;
You, Yingnan;
Jia, Hailin;
Zhou, Shan;
Han, Bo

Publication type:

Article

Large-scale bulk and single-cell RNA sequencing combined with machine learning reveals glioblastoma-associated neutrophil heterogeneity and establishes a VEGFA+ neutrophil prognostic model.

Published in:

Biology Direct, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13062-025-00640-z

By:

Yang, Yufan;
Liu, Ziyuan;
Wang, Zhongliang;
Fu, Xiang;
Li, Zhiyong;
Li, Jianlong;
Xu, Zhongyuan;
Cen, Bohong

Publication type:

Article

Plasma N-Glycoproteomics in monozygotic twin pairs discordant for body mass index reveals an obesity signature related to inflammation and iron metabolism.

Published in:

Biology Direct, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13062-025-00609-y

By:

Muniandy, Maheswary;
Joenväärä, Sakari;
van der Kolk, Birgitta W.;
Tohmola, Tiialotta;
Haltia, Hanna;
Saari, Sina;
Hakkarainen, Antti;
Lundbom, Jesper;
Kuula, Juho;
Groop, Per-Henrik;
Kaprio, Jaakko;
Heinonen, Sini;
Renkonen, Risto;
Pietiläinen, Kirsi H.

Publication type:

Article

GAMT facilitates tumor progression via inhibiting p53 in clear cell renal cell carcinoma.

Published in:

Biology Direct, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13062-025-00641-y

By:

Zheng, Bin;
Liu, Kan;
Feng, Ji;
Ouyang, Qing;
Jia, Tongyu;
Wang, Yaohui;
Tian, Shuo;
Chen, Xinran;
Cai, Tianwei;
Wen, Lequan;
Zhang, Xu;
Li, Xiubin;
Ma, Xin

Publication type:

Article

Exploring the mechanisms of PANoptosis in osteoarthritis and the therapeutic potential of andrographolide through bioinformatics and single-cell analysis.

Published in:

Biology Direct, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13062-025-00629-8

By:

Zhou, Daqian;
Luo, Yingjin;
Li, Fengjiang;
Liu, Tao;
Mei, Yongliang;
Li, Feilong;
Hou, Xianghan;
Fu, Zhijiang;
Liu, Zongchao

Publication type:

Article

Exploring the association between osteoporosis and kidney stones: a clinical to mechanistic translational study based on big data and bioinformatics.

Published in:

Biology Direct, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13062-025-00627-w

By:

Luo, Di;
Xie, Linguo;
Zhang, Jingdong;
Liu, Chunyu

Publication type:

Article

Dynamic single-cell transcriptomic reveals the cellular heterogeneity and a novel fibroblast subpopulation in laryngotracheal stenosis.

Published in:

Biology Direct, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13062-025-00639-6

By:

Liao, Ziwei;
Zheng, Yangyang;
Zhang, Mingjun;
Li, Xiaoyan;
Wang, Jing;
Xu, Hongming

Publication type:

Article

Identification of druggable targets in acute kidney injury by proteome- and transcriptome-wide Mendelian randomization and bioinformatics analysis.

Published in:

Biology Direct, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13062-025-00631-0

By:

Liu, Jiachen;
Zeng, Dianjie;
Wang, Yinhuai;
Deng, Fei;
Wu, Shuiqing;
Deng, Zebin

Publication type:

Article

c-Jun promotes neuroblastoma cell differentiation by inhibiting APC formation via CDC16 and reduces neuroblastoma malignancy.

Published in:

Biology Direct, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13062-025-00630-1

By:

Wang, Yunyun;
Huang, Jingjing;
Song, Zhenhua;
Zhang, Shuo;
Guo, Haojie;
Leng, Qi;
Fang, Na;
Ji, Shaoping;
Yang, Jian

Publication type:

Article

Circulating extracellular vesicles regulate ELAVL1 by delivering miR-133a-3p which affecting NLRP3 mRNA stability inhibiting PANoptosome formation.

Published in:

Biology Direct, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13062-025-00605-2

By:

Wang, Deliang;
Dai, Zheng;
Jiang, Lu;
Liu, Ke

Publication type:

Article

Prognostic and immunological implications of protein kinases in gastric cancer: a focus on hub gene ABL2 and its impact on the polarization of M2 macrophages.

Published in:

Biology Direct, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13062-025-00636-9

By:

Chen, Di;
Huang, Ju;
Yang, Aiming;
Xiong, Zhifan

Publication type:

Article

Single-cell RNA sequencing reveals a new mechanism of endothelial cell heterogeneity and healing in diabetic foot ulcers.

Published in:

Biology Direct, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13062-025-00628-9

By:

Zhao, Songyun;
Yu, Hua;
Li, Zihao;
Chen, Wanying;
Liu, Kaibo;
Dai, Hao;
Wang, Gaoyi;
Zhang, Zibing;
Xie, Jiaheng;
He, Yucang;
Li, Liqun

Publication type:

Article

Doxorubicin PK/PD modeling in multiple myeloma: towards in silico trials.

Published in:

Biology Direct, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13062-025-00626-x

By:

Andrean, Daniele;
Da Ros, Francesco;
Mazzucato, Mario;
Pedersen, Morten Gram;
Visentin, Roberto

Publication type:

Article

Dualistic role of ZEB1 and ZEB2 in tumor progression.

Published in:

Biology Direct, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13062-025-00604-3

By:

Parfenyev, Sergey E.;
Daks, Alexandra A.;
Shuvalov, Oleg Y.;
Fedorova, Olga A.;
Pestov, Nikolay B.;
Korneenko, Tatyana V.;
Barlev, Nickolai A.

Publication type:

Article

Differential growth and flowering capacity of tulip bulbs and the potential involvement of PHOSPHATIDYLETHANOLAMINE-BINDING PROTEINS (PEBPs).

Published in:

Biology Direct, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13062-025-00625-y

By:

Bellinazzo, Francesca;
Manders, Irene;
Heidemann, Bas;
Bolanos, Manuel Aguirre;
Stouten, Evelien;
Busscher, Jacqueline;
Abarca, Dolores;
van der Wal, Froukje;
Dornelas, Marcelo Carnier;
Angenent, Gerco C.;
Proveniers, Marcel;
Nijveen, Harm;
Immink, Richard G. H.

Publication type:

Article

The role of estrogen in the sex difference for the risk factors of heart failure with preserved ejection fraction.

Published in:

2025

By:

Du, Jun;
Liu, Jiaqi;
Wang, Xiaoya;
Wang, Xiaowu;
Ma, Yu;
Zhang, Sipan;
Li, Zilin;
Ma, Jipeng;
Liu, Jincheng

Publication type:

Literature Review

E3 ligase HERC5-catalyzed UGDH isgylation promotes SNAI1-mediated tumor metastasis and cisplatin resistance in oral squamous cell carcinoma.

Published in:

Biology Direct, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13062-025-00622-1

By:

Zhang, Xu;
Liu, Fayu;
Fang, Qigen;
Sun, Changfu;
Fan, Jie

Publication type:

Article

HOXB4/METTL7B cascade mediates malignant phenotypes of hepatocellular carcinoma through TKT m6A modification.

Published in:

Biology Direct, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13062-025-00620-3

By:

Guo, Enshuang;
Li, Lei;
Yang, Jiankun;
Zhou, Yongjian;
Bai, Lu;
Zhu, Weiwei;
Hu, Qiuyue;
Wang, Huifen;
Liu, Hongqiang

Publication type:

Article

Moving biology direct towards a new dimension.

Published in:

Biology Direct, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13062-025-00619-w

By:

Melino, Gerry

Publication type:

Article