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Ubiquitin recruiting chimera: more than just a PROTAC.
- Published in:
- Biology Direct, 2024, v. 19, n. 1, p. 1, doi. 10.1186/s13062-024-00497-8
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- Article
YTHDC1 aggravates high glucose-induced retinal vascular endothelial cell injury via m6A modification of CDK6.
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- Biology Direct, 2024, v. 19, n. 1, p. 1, doi. 10.1186/s13062-024-00498-7
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- Article
UCHL3 promotes hepatocellular carcinoma progression by stabilizing EEF1A1 through deubiquitination.
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- Biology Direct, 2024, v. 19, n. 1, p. 1, doi. 10.1186/s13062-024-00495-w
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- Article
Single-cell transcriptomic profiling unveils insights into ovarian fibrosis in obese mice.
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- Biology Direct, 2024, v. 19, n. 1, p. 1, doi. 10.1186/s13062-024-00496-9
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- Article
Genomic characteristics and evolution of Multicentric Esophageal and gastric Cardiac Cancer.
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- Biology Direct, 2024, v. 19, n. 1, p. 1, doi. 10.1186/s13062-024-00493-y
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- Article
Identification of metastasis-related genes for predicting prostate cancer diagnosis, metastasis and immunotherapy drug candidates using machine learning approaches.
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- Biology Direct, 2024, v. 19, n. 1, p. 1, doi. 10.1186/s13062-024-00494-x
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- Article
Silencing LINC00987 ameliorates adriamycin resistance of acute myeloid leukemia via miR-4458/HMGA2 axis.
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- Biology Direct, 2024, v. 19, n. 1, p. 1, doi. 10.1186/s13062-024-00490-1
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- Article
PNSC928, a plant-derived compound, specifically disrupts CtBP2-p300 interaction and reduces inflammation in mice with acute respiratory distress syndrome.
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- Biology Direct, 2024, v. 19, n. 1, p. 1, doi. 10.1186/s13062-024-00491-0
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- Article
C-MYC-activated lncRNA SNHG20 accelerates the proliferation of diffuse large B cell lymphoma via USP14-mediated deubiquitination of β-catenin.
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- Biology Direct, 2024, v. 19, n. 1, p. 1, doi. 10.1186/s13062-024-00488-9
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- Article
The deubiquitinating protein OTUD6B promotes lung adenocarcinoma progression by stabilizing RIPK1.
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- Biology Direct, 2024, v. 19, n. 1, p. 1, doi. 10.1186/s13062-024-00489-8
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- Article
Hypoxia-induced activation of HIF-1alpha/IL-1beta axis in microglia promotes glioma progression via NF-κB-mediated upregulation of heparanase expression.
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- Biology Direct, 2024, v. 19, n. 1, p. 1, doi. 10.1186/s13062-024-00487-w
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- Article
METTL3 promotes the progression of osteosarcoma through the N6-methyladenosine modification of MCAM via IGF2BP1.
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- Biology Direct, 2024, v. 19, n. 1, p. 1, doi. 10.1186/s13062-024-00486-x
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- Article
M2 macrophage-derived exosomes promote angiogenesis and improve cardiac function after myocardial infarction.
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- Biology Direct, 2024, v. 19, n. 1, p. 1, doi. 10.1186/s13062-024-00485-y
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- Article
YY1 mediated DCUN1D5 transcriptional activation promotes triple-negative breast cancer progression by targeting FN1/PI3K/AKT pathway.
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- Biology Direct, 2024, v. 19, n. 1, p. 1, doi. 10.1186/s13062-024-00481-2
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- Article
Lysine-specific methyltransferase Set7/9 in stemness, differentiation, and development.
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- Biology Direct, 2024, v. 19, n. 1, p. 1, doi. 10.1186/s13062-024-00484-z
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- Article
Plant hormones and phenolic acids response to UV-B stress in Rhododendron chrysanthum pall.
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- Biology Direct, 2024, v. 19, n. 1, p. 1, doi. 10.1186/s13062-024-00483-0
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- Article
Human lung cancer-derived mesenchymal stem cells promote tumor growth and immunosuppression.
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- Biology Direct, 2024, v. 19, n. 1, p. 1, doi. 10.1186/s13062-024-00479-w
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- Article
Identification of novel snoRNA-based biomarkers for clear cell renal cell carcinoma from urine-derived extracellular vesicles.
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- Biology Direct, 2024, v. 19, n. 1, p. 1, doi. 10.1186/s13062-024-00467-0
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- Article
Acetylation- and ubiquitination-regulated SFMBT2 acts as a tumor suppressor in clear cell renal cell carcinoma.
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- Biology Direct, 2024, v. 19, n. 1, p. 1, doi. 10.1186/s13062-024-00480-3
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- Article
UBE2N promotes cell viability and glycolysis by promoting Axin1 ubiquitination in prostate cancer cells.
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- Biology Direct, 2024, v. 19, n. 1, p. 1, doi. 10.1186/s13062-024-00469-y
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- Article
LncRNA PCED1B-AS1 mediates miR-3681-3p/MAP2K7 axis to promote metastasis, invasion and EMT in gastric cancer.
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- Biology Direct, 2024, v. 19, n. 1, p. 1, doi. 10.1186/s13062-024-00468-z
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- Article
Single-molecule long-read methylation profiling reveals regional DNA methylation regulated by Elongator Complex Subunit 2 in Arabidopsis roots experiencing spaceflight.
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- Biology Direct, 2024, v. 19, n. 1, p. 1, doi. 10.1186/s13062-024-00476-z
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- Article
NSUN2 relies on ALYREF to regulate Nrf2-mediated oxidative stress and alleviate Dox-induced liver injury.
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- Biology Direct, 2024, v. 19, n. 1, p. 1, doi. 10.1186/s13062-024-00477-y
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- Article
OTUD5 promotes the growth of hepatocellular carcinoma by deubiquitinating and stabilizing SLC38A1.
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- Biology Direct, 2024, v. 19, n. 1, p. 1, doi. 10.1186/s13062-024-00475-0
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- Article
Loss of AMPK activity induces organelle dysfunction and oxidative stress during oocyte aging.
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- Biology Direct, 2024, v. 19, n. 1, p. 1, doi. 10.1186/s13062-024-00471-4
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- Article
Biomimetic peroxidase MOF-Fe promotes bone defect repair by inhibiting TfR2 and activating the BMP2 pathway.
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- Biology Direct, 2024, v. 19, n. 1, p. 1, doi. 10.1186/s13062-024-00473-2
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- Article
ZNF692 promotes osteosarcoma cell proliferation, migration, and invasion through TNK2-mediated activation of the MEK/ERK pathway.
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- Biology Direct, 2024, v. 19, n. 1, p. 1, doi. 10.1186/s13062-024-00472-3
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- Article
Correction: Comprehensive analysis of mitochondria-related genes indicates that PPP2R2B is a novel biomarker and promotes the progression of bladder cancer via Wnt signaling pathway.
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- 2024
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- Correction Notice
Pharmacological inhibition of mTORC1 reduces neural death and damage volume after MCAO by modulating microglial reactivity.
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- Biology Direct, 2024, v. 19, n. 1, p. 1, doi. 10.1186/s13062-024-00470-5
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- Article
Circ_0002669 promotes osteosarcoma tumorigenesis through directly binding to MYCBP and sponging miR-889-3p.
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- Biology Direct, 2024, v. 19, n. 1, p. 1, doi. 10.1186/s13062-024-00466-1
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- Article
LINC00909 up-regulates pluripotency factors and promotes cancer stemness and metastasis in pancreatic ductal adenocarcinoma by targeting SMAD4.
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- Biology Direct, 2024, v. 19, n. 1, p. 1, doi. 10.1186/s13062-024-00463-4
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- Article
Lactobacillus reuteri mitigates hepatic ischemia/reperfusion injury by modulating gut microbiota and metabolism through the Nrf2/HO-1 signaling.
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- Biology Direct, 2024, v. 19, n. 1, p. 1, doi. 10.1186/s13062-024-00462-5
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- Article
Exploring the role of GhN/AINV23: implications for plant growth, development, and drought tolerance.
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- Biology Direct, 2024, v. 19, n. 1, p. 1, doi. 10.1186/s13062-024-00465-2
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- Article
Mammalian enabled protein enhances tamoxifen sensitivity of the hormone receptor-positive breast cancer patients by suppressing the AKT signaling pathway.
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- Biology Direct, 2024, v. 19, n. 1, p. 1, doi. 10.1186/s13062-024-00464-3
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- Article
Dysregulation and antimetastatic function of circLRIG1 modulated by miR-214-3p/LRIG1 axis in bladder carcinoma.
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- Biology Direct, 2024, v. 19, n. 1, p. 1, doi. 10.1186/s13062-023-00446-x
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- Article
PHF5A promotes esophageal squamous cell carcinoma progression via stabilizing VEGFA.
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- Biology Direct, 2024, v. 19, n. 1, p. 1, doi. 10.1186/s13062-023-00440-3
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- Article
Unlocking hepatocellular carcinoma aggression: STAMBPL1-mediated TRAF2 deubiquitination activates WNT/PI3K/NF-kb signaling pathway.
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- Biology Direct, 2024, v. 19, n. 1, p. 1, doi. 10.1186/s13062-024-00460-7
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- Article
Comprehensive analysis of mitochondria-related genes indicates that PPP2R2B is a novel biomarker and promotes the progression of bladder cancer via Wnt signaling pathway.
- Published in:
- Biology Direct, 2024, v. 19, n. 1, p. 1, doi. 10.1186/s13062-024-00461-6
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- Article
RPL35A promotes the progression of cholangiocarcinoma by mediating HSPA8 ubiquitination.
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- Biology Direct, 2024, v. 19, n. 1, p. 1, doi. 10.1186/s13062-024-00453-6
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- Article
Tissue-specific roles of peroxisomes revealed by expression meta-analysis.
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- Biology Direct, 2024, v. 19, n. 1, p. 1, doi. 10.1186/s13062-024-00458-1
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- Article
USP40 promotes hepatocellular carcinoma cell proliferation, migration and stemness by deubiquitinating and stabilizing Claudin1.
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- Biology Direct, 2024, v. 19, n. 1, p. 1, doi. 10.1186/s13062-024-00456-3
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- Article
Mir-338-3p targeting THBS1 attenuates glioma progression by inhibiting the PI3K/Akt pathway.
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- Biology Direct, 2024, v. 19, n. 1, p. 1, doi. 10.1186/s13062-023-00443-0
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- Article
MiR-31-5p regulates the neuroinflammatory response via TRAF6 in neuropathic pain.
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- Biology Direct, 2024, v. 19, n. 1, p. 1, doi. 10.1186/s13062-023-00434-1
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- Article
PICLS with human cells is the first high throughput screening method for identifying novel compounds that extend lifespan.
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- Biology Direct, 2024, v. 19, n. 1, p. 1, doi. 10.1186/s13062-024-00455-4
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- Article
PLAU promotes growth and attenuates cisplatin chemosensitivity in ARID1A-depleted non-small cell lung cancer through interaction with TM4SF1.
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- Biology Direct, 2024, v. 19, n. 1, p. 1, doi. 10.1186/s13062-024-00452-7
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- Article
Vemurafenib induces senescence in acute myeloid leukemia and myelodysplastic syndrome by activating the HIPPO signaling pathway: implications for potential targeted therapy.
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- Biology Direct, 2024, v. 19, n. 1, p. 1, doi. 10.1186/s13062-023-00451-0
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- Article
GPR137 inactivates Hippo signaling to promote gastric cancer cell malignancy.
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- Biology Direct, 2024, v. 19, n. 1, p. 1, doi. 10.1186/s13062-023-00449-8
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- Article
DTX2 promotes glioma development via regulation of HLTF.
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- Biology Direct, 2024, v. 19, n. 1, p. 1, doi. 10.1186/s13062-023-00447-w
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- Article
Risk assessment of transgender people: implementation of a demasculinizing–feminizing rodent model including the evaluation of thyroid homeostasis.
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- Biology Direct, 2024, v. 19, n. 1, p. 1, doi. 10.1186/s13062-023-00450-1
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- Article
The oncogenic role and regulatory mechanism of PGK1 in human non-small cell lung cancer.
- Published in:
- Biology Direct, 2024, v. 19, n. 1, p. 1, doi. 10.1186/s13062-023-00448-9
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- Article