Works in PEDS: Protein Engineering, Design & Selection, 2018, Vol 31, Issue 7/8

Results: 10

Variable heavy–variable light domain and Fab-arm CrossMabs with charged residue exchanges to enforce correct light chain assembly.

Published in:

PEDS: Protein Engineering, Design & Selection, 2018, v. 31, n. 7/8, p. 289, doi. 10.1093/protein/gzy021

By:

Regula, Joerg Thomas;
Imhof-Jung, Sabine;
Mølhøj, Michael;
Benz, Joerg;
Ehler, Andreas;
Bujotzek, Alexander;
Schaefer, Wolfgang;
Klein, Christian

Publication type:

Article

Synthetic 10FN3-based mono- and bivalent inhibitors of MDM2/X function.

Published in:

PEDS: Protein Engineering, Design & Selection, 2018, v. 31, n. 7/8, p. 301, doi. 10.1093/protein/gzy018

By:

Lau, S -Y;
Siau, J W;
Sobota, R M;
Wang, C -I;
Zhong, P;
Lane, D P;
Ghadessy, F J

Publication type:

Article

Roles of the disulfide bond between the variable and the constant domains of rabbit immunoglobulin kappa chains in thermal stability and affinity.

Published in:

PEDS: Protein Engineering, Design & Selection, 2018, v. 31, n. 7/8, p. 243, doi. 10.1093/protein/gzy008

By:

Kawade, Raiji;
Akiba, Hiroki;
Entzminger, Kevin;
Maruyama, Toshiaki;
Okumura, C J;
Tsumoto, Kouhei

Publication type:

Article

Rational optimization of a monoclonal antibody for simultaneous improvements in its solution properties and biological activity.

Published in:

PEDS: Protein Engineering, Design & Selection, 2018, v. 31, n. 7/8, p. 313, doi. 10.1093/protein/gzy020

By:

Kumar, Sandeep;
Roffi, Kirk;
Tomar, Dheeraj S;
Cirelli, David;
Luksha, Nicholas;
Meyer, Danielle;
Mitchell, Jeffrey;
Allen, Martin J;
Li, Li

Publication type:

Article

Lessons learned from merging wet lab experiments with molecular simulation to improve mAb humanization.

Published in:

PEDS: Protein Engineering, Design & Selection, 2018, v. 31, n. 7/8, p. 257, doi. 10.1093/protein/gzy009

By:

Schwaigerlehner, L;
Pechlaner, M;
Mayrhofer, P;
Oostenbrink, C;
Kunert, R

Publication type:

Article

Generation of orthogonal Fab-based trispecific antibody formats.

Published in:

PEDS: Protein Engineering, Design & Selection, 2018, v. 31, n. 7/8, p. 249, doi. 10.1093/protein/gzy007

By:

Wu, Xiufeng;
Yuan, Richard;
Bacica, Michael;
Demarest, Stephen J

Publication type:

Article

Contribution of an unusual CDR2 element of a single domain antibody in ricin toxin binding affinity and neutralizing activity.

Published in:

PEDS: Protein Engineering, Design & Selection, 2018, v. 31, n. 7/8, p. 277, doi. 10.1093/protein/gzy022

By:

Rudolph, Michael J;
Vance, David J;
Kelow, Simon;
Angalakurthi, Siva Krishna;
Nguyen, Sophie;
Davis, Simon A;
Rong, Yinghui;
Middaugh, C Russell;
Weis, David D;
Dunbrack, Roland

Publication type:

Article

Antibody discovery and the arrow of time.

Published in:

PEDS: Protein Engineering, Design & Selection, 2018, v. 31, n. 7/8, p. 231, doi. 10.1093/protein/gzy026

By:

Huston, James S

Publication type:

Article

Analysis of nanobody paratopes reveals greater diversity than classical antibodies.

Published in:

PEDS: Protein Engineering, Design & Selection, 2018, v. 31, n. 7/8, p. 267, doi. 10.1093/protein/gzy017

By:

Mitchell, Laura S;
Colwell, Lucy J

Publication type:

Article

Affinity maturation of an TpoR targeting antibody in full-length IgG form for enhanced agonist activity.

Published in:

PEDS: Protein Engineering, Design & Selection, 2018, v. 31, n. 7/8, p. 233, doi. 10.1093/protein/gzy002

By:

Yang, Zhuo;
Du, Mingjuan;
Wang, Wei;
Xin, Xiu;
Ma, Peixiang;
Zhang, Hongkai;
Lerner, Richard A

Publication type:

Article