Works in Frontiers in Genetics, 2025

Results: 558

Editorial: Screening and discovering novel biological biomarkers by omic-data to revolutionize tumor management.

Published in:

2025

By:

Wang, Binglin;
Jiang, Yinan;
Wu, Peijie;
Medina-Acosta, Enrique;
Yan, Zhongyi

Publication type:

Editorial

Putative epigenetic regulation mechanisms related to production, carcass and beef quality traits in Nelore cattle.

Published in:

Frontiers in Genetics, 2025, p. 1, doi. 10.3389/fgene.2025.1593444

By:

Afonso, Juliana;
Jun Shim, Woo;
Figueiredo Cardoso, Tainã;
Bruscadin, Jennifer Jéssica;
Oliveira de Lima, Andressa;
Jarles da Silva Diniz, Wellison;
Silva-Vignato, Bárbara;
Soares Garcia, Ingrid;
Liang Andre Tan, Wei;
Silva Neubern de Oliveira, Priscila;
Silva Mello Cesar, Aline;
Barreto Mourão, Gerson;
Zerlotini, Adhemar;
Lehmann Coutinho, Luiz;
Rufino Salinas Fortes, Marina;
Correia de Almeida Regitano, Luciana

Publication type:

Article

Inbreeding patterns and genetic diversity under selection in Teha sheep.

Published in:

Frontiers in Genetics, 2025, p. 1, doi. 10.3389/fgene.2025.1576125

By:

Wang, Shunzhe;
Liang, Long;
Ziyayiding, Dilinigeer;
Jiao, Wenjing;
Kasimu, Hailati;
He, Sangang;
Liu, Mingjun

Publication type:

Article

HyenaCircle: a HyenaDNA-based pretrained large language model for long eccDNA prediction.

Published in:

Frontiers in Genetics, 2025, p. 1, doi. 10.3389/fgene.2025.1641162

By:

Li, Fuyu;
Lu, Wenxiang;
Bai, Yunfei

Publication type:

Article

Why too much biomedical research is often undeserving of the public's trust.

Published in:

Frontiers in Genetics, 2025, p. 1, doi. 10.3389/fgene.2025.1587616

By:

Yarborough, Mark

Publication type:

Article

Correction: Genetic landscape of hypertrophic cardiomyopathy in Hong Kong Chinese population.

Published in:

2025

By:

Lee, Derek P. H.;
Cao, Ye;
Zhang, Lilei

Publication type:

Correction Notice

A machine learning framework for predicting cognitive impairment in aging populations using urinary metal and demographic data.

Published in:

Frontiers in Genetics, 2025, p. 1, doi. 10.3389/fgene.2025.1631228

By:

Ren, Fengchun;
Zhao, Xiao;
Yang, Qin;
Liao, Huaqiang;
Zhang, Yudong;
Liu, Xuemei

Publication type:

Article

Application of chromosome microarray analysis and karyotyping in fetal cardiac abnormalities.

Published in:

Frontiers in Genetics, 2025, p. 1, doi. 10.3389/fgene.2025.1611388

By:

Guo, Yun;
Xin, Xiaoqin;
Zhou, Linju;
Huang, Jungao

Publication type:

Article

Association of the interaction between occupational hazard factors and IL-1β gene polymorphism with cognitive function in electrolytic aluminum workers.

Published in:

Frontiers in Genetics, 2025, p. 1, doi. 10.3389/fgene.2025.1591908

By:

Li, Youxing;
Pang, Yaqin;
Chen, Dongshun;
Lu, Feiyu;
Tian, Hongyan;
Qin, Fengni;
Wei, Kuntao;
Ishak, Ahmad Razali Bin;
Mohd Aris, Mohd Shukri Bin;
Qi, Guangzi

Publication type:

Article

Genetic landscape of hypertrophic cardiomyopathy in Hong Kong Chinese population.

Published in:

Frontiers in Genetics, 2025, p. 1, doi. 10.3389/fgene.2025.1583838

By:

Lee, Derek P. H.;
Cao, Ye;
Zhang, Lilei

Publication type:

Article

Analysis of follow-up data in large biobank cohorts: a review of methodology.

Published in:

Frontiers in Genetics, 2025, p. 1, doi. 10.3389/fgene.2025.1534726

By:

Kolde, Anastassia;
Koitmäe, Merli;
Käärik, Meelis;
Möls, Märt;
Fischer, Krista

Publication type:

Article

Shared genetic loci connect cardiovascular disease with blood pressure and lipid traits in East Asian populations.

Published in:

Frontiers in Genetics, 2025, p. 1, doi. 10.3389/fgene.2025.1635378

By:

Zhong, Peng;
Zhang, Chumeng;
Wu, Qinfeng;
Chang, Xiao

Publication type:

Article

An analysis of gene expression profiles through machine learning uncovers the new diagnostic signature for diabetic foot ulcers.

Published in:

Frontiers in Genetics, 2025, p. 1, doi. 10.3389/fgene.2025.1620749

By:

Li, Yingnan;
Xiao, Ning;
Wang, Zhuoqun;
Wang, Wenhai;
Li, Fengjiao;
Wang, Jiren

Publication type:

Article

Case Report: Novel truncating PPM1D variant in a dichorionic diamniotic (DCDA) twin with Jansen-de Vries syndrome. an updated perspective.

Published in:

Frontiers in Genetics, 2025, p. 1, doi. 10.3389/fgene.2025.1601752

By:

Merida De la Torre, Francisco Javier;
Porta Pelayo, Javier;
Ortiz-Martín, Inmaculada

Publication type:

Article

Key genes of vitamin D metabolism and their roles in the risk and prognosis of cancer.

Published in:

Frontiers in Genetics, 2025, p. 1, doi. 10.3389/fgene.2025.1598525

By:

Zheng, Sijie;
Zhu, Lizhu;
Wang, Yufei;
Hua, Yixin;
Ying, Jie;
Chen, Jianxiang

Publication type:

Article

Gene polymorphisms associated with immunosuppressant adverse effects in systemic lupus erythematosus: a narrative review.

Published in:

Frontiers in Genetics, 2025, p. 1, doi. 10.3389/fgene.2025.1594648

By:

Hamdani, Siva;
Hamijoyo, Laniyati;
Amalia, Riezki;
Barliana, Melisa I.

Publication type:

Article

Association of the MUC5B promoter polymorphism with idiopathic pulmonary fibrosis in a lebanese cohort.

Published in:

Frontiers in Genetics, 2025, p. 1, doi. 10.3389/fgene.2025.1544864

By:

Mouawad, Antoine;
Chouery, Eliane;
Chebly, Alain;
Salem, Nabiha;
Corbani, Sandra;
Safieddine, Maissa;
Dabar, Georges

Publication type:

Article

Directional genomic hybridization (dGH™) identifies small inverted duplications in situ.

Published in:

Frontiers in Genetics, 2025, p. 1, doi. 10.3389/fgene.2025.1604822

By:

Liehr, Thomas;
Cross, Erin;
Kankel, Stefanie

Publication type:

Article

CYLD as a key regulator of myocardial infarction-to-heart failure transition revealed by multi-omics integration.

Published in:

Frontiers in Genetics, 2025, p. 1, doi. 10.3389/fgene.2025.1592985

By:

Xu, Jingya;
Dong, Zhonghua;
Li, Zhaodong;
Wang, Xuan

Publication type:

Article

Case Report: Incidental late-onset Pompe disease diagnosis in a man with no clinical and instrumental evidence of neuromuscular dysfunction.

Published in:

Frontiers in Genetics, 2025, p. 1, doi. 10.3389/fgene.2025.1574381

By:

Sciacco, Monica;
Lucchiari, Sabrina;
Bertolasi, Letizia;
Comi, Giacomo Pietro;
Corti, Stefania;
Ronchi, Dario

Publication type:

Article

Shared pathogenesis in polycystic ovaries and rheumatoid arthritis: an analysis of key genes and pathways.

Published in:

Frontiers in Genetics, 2025, p. 1, doi. 10.3389/fgene.2025.1554139

By:

Ji, Yingying;
Xia, Pengcheng;
Wang, Yan;
Liu, Yang;
Wang, Feng;
Sun, Fenggang;
Feng, Qiang;
Ni, Qingbin;
Li, Yi

Publication type:

Article

Insights into the evolution and regulation of miRNAs from the view of their DNA replication temporal domains.

Published in:

Frontiers in Genetics, 2025, p. 1, doi. 10.3389/fgene.2025.1544802

By:

Wu, Xudong;
Liu, Tingting

Publication type:

Article

Uncovering genetic contributors to developmental delay and intellectual disability: a focus on CNVs in pediatric patients.

Published in:

Frontiers in Genetics, 2025, p. 1, doi. 10.3389/fgene.2025.1539902

By:

Tao, Yilun;
Guo, Hongzhi;
Han, Dong;
Yang, Miao;
Lun, Ting;
Wang, Lihong;
Song, Wenxia;
Wang, Haiwei;
Li, Xiaoze

Publication type:

Article

Identification of neutrophil extracellular trap-related biomarkers in ulcerative colitis based on bioinformatics and machine learning.

Published in:

Frontiers in Genetics, 2025, p. 1, doi. 10.3389/fgene.2025.1589999

By:

Li, Jiao;
Liu, Yupei;
Sun, Zhiyi;
Zeng, Suqi;
Zheng, Caisong

Publication type:

Article

Generalized information criteria for personalized gene network inference.

Published in:

Frontiers in Genetics, 2025, p. 1, doi. 10.3389/fgene.2025.1583756

By:

Park, Heewon;
Imoto, Seiya;
Konishi, Sadanori

Publication type:

Article

Diagnostic yield of 1000 trio analyses with exome and genome sequencing in a clinical setting.

Published in:

Frontiers in Genetics, 2025, p. 1, doi. 10.3389/fgene.2025.1580879

By:

Malmgren, Helena;
Kvarnung, Malin;
Gustafsson, Peter;
Anderlid, Britt-Marie;
Arthur, Cecilia;
Carlsten, Jonas;
De Geer, Karl;
Ehn, Emma;
Grigelioniené, Giedre;
Hammarsjö, Anna;
Helgadottir, Hafdis T.;
Hellström-Pigg, Maritta;
Iwarsson, Erik;
Kuchinskaya, Ekaterina;
Lindelöf, Hillevi;
Mannila, Maria;
Nilsson, Daniel;
Pettersson, Maria;
Rudd, Eva;
Sahlin, Ellika

Publication type:

Article

Integrative bioinformatics analysis of pyroptosis-related genes and immune infiltration patterns in childhood asthma.

Published in:

Frontiers in Genetics, 2025, p. 1, doi. 10.3389/fgene.2025.1557709

By:

Lian, Di;
Lin, Chenye;
Xie, Meiling;
Wei, JianXing;
Huang, Xueling;
Lian, Ke;
Tang, Qiuyu

Publication type:

Article

GTMALoc: prediction of miRNA subcellular localization based on graph transformer and multi-head attention mechanism.

Published in:

Frontiers in Genetics, 2025, p. 1, doi. 10.3389/fgene.2025.1623008

By:

Huang, Xindi;
Jiang, Jipu;
Shi, Lifen;
Yan, Cheng

Publication type:

Article

Two novel variants in CNNM2 disrupts magnesium efflux leading to neurodevelopmental disorders.

Published in:

Frontiers in Genetics, 2025, p. 1, doi. 10.3389/fgene.2025.1600877

By:

Li, Huijuan;
Liu, Jing;
Liu, Yingdi;
Liu, Yaning;
Lu, Kehui;
Wen, Juan;
Zhu, Huimin;
Liang, Desheng;
Li, Zhuo;
Wu, Lingqian

Publication type:

Article

Identification of biomarkers associated with mitochondrial dysfunction and programmed cell death in chronic obstructive pulmonary disease via transcriptomics.

Published in:

Frontiers in Genetics, 2025, p. 1, doi. 10.3389/fgene.2025.1567173

By:

Yang, Xiaojuan;
Duan, Yutao;
Qiu, Lei;
Huang, Xia;
Li, Fei

Publication type:

Article

A xyloglucan endotransglucosylase/hydrolase gene, IbXTH16 , increases cold tolerance in transgenic sweetpotato.

Published in:

Frontiers in Genetics, 2025, p. 1, doi. 10.3389/fgene.2025.1629260

By:

Yu, Tao;
Pan, Jiaquan;
Liu, Sitong;
Yang, Zitong;
Liu, Zhenlei

Publication type:

Article

Benchmarking of feed-forward neural network models for genomic prediction of quantitative traits in pigs.

Published in:

Frontiers in Genetics, 2025, p. 1, doi. 10.3389/fgene.2025.1618891

By:

Wang, Junjian;
Tiezzi, Francesco;
Huang, Yijian;
Maltecca, Christian;
Jiang, Jicai

Publication type:

Article

Clinical characteristics and genetic mutation analysis in 18 pediatric patients with Shwachman-Diamond syndrome.

Published in:

Frontiers in Genetics, 2025, p. 1, doi. 10.3389/fgene.2025.1603782

By:

Wei, Ruoying;
Zhang, Kaihui;
Liu, Chen;
Wei, Xuxia;
Jiang, Qin;
Li, Ji-an;
Huo, Meiling;
Liu, Yinggang;
Abdalla, Mohnad;
Du, Li-an;
Yang, Xiaomei;
Li, Fu

Publication type:

Article

Role of inflammation-related genes as prognostic biomarkers and mechanistic implications in idiopathic pulmonary fibrosis.

Published in:

Frontiers in Genetics, 2025, p. 1, doi. 10.3389/fgene.2025.1602588

By:

Bai, Bing;
Zhao, Wenfei;
Li, Fazhan;
Mi, Yang;
Zheng, Pengyuan

Publication type:

Article

Integrative bioinformatics analysis and experimental validation reveals key genes and regulatory mechanisms in the development of gout.

Published in:

Frontiers in Genetics, 2025, p. 1, doi. 10.3389/fgene.2025.1598835

By:

Yuan, Ye;
Gao, Zhiqiang;
Chen, Jianhong;
Liu, Yuejing;
Zhou, Jingguo

Publication type:

Article

Case Report: A first case of desmin-related myofibrillar myopathy due to inheritance from a confirmed mosaic asymptomatic carrier.

Published in:

Frontiers in Genetics, 2025, p. 1, doi. 10.3389/fgene.2025.1597851

By:

Vlaeminck, Jelle;
Uyttebroeck, Sophie;
De Schutter, Elke;
Cordenier, Ann;
Wellekens, Shauni;
Ströker, Erwin;
De Rooms, Kelly;
Helsen, Christine;
Hes, Frederik J.;
Giron, Philippe

Publication type:

Article

Regulation of term and preterm labor: genetics and epigenetics.

Published in:

Frontiers in Genetics, 2025, p. 1, doi. 10.3389/fgene.2025.1594030

By:

Sun, Kaiyi;
Wang, Ning;
Liu, Yuanyuan;
Gao, Lu

Publication type:

Article

Whole genome sequencing and functional annotation of Fusarium oxysporum f. sp. lentis to unravel virulence and secondary metabolite biosynthesis gene clusters.

Published in:

Frontiers in Genetics, 2025, p. 1, doi. 10.3389/fgene.2025.1585510

By:

Kharte, Sanjay;
Kumar, Ashish;
Mishra, Priyamvada;
Ramakrishnan, R. S.;
Sharma, Stuti;
Mishra, Nishi;
Chauhan, Puneet Singh;
Sharma, Radheshyam;
Gautam, Vedant;
Tiwari, Shweta;
Goyal, Vinod;
Sharma, Sonu;
Koutu, G. K.;
Joshi, N. K.

Publication type:

Article

Identification of three T cell-related genes as diagnostic and prognostic biomarkers for triple-negative breast cancer and exploration of potential mechanisms.

Published in:

Frontiers in Genetics, 2025, p. 1, doi. 10.3389/fgene.2025.1584334

By:

He, Zhi-Chuan;
Song, Zheng-Zheng;
Wu, Zhe;
Lin, Peng-Fei;
Wang, Xin-Xing

Publication type:

Article

Novel causative RYR2 indel variant with exon and intron involvement inducing exon 13 skipping in a family exhibiting catecholaminergic polymorphic ventricular tachycardia.

Published in:

Frontiers in Genetics, 2025, p. 1, doi. 10.3389/fgene.2025.1581535

By:

Shin, Ju Hyeon;
Park, Taek Kyu;
Chang, Sung-A.;
Jang, Shin Yi;
Huh, June;
Seol, Chang Ahn;
Park, Kyoung-Jin;
Kim, Sung Hoon;
Kim, Duk-Kyung;
Gwag, Hye Bin;
Jang, Mi-Ae

Publication type:

Article

Case Report: A case of ALS type 6 associated with a FUS gene variant and right limb muscle weakness and atrophy as the initial symptom.

Published in:

Frontiers in Genetics, 2025, p. 1, doi. 10.3389/fgene.2025.1578249

By:

Zhan, Xiuping;
Xuan, Tingting;
Chen, Xiaoyan;
He, Jianhang;
Ren, Yazhou;
Meng, Yue;
Chen, Guisheng;
Li, Haining

Publication type:

Article

Application of non-invasive prenatal testing for fetal chromosomal disorders in low-risk pregnancies: a follow-up study in central China.

Published in:

Frontiers in Genetics, 2025, p. 1, doi. 10.3389/fgene.2025.1574775

By:

Huang, Qiuxiang;
Xu, Qiao;
Chen, Meihuan;
Fan, Wenli;
Huang, Hailong

Publication type:

Article

Epigenetic mechanisms linking atherosclerosis to ischemic stroke: insights from DNA methylation and transcriptome integration.

Published in:

Frontiers in Genetics, 2025, p. 1, doi. 10.3389/fgene.2025.1567951

By:

Ding, Binrong;
Wang, Yiqun;
Li, Junfeng;
Zhang, Xuewei;
Wan, Zhengqing;
Wang, Hao

Publication type:

Article

Data simulation to optimize frameworks for genome-wide association studies in diverse populations.

Published in:

Frontiers in Genetics, 2025, p. 1, doi. 10.3389/fgene.2025.1559496

By:

Mugo, Jacquiline W.;
Mulder, Nicola;
Chimusa, Emile R.

Publication type:

Article

Epigenetic study of the long-term effects of gulf War illness.

Published in:

Frontiers in Genetics, 2025, p. 1, doi. 10.3389/fgene.2025.1553410

By:

Jones, B. C.;
O'Callaghan, J. P.;
Ashbrook, D. G.;
Lu, L.;
Prins, P.;
Zhao, W.;
Mozhui, K.

Publication type:

Article

Identification and functional characterization of ABCA4 gene variants in three patients with Stargardt disease or retinitis pigmentosa.

Published in:

Frontiers in Genetics, 2025, p. 1, doi. 10.3389/fgene.2025.1516872

By:

Luo, Qi;
Huang, Juan;
Shi, Lu;
Zhang, Guanghong;
Xue, Linping;
Wu, Kehu;
Li, Xiaoyu;
Yang, Lei;
Li, Dujun;
Mao, Liangwei;
Luo, Jihong

Publication type:

Article

Transcriptomic analysis and machine learning modeling identifies novel biomarkers and genetic characteristics of hypertrophic cardiomyopathy.

Published in:

Frontiers in Genetics, 2025, p. 1, doi. 10.3389/fgene.2025.1596049

By:

Zhang, Feng;
Li, Chunrui;
Zhang, Lulu

Publication type:

Article

Case Report: Successful late-line pralsetinib treatment in an ALK-rearranged lung adenocarcinoma patient with KIF5B-RET fusion resistant to alectinib.

Published in:

Frontiers in Genetics, 2025, p. 1, doi. 10.3389/fgene.2025.1569912

By:

Jin, Feng;
Wang, Chenyang;
Yang, Fang;
Wang, Shubin;
Wang, Fen

Publication type:

Article

Reduced T-Cell stemness underlies Th17 expansion and graft dysfunction in kidney transplant recipients.

Published in:

Frontiers in Genetics, 2025, p. 1, doi. 10.3389/fgene.2025.1588941

By:

Liu, Chang;
Jiang, Hao;
Zhu, Andu;
Xu, Chen;
Wang, Zhenfan;
Mao, Guocai;
Jiang, Minjun;
Chen, Jianchun;
Ma, Zheng;
Qi, Jiaqian;
Cao, Zhijun

Publication type:

Article

The joint role of the immune microenvironment and N<sup>7</sup>-methylguanosine for prognosis prediction and targeted therapy in acute myeloid leukemia.

Published in:

Frontiers in Genetics, 2025, p. 1, doi. 10.3389/fgene.2025.1540992

By:

Chen, Zhixiang;
Chen, Zhimei;
Huang, Xiaobo;
Yan, Xiongbin;
Lai, Xiaolin;
Wang, Shaoyuan

Publication type:

Article