Works in Frontiers in Pharmacology, 2014, Vol 5

Results: 236

Inflammatory and immune responses in the cochlea: potential therapeutic targets for sensorineural hearing loss.

Published in:

Frontiers in Pharmacology, 2014, v. 5, p. 1, doi. 10.3389/fphar.2014.00287

By:

Masato Fujioka;
Hideyuki Okano;
Kaoru Ogawa;
Tetsuo Morihana;
Takamasa Yoshida

Publication type:

Article

Is redox signaling a feasible target for overcoming multidrug resistance in cancer chemotherapy?

Published in:

2014

By:

Polimeni, Manuela;
Gazzano, Elena;
Kopecka, Joanna;
Bergandi, Lordana;
Niso, Mauro

Publication type:

Opinion

Combating and overcoming drug resistance in cancer.

Published in:

2014

By:

Price, Douglas K.;
Rodríguez-Serrano, Fernando

Publication type:

Book Review

Retraction: Baicalin induced dendritic cell apoptosis in vitro.

Published in:: Frontiers in Pharmacology, 2014, v. 5, p. 1, doi. 10.3389/fphar.2014.00283
Publication type:: Article

Deleterious effects of maternal ingestion of cocoa upon fetal ductus arteriosus in late pregnancy.

Published in:

Frontiers in Pharmacology, 2014, v. 5, p. 1, doi. 10.3389/fphar.2014.00281

By:

Zielinsky, Paulo;
Martignoni, Felipe V.;
Vian, Izabele;
Trabace, Luigia;
Hye Khan, Md. Abdul

Publication type:

Article

Opioid receptor desensitization: mechanisms and its link to tolerance.

Published in:

Frontiers in Pharmacology, 2014, v. 5, p. 1, doi. 10.3389/fphar.2014.00280

By:

Allouche, Stéphane;
Noble, Florence;
Marie, Nicolas;
Bailey, Chris;
Mollereau, Catherine

Publication type:

Article

Role of NG2 expressing cells in addiction: a new approach for an old problem.

Published in:

Frontiers in Pharmacology, 2014, v. 5, p. 1, doi. 10.3389/fphar.2014.00279

By:

Somkuwar, Sucharita S.;
Staples, Miranda C.;
Galinato, Melissa H.;
Fannon, McKenzie J.;
Mandyam, Chitra D.;
Sanna, Enrico;
Kippin, Tod Edward

Publication type:

Article

The effect of deficient muscarinic signaling on commonly reported biochemical effects in schizophrenia and convergence with genetic susceptibility loci in explaining symptom dimensions of psychosis.

Published in:

Frontiers in Pharmacology, 2014, v. 5, p. 1, doi. 10.3389/fphar.2014.00277

By:

Vakalopoulos, Costa;
Tattersall, David;
Sheardown, Malcolm James

Publication type:

Article

Hemophilia A: an ideal disease to correct in utero.

Published in:

Frontiers in Pharmacology, 2014, v. 5, p. 1, doi. 10.3389/fphar.2014.00276

By:

Porada, Christopher D.;
Rodman, Christopher;
Ignacio, Glicerio;
Atala, Anthony;
Almeida-Porada, Graça;
Gros, Robert;
Derderian, Sarkis

Publication type:

Article

Antimicrobial peptides: a new class of antimalarial drugs?

Published in:

Frontiers in Pharmacology, 2014, v. 5, p. 1, doi. 10.3389/fphar.2014.00275

By:

Vale, Nuno;
Aguiar, Luísa;
Gomes, Paula;
Franco, Octavio Luiz;
Rivas, Luis

Publication type:

Article

Use of systems pharmacology modeling to elucidate the operating characteristics of SGLT1 and SGLT2 in renal glucose reabsorption in humans.

Published in:

Frontiers in Pharmacology, 2014, v. 5, p. 1, doi. 10.3389/fphar.2014.00274

By:

Yasong Lu;
Griffen, Steven C.;
Boulton, David W.;
Leil, Tarek A.;
Vallon, Volker;
Sabino-Silva, Robinson

Publication type:

Article

Glutathione depletion in survival and apoptotic pathways.

Published in:

2014

By:

De Nicola, Milena;
Ghibelli, Lina;
Ahmad, Muzamil

Publication type:

Opinion

Alterations in function and expression of ABC transporters at blood-brain barrier under diabetes and the clinical significances.

Published in:

Frontiers in Pharmacology, 2014, v. 5, p. 1, doi. 10.3389/fphar.2014.00273

By:

Li Liu;
Xiao-Dong Liu;
Maggi, Adriana;
Caraci, Filippo

Publication type:

Article

Rikkunshito, a ghrelin potentiator, ameliorates anorexia-cachexia syndrome.

Published in:

Frontiers in Pharmacology, 2014, v. 5, p. 1, doi. 10.3389/fphar.2014.00271

By:

Naoki Fujitsuka;
Yasuhito Uezono;
Ikuroh Ohsawa;
Xiao-Qing Tang

Publication type:

Article

In utero therapy for congenital disorders using amniotic fluid stem cells.

Published in:

Frontiers in Pharmacology, 2014, v. 5, p. 1, doi. 10.3389/fphar.2014.00270

By:

Ramachandra, Durrgah L.;
Shaw, Steven S. W.;
Shangaris, Panicos;
Loukogeorgakis, Stavros;
Guillot, Pascale V.;
De Coppi, Paolo;
David, Anna L.;
Porada, Christopher D.;
Götherström, Cecilia

Publication type:

Article

Strategy for communicating benefit-risk decisions: a comparison of regulatory agencies' publicly available documents.

Published in:

Frontiers in Pharmacology, 2014, v. 5, p. 1, doi. 10.3389/fphar.2014.00269

By:

Wai Yeen, James Leong;
Salek, Sam;
Walker, Stuart;
Criscuolo, Domenico;
Dubois, Dominique J.

Publication type:

Article

Antibodies to probe endogenous G protein-coupled receptor heteromer expression, regulation, and function.

Published in:

Frontiers in Pharmacology, 2014, v. 5, p. 1, doi. 10.3389/fphar.2014.00268

By:

Gomes, Ivone;
Gupta, Achla;
Bushlin, Ittai;
Devi, Lakshmi A.;
Meneses, Alfredo;
Ferre, Sergi

Publication type:

Article

Pharmacoeconomic studies in Nepal: the need of the hour.

Published in:

2014

By:

Acharya, Mahip;
Garcia Tsuji, Rosana Lima;
De Groot, Folkert;
Shaikh, Javed S.

Publication type:

Opinion

Natural antioxidants for health promotion and disease prevention.

Published in:

2014

By:

Xing Zhang;
Feng Gao;
Dirsch, Verena M.

Publication type:

Book Review

Interleukin-12 family cytokines and sarcoidosis.

Published in:

Frontiers in Pharmacology, 2014, v. 5, p. 1, doi. 10.3389/fphar.2014.00233

By:

Ringkowski, Sabine;
Thomas, Paul S.;
Herbert, Cristan;
Fukumoto, Jutaro;
Manali, Effrosyni D.

Publication type:

Article

Virtual Systems Pharmacology (ViSP) software for simulation from mechanistic systems-level models.

Published in:

Frontiers in Pharmacology, 2014, v. 5, p. 1, doi. 10.3389/fphar.2014.00232

By:

Ermakov, Sergey;
Forster, Peter;
Pagidala, Jyotsna;
Miladinov, Marko;
Wang, Albert;
Baillie, Rebecca;
Bartlett, Derek;
Reed, Mike;
Leil, Tarek A.;
Benfenati, Emilio;
Leggio, Gian Marco

Publication type:

Article

Toll-like receptors in systemic lupus erythematosus: potential for personalized treatment.

Published in:

Frontiers in Pharmacology, 2014, v. 5, p. 1, doi. 10.3389/fphar.2014.00265

By:

Celhar, Teja;
Fairhurst, Anna-Marie;
Reichardt, Juergen;
Pavlovic, Sonja

Publication type:

Article

Application of insulin-like growth factor-1 in the treatment of inner ear disorders.

Published in:

Frontiers in Pharmacology, 2014, v. 5, p. 1, doi. 10.3389/fphar.2014.00208

By:

Yamamoto, Norio;
Nakagawa, Takayuki;
Ito, Juichi

Publication type:

Article

Phenotypic screening in the 21st century.

Published in:

2014

By:

Priest, Birgit T.;
Erdemli, Gul;
Salomone, Salvatore

Publication type:

Editorial

The inducible caspase-9 suicide gene system as a "safety switch" to limit on-target, off-tumor toxicities of chimeric antigen receptor T cells.

Published in:

Frontiers in Pharmacology, 2014, v. 5, p. 1, doi. 10.3389/fphar.2014.00235

By:

Gargett, Tessa;
Brown, Michael P.;
Cavone, Leonardo;
Fehse, Boris

Publication type:

Article

Editorial: New therapeutic targets for human placental angiogenesis disease.

Published in:

2014

By:

Escudero, Carlos A.;
Ojeda, Norma Beatriz

Publication type:

Editorial

Evolving toward a human-cell based and multiscale approach to drug discovery for CNS disorders.

Published in:

Frontiers in Pharmacology, 2014, v. 5, p. 1, doi. 10.3389/fphar.2014.00252

By:

Schadt, Eric E.;
Buchanan, Sean;
Brennand, Kristen J.;
Merchant, Kalpana M.;
Auld, Douglas;
Solomon, Jonathan M.

Publication type:

Article

Biological redundancy of endogenous GPCR ligands in the gut and the potential for endogenous functional selectivity.

Published in:

Frontiers in Pharmacology, 2014, v. 5, p. 1, doi. 10.3389/fphar.2014.00262

By:

Thompson, Georgina L.;
Canals, Meritxell;
Poole, Daniel P.;
Fichna, Jakub;
Hornby, Pamela J.

Publication type:

Article

Pharmacokinetic non-interaction analysis in a fixed-dose formulation in combination of atorvastatin and ezetimibe.

Published in:

Frontiers in Pharmacology, 2014, v. 5, p. 1, doi. 10.3389/fphar.2014.00261

By:

Patiño-Rodríguez, Omar;
Torres-Roque, Irma;
Martínez-Delgado, Maricela;
Escobedo-Moratilla, Abraham;
Pérez-Urizar, José;
Lohman, Rink-Jan;
Leggio, Gian Marco

Publication type:

Article

Glutathione revisited: a better scavenger than previously thought.

Published in:

Frontiers in Pharmacology, 2014, v. 5, p. 1, doi. 10.3389/fphar.2014.00260

By:

Haenen, Guido R. M. M.;
Bast, Aalt;
Salomone, Salvatore;
Rezk, Bashir M.

Publication type:

Article

Structural plasticity in mesencephalic dopaminergic neurons produced by drugs of abuse: critical role of BDNF and dopamine.

Published in:

Frontiers in Pharmacology, 2014, v. 5, p. 1, doi. 10.3389/fphar.2014.00259

By:

Collo, Ginetta;
Cavalleri, Laura;
Spano, PierFranco;
Yan Dong;
Melis, Miriam

Publication type:

Article

Applications of linking PBPK and PD models to predict the impact of genotypic variability, formulation differences, differences in target binding capacity and target site drug concentrations on drug responses and variability.

Published in:

Frontiers in Pharmacology, 2014, v. 5, p. 1, doi. 10.3389/fphar.2014.00258

By:

Chetty, Manoranjenni;
Rose, Rachel H.;
Abduljalil, Khaled;
Patel, Nikunjkumar;
Gaohua Lu;
Cain, Theresa;
Jamei, Masoud;
Rostami-Hodjegan, Amin;
Bruno, Valeria;
Hempel, Georg

Publication type:

Article

Interactions of ABCG2 (BCRP) with epidermal growth factor receptor kinase inhibitors developed for molecular imaging.

Published in:

Frontiers in Pharmacology, 2014, v. 5, p. 1, doi. 10.3389/fphar.2014.00257

By:

Qawasmi, Israa;
Shmuel, Miriam;
Eyal, Sara;
Hideaki Hara;
Broccatelli, Fabio

Publication type:

Article

GABA<sub>A</sub> receptor drugs and neuronal plasticity in reward and aversion: focus on the ventral tegmental area.

Published in:

Frontiers in Pharmacology, 2014, v. 5, p. 1, doi. 10.3389/fphar.2014.00256

By:

Vashchinkina, Elena;
Panhelainen, Anne;
Aitta-aho, Teemu;
Korpi, Esa R.;
Sanna, Enrico;
Trantham-Davidson, Heather

Publication type:

Article

Discovery of GPCR ligands for probing signal transduction pathways.

Published in:

Frontiers in Pharmacology, 2014, v. 5, p. 1, doi. 10.3389/fphar.2014.00255

By:

Brogi, Simone;
Tafi, Andrea;
Désaubry, Laurent;
Nebigil, Canan G.;
Pilc, Andrzej;
Granier, Sebastien;
Schmidhammer, Helmut

Publication type:

Article

Does the kappa opioid receptor system contribute to pain aversion?

Published in:

Frontiers in Pharmacology, 2014, v. 5, p. 1, doi. 10.3389/fphar.2014.00253

By:

Cahill, Catherine M.;
Taylor, Anna M. W.;
Cook, Christopher;
Ong, Edmund;
Morón, Jose A.;
Evans, Christopher J.;
Kirby, Lynn G.;
Woolf, Clifford John

Publication type:

Article

In utero hematopoietic cell transplantation: induction of donor specific immune tolerance and postnatal transplants.

Published in:

Frontiers in Pharmacology, 2014, v. 5, p. 1, doi. 10.3389/fphar.2014.00251

By:

Peranteau, William H.;
Almeida-Porada, Graca;
Porada, Christopher D.

Publication type:

Article

Erratum.

Published in:: 2014
Publication type:: Correction Notice

Should I have this on my bookshelf? A review of Cardiac Drugs in Pregnancy.

Published in:

2014

By:

Rieder, Michael J.;
Wagner, Jonathan Burton

Publication type:

Book Review

The role of drug transporters in the kidney: lessons from tenofovir.

Published in:

Frontiers in Pharmacology, 2014, v. 5, p. 1, doi. 10.3389/fphar.2014.00248

By:

Moss, Darren M.;
Neary, Megan;
Owen, Andrew;
Grisk, Olaf;
Argyropoulos, Christos

Publication type:

Article

Quantitative Systems Pharmacology can reduce attrition and improve productivity in pharmaceutical research and development.

Published in:

Frontiers in Pharmacology, 2014, v. 5, p. 1, doi. 10.3389/fphar.2014.00247

By:

Leil, Tarek A.;
Bertz, Richard;
Caraci, Filippo;
McArthur, Robert A.

Publication type:

Article

Analysis of biomarker utility using a PBPK/PD model for carbaryl.

Published in:

Frontiers in Pharmacology, 2014, v. 5, p. 1, doi. 10.3389/fphar.2014.00246

By:

Phillips, Martin B.;
Miyoung Yoon;
Young, Bruce;
Yu-Mei Tan;
Johanson, Gunnar;
Krishnan, Kannan

Publication type:

Article

Emerging role of selective autophagy in human diseases.

Published in:

Frontiers in Pharmacology, 2014, v. 5, p. 1, doi. 10.3389/fphar.2014.00244

By:

Mizumura, Kenji;
Choi, Augustine M. K.;
Ryter, Stefan W.;
Tait, Stephen;
Danhui Liu;
Wagener, Frank

Publication type:

Article

PPAR? signaling is required for mediating EETs protective effects in neonatal cardiomyocytes exposed to LPS.

Published in:

Frontiers in Pharmacology, 2014, v. 5, p. 1, doi. 10.3389/fphar.2014.00242

By:

Samokhvalov, Victor;
Vriend, Jelle;
Jamieson, Kristi L.;
Akhnokh, Maria K.;
Manne, Rajkumar;
Falck, John R.;
Seubert, John M.;
Guabiraba, Rodrigo;
Hye Khan, Md Abdul

Publication type:

Article

Exploring BSEP inhibition-mediated toxicity with a mechanistic model of drug-induced liver injury.

Published in:

Frontiers in Pharmacology, 2014, v. 5, p. 1, doi. 10.3389/fphar.2014.00240

By:

Woodhead, Jeffrey L.;
Kyunghee Yang;
Siler, Scott Q.;
Watkins, Paul B.;
Brouwer, Kim L. R.;
Barton, Hugh A.;
Howel, Brett A.;
Maggi, Adriana;
Lohman, Rink-Jan

Publication type:

Article

Suicide genes: monitoring cells in patients with a safety switch.

Published in:

Frontiers in Pharmacology, 2014, v. 5, p. 1, doi. 10.3389/fphar.2014.00241

By:

Eissenberg, Linda G.;
Rettig, Michael;
Dehdashti, Farrokh;
Piwnica-Worms, David;
DiPersio, John F.;
Caraci, Filippo;
Bondanza, Attilio

Publication type:

Article

Inside epoxyeicosatrienoic acids and cardiovascular disease.

Published in:

Frontiers in Pharmacology, 2014, v. 5, p. 1, doi. 10.3389/fphar.2014.00239

By:

Tacconelli, Stefania;
Patrignani, Paola;
Mizanur, Rahman M.;
Wei Ni

Publication type:

Article

Gene expression and highly diluted molecules.

Published in:

2014

By:

Marzotto, Marta;
Olioso, Debora;
Bellavite, Paolo;
Fang-Rong Chang;
Hwee-Ling Koh;
Green, Benedict

Publication type:

Opinion

Free fatty acid receptors as therapeutic targets for the treatment of diabetes.

Published in:

Frontiers in Pharmacology, 2014, v. 5, p. 1, doi. 10.3389/fphar.2014.00236

By:

Atsuhiko Ichimura;
Sae Hasegawa;
Mayu Kasubuchi;
Ikuo Kimura;
Hudson, Brian;
Cho, Thomas Y.

Publication type:

Article

Understanding transporter specificity and the discrete appearance of channel-like gating domains in transporters.

Published in:

Frontiers in Pharmacology, 2014, v. 5, p. 1, doi. 10.3389/fphar.2014.00207

By:

Diallinas, George

Publication type:

Article