Works in Frontiers in Pharmacology, 2022, Vol 13

Results: 5000

Derinat® has an immunomodulatory and anti-inflammatory effect on the model of acute lung injury in male SD rats.

Published in:

Frontiers in Pharmacology, 2022, v. 13, p. 01, doi. 10.3389/fphar.2022.1111340

By:

Palikova, Yulia A.;
Palikov, Victor A.;
Novikova, Nadezhda I.;
Slashcheva, Gulsara A.;
Rasskazova, Ekaterina A.;
Tukhovskaya, Elena A.;
Danilkovich, Alexey V.;
Dyachenko, Igor A.;
Belogurov Jr., Alexey A.;
Kudriaeva, Anna A.;
Bugrimov, Daniil Y.;
Krasnorutskaya, Olga N.;
Murashev, Arkady N.

Publication type:

Article

Identifying effective diagnostic biomarkers and immune infiltration features in chronic kidney disease by bioinformatics and validation.

Published in:

Frontiers in Pharmacology, 2022, v. 13, p. 01, doi. 10.3389/fphar.2022.1069810

By:

Tao Liu;
Xing Xing Zhuang;
Xiu Juan Qin;
Liang Bing Wei;
Jia Rong Gao

Publication type:

Article

Dispensing of psychotropic drugs in the Brazilian capital city before and during the COVID-19 pandemic (2018-2020).

Published in:

Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.1028233

By:

Escalante Saavedra, Pamela Alejandra;
Galato, Dayani;
Maria de Souza Silva, Calliandra;
Rodrigues da Silva, Izabel Cristina;
Vitoria da Silva, Emília

Publication type:

Article

A case report of severe pirimiphos-methyl intoxication: Clinical findings and cholinesterase status.

Published in:

Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.1102160

By:

Zellner, Tobias;
Rabe, Christian;
von der Wellen-Pawlowski, Jens;
Hansen, Dagmar;
John, Harald;
Worek, Franz;
Eyer, Florian

Publication type:

Article

Treatment for chemotherapy-induced peripheral neuropathy: A systematic review of randomized control trials.

Published in:

Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.1080888

By:

Chenkun Wang;
Si Chen;
Weiwei Jiang

Publication type:

Article

Genetically proxied inhibition of tumor necrosis factor and the risk of colorectal cancer: A drug-target mendelian randomization study.

Published in:

Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.1079953

By:

Min Chen;
Qian Chen;
Xin-Yu Xiao;
Si-Jia Feng;
Xiao-Ying Wang;
Tai-Chun Tang;
Hui Zheng

Publication type:

Article

Assessment of toxicity and anti-plasmodial activities of chloroform fractions of Carapa procera and Alchornea cordifolia in murine models.

Published in:

Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.1077380

By:

Mahama, Ayisha;
Chama, Mary Anti;
Bekoe, Emelia Oppong;
Asare, George Awuku;
Obeng-Kyeremeh, Richard;
Amoah, Daniel;
Agbemelo-Tsomafo, Constance;
Eva Amoah, Linda;
Joe Erskine, Isaac;
Kusi, Kwadwo Asamoah;
Adjei, Samuel

Publication type:

Article

Red ginseng extract improves skeletal muscle energy metabolism and mitochondrial function in chronic fatigue mice.

Published in:

Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.1077249

By:

Haijing Zhang;
Chunhui Zhao;
Jinli Hou;
Ping Su;
Yifei Yang;
Bing Xia;
Xiaoang Zhao;
Rong He;
Lifang Wang;
Chunyu Cao;
Ting Liu;
Jixiang Tian

Publication type:

Article

Ultrasonic optic nerve sheath diameter could improve the prognosis of acute ischemic stroke in the intensive care unit.

Published in:

Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.1077131

By:

Cong Li;
Cui-Cui Wang;
Yan Meng;
Jia-Yu Fan;
Jie Zhang;
Li-Juan Wang

Publication type:

Article

Emodin in cardiovascular disease: The role and therapeutic potential.

Published in:

Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.1070567

By:

Yuanyuan Guo;
Rongzhen Zhang;
Wenlan Li

Publication type:

Article

Wogonin increases gemcitabine sensitivity in pancreatic cancer by inhibiting Akt pathway.

Published in:

Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.1068855

By:

Tianli Zhang;
Mengmeng Liu;
Qing Liu;
Gary Guishan Xiao

Publication type:

Article

Morroniside ameliorates inflammatory skeletal muscle atrophy via inhibiting canonical and non-canonical NF-κB and regulating protein synthesis/ degradation.

Published in:

Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.1056460

By:

Xiangjiao Yi;
Jianguo Tao;
Yu Qian;
Feng Feng;
Xueqin Hu;
Taotao Xu;
Hongting Jin;
Hongfeng Ruan;
Hou-Feng Zheng;
Peijian Tong

Publication type:

Article

Lonicerin attenuates house dust mite-induced eosinophilic asthma through targeting Src/ EGFR signaling.

Published in:

Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.1051344

By:

Zhenan Deng;
Xuefei Zhang;
Junjie Wen;
Xiaojing Yang;
Lingna Xue;
Changxing Ou;
Jianjuan Ma;
Hongrui Zhan;
Xiaomin Cen;
Xuliang Cai;
Yu Zhang;
Riken Chen;
Qingling Zhang

Publication type:

Article

Effect of Pheretima aspergillum on reducing fibrosis: A systematic review and meta-analysis.

Published in:

Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.1039553

By:

Tianren Xu;
Xiaonan Liu;
Shengguang Wang;
Hongwei Kong;
Xiaojun Yu;
Congying Liu;
Huaying Song;
Peng Gao;
Xin Zhang

Publication type:

Article

The effects of qishen granules for patients with chronic heart failure: A multicenter randomized double-blind placebo-controlled trial.

Published in:

Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.1017734

By:

Kangjia Du;
Junjie Liu;
Nannan Tan;
Xinyi Huang;
Juan Wang;
Huihui Zhao;
Wei Wang

Publication type:

Article

Immunotherapy strategies and prospects for acute lung injury: Focus on immune cells and cytokines.

Published in:

Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.1103309

By:

Wenfang Zhu;
Yiwen Zhang;
Yinghong Wang

Publication type:

Article

Discovery of potent and noncovalent KRASG12D inhibitors: Structure-based virtual screening and biological evaluation.

Published in:

Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.1094887

By:

Yuting Wang;
Hai Zhang;
Jindong Li;
Miao-Miao Niu;
Yang Zhou;
Yuanqian Qu

Publication type:

Article

Trilateral association of autophagy, mTOR and Alzheimer's disease: Potential pathway in the development for Alzheimer's disease therapy.

Published in:

Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.1094351

By:

Subramanian, Arunkumar;
Tamilanban, T.;
Alsayari, Abdulrhman;
Ramachawolran, Gobinath;
Ling Shing Wong;
Sekar, Mahendran;
Siew Hua Gan;
Subramaniyan, Vetriselvan;
Chinni, Suresh V.;
Rani, Nur Najihah Izzati Mat;
Suryadevara, Nagaraja;
Wahab, Shadma

Publication type:

Article

A review of recent advances on single use of antibody-drug conjugates or combination with tumor immunology therapy for gynecologic cancer.

Published in:

Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.1093666

By:

An-Jin Wang;
Yang Gao;
Yu-Ying Shi;
Meng-Yuan Dai;
Hong-Bing Cai

Publication type:

Article

Puerariae lobatae radix protects against UVB-induced skin aging via antagonism of REV-ERBα in mice.

Published in:

Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.1088294

By:

Luyao Ma;
Meiping Huang;
Guanghui Sun;
Yanke Lin;
Danyi Lu;
Baojian Wu

Publication type:

Article

Apigenin directly interacts with and inhibits topoisomerase 1 to upregulate CD26/DPP4 on colorectal carcinoma cells.

Published in:

Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.1086894

By:

Fux, Julia E.;
Lefort, Émilie C.;
Rao, Praveen P. N.;
Blay, Jonathan

Publication type:

Article

Methylome-wide association study of different responses to risperidone in schizophrenia.

Published in:

Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.1078464

By:

Huihui Du;
Jingsong Ma;
Wei Zhou;
Mo Li;
Cong Huai;
Lu Shen;
Hao Wu;
Xianglong Zhao;
Na Zhang;
Songyin Gao;
Qi Wang;
Lin He;
Xuming Wu;
Shengying Qin;
Mingzhe Zhao

Publication type:

Article

Corrigendum: SGLT2 inhibitors suppress epithelial-mesenchymal transition in podocytes under diabetic conditions via downregulating the IGF1R/PI3K pathway.

Published in:: Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.1074294
Publication type:: Article

Ursolic acid and rosmarinic acid ameliorate alterations in hippocampal neurogenesis and social memory induced by amyloid beta in mouse model of Alzheimer's disease.

Published in:

Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.1058358

By:

Mirza, Fatima Javed;
Zahid, Saadia

Publication type:

Article

Activation of cancer immunotherapy by nanomedicine.

Published in:

Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.1041073

By:

Lijuan Wang;
Henan Xu;
Lili Weng;
Jin Sun;
Ye Jin;
Chunping Xiao

Publication type:

Article

Bibliometric analysis on exploitation of biogenic gold and silver nanoparticles in breast, ovarian and cervical cancer therapy.

Published in:

Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.1035769

By:

Bhandari, Meena;
Raj, Seema;
Kumar, Ashwani;
Kau, Dilraj Preet

Publication type:

Article

FGF10 ameliorates lipopolysaccharide-induced acute lung injury in mice via the BMP4-autophagy pathway.

Published in:

Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.1019755

By:

Xiaoxia Kong;
Liling Lu;
Daopeng Lin;
Lei Chong;
Shunhang Wen;
Yaokai Shi;
Lidan Lin;
Liqin Zhou;
Hongyu Zhang;
Hailin Zhang

Publication type:

Article

Drug repositioning based on heterogeneous networks and variational graph autoencoders.

Published in:

Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.1056605

By:

Song Lei;
Xiujuan Lei;
Lian Liu

Publication type:

Article

Reversal of spatial memory impairment by phosphodiesterase 3 inhibitor cilostazol is associated with reduced neuroinflammation and increased cerebral glucose uptake in aged male mice.

Published in:

Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.1031637

By:

Shuichi Yanai;
Tetsuro Tago;
Jun Toyohara;
Tomoko Arasaki;
Shogo Endo

Publication type:

Article

Efficacy and safety of ciprofol-remifentanil versus propofol-remifentanil during fiberoptic bronchoscopy: A prospective, randomized, double-blind, non-inferiority trial.

Published in:

Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.1091579

By:

Bin Wu;
Wenchao Zhu;
Qinghe Wang;
Chunguang Ren;
Lizhen Wang;
Guannan Xie

Publication type:

Article

Role of bioactive compounds in the treatment of hepatitis: A review.

Published in:

Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.1051751

By:

Roy, Arpita;
Roy, Madhura;
Gacem, Amel;
Datta, Shreeja;
Zeyaullah, Md.;
Muzammil, Khursheed;
Farghaly, Thoraya A.;
Abdellattif, Magda H.;
Yadav, Krishna Kumar;
Simal-Gandara, Jesus

Publication type:

Article

Effects of the Radix Ginseng and Semen Ziziphi Spinosae drug pair on the GLU/GABA-GLN metabolic cycle and the intestinal microflora of insomniac rats based on the brain–gut axis.

Published in:

Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.1094507

By:

Tie Qiao;
Yuan Wang;
Ke Liang;
Bingyuan Zheng;
Jin Ma;
Fangxiao Li;
Chi Liu;
Mingdan Zhu;
Meng Song

Publication type:

Article

The role of Phosphodiesterase-1 and its natural product inhibitors in Alzheimer’s disease: A review.

Published in:

Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.1070677

By:

Ahmad, Nazir;
Lesa, Kaisun Nesa;
Sudarmanto, Ari;
Fakhrudin, Nanang;
Ikawati, Zullies

Publication type:

Article

Exploring the effects of drug, disease, and protein dependencies on biomedical named entity recognition: A comparative analysis.

Published in:

Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.1020759

By:

Peifu Han;
Xue Li;
Xun Wang;
Shuang Wang;
Changnan Gao;
Wenqi Chen

Publication type:

Article

Cyclovirobuxine D, a cardiovascular drug from traditional Chinese medicine, alleviates inflammatory and neuropathic pain mainly via inhibition of voltage-gated Cav3.2 channels

Published in:

Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.1081697

By:

Deyuan Su;
Ye Gong;
Songyu Li;
Jian Yang;
Yin Nian

Publication type:

Article

Triplex-forming oligonucleotides as an anti-gene technique for cancer therapy.

Published in:

Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.1007723

By:

Chun Li;
Zunzhen Zhou;
Chao Ren;
Yi Deng;
Feng Peng;
Qiongfen Wang;
Hong Zhang;
Yuan Jiang

Publication type:

Article

Cuproptosis-related lncRNA signatures predict prognosis and immune relevance of kidney renal papillary cell carcinoma.

Published in:

Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.1103986

By:

Tongjin Xie;
Bin Liu;
Dongbo Liu;
Yusong Zhou;
Qingping Yang;
Dai Wang;
Mengjie Tang;
Wei Liu

Publication type:

Article

Myriocin enhances the antifungal activity of fluconazole by blocking the membrane localization of the efflux pump Cdr1.

Published in:

Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.1101553

By:

Hongkang Wang;
Zhe Ji;
Yanru Feng;
Tianhua Yan;
Yongbing Cao;
Hui Lu;
Yuanying Jiang

Publication type:

Article

A KCNB1 gain of function variant causes developmental delay and speech apraxia but not seizures.

Published in:

Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.1093313

By:

Veale, Emma L.;
Golluscio, Alessia;
Grand, Katheryn;
Graham Jr., John M.;
Mathie, Alistair

Publication type:

Article

The potential function and clinical application of FGF21 in metabolic diseases.

Published in:

Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.1089214

By:

Zhiwei Chen;
Lili Yang;
Yang Liu;
Ping Huang;
Haiyan Song;
Peiyong Zheng

Publication type:

Article

Clinical efficacy of azacytidine and venetoclax and prognostic impact of Tim-3 and galectin-9 in acute myeloid leukemia and high-risk myelodysplastic syndromes: A single-center real-life experience.

Published in:

Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.1052060

By:

Giudice, Valentina;
Serio, Bianca;
Ferrara, Idalucia;
Manzo, Paola;
Gorrese, Marisa;
Pepe, Rita;
Bertolini, Angela;
D’Alto, Francesca;
Verdesca, Francesco;
Langella, Maddalena;
Filippelli, Amelia;
Selleri, Carmine

Publication type:

Article

Liver-related long-term outcomes of alpha-glucosidase inhibitors in patients with diabetes and liver cirrhosis.

Published in:

Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.1049094

By:

Fu-Shun Yen;
Ming-Chih Hou;
James Cheng-Chung Wei;
Ying-Hsiu Shih;
Hsu, Chung Y.;
Chih-Cheng Hsu;
Chii-Min Hwu

Publication type:

Article

Commentary: Tailored therapy for Helicobacter pylori eradication: A systematic review and meta-analysis.

Published in:

Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.1090776

By:

Toshihiko Kakiuchi;
Masato Yoshiura

Publication type:

Article

Diversity, distribution, and sustainability of traditional medicinal plants in Kaski district, western Nepal.

Published in:

Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.1076351

By:

Khakurel, Dhruba;
Uprety, Yadav;
Ahn, Gyeongik;
Joon-Yung Cha;
Woe-Yeon Kim;
Sung-Ho Lee;
Rajbhandary, Sangeeta

Publication type:

Article

Combination of the parent analogue of remdesivir (GS-441524) and molnupiravir results in a markedly potent antiviral effect in SARS-CoV-2 infected Syrian hamsters.

Published in:

Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.1072202

By:

Abdelnabi, Rana;
Maes, Piet;
de Jonghe, Steven;
Weynand, Birgit;
Neyts, Johan

Publication type:

Article

Serial five-membered lactone ring ions in the treatment of Alzheimer's diseases-comprehensive profiling of arctigenin metabolites and network analysis.

Published in:

Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.1065654

By:

Yanan Li;
Xianming Lan;
Shaoping Wang;
Yifang Cui;
Shuyi Song;
Hongyan Zhou;
Qiyan Li;
Long Dai;
Jiayu Zhang

Publication type:

Article

Low-dose esketamine for the prevention of emergency agitation in children after tonsillectomy: A randomized controlled study.

Published in:

Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.991581

By:

Qi Li;
Jiaming Fan;
Wangping Zhang

Publication type:

Article

Avocado oil alleviates non-alcoholic fatty liver disease by improving mitochondrial function, oxidative stress and inflammation in rats fed a high fat-High fructose diet.

Published in:

Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.1089130

By:

García-Berumen, Claudia Isabel;
Vargas-Vargas, Manuel Alejandro;
Ortiz-Avila, Omar;
Piña-Zentella, Rosa María;
Ramos-Gómez, Minerva;
Figueroa-García, María del Consuelo;
Mejía-Zepeda, Ricardo;
Rodríguez-Orozco, Alain Raimundo;
Saavedra-Molina, Alfredo;
Cortés-Rojo, Christian

Publication type:

Article

Characterization of lung adenocarcinoma based on immunophenotyping and constructing an immune scoring model to predict prognosis.

Published in:

Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.1081244

By:

Mengfeng Liu;
Qifan Xiao;
Xiran Yu;
Yujie Zhao;
Changfa Qu

Publication type:

Article

Lysophosphatidic acid suppresses apoptosis of high-grade serous ovarian cancer cells by inducing autophagy activity and promotes cell-cycle progression via EGFR-PI3K/Aurora-AThr288-geminin dual signaling pathways.

Published in:

Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.1046269

By:

Haile Zhao;
Peijun Jia;
Nanding, Kathleen;
Man Wu;
Xiaozhou Bai;
Morigen, Morigen;
Lifei Fan

Publication type:

Article