Works in Frontiers in Pharmacology, 2021, Vol 12

Results: 2470

Repurposing Artemisinin and its Derivatives as Anticancer Drugs: A Chance or Challenge?

Published in:

Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.828856

By:

Ma, Zhaowu;
Woon, Clariis Yi-Ning;
Liu, Chen-Guang;
Cheng, Jun-Ting;
You, Mingliang;
Sethi, Gautam;
Wong, Andrea Li-Ann;
Ho, Paul Chi-Lui;
Zhang, Daping;
Ong, Peishi;
Wang, Lingzhi;
Goh, Boon-Cher

Publication type:

Article

Effects and Mechanism of Salvianolic Acid B on the Injury of Human Renal Tubular Epithelial Cells Induced by Iopromide.

Published in:

Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.761908

By:

Dong, Shu-Jun;
Gao, Xin-Yue;
Pei, Ming-Xin;
Luo, Ting;
Fan, Dong;
Chen, Yan-Ling;
Jin, Jun-Feng;
Zhao, Xiao-Duo

Publication type:

Article

A Targeted Approach to Improve Asthma Control Using Community Pharmacists.

Published in:

Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.798263

By:

Serhal, Sarah;
Saini, Bandana;
Bosnic-Anticevich, Sinthia;
Krass, Ines;
Emmerton, Lynne;
Bereznicki, Bonnie;
Bereznicki, Luke;
Mitchell, Bernadette;
Wilson, Frances;
Wright, Bronwen;
Wilson, Kiara;
Weier, Naomi;
Segrott, Rebecca;
Cleveland, Rhonda;
Jan, Stephen;
Shan, Sana;
Billot, Laurent;
Armour, Carol

Publication type:

Article

Inhalation Administration of Agarwood Incense Rescues Scopolamine-Induced Learning and Memory Impairment in Mice.

Published in:

Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.821356

By:

Han, Muxuan;
Zhang, Hao;
Hu, Minghui;
Sun, Wei;
Li, Zifa;
Cao, Guimao;
Geng, Xiwen;
Wei, Sheng

Publication type:

Article

Amelioration of AOM/DSS-Induced Murine Colitis-Associated Cancer by Evodiamine Intervention is Primarily Associated with Gut Microbiota-Metabolism-Inflammatory Signaling Axis.

Published in:

Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.797605

By:

Wang, Mengxia;
Zhou, Biqiang;
Cong, Weihong;
Zhang, Miao;
Li, Ziwen;
Li, Yan;
Liang, Shaoyu;
Chen, Keji;
Yang, Depo;
Wu, Zhengzhi

Publication type:

Article

Potential Benefits of Antiviral African Medicinal Plants in the Management of Viral Infections: Systematic Review.

Published in:

Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.682794

By:

Beressa, Tamirat Bekele;
Deyno, Serawit;
Mtewa, Andrew G.;
Aidah, Namuli;
Tuyiringire, Naasson;
Lukubye, Ben;
Weisheit, Anke;
Tolo, Casim Umba;
Ogwang, Patrick Engeu

Publication type:

Article

RNA Drug Delivery Using Biogenic Nanovehicles for Cancer Therapy.

Published in:

Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.734443

By:

Li, Nuannuan;
Sun, Yiying;
Fu, Yuanlei;
Sun, Kaoxiang

Publication type:

Article

Nanoparticles use for Delivering Ursolic Acid in Cancer Therapy: A Scoping Review.

Published in:

Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.787226

By:

Miatmoko, Andang;
Mianing, Ester Adelia;
Sari, Retno;
Hendradi, Esti

Publication type:

Article

Cost-Effectiveness Analysis of Camrelizumab Plus Chemotherapy vs. Chemotherapy Alone as the First-Line Treatment in Patients With IIIB–IV Non-Squamous Non-Small Cell Lung Cancer (NSCLC) Without EGFR and ALK Alteration from a Perspective of Health - Care System in China

Published in:

Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.735536

By:

Zhu, Chen;
Xing, Xiao-xuan;
Wu, Bin;
Liang, Gang;
Han, Gang;
Lin, Cai-xia;
Fang, Hong-mei

Publication type:

Article

Demonstration of Equivalence of Generic Glatiramer Acetate and Copaxone<sup>®</sup>.

Published in:

Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.760726

By:

Lipsky, Peter;
Vallano, Patrick T.;
Smith, Jeffrey;
Owens, Walter;
Snider, Daniel;
Bandaru, Viswanath;
Sun, Yunfu;
Wallingford, Ross;
Duncan, Joseph;
Lewis, Joshua;
Southall, Jason;
Ansari, Azeem;
Li, Hong

Publication type:

Article

Anlotinib Alone or in Combination With Temozolomide in the Treatment of Recurrent High-Grade Glioma: A Retrospective Analysis.

Published in:

Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.804942

By:

Yang, Qunying;
Guo, Chengcheng;
Lin, Xiaoping;
Luo, Lili;
He, Zhenqiang;
Lin, Fuhua;
Zhang, Ji;
Chen, Yinsheng;
Jiang, Xiaobing;
Ke, Chao;
Mou, Yonggao

Publication type:

Article

New Potential of Roxatidine Acetate Hydrochloride on Atopic Dermatitis Mouse Model, Human Keratinocytes, and Human Skin Equivalent Model.

Published in:

Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.797086

By:

Kang, Yun-Mi;
Lee, Minho;
An, Hyo-Jin

Publication type:

Article

Mechanisms Underlying the Action of Ziziphi Spinosae Semen in the Treatment of Insomnia: A Study Involving Network Pharmacology and Experimental Validation.

Published in:

Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.752211

By:

Bian, Zhenhua;
Zhang, Wenming;
Tang, Jingyue;
Fei, Qianqian;
Hu, Minmin;
Chen, Xiaowei;
Su, Lianlin;
Fei, Chenghao;
Ji, De;
Mao, Chunqin;
Tong, Huangjin;
Yuan, Xiaohang;
Lu, Tulin

Publication type:

Article

Snake Venom Proteomics of Samar Cobra (Naja samarensis) from the Southern Philippines: Short Alpha-Neurotoxins as the Dominant Lethal Component Weakly Cross-Neutralized by the Philippine Cobra Antivenom.

Published in:

Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.727756

By:

Palasuberniam, Praneetha;
Chan, Yi Wei;
Tan, Kae Yi;
Tan, Choo Hock

Publication type:

Article

Deep Eutectic Solvents as Active Pharmaceutical Ingredient Delivery Systems in the Treatment of Metabolic Related Diseases.

Published in:

Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.794939

By:

Huang, Cixin;
Chen, Xiunian;
Wei, Chao;
Wang, Hongwei;
Gao, Hua

Publication type:

Article

Voltage-Gated Sodium Channel Modulation by a New Spider Toxin Ssp1a Isolated From an Australian Theraphosid.

Published in:

Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.795455

By:

Dongol, Yashad;
Choi, Phil M.;
Wilson, David T.;
Daly, Norelle L.;
Cardoso, Fernanda C.;
Lewis, Richard J.

Publication type:

Article

Comparative Cardio-Renal Outcomes of Type 2 Diabetes Patients Administered Glucagon-Like Peptide-1 Receptor Agonists: A Network Meta-Analysis.

Published in:

Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.759262

By:

Zhuo, Chuanjun;
Lin, Chongguang;
Zhou, Chunhua;
Gao, Xiangyang;
Shao, Hailin;
Fang, Tao;
Tian, Hongjun;
Ding, Li;
Liu, Ming

Publication type:

Article

Signaling Potential Therapeutic Herbal Medicine Prescription for Treating COVID-19 by Collaborative Filtering.

Published in:

Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.759479

By:

Yang, Fan;
Zhang, Qi;
Yuan, Zhongshang;
Teng, Saisai;
Cui, Lizhen;
Xue, Fuzhong;
Wei, Leyi

Publication type:

Article

Antioxidant Activity of Fluoxetine and Vortioxetine in a Non-Transgenic Animal Model of Alzheimer's Disease.

Published in:

Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.809541

By:

Caruso, Giuseppe;
Grasso, Margherita;
Fidilio, Annamaria;
Torrisi, Sebastiano Alfio;
Musso, Nicolò;
Geraci, Federica;
Tropea, Maria Rosaria;
Privitera, Anna;
Tascedda, Fabio;
Puzzo, Daniela;
Salomone, Salvatore;
Drago, Filippo;
Leggio, Gian Marco;
Caraci, Filippo

Publication type:

Article

Translational Pharmacokinetic–Pharmacodynamic Modeling of NaV1.7 Inhibitor MK-2075 to Inform Human Efficacious Dose.

Published in:

Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.786078

By:

Ballard, Jeanine E.;
Pall, Parul S.;
Vardigan, Joshua;
Zhao, Fuqiang;
Holahan, Marie A.;
Zhou, Xiaoping;
Jochnowitz, Nina;
Kraus, Richard L.;
Klein, Rebecca M.;
Henze, Darrell A.;
Houghton, Andrea K.;
Burgey, Christopher S.;
Gibson, Christopher;
Struyk, Arie

Publication type:

Article

Latent Transforming Growth Factor-β Binding Protein-2 Regulates Lung Fibroblast-to-Myofibroblast Differentiation in Pulmonary Fibrosis via NF-κB Signaling.

Published in:

Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.788714

By:

Zou, Menglin;
Zou, Jingfeng;
Hu, Xingxing;
Zheng, Weishuai;
Zhang, Mingyang;
Cheng, Zhenshun

Publication type:

Article

SMAD3 Host and Tumor Profiling to Identify Locally Advanced Rectal Cancer Patients at High Risk of Poor Response to Neoadjuvant Chemoradiotherapy.

Published in:

Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.778781

By:

De Mattia, Elena;
Canzonieri, Vincenzo;
Polesel, Jerry;
Mezzalira, Silvia;
Dalle Fratte, Chiara;
Dreussi, Eva;
Roncato, Rossana;
Bignucolo, Alessia;
Innocente, Roberto;
Belluco, Claudio;
Pucciarelli, Salvatore;
De Paoli, Antonino;
Palazzari, Elisa;
Toffoli, Giuseppe;
Cecchin, Erika

Publication type:

Article

Vitamin B6 Alleviates Lipopolysaccharide-induced Myocardial Injury by Ferroptosis and Apoptosis Regulation.

Published in:

Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.766820

By:

Shan, Meirong;
Yu, Xujie;
Li, Yajie;
Fu, Changning;
Zhang, Cheng

Publication type:

Article

Sanguinarine Reverses Pulmonary Vascular Remolding of Hypoxia-Induced PH via Survivin/HIF1α-Attenuating Kv Channels.

Published in:

Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.768513

By:

Fan, Fenling;
Zou, Yifan;
Wang, Yousen;
Zhang, Peng;
Wang, Xiaoyu;
Dart, Anthony M.;
Zou, Yuliang

Publication type:

Article

Practical Implementation of Artificial Intelligence-Based Deep Learning and Cloud Computing on the Application of Traditional Medicine and Western Medicine in the Diagnosis and Treatment of Rheumatoid Arthritis.

Published in:

Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.765435

By:

Wang, Shaohui;
Hou, Ya;
Li, Xuanhao;
Meng, Xianli;
Zhang, Yi;
Wang, Xiaobo

Publication type:

Article

Differential Effects of Treatment Strategies in Individuals With Chronic Ocular Surface Pain With a Neuropathic Component.

Published in:

Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.788524

By:

Patel, Sneh;
Mittal, Rhiya;
Felix, Elizabeth R.;
Sarantopoulos, Konstantinos D.;
Levitt, Roy C.;
Galor, Anat

Publication type:

Article

Emerging Role of PD-1/PD-L1 Inhibitors in Chronic Liver Diseases.

Published in:

Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.790963

By:

Singh, Vishakha;
Khurana, Amit;
Allawadhi, Prince;
Banothu, Anil Kumar;
Bharani, Kala Kumar;
Weiskirchen, Ralf

Publication type:

Article

Editorial: The Role of Neuroinflammation in Chronic Pain Development and Maintenance.

Published in:

2021

By:

De Logu, Francesco;
Boccella, Serena;
Guida, Francesca

Publication type:

Editorial

Approaches to Decrease Hyperglycemia by Targeting Impaired Hepatic Glucose Homeostasis Using Medicinal Plants.

Published in:

Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.809994

By:

Mata-Torres, Gerardo;
Andrade-Cetto, Adolfo;
Espinoza-Hernández, Fernanda

Publication type:

Article

An Inflammatory Response Related Gene Signature Associated with Survival Outcome and Gemcitabine Response in Patients with Pancreatic Ductal Adenocarcinoma.

Published in:

Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.778294

By:

Xiao, Zhijun;
Li, Jinyin;
Yu, Qian;
Zhou, Ting;
Duan, Jingjing;
Yang, Zhen;
Liu, Cuicui;
Xu, Feng

Publication type:

Article

Herbal Formula Longteng Decoction Promotes the Regression of Synovial Inflammation in Collagen-Induced Arthritis Mice by Regulating Type 2 Innate Lymphocytes.

Published in:

Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.778845

By:

Zhang, Huijie;
Liu, Juan;
Zhang, Pingxin;
Li, Dongyang;
Feng, Guiyu;
Huandike, Meiyier;
Sun, Song;
Chai, Limin;
Zhou, Jingwei

Publication type:

Article

Targeting MyD88 Downregulates Inflammatory Mediators and Pathogenic Processes in PBMC From DMARDs-Naïve Rheumatoid Arthritis Patients.

Published in:

Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.800220

By:

Ramirez-Perez, Sergio;
Oregon-Romero, Edith;
Reyes-Perez, Itzel Viridiana;
Bhattaram, Pallavi

Publication type:

Article

Cyclin-Dependent Kinase Inhibitors and Their Therapeutic Potential in Colorectal Cancer Treatment.

Published in:

Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.757120

By:

Thoma, Oana-Maria;
Neurath, Markus F.;
Waldner, Maximilian J.

Publication type:

Article

Physiologically Based Pharmacokinetic Modeling of Cefadroxil in Mouse, Rat, and Human to Predict Concentration–Time Profile at Infected Tissue.

Published in:

Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.692741

By:

Tan, Zhongxia;
Zhang, Youxi;
Wang, Chao;
Sun, Le

Publication type:

Article

AhR Antagonist Promotes Differentiation of Papillary Thyroid Cancer via Regulating circSH2B3/miR-4640-5P/IGF2BP2 Axis.

Published in:

Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.795386

By:

Sa, Ri;
Guo, Meiliang;
Liu, Danyan;
Guan, Feng

Publication type:

Article

What Is Valued Most by Patients With Type 2 Diabetes Mellitus When Selecting Second-Line Antihyperglycemic Medications in China.

Published in:

Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.802897

By:

Liu, Shimeng;
Liu, Jing;
Yu, Yijiang;
Si, Lei;
Tang, Chengxiang;
Liu, Zhigang;
Chen, Yingyao

Publication type:

Article

A Risk-Based Approach for Managing Aquaculture Used Oxytetracycline-Induced TetR in Surface Water Across Taiwan Regions.

Published in:

Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.803499

By:

Lu, Tien-Hsuan;
Chen, Chi-Yun;
Wang, Wei-Min;
Liao, Chung-Min

Publication type:

Article

Mitochondrial Targeting Therapeutics: Promising Role of Natural Products in Non-alcoholic Fatty Liver Disease.

Published in:

Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.796207

By:

Xu, Jingqi;
Shen, Jiayan;
Yuan, Ruolan;
Jia, Bona;
Zhang, Yiwen;
Wang, Sijian;
Zhang, Yi;
Liu, Mengyang;
Wang, Tao

Publication type:

Article

Total Flavone of Abelmoschus manihot Ameliorates TNBS-Induced Colonic Fibrosis by Regulating Th17/Treg Balance and Reducing Extracellular Matrix.

Published in:

Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.769793

By:

Qiao, Lichao;
Fang, Lei;
Zhu, Junyi;
Xiang, Yu;
Xu, Haixia;
Sun, Xueliang;
Chen, Hongjin;
Yang, Bolin

Publication type:

Article

Ultrasound-Guided Lauromacrogol Injection for the Treatment of Active Bleeding After Renal Biopsy.

Published in:

Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.723634

By:

Liu, Weizong;
Jin, Chunchun;
Lian, Qingshu;
Xu, Lifeng;
Lin, Zhanye;
Lu, Jianghao;
Gong, Xuehao

Publication type:

Article

Commentary: Neuroinflammatory In Vitro Cell Culture Models and the Potential Applications for Neurological Disorders.

Published in:

Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.792614

By:

Wang, Yufang;
Peng, Yilin;
Yan, He

Publication type:

Article

Qingwenzhike Prescription Alleviates Acute Lung Injury Induced by LPS via Inhibiting TLR4/NF-kB Pathway and NLRP3 Inflammasome Activation.

Published in:

Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.790072

By:

Zhang, Cai;
Wang, Xinran;
Wang, Chunguo;
He, Cheng;
Ma, Quantao;
Li, Jialin;
Wang, Weiling;
Xu, Yan-Tong;
Wang, Ting

Publication type:

Article

Host Factor Interaction Networks Identified by Integrative Bioinformatics Analysis Reveals Therapeutic Implications in COPD Patients With COVID-19.

Published in:

Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.718874

By:

Zheng, Wenjiang;
Wang, Ting;
Wu, Peng;
Yan, Qian;
Liu, Chengxin;
Wu, Hui;
Zhan, Shaofeng;
Liu, Xiaohong;
Jiang, Yong;
Zhuang, Hongfa

Publication type:

Article

Molecular and Clinical Aspects of COVID-19 Vaccines and Other Therapeutic Interventions Apropos Emerging Variants of Concern.

Published in:

Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.778219

By:

Islam, Khursheed Ul;
A-Elgadir, Thoraya Mohamed Elhassan;
Afaq, Sarah;
Ahmad, Tanveer;
Iqbal, Jawed

Publication type:

Article

Insulin-Like Growth Factor Binding Proteins in Kidney Disease.

Published in:

Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.807119

By:

Wang, Shuqiang;
Chi, Kun;
Wu, Di;
Hong, Quan

Publication type:

Article

The Effective Role of Natural Product Berberine in Modulating Oxidative Stress and Inflammation Related Atherosclerosis: Novel Insights Into the Gut-Heart Axis Evidenced by Genetic Sequencing Analysis.

Published in:

Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.764994

By:

Cao, Richard Y.;
Zhang, Ying;
Feng, Zhen;
Liu, Siyu;
Liu, Yifan;
Zheng, Hongchao;
Yang, Jian

Publication type:

Article

Epigenetic and Genetic Factors Associated With Opioid Use Disorder: Are These Relevant to African American Populations.

Published in:

Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.798362

By:

Blackwood, Christopher A.;
Cadet, Jean Lud

Publication type:

Article

The Hexosamine Biosynthetic Pathway Links Innate Inflammation With Epithelial-Mesenchymal Plasticity in Airway Remodeling.

Published in:

Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.808735

By:

Brasier, Allan R.;
Qiao, Dianhua;
Zhao, Yingxin

Publication type:

Article

Kidney Injury Following Ibuprofen and Acetaminophen: A Real-World Analysis of Post-Marketing Surveillance Data.

Published in:

Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.750108

By:

Shao, Qi-hui;
Yin, Xue-dong;
Liu, Hong-xia;
Zhao, Bin;
Huang, Jian-quan;
Li, Zhi-ling

Publication type:

Article

Elevated N-Glycosylation Contributes to the Cisplatin Resistance of Non-Small Cell Lung Cancer Cells Revealed by Membrane Proteomic and Glycoproteomic Analysis.

Published in:

Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.805499

By:

Zeng, Wenjuan;
Zheng, Shanshan;
Mao, Yonghong;
Wang, Shisheng;
Zhong, Yi;
Cao, Wei;
Su, Tao;
Gong, Meng;
Cheng, Jingqiu;
Zhang, Yong;
Yang, Hao

Publication type:

Article