Works in Frontiers in Pharmacology, 2025

Results: 1747

Loss of expression and function of Gβγ by GNB1 encephalopathy-associated L95P mutation of the Gβ<sub>1</sub> subunit.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1592012

By:

Reddy, Haritha P.;
Keren-Raifman, Tal;
Tabak, Galit;
Dascal, Nathan;
Yakubovich, Daniel

Publication type:

Article

Therapeutic effects and mechanisms of Fufang Longdan mixture on metabolic syndrome with psoriasis via miR-29a-5p/IGF-1R axis.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1585369

By:

Luo, Guangyun;
Kong, Xiangyi;
Wang, Fang;
Wang, Zhiming;
Zhang, Zhuo;
Cui, Huan;
Zhang, Yiwen;
Huang, Wen;
Yang, Xuesong;
Ye, Jianzhou

Publication type:

Article

Natural saponins and macrophage polarization: Mechanistic insights and therapeutic perspectives in disease management.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1584035

By:

Xiong, Beibei;
Wang, Huan;
Song, Yi-Xuan;
Lan, Wen-Ying;
Li, Jiangtao;
Wang, Fang

Publication type:

Article

An updated review deciphering the anticancer potential of pentacyclic triterpene lupeol and its nanoformulations.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1594901

By:

AlMousa, Lujain A.;
Pandey, Pratibha;
Lakhanpal, Sorabh;
Kyada, Ashish Kumar;
H, Malathi.;
Nayak, Priya Priyadarshini;
Hussain, Arif;
Hasan, Tarique Noorul;
Alagal, Reham I.;
Khan, Fahad

Publication type:

Article

Preparation, structural characterization and health benefits of polysaccharides from Rubus chingii Hu: a review.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1592046

By:

Shan, Chao;
Zhu, Yingjia;
Bi, Haizheng;
Wang, Xingyu;
Wang, Jingyuan;
Wang, Meng

Publication type:

Article

Corrigendum: Protective effects of Cordyceps militaris against hepatocyte apoptosis and liver fibrosis induced by high palmitic acid diet.

Published in:

2025

By:

Tsai, Wan-Ting;
Situmorang, Jiro Hasegawa;
Kuo, Wei-Wen;
Kuo, Chia-Hua;
Lin, Shinn-Zong;
Huang, Chih-Yang;
Ho, Tsung-Jung

Publication type:

Correction Notice

The role of transient receptor potential channels in chronic kidney disease-mineral and bone disorder.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1583487

By:

Zhang, Lerong;
Xu, Penghao;
Hao, Lele;
Wang, Lingling;
Xu, Yunkai;
Jiang, Chen

Publication type:

Article

The role of ERK1/2 signaling in diabetes: pathogenic and therapeutic implications.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1600251

By:

Xu, Hanlin;
Liu, Tao;
Dai, Yanfen;
Li, Na;
Cao, Zhanqi

Publication type:

Article

Investigation of Fructus sophorae extract 's therapeutic mechanism in atrophic vaginitis based on network pharmacology and experimental validation.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1571976

By:

Zheng, Jiarui;
Wang, Weiming;
Song, Wenting;
Zhang, Yehao;
Yao, Mingjiang;
Wang, Guangrui;
Huang, Zishan;
Li, Feng;
Ren, Junguo;
Lin, Li;
Fan, Xiaodi;
Liu, Jianxun

Publication type:

Article

Correlation analysis of pharmacokinetic parameters of docetaxel AUC and adverse reactions in breast cancer patients.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1563506

By:

Tang, Yongzhe;
Liu, Yamin;
Qin, Shengying;
Huai, Cong;
Zhang, Jin;
Ding, Weijie;
Fan, Junwei;
Wang, Jie;
Zhang, Xiaoqing

Publication type:

Article

CS-6-induced p62 accumulation exacerbates DNA damage in colorectal cancer.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1568339

By:

Gong, Yitong;
Dong, Menghan;
Feng, Xiaofei;
Zhang, Naiyu;
Cui, Xuehui;
Wang, Liushuyue;
Qi, Qi;
Kuok, Chiu-fai;
Jiang, Qingling;
Bi, Sixue

Publication type:

Article

Cuproptosis-related genes and agents: implications in tumor drug resistance and future perspectives.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1559236

By:

Xu, Lingwen;
Cao, Xiaolan;
Deng, Yuxiao;
Zhang, Bin;
Li, Xinzhi;
Liu, Wentao;
Ren, Wenjie;
Tang, Xuan;
Kong, Xiangyu;
Zhang, Daizhou

Publication type:

Article

An ethnopharmacological survey of herbal medicines use among pregnant and postpartum women in Souss Massa (Morocco).

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1567930

By:

Bouqoufi, Afaf;
Lahlou, Laila;
Ait El Hadj, Fatima;
Boujraf, Said;
Abdessadek, Mohammed;
Khabbal, Youssef

Publication type:

Article

Suppressing chondrocyte cuproptosis by syringaresinol-4- O - β -d-glucoside alleviates gouty arthritis.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1565422

By:

Fu, Shaotian;
Du, Han;
Ling, Xiao;
Wang, Hanyi;
Chen, Jianan;
Zhang, Hang;
Chen, Wugui;
Liu, Chengzhao;
Ma, Hailong;
Lin, Chengshou;
Ma, Peixiang;
Qin, An

Publication type:

Article

Target screening and optimization of candidate compounds for breast cancer treatment using bioinformatics and computational chemistry approaches.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1467504

By:

Xu, Jian;
Li, Xue;
Jia, Yiduo

Publication type:

Article

Recent advances in the development and application of colorectal cancer mouse models.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1553637

By:

Wang, Ting;
Chen, Zhen;
Zhang, Yuli;
Liu, Min;
Sui, Hua;
Tang, Qingfeng

Publication type:

Article

Construction and validation of a meropenem-induced liver injury risk prediction model: a multicenter case-control study.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1542554

By:

He, Yan;
Ke, Hongqin;
Zhu, Jianyong;
Yuan, Xin;
Li, Hongliang;
Wu, Wenwen;
Yang, Shuman;
Yu, Huibin

Publication type:

Article

Cosmeceutical application of extracts from the flowers, stems, and leaves of Buddleja davidii grown at different altitudes.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1551134

By:

Chen, Chih-Yu;
Wang, Guey-Horng;
Chang, Yu-Chi;
Liu, Singer;
Lin, Yueh-Te;
Lai, Yi-Lin;
Chung, Ying-Chien

Publication type:

Article

Sanqi oral solution alleviates podocyte apoptosis in experimental membranous nephropathy by mediating EMT through the ERK/CK2-α/β-catenin pathway.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1503961

By:

Wang, Xiaowan;
Wang, Juanjuan;
Zheng, Bidan;
Tian, Ruimin;
Huang, Lihua;
Mao, Wei;
Feng, Yi;
Liu, Bo;
Xu, Peng

Publication type:

Article

Case report: Analysis of the efficacy and safety of anti-infectious treatment for brain abscess caused by oral anaerobes.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1506879

By:

Tian, Chunfang;
Liu, Jingxian;
Chen, Zhiyu;
Li, Lixia

Publication type:

Article

Protective effects of Cordyceps militaris against hepatocyte apoptosis and liver fibrosis induced by high palmitic acid diet.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2024.1438997

By:

Tsai, Wan-Ting;
Situmorang, Jiro Hasegawa;
Kuo, Wei-Wen;
Kuo, Chia-Hua;
Lin, Shinn-Zong;
Huang, Chih-Yang;
Ho, Tsung-Jung

Publication type:

Article

Reduced abundance of Fusobacterium signifies cardiovascular benefits of sodium glucose cotransporter 2 inhibitor in type 2 diabetes: a single arm clinical trial.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1600464

By:

Yang, Shuhui;
Deng, Jiankun;
Weng, Xiaoxu;
Ma, Zhaojie;
Lin, Nie;
Xiao, Yili;
Zuo, Rui;
Hu, Yufei;
Zheng, Canbin;
Zeng, Xiaoshan;
Lin, Qimao;
Hou, Kaijian

Publication type:

Article

Prophylactic anticoagulant therapy is associated with improved survival in ICU patients with non-COVID-19 pneumonia: a retrospective cohort study.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1597885

By:

Hu, Haiming;
Zhu, Yixing;
Hu, Ruikang;
Zhao, Lijuan;
Zeng, Xiangwen;
Wu, Xue;
Qiu, Rui;
Nie, Yihao;
Sharma, Lokesh;
Chang, De

Publication type:

Article

Rutin ameliorates LPS-induced acute lung injury in mice by inhibiting the cGAS-STING-NLRP3 signaling pathway.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1590096

By:

Zhou, Xin;
Wang, Zhibin;
Wang, Yuting;
Xu, Guofeng;
Luo, Min;
Zhang, Mengwei;
Li, Yuying

Publication type:

Article

Advances in the prevalence and treatment of depression for adolescents: a review.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1574574

By:

Yin, Chunyu;
Xu, Mengting;
Zong, Zhiyuan

Publication type:

Article

Metformin improves intestinal ischemia-reperfusion injury by reducing the formation of mitochondrial associated endoplasmic reticulum membranes (MAMs) and inhibiting ferroptosis in intestinal cells.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1581085

By:

Zhao, Xu;
Yan, Likun;
Tian, Lifei;
Zhang, Xiaolong;
Liu, Ruiting;
Li, Zeyu

Publication type:

Article

Protective effects of AER-271 in acute-phase radiation-induced brain injury in rats: reduction of brain edema, inflammation, apoptosis and maintenance of blood-brain barrier integrity.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1534729

By:

Xiong, Yaozu;
Wang, Yifei;
Li, Mingyue;
Yu, Changhua;
Tong, Yusuo;
Xu, Xiaoting

Publication type:

Article

Cardiovascular toxicities associated with chimeric antigen receptor T-cell therapy.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1578157

By:

Liu, Jia-Hui;
Liu, Kun-Yao;
Zhao, Xiang;
Zhou, Xin;
Jiang, Yichuan

Publication type:

Article

Mangiferin mitigates dexamethasone-induced insulin resistance in rats: insight into vascular dysfunction and hepatic steatosis.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1572758

By:

Alsaedi, Abdullah Q.;
Nader, Manar A.;
El-Kashef, Dalia H.;
Abdelmageed, Marwa E.

Publication type:

Article

Investigation of Fructus sophorae extract 's therapeutic mechanism in atrophic vaginitis based on network pharmacology and experimental validation.

Published in:

Frontiers in Pharmacology, 2025, p. N.PAG, doi. 10.3389/fphar.2025.1571976

By:

Zheng, Jiarui;
Wang, Weiming;
Song, Wenting;
Zhang, Yehao;
Yao, Mingjiang;
Wang, Guangrui;
Huang, Zishan;
Li, Feng;
Ren, Junguo;
Lin, Li;
Fan, Xiaodi;
Liu, Jianxun

Publication type:

Article

Knowledge landscape of macrophage research in liver fibrosis: a bibliometric review of the literature from WoSCC.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1571879

By:

Li, Yanbo;
Cao, Zhengmin;
Lu, Yanping;
Lei, Chao;
Lyu, Wenliang

Publication type:

Article

Preventive beneficial effects of cannabidiol in a reserpine-induced progressive model of parkinsonism.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1539783

By:

Lima, Alvaro C.;
Bioni, Vinicius S.;
Becegato, Marcela S.;
Meier, Ywlliane;
Cunha, Débora M. G.;
Aguiar, Natan A.;
Gonçalves, Narriman;
Peres, Fernanda F.;
Zuardi, Antônio W.;
Hallak, Jaime E. C.;
Crippa, José A.;
Smaili, Soraya S.;
Abilio, Vanessa C.;
Silva, Regina H.

Publication type:

Article

Understanding dosage effects of traditional Chinese medicine using network analysis.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1534129

By:

Wu, Jiawei;
Guo, Dianjing

Publication type:

Article

Editorial: Identification of effective biomarkers for diagnosis and treatment of chronic kidney disease: integrating bioinformatics and pharmacological approaches.

Published in:

2025

By:

Srivastava, Swayam Prakash;
Kanasaki, Keizo

Publication type:

Editorial

Adjuvant treatment with Wu-Zi-Yan-Zong formula for abnormal sperm parameters associated with male infertility: a meta-analysis of randomized controlled trials.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1580705

By:

Cui, Feilun;
Zhang, Yueshi;
Fan, Yu

Publication type:

Article

20(S)-protopanaxadiol inhibits proliferation and induces apoptosis of acute myeloid leukemia cells via targeting Bcl-X<sub>L</sub> and MCL-1.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1530270

By:

Xu, Meng;
Hao, Feng;
Wu, Shuangshuang;
Qu, Zhanning;
Li, Junying;
Chen, Shuang;
Fang, Fang;
Zhao, Yundong;
Hu, Cheng

Publication type:

Article

Editorial: World No-Tobacco: effects of tobacco and nicotine on the brain.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1610178

By:

Souza, Isis Nem de Oliveira;
Balerio, Graciela N.;
Pandy, Vijayapandi;
Grilli, Massimo;
Neves, Gilda Angela

Publication type:

Article

Editorial: Plant and fungal extracts and metabolites in neurotherapy: exploring their pharmacology and potential clinical uses.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1602574

By:

Hao, Jian;
Lavrov, Igor;
Zhou, Xianhu

Publication type:

Article

Plant polysaccharides influence tumor development based on epigenetics: a review.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1588857

By:

Li, Cong;
Hu, Yuao;
Yang, Hua

Publication type:

Article

Therapeutic and protective approaches to combat Campylobacter jejuni infections.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1572616

By:

Sharafutdinov, Irshad;
Linz, Bodo;
Tegtmeyer, Nicole;
Backert, Steffen

Publication type:

Article

Gut microbiota: a new target for the prevention and treatment of insomnia using Chinese herbal medicines and their active components.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1572007

By:

Wu, Changmei;
Dou, Jinjin;
Song, Xiaoxue;
Yang, Fang;
Liu, Xuan;
Song, Weipeng;
Zhang, Xiwu

Publication type:

Article

Curcumin: a potential anti-photoaging agent.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1559032

By:

Nie, Yuhong;
Li, Yiming

Publication type:

Article

Pachymic acid alleviates metabolic dysfunction-associated steatotic liver disease by inhibiting ferroptosis through PPARα.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1554850

By:

Ren, Guilin;
Lin, Yiyou;
Qiu, Jiannan;
Zhang, Congcong;
Chen, Lin;
Zhu, Linwensi;
Fan, Xiaohui;
Dou, Xiaobing;
Liu, Qingsheng

Publication type:

Article

The effect of therapeutic massage combined with conventional therapy in children with functional dyspepsia: a systematic review and meta-analysis.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1554438

By:

Lin, Shaohong;
Ye, Ruming;
Wu, Guanhong;
Wu, Lixia;
Lin, Ying;
Li, Dan;
Xie, Namei;
Zhang, Huiyue

Publication type:

Article

Adherence and persistence with istradefylline treatment in patients with Parkinson's disease in the United States.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1548631

By:

Joseph, Reversa;
Qian, Joyce;
Cummings, Hannah;
Chen, Yen-Hua;
Tewari, Shubham;
Soileau, Michael

Publication type:

Article

Assessing the therapeutic potential of rutin in alleviating symptoms of inflammatory bowel disease: a meta-analysis.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1539469

By:

Zou, Zhenkai;
Zhang, Fanglian;
Pan, Zhigang;
Xu, Jinyao;
Li, Xuanyi;
Sun, Xiangjun;
Wang, Xufeng;
Qin, Feng;
Abulizi, Abulikemu;
Chen, Qian;
Yan, Ruicheng

Publication type:

Article

Impact of polypharmacy phenogroups on different heart failure phenotypes in patients with chronic heart failure: a retrospective examination of real-world cohort.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1526112

By:

Sukik, Aseel;
Aboughalia, Ahmed Tarek;
Said Wali, Abdul Haseeb;
Al Radaideh, Amro;
Elsayed, Omar Mohamed;
Amer, Mohammed A.;
Abuodeh, Joud Said;
Adegboye, Oyelola A.;
Elzouki, AbdelNaser;
Danjuma, Mohammed Ibn-Mas'ud

Publication type:

Article

Efficacy and safety of puerarin injection as an adjunctive therapy for chronic heart failure: a systematic review and meta-analysis.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1516059

By:

Fan, Hesong;
Yang, Jingrong;
Wang, Huaizhe;
Zong, Shuli;
Qu, Yiwei;
Wang, Kefei;
Zhang, Fengyi;
Li, Xiao

Publication type:

Article

Multi - dimensional mechanism analysis of Choerospondias axillaris (Roxb.) Burtt et Hill in treating kidney stones: network pharmacology, molecular docking and in vitro experimental verification.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1501386

By:

Qiu, Meiqi;
Li, Senhua;
Zhang, Yu;
Yan, Jiaoxia;
Qin, Shiting;
Yin, Xijing;
Li, Yujun;
Zeng, Chunhui;
Yang, Ke

Publication type:

Article

Integrated metabolomics and network pharmacology analysis to reveal the mechanisms of Wenshenyang decoction in the treatment of chronic kidney disease.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1500463

By:

Jin, Ge;
Zhao, Zongjiang

Publication type:

Article