Works in Frontiers in Pharmacology, 2018

Results: 1329

The Role of Necroptosis in Cardiovascular Disease.

Published in:

Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.00721

By:

Zhe-Wei, Shi;
Li-Sha, Ge;
Yue-Chun, Li

Publication type:

Article

Safety Profile and Neurocognitive Function Following Acute 4-Fluoroamphetamine (4-FA) Administration in Humans.

Published in:

Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.00713

By:

de Sousa Fernandes Perna, Eliza B.;
Theunissen, Eef L.;
Dolder, Patrick C.;
Mason, Natasha L.;
Hutten, Nadia R. P. W.;
Toennes, Stefan W.;
Kuypers, Kim P. C.;
Ramaekers, Johannes G.

Publication type:

Article

Metabolomics Reveals the Efficacy of Caspase Inhibition for Saikosaponin D-Induced Hepatotoxicity.

Published in:

Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.00732

By:

Zhang, Qian-qian;
Huang, Wan-qiu;
Gao, Yi-qiao;
Han, Zhao-di;
Zhang, Wei;
Zhang, Zun-jian;
Xu, Feng-guo

Publication type:

Article

Homozygous CREM-IbΔC-X Overexpressing Mice Are a Reliable and Effective Disease Model for Atrial Fibrillation.

Published in:

Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.00706

By:

Stümpel, Frank T.;
Stein, Juliane;
Himmler, Kirsten;
Scholz, Beatrix;
Seidl, Matthias D.;
Skryabin, Boris V.;
Müller, Frank U.

Publication type:

Article

Psychedelic-Assisted Psychotherapy: A Paradigm Shift in Psychiatric Research and Development.

Published in:

Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.00733

By:

Schenberg, Eduardo Ekman

Publication type:

Article

c-Jun N-Terminal Kinases (JNKs) in Myocardial and Cerebral Ischemia/Reperfusion Injury.

Published in:

Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.00715

By:

Shvedova, Maria;
Anfinogenova, Yana;
Atochina-Vasserman, Elena N.;
Schepetkin, Igor A.;
Atochin, Dmitriy N.

Publication type:

Article

Proteomics Analysis of Monocyte-Derived Hepatocyte-Like Cells Identifies Integrin Beta 3 as a Specific Biomarker for Drug-Induced Liver Injury by Diclofenac.

Published in:

Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.00699

By:

Dragoi, Diana;
Benesic, Andreas;
Pichler, Garwin;
Kulak, Nils A.;
Bartsch, Harald S.;
Gerbes, Alexander L.

Publication type:

Article

Molecular Mechanism of Action of Trimethylangelicin Derivatives as CFTR Modulators.

Published in:

Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.00719

By:

Laselva, Onofrio;
Marzaro, Giovanni;
Vaccarin, Christian;
Lampronti, Ilaria;
Tamanini, Anna;
Lippi, Giuseppe;
Gambari, Roberto;
Cabrini, Giulio;
Bear, Christine E.;
Chilin, Adriana;
Dechecchi, Maria C.

Publication type:

Article

Danhong Injection Reversed Cardiac Abnormality in Brain–Heart Syndrome via Local and Remote β-Adrenergic Receptor Signaling.

Published in:

Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.00692

By:

Orgah, John O.;
Yu, Jiahui;
Zhao, Tiechan;
Wang, Lingyan;
Yang, Mingzhu;
Zhang, Yan;
Fan, Guanwei;
Zhu, Yan

Publication type:

Article

Identifying the Species of Seeds in Traditional Chinese Medicine Using DNA Barcoding.

Published in:

Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.00701

By:

Xiong, Chao;
Sun, Wei;
Li, Jingjian;
Yao, Hui;
Shi, Yuhua;
Wang, Ping;
Huang, Bisheng;
Shi, Linchun;
Liu, Di;
Hu, Zhigang;
Chen, Shilin

Publication type:

Article

Ethnopharmacology of Love.

Published in:

Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.00567

By:

Leonti, Marco;
Casu, Laura

Publication type:

Article

Identification of <italic>Ligularia</italic> Herbs Using the Complete Chloroplast Genome as a Super-Barcode.

Published in:

Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.00695

By:

Chen, Xinlian;
Zhou, Jianguo;
Cui, Yingxian;
Wang, Yu;
Duan, Baozhong;
Yao, Hui

Publication type:

Article

Design of Diarylheptanoid Derivatives as Dual Inhibitors Against Class IIa Histone Deacetylase and β-amyloid Aggregation.

Published in:

Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.00708

By:

Chen, Liang-Chieh;
Tseng, Hui-Ju;
Liu, Chang-Yi;
Huang, Yun-Yi;
Yen, Cheng-Chung;
Weng, Jing-Ru;
Lu, Yeh-Lin;
Hou, Wen-Chi;
Lin, Tony E.;
Pan, I-Horng;
Huang, Kuo-Kuei;
Huang, Wei-Jan;
Hsu, Kai-Cheng

Publication type:

Article

A Method for Rapid Screening of Anilide-Containing AMPK Modulators Based on Computational Docking and Biological Validation.

Published in:

Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.00710

By:

Mok, Simon W. F.;
Zeng, Wu;
Niu, Yuzhen;
Coghi, Paolo;
Wu, Yujun;
Sin, Wai Man;
Ng, Sio Ian;
Gordillo-Martínez, Flora;
Gao, Jia Yin;
Law, Betty Y. K.;
Liu, Liang;
Yao, Xiaojun;
Wong, Vincent K. W.

Publication type:

Article

Multiple Sessions of Transcranial Direct Current Stimulation (tDCS) Reduced Craving and Relapses for Alcohol Use: A Randomized Placebo-Controlled Trial in Alcohol Use Disorder.

Published in:

Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.00716

By:

Klauss, Jaisa;
Anders, Quézia S.;
Felippe, Luna V.;
Nitsche, Michael A.;
Nakamura-Palacios, Ester M.

Publication type:

Article

Haplotypic and Genotypic Association of Catechol-<italic>O</italic>-Methyltransferase rs4680 and rs4818 Polymorphisms and Treatment Resistance in Schizophrenia.

Published in:

Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.00705

By:

Sagud, Marina;
Tudor, Lucija;
Uzun, Suzana;
Perkovic, Matea Nikolac;
Zivkovic, Maja;
Konjevod, Marcela;
Kozumplik, Oliver;
Vuksan Cusa, Bjanka;
Svob Strac, Dubravka;
Rados, Iva;
Mimica, Ninoslav;
Mihaljevic Peles, Alma;
Nedic Erjavec, Gordana;
Pivac, Nela

Publication type:

Article

Will Widespread Synthetic Opioid Consumption Induce Epigenetic Consequences in Future Generations?

Published in:

Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.00702

By:

Gilardi, Federica;
Augsburger, Marc;
Thomas, Aurelien

Publication type:

Article

Combining Zebrafish and CRISPR/Cas9: Toward a More Efficient Drug Discovery Pipeline.

Published in:

Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.00703

By:

Cornet, Carles;
Di Donato, Vincenzo;
Terriente, Javier

Publication type:

Article

Proanthocyanidin Polymer-Rich Fraction of <italic>Stryphnodendron adstringens</italic> Promotes <italic>in Vitro</italic> and <italic>in Vivo</italic> Cancer Cell Death via Oxidative Stress.

Published in:

Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.00694

By:

Kaplum, Vanessa;
Ramos, Anelise C.;
Consolaro, Marcia E. L.;
Fernandez, Maria A.;
Ueda-Nakamura, Tânia;
Dias-Filho, Benedito P.;
Silva, Sueli de Oliveira;
de Mello, João C. P.;
Nakamura, Celso V.

Publication type:

Article

Association Between Cholangiocarcinoma and Proton Pump Inhibitors Use: A Nested Case-Control Study.

Published in:

Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.00718

By:

Peng, Yen-Chun;
Lin, Cheng-Li;
Hsu, Wan-Yun;
Chow, Wai-Keung;
Lee, Show-Wu;
Yeh, Hong-Zen;
Chen, Chia-Chang;
Kao, Chia-Hung

Publication type:

Article

Pharmacodynamics of the Glutamate Receptor Antagonists in the Rat Barrel Cortex.

Published in:

Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.00698

By:

Vinokurova, Daria;
Zakharov, Andrey V.;
Lebedeva, Julia;
Burkhanova, Gulshat F.;
Chernova, Kseniya A.;
Lotfullina, Nailya;
Khazipov, Rustem;
Valeeva, Guzel

Publication type:

Article

Trace Amine-Associated Receptors as Novel Therapeutic Targets for Immunomodulatory Disorders.

Published in:

Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.00680

By:

Christian, Sherri L.;
Berry, Mark D.

Publication type:

Article

Master Regulators Connectivity Map: A Transcription Factors-Centered Approach to Drug Repositioning.

Published in:

Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.00697

By:

De Bastiani, Marco A.;
Pfaffenseller, Bianca;
Klamt, Fabio

Publication type:

Article

How Tumor Cells Choose Between Epithelial-Mesenchymal Transition and Autophagy to Resist Stress—Therapeutic Implications.

Published in:

Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.00714

By:

Marcucci, Fabrizio;
Rumio, Cristiano

Publication type:

Article

Inhibition of RAGE Attenuates Cigarette Smoke-Induced Lung Epithelial Cell Damage via RAGE-Mediated Nrf2/DAMP Signaling.

Published in:

Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.00684

By:

Lee, Hanbyeol;
Lee, Jooyeon;
Hong, Seok-Ho;
Rahman, Irfan;
Yang, Se-Ran

Publication type:

Article

Chronic Use of Statins and Their Effect on Prevention of Post-Endoscopic Retrograde Cholangiopancreatography Pancreatitis.

Published in:

Frontiers in Pharmacology, 2018, p. 1, doi. 10.3389/fphar.2018.00704

By:

Mahamid, Mahmud;
Watad, Abdulla;
Bragazzi, Nicola L.;
Wengrower, Dov;
Wolff, Julie;
Livovsky, Dan;
Amital, Howard;
Adawi, Mohammad;
Goldin, Eran

Publication type:

Article

The IGF2/IGF1R/Nanog Signaling Pathway Regulates the Proliferation of Acute Myeloid Leukemia Stem Cells.

Published in:

Frontiers in Pharmacology, 2018, p. 1, doi. 10.3389/fphar.2018.00687

By:

Dan-dan Xu;
Ying Wang;
Peng-jun Zhou;
Shu-rong Qin;
Rong Zhang;
Yi Zhang;
Xue Xue;
Jianping Wang;
Xia Wang;
Hong-ce Chen;
Xiao Wang;
Yu-wei Pan;
Li Zhang;
Hai-zhao Yan;
Qiu-ying Liu;
Zhong Liu;
Su-hong Chen;
Hong-yuan Chen;
Yi-fei Wang

Publication type:

Article

Patient-Specific iPSC-Based Models of Huntington's Disease as a Tool to Study Store-Operated Calcium Entry Drug Targeting.

Published in:

Frontiers in Pharmacology, 2018, p. 1, doi. 10.3389/fphar.2018.00696

By:

Vigont, Vladimir;
Nekrasov, Evgeny;
Shalygin, Alexey;
Gusev, Konstantin;
Klushnikov, Sergey;
Illarioshkin, Sergey;
Lagarkova, Maria;
Kiselev, Sergey L.;
Kaznacheyeva, Elena

Publication type:

Article

Supplemented Use of Pre-, Pro-, and Synbiotics in Severe Acute Pancreatitis: An Updated Systematic Review and Meta-Analysis of 13 Randomized Controlled Trials.

Published in:

Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.00690

By:

Tian, Xu;
Pi, Yuan-Ping;
Liu, Xiao-Ling;
Chen, Hui;
Chen, Wei-Qing

Publication type:

Article

Specnuezhenide Decreases Interleukin-1β-Induced Inflammation in Rat Chondrocytes and Reduces Joint Destruction in Osteoarthritic Rats.

Published in:

Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.00700

By:

Ma, Chiyuan;
Zhou, Xiaopeng;
Xu, Kai;
Wang, Linyan;
Yang, Yute;
Wang, Wei;
Liu, An;
Ran, Jisheng;
Yan, Shigui;
Wu, Haobo;
Wu, Lidong

Publication type:

Article

PPARβ/δ Agonist GW501516 Inhibits Tumorigenicity of Undifferentiated Nasopharyngeal Carcinoma in C666-1 Cells by Promoting Apoptosis.

Published in:

Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.00648

By:

Ji, Yangyang;
Li, Hui;
Wang, Fang;
Gu, Linglan

Publication type:

Article

<italic>Rhus coriaria</italic> L. (Sumac) Evokes Endothelium-Dependent Vasorelaxation of Rat Aorta: Involvement of the cAMP and cGMP Pathways.

Published in:

Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.00688

By:

Anwar, Mohammad A.;
Samaha, Ali A.;
Baydoun, Safaa;
Iratni, Rabah;
Eid, Ali H.

Publication type:

Article

Screening of Combinatorial Quality Markers for Natural Products by Metabolomics Coupled With Chemometrics. A Case Study on Pollen Typhae.

Published in:

Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.00691

By:

Ding, Mingyan;
Jiang, Yan;
Yu, Xiean;
Zhang, Dong;
Li, Jin;
Wang, Hui;
Shen, Jiayuan;
Gao, Xiu-mei;
Chang, Yan-xu

Publication type:

Article

Insight Into the Molecular Dynamic Simulation Studies of Reactive Oxygen Species in Native Skin Membrane.

Published in:

Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.00644

By:

Yadav, Dharmendra K.;
Kumar, Surendra;
Choi, Eun-Ha;
Sharma, Praveen;
Misra, Sanjeev;
Kim, Mi-Hyun

Publication type:

Article

2′-<italic>O</italic>-Galloylhyperin Isolated From <italic>Pyrola incarnata</italic> Fisch. Attenuates LPS-Induced Inflammatory Response by Activation of SIRT1/Nrf2 and Inhibition of the NF-κB Pathways <italic>in Vitro</italic> and <italic>Vivo</italic>

Published in:

Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.00679

By:

Wang, Peng;
Gao, Chang;
Guo, Na;
Zhang, Sun-Dong;
Wang, Wei;
Yao, Li-Ping;
Zhang, Jing;
Efferth, Thomas;
Fu, Yu-Jie

Publication type:

Article

Tramadol’s Inhibitory Effects on Sexual Behavior: Pharmacological Studies in Serotonin Transporter Knockout Rats.

Published in:

Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.00676

By:

Esquivel-Franco, Diana C.;
Olivier, Berend;
Waldinger, Marcel D.;
Gutiérrez-Ospina, Gabriel;
Olivier, Jocelien D. A.

Publication type:

Article

Coenzyme Q10 or Creatine Counteract Pravastatin-Induced Liver Redox Changes in Hypercholesterolemic Mice.

Published in:

Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.00685

By:

Marques, Ana C.;
Busanello, Estela N. B.;
de Oliveira, Diogo N.;
Catharino, Rodrigo R.;
Oliveira, Helena C. F.;
Vercesi, Anibal E.

Publication type:

Article

Chuanxiong Formulae for Migraine: A Systematic Review and Meta-Analysis of High-Quality Randomized Controlled Trials.

Published in:

Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.00589

By:

Shan, Chun-Shuo;
Xu, Qing-Qing;
Shi, Yi-Hua;
Wang, Yong;
He, Zhang-Xin;
Zheng, Guo-Qing

Publication type:

Article

A Systematic Review on Non-mammalian Models in Epilepsy Research.

Published in:

Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.00655

By:

Johan Arief, Muhammad Faiz;
Choo, Brandon Kar Meng;
Yap, Jia Ling;
Kumari, Yatinesh;
Shaikh, Mohd Farooq

Publication type:

Article

Saponins From <italic>Paris forrestii</italic> (Takht.) H. Li Display Potent Activity Against Acute Myeloid Leukemia by Suppressing the RNF6/AKT/mTOR Signaling Pathway.

Published in:

Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.00673

By:

Lu, Qin;
He, Yuanming;
Wang, Yuehu;
Gao, Li;
Zheng, Yunjing;
Zhang, Zubin;
Cao, Biyin;
Wang, Qi;
Mao, Xinliang;
Hu, Shaoyan

Publication type:

Article

Review and Meta-Analyses of TAAR1 Expression in the Immune System and Cancers.

Published in:

Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.00683

By:

Fleischer, Lisa M.;
Somaiya, Rachana D.;
Miller, Gregory M.

Publication type:

Article

Molecular Mechanisms of T Cells Activation by Dendritic Cells in Autoimmune Diseases.

Published in:

Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.00642

By:

Tai, Yu;
Wang, Qingtong;
Korner, Heinrich;
Zhang, Lingling;
Wei, Wei

Publication type:

Article

Discovery of the Consistently Well-Performed Analysis Chain for SWATH-MS Based Pharmacoproteomic Quantification.

Published in:

Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.00681

By:

Fu, Jianbo;
Tang, Jing;
Wang, Yunxia;
Cui, Xuejiao;
Yang, Qingxia;
Hong, Jiajun;
Li, Xiaoxu;
Li, Shuang;
Chen, Yuzong;
Xue, Weiwei;
Zhu, Feng

Publication type:

Article

<italic>OpenPVSignal</italic>: Advancing Information Search, Sharing and Reuse on Pharmacovigilance Signals via FAIR Principles and Semantic Web Technologies.

Published in:

Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.00609

By:

Natsiavas, Pantelis;
Boyce, Richard D.;
Jaulent, Marie-Christine;
Koutkias, Vassilis

Publication type:

Article

Epigallocatechin-3-Gallate Promotes the Growth of Mink Hair Follicles Through Sonic Hedgehog and Protein Kinase B Signaling Pathways.

Published in:

Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.00674

By:

Zhang, Haihua;
Nan, Weixiao;
Wang, Shiyong;
Song, Xingchao;
Si, Huazhe;
Li, Tong;
Li, Guangyu

Publication type:

Article

Gut-Sourced Vasoactive Intestinal Polypeptide Induced by the Activation of α7 Nicotinic Acetylcholine Receptor Substantially Contributes to the Anti-inflammatory Effect of Sinomenine in Collagen-Induced Arthritis.

Published in:

Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.00675

By:

Yue, MengFan;
Zhang, XinYu;
Dou, YanNong;
Wei, ZhiFeng;
Tao, Yu;
Xia, YuFeng;
Dai, Yue

Publication type:

Article

Population Pharmacokinetics of Vancomycin in Chinese ICU Neonates: Initial Dosage Recommendations.

Published in:

Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.00603

By:

Li, Zhi-ling;
Liu, Yi-xi;
Jiao, Zheng;
Qiu, Gang;
Huang, Jian-quan;
Xiao, Yu-bo;
Wu, Shu-jin;
Wang, Chen-yu;
Hu, Wen-juan;
Sun, Hua-jun

Publication type:

Article

Cornel Iridoid Glycoside Inhibits Tau Hyperphosphorylation via Regulating Cross-Talk Between GSK-3β and PP2A Signaling.

Published in:

Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.00682

By:

Yang, Cuicui;
Li, Xuelian;
Gao, Wenbin;
Wang, Qi;
Zhang, Li;
Li, Yali;
Li, Lin;
Zhang, Lan

Publication type:

Article

A Computational Systems Pharmacology Approach to Investigate Molecular Mechanisms of Herbal Formula Tian-Ma-Gou-Teng-Yin for Treatment of Alzheimer’s Disease.

Published in:

Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.00668

By:

Wang, Tianduanyi;
Wu, Zengrui;
Sun, Lixia;
Li, Weihua;
Liu, Guixia;
Tang, Yun

Publication type:

Article

Amelioration of Cognitive Deficit by Embelin in a Scopolamine-Induced Alzheimer’s Disease-Like Condition in a Rat Model.

Published in:

Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.00665

By:

Bhuvanendran, Saatheeyavaane;
Kumari, Yatinesh;
Othman, Iekhsan;
Shaikh, Mohd Farooq

Publication type:

Article