Works in Frontiers in Pharmacology, 2018

Results: 1329

The Role of Adenosine Receptors in Psychostimulant Addiction.

Published in:

Frontiers in Pharmacology, 2018, p. 1, doi. 10.3389/fphar.2017.00985

By:

Ballesteros-Yáñez, Inmaculada;
Castillo, Carlos A.;
Merighi, Stefania;
Gessi, Stefania

Publication type:

Article

Adenine Nucleotides Attenuate Murine T Cell Activation Induced by Concanavalin A or T Cell Receptor Stimulation.

Published in:

Frontiers in Pharmacology, 2018, p. 1, doi. 10.3389/fphar.2017.00986

By:

Shinohara, Yuria;
Tsukimoto, Mitsutoshi

Publication type:

Article

The Case for TAAR1 as a Modulator of Central Nervous System Function.

Published in:

Frontiers in Pharmacology, 2018, p. 1, doi. 10.3389/fphar.2017.00987

By:

Rutigliano, Grazia;
Accorroni, Alice;
Zucchi, Riccardo

Publication type:

Article

Steroidal Pyrimidines and Dihydrotriazines as Novel Classes of Anticancer Agents against Hormone-Dependent Breast Cancer Cells.

Published in:

Frontiers in Pharmacology, 2018, p. 1, doi. 10.3389/fphar.2017.00979

By:

Scherbakov, Alexander M.;
Komkov, Alexander V.;
Komendantova, Anna S.;
Yastrebova, Margarita A.;
Andreeva, Olga E.;
Shirinian, Valerii Z.;
Hajra, Alakananda;
Zavarzin, Igor V.;
Volkova, Yulia A.

Publication type:

Article

Corrigendum: Ginsenoside Rb1 Enhances Atherosclerotic Plaque Stability by Improving Autophagy and Lipid Metabolism in Macrophage Foam Cells.

Published in:

Frontiers in Pharmacology, 2018, p. 1, doi. 10.3389/fphar.2017.00964

By:

Qiao, Lei;
Zhang, Xue;
Liu, Minghao;
Liu, Xiaoling;
Dong, Mei;
Cheng, Jing;
Zhang, Xinyu;
Zhai, Chungang;
Song, Yu;
Lu, Huixia;
Chen, Wenqiang

Publication type:

Article

Traditional Herbal Medicine-Derived Sulforaphene LFS-01 Reverses Colitis in Mice by Selectively Altering the Gut Microbiota and Promoting Intestinal Gamma-Delta T Cells.

Published in:

Frontiers in Pharmacology, 2018, p. 1, doi. 10.3389/fphar.2017.00959

By:

Li, Ming;
Gao, Jiali;
Tang, Yan;
Liu, Meishuo;
Wu, Sijin;
Qu, Kunli;
Long, Xiangyu;
Li, Huajun;
Liu, Min;
Liu, Yinhui;
Yuan, Jieli;
Mao, Lei;
Liu, Yu;
Zheng, Xiliang;
Wang, Erkang;
Wang, Jin;
Yang, Yongliang

Publication type:

Article

Scutellarin Suppresses NLRP3 Inflammasome Activation in Macrophages and Protects Mice against Bacterial Sepsis.

Published in:

Frontiers in Pharmacology, 2018, p. 1, doi. 10.3389/fphar.2017.00975

By:

Liu, Yi;
Jing, Yan-Yun;
Zeng, Chen-Ying;
Li, Chen-Guang;
Xu, Li-Hui;
Yan, Liang;
Bai, Wen-Jing;
Zha, Qing-Bing;
Ouyang, Dong-Yun;
He, Xian-Hui

Publication type:

Article

Omeprazole Inhibits Cell Proliferation and Induces G0/G1 Cell Cycle Arrest through Up-regulating miR-203a-3p Expression in Barrett's Esophagus Cells.

Published in:

Frontiers in Pharmacology, 2018, p. 1, doi. 10.3389/fphar.2017.00968

By:

Hou, Yichao;
Hu, Qiang;
Huang, Jiao;
Xiong, Hua

Publication type:

Article

The Calcium-Induced Regulation in the Molecular and Transcriptional Circuitry of Human Inflammatory Response and Autoimmunity.

Published in:

Frontiers in Pharmacology, 2018, p. 1, doi. 10.3389/fphar.2017.00962

By:

de Seabra Rodrigues Dias, Ivo R.;
Mok, Simon W. F.;
Gordillo-Martínez, Flora;
Khan, Imran;
Hsiao, Wendy W. L.;
Law, Betty Y. K.;
Wong, Vincent K. W.;
Liu, Liang

Publication type:

Article

β-Sheet Breaker Peptide-HPYD for the Treatment of Alzheimer's Disease: Primary Studies on Behavioral Test and Transcriptional Profiling.

Published in:

Frontiers in Pharmacology, 2018, p. 1, doi. 10.3389/fphar.2017.00969

By:

Liu, Weiying;
Sun, Fengxian;
Wan, Moxin;
Jiang, Fang;
Bo, Xiangyu;
Lin, Laixiang;
Tang, Hua;
Xu, Shumei

Publication type:

Article

Socioeconomic Inequalities in Overweight and Obesity in Serbia: Data from 2013 National Health Survey.

Published in:

Frontiers in Pharmacology, 2018, p. 1, doi. 10.3389/fphar.2017.00967

By:

Marija, Sekulic;
Dragan, Vasiljevic;
Svetlana, Radevic;
Nela, Djonovic

Publication type:

Article

International Clinical Trials in Latin American and Caribbean Countries: Research and Development to Meet Local Health Needs.

Published in:

Frontiers in Pharmacology, 2018, p. 1, doi. 10.3389/fphar.2017.00961

By:

Silva, Ricardo E. da;
Amato, Angélica A.;
Guilhem, Dirce B.;
Carvalho, Marta R. de;
Novaes, Maria R. C. G.

Publication type:

Article

miR449a/SIRT1/PGC-1α Is Necessary for Mitochondrial Biogenesis Induced by T-2 Toxin.

Published in:

Frontiers in Pharmacology, 2018, p. 1, doi. 10.3389/fphar.2017.00954

By:

Ma, Shijie;
Zhao, Yurong;
Sun, Jianwei;
Mu, Peiqiang;
Deng, Yiqun

Publication type:

Article

SCD1 Confers Temozolomide Resistance to Human Glioma Cells via the Akt/GSK3β/β-Catenin Signaling Axis.

Published in:

Frontiers in Pharmacology, 2018, p. 1, doi. 10.3389/fphar.2017.00960

By:

Dai, Shuang;
Yan, Yuanliang;
Xu, Zhijie;
Zeng, Shuangshuang;
Qian, Long;
Huo, Lei;
Li, Xuejun;
Sun, Lunquan;
Gong, Zhicheng

Publication type:

Article

Stem Cell Metabolism in Cancer and Healthy Tissues: Pyruvate in the Limelight.

Published in:

Frontiers in Pharmacology, 2018, p. 1, doi. 10.3389/fphar.2017.00958

By:

Corbet, Cyril

Publication type:

Article

Caffeine Controls Glutamatergic Synaptic Transmission and Pyramidal Neuron Excitability in Human Neocortex.

Published in:

Frontiers in Pharmacology, 2018, p. 1, doi. 10.3389/fphar.2017.00899

By:

Kerkhofs, Amber;
Xavier, Ana C.;
da Silva, Beatriz S.;
Canas, Paula M.;
Idema, Sander;
Baayen, Johannes C.;
Ferreira, Samira G.;
Cunha, Rodrigo A.;
Mansvelder, Huibert D.

Publication type:

Article

Rimonabant Kills Colon Cancer Stem Cells without Inducing Toxicity in Normal Colon Organoids.

Published in:

Frontiers in Pharmacology, 2018, p. 1, doi. 10.3389/fphar.2017.00949

By:

Fiore, Donatella;
Ramesh, Prashanthi;
Proto, Maria C.;
Piscopo, Chiara;
Franceschelli, Silvia;
Anzelmo, Serena;
Medema, Jan P.;
Bifulco, Maurizio;
Gazzerro, Patrizia

Publication type:

Article

The Anti-atherosclerotic Effect of Paeonol against Vascular Smooth Muscle Cell Proliferation by Up-regulation of Autophagy via the AMPK/mTOR Signaling Pathway.

Published in:

Frontiers in Pharmacology, 2018, p. 1, doi. 10.3389/fphar.2017.00948

By:

Wu, Hongfei;
Song, Aiwei;
Hu, Wenjun;
Dai, Min

Publication type:

Article

Activation of Dopamine D1-D2 Receptor Complex Attenuates Cocaine Reward and Reinstatement of Cocaine-Seeking through Inhibition of DARPP-32, ERK, and ΔFosB.

Published in:

Frontiers in Pharmacology, 2018, p. 1, doi. 10.3389/fphar.2017.00924

By:

Hasbi, Ahmed;
Perreault, Melissa L.;
Shen, Maurice Y. F.;
Fan, Theresa;
Nguyen, Tuan;
Alijaniaram, Mohammed;
Banasikowski, Tomek J.;
Grace, Anthony A.;
O'Dowd, Brian F.;
Fletcher, Paul J.;
George, Susan R.

Publication type:

Article

Dibutyltin Dichloride Retards Leydig Cell Developmental Regeneration in Adult Rat Testis.

Published in:

Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.01320

By:

Huang, Xiande;
Ma, Taoye;
Yin, Yongsheng

Publication type:

Article

β-Elemene Synergizes With Gefitinib to Inhibit Stem-Like Phenotypes and Progression of Lung Cancer via Down-Regulating EZH2.

Published in:

Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.01413

By:

Cheng, Haibo;
Ge, Xiaoyin;
Zhuo, Shiqin;
Gao, Yanan;
Zhu, Bo;
Zhang, Junfeng;
Shang, Wenbin;
Xu, Dakang;
Ge, Weihong;
Shi, Liyun

Publication type:

Article

Structural Based Screening of Antiandrogen Targeting Activation Function-2 Binding Site.

Published in:

Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.01419

By:

Liu, Yangguang;
Wu, Meng;
Wang, Tianqi;
Xie, Yongli;
Cui, Xiangling;
He, Liujun;
He, Yang;
Li, Xiaoyu;
Liu, Mingliang;
Hu, Laixing;
Cen, Shan;
Zhou, Jinming

Publication type:

Article

Effect of Ninjin'yoeito on the Loss of Skeletal Muscle Function in Cancer-Bearing Mice.

Published in:

Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.01400

By:

Ohsawa, Masahiro;
Maruoka, Junya;
Inami, Chihiro;
Iwaki, Anna;
Murakami, Tomoyasu;
Ishikura, Kei-ichiro

Publication type:

Article

Pathophysiology of NSAID-Associated Intestinal Lesions in the Rat: Luminal Bacteria and Mucosal Inflammation as Targets for Prevention.

Published in:

Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.01340

By:

Colucci, Rocchina;
Pellegrini, Carolina;
Fornai, Matteo;
Tirotta, Erika;
Antonioli, Luca;
Renzulli, Cecilia;
Ghelardi, Emilia;
Piccoli, Elena;
Gentile, Daniela;
Benvenuti, Laura;
Natale, Gianfranco;
Fulceri, Federica;
Palazón-Riquelme, Pablo;
López-Castejón, Gloria;
Blandizzi, Corrado;
Scarpignato, Carmelo

Publication type:

Article

Editorial: Advances and Challenges in Nanomedicine.

Published in:

2018

By:

Hua, Susan;
Wu, Sherry Y.

Publication type:

Editorial

Multi-Component Herbal Products in the Prevention and Treatment of Chemotherapy-Associated Toxicity and Side Effects: A Review on Experimental and Clinical Evidences.

Published in:

Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.01394

By:

Fu, Bowen;
Wang, Ning;
Tan, Hor-Yue;
Li, Sha;
Cheung, Fan;
Feng, Yibin

Publication type:

Article

Corrigendum: Mequindox Induced Genotoxicity and Carcinogenicity in Mice.

Published in:

Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.01387

By:

Liu, Qianying;
Lei, Zhixin;
Wu, Qin;
Huang, Deyu;
Xie, Shuyu;
Wang, Xu;
Pan, Yuanhu;
Yuan, Zonghui

Publication type:

Article

Advances in Achieving Opioid Analgesia Without Side Effects.

Published in:

Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.01388

By:

Machelska, Halina;
Celik, Melih Ö.

Publication type:

Article

Tolerance, Variability and Pharmacokinetics of Albumin-Bound Paclitaxel in Chinese Breast Cancer Patients.

Published in:

Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.01372

By:

Li, Qingmei;
Zhang, Hong;
Zhu, Xiaoxue;
Liu, Chengjiao;
Wu, Min;
Li, Cuiyun;
Li, Xiaojiao;
Gao, Lei;
Ding, Yanhua

Publication type:

Article

Isoorientin Ameliorates APAP-Induced Hepatotoxicity via Activation Nrf2 Antioxidative Pathway: The Involvement of AMPK/Akt/GSK3β.

Published in:

Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.01334

By:

Fan, Xiaoye;
Lv, Hongming;
Wang, Lidong;
Deng, Xuming;
Ci, Xinxin

Publication type:

Article

Use of a Primary Epithelial Cell Screening Tool to Investigate Phage Therapy in Cystic Fibrosis.

Published in:

Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.01330

By:

Trend, Stephanie;
Chang, Barbara J.;
O'Dea, Mark;
Stick, Stephen M.;
Kicic, Anthony

Publication type:

Article

β-Arrestin Based Receptor Signaling Paradigms: Potential Therapeutic Targets for Complex Age-Related Disorders.

Published in:

Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.01369

By:

van Gastel, Jaana;
Hendrickx, Jhana O.;
Leysen, Hanne;
Santos-Otte, Paula;
Luttrell, Louis M.;
Martin, Bronwen;
Maudsley, Stuart

Publication type:

Article

Topiramate and Metformin Are Effective Add-On Treatments in Controlling Antipsychotic-Induced Weight Gain: A Systematic Review and Network Meta-Analysis.

Published in:

Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.01393

By:

Zhuo, Chuanjun;
Xu, Yong;
Liu, Sha;
Li, Jing;
Zheng, Qishi;
Gao, Xiangyang;
Li, Shen;
Jing, Rixing;
Song, Xueqin;
Yue, Weihua;
Zhou, Chunhua;
Upthegrove, Rachel

Publication type:

Article

The Connected Community Pharmacy: Benefits for Healthcare and Implications for Health Policy.

Published in:

Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.01352

By:

Goundrey-Smith, Stephen

Publication type:

Article

IFN-β Plays Both Pro- and Anti-inflammatory Roles in the Rat Cardiac Fibroblast Through Differential STAT Protein Activation.

Published in:

Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.01368

By:

Bolívar, Samir;
Anfossi, Renatto;
Humeres, Claudio;
Vivar, Raúl;
Boza, Pía;
Muñoz, Claudia;
Pardo-Jimenez, Viviana;
Olivares-Silva, Francisco;
Díaz-Araya, Guillermo

Publication type:

Article

Clinical Efficacy of a Novel Therapeutic Principle, Anakoinosis.

Published in:

Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.01357

By:

Heudobler, Daniel;
Rechenmacher, Michael;
Lüke, Florian;
Vogelhuber, Martin;
Klobuch, Sebastian;
Thomas, Simone;
Pukrop, Tobias;
Hackl, Christina;
Herr, Wolfgang;
Ghibelli, Lina;
Gerner, Christopher;
Reichle, Albrecht

Publication type:

Article

Corrigendum: Evaluation of Marbofloxacin in Beagle Dogs After Oral Dosing: Preclinical Safety Evaluation and Comparative Pharmacokinetics of Two Different Tablets.

Published in:

Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.01385

By:

Lei, Zhixin;
Liu, Qianying;
Yang, Bing;
Khaliq, Haseeb;
Ahmed, Saeed;
Fan, Bowen;
Cao, Jiyue;
He, Qigai

Publication type:

Article

In utero Exposure to Atrazine Disrupts Rat Fetal Testis Development.

Published in:

Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.01391

By:

Fang, Yinghui;
Ni, Chaobo;
Dong, Yaoyao;
Li, Huitao;
Wu, Siwen;
Li, Xiaoheng;
Lv, Yao;
Huang, Tongliang;
Lian, Qingquan;
Ge, Ren-shan

Publication type:

Article

Genetic Polymorphisms of TYMS, MTHFR, ATIC, MTR, and MTRR Are Related to the Outcome of Methotrexate Therapy for Rheumatoid Arthritis in a Chinese Population.

Published in:

Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.01390

By:

Lv, Shuang;
Fan, HuiZhen;
Li, Jiang;
Yang, Hui;
Huang, Jing;
Shu, XiaoMing;
Zhang, Lu;
Xu, Yuan;
Li, Xiaoya;
Zuo, Jieyu;
Xiao, Cheng

Publication type:

Article

Biomodulatory Treatment With Azacitidine, All- trans Retinoic Acid and Pioglitazone Induces Differentiation of Primary AML Blasts Into Neutrophil Like Cells Capable of ROS Production and Phagocytosis.

Published in:

Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.01380

By:

Klobuch, Sebastian;
Steinberg, Tim;
Bruni, Emanuele;
Mirbeth, Carina;
Heilmeier, Bernhard;
Ghibelli, Lina;
Herr, Wolfgang;
Reichle, Albrecht;
Thomas, Simone

Publication type:

Article

Gene Therapy for Cystic Fibrosis Lung Disease: Overcoming the Barriers to Translation to the Clinic.

Published in:

Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.01381

By:

Donnelley, Martin;
Parsons, David W.

Publication type:

Article

Cost-Utility Analysis of Venous Thromboembolism Prophylaxis Strategies for People Undergoing Elective Total Hip and Total Knee Replacement Surgeries in the English National Health Service.

Published in:

Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.01370

By:

Dawoud, Dalia M.;
Wonderling, David;
Glen, Jessica;
Lewis, Sedina;
Griffin, Xavier;
Hunt, Beverley J.;
Stansby, Gerard;
Reed, Michael;
Rossiter, Nigel;
Chahal, Jagjot Kaur;
Sharpin, Carlos;
Barry, Peter

Publication type:

Article

Osthole Synergizes With HER2 Inhibitor, Trastuzumab in HER2-Overexpressed N87 Gastric Cancer by Inducing Apoptosis and Inhibition of AKT-MAPK Pathway.

Published in:

Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.01392

By:

Yang, Yun;
Ren, Feng;
Tian, Ziyin;
Song, Wei;
Cheng, Binfeng;
Feng, Zhiwei

Publication type:

Article

Preventive Effect of Curcumin Against Chemotherapy-Induced Side-Effects.

Published in:

Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.01374

By:

Liu, Zhijun;
Huang, Pengyun;
Law, Siukan;
Tian, Haiyan;
Leung, Wingnang;
Xu, Chuanshan

Publication type:

Article

Bidirectional Role of β2-Adrenergic Receptor in Autoimmune Diseases.

Published in:

Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.01313

By:

Wu, Li;
Tai, Yu;
Hu, Shanshan;
Zhang, Mei;
Wang, Rui;
Zhou, Weijie;
Tao, Juan;
Han, Yongsheng;
Wang, Qingtong;
Wei, Wei

Publication type:

Article

Inositol-Requiring Enzyme 1 Alpha Endoribonuclease Specific Inhibitor STF-083010 Alleviates Carbon Tetrachloride Induced Liver Injury and Liver Fibrosis in Mice.

Published in:

Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.01344

By:

Chen, Qian-Qian;
Zhang, Cheng;
Qin, Ming-Qiang;
Li, Jian;
Wang, Hua;
Xu, De-Xiang;
Wang, Jian-Qing

Publication type:

Article

Necrostatin-1 Attenuates Trauma-Induced Mouse Osteoarthritis and IL-1β Induced Apoptosis via HMGB1/TLR4/SDF-1 in Primary Mouse Chondrocytes.

Published in:

Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.01378

By:

Liang, Shuang;
Lv, Zheng-tao;
Zhang, Jia-ming;
Wang, Yu-ting;
Dong, Yong-hui;
Wang, Zheng-gang;
Chen, Kun;
Cheng, Peng;
Yang, Qing;
Guo, Feng-jing;
Lu, Wei-wei;
Zhu, Wen-tao;
Chen, An-min

Publication type:

Article

Therapeutic Targets for Treatment of Heart Failure: Focus on GRKs and β-Arrestins Affecting βAR Signaling.

Published in:

Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.01336

By:

Mangmool, Supachoke;
Parichatikanond, Warisara;
Kurose, Hitoshi

Publication type:

Article

Value of Contrast-Enhanced Ultrasound and Acoustic Radiation Force Impulse Imaging for the Differential Diagnosis of Benign and Malignant Thyroid Nodules.

Published in:

Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.01363

By:

He, Yan;
Wang, Xiao Yan;
Hu, Qiao;
Chen, Xue Xue;
Ling, Bing;
Wei, Hai Ming

Publication type:

Article

A Multi-Mode Bioactive Agent Isolated From Ficus microcarpa L. Fill. With Therapeutic Potential for Type 2 Diabetes Mellitus.

Published in:

Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.01376

By:

Akhtar, Nosheen;
Jafri, Laila;
Green, Brian D;
Kalsoom, Saima;
Mirza, Bushra

Publication type:

Article