Works in Frontiers in Pharmacology, 2016

Results: 528

Comparison of Different Risk Classification Systems in 558 Patients with Gastrointestinal Stromal Tumors after R0-Resection.

Published in:

Frontiers in Pharmacology, 2016, v. 7, p. 1, doi. 10.3389/fphar.2016.00504

By:

Schmieder, Michael;
Henne-Bruns, Doris;
Mayer, Benjamin;
Knippschild, Uwe;
Rolke, Claudia;
Schwab, Matthias;
Kramer, Klaus;
Criscuolo, Domenico;
Kerpel-Fronius, Sandor;
Yadav, Awesh K.

Publication type:

Article

Identification of Febuxostat as a New Strong ABCG2 Inhibitor: Potential Applications and Risks in Clinical Situations.

Published in:

Frontiers in Pharmacology, 2016, v. 7, p. 1, doi. 10.3389/fphar.2016.00518

By:

Hiroshi Miyata;
Tappei Takada;
Yu Toyoda;
Hirotaka Matsuo;
Kimiyoshi Ichida;
Hiroshi Suzuki;
Michaelis, Martin;
Peng Hsiao

Publication type:

Article

Optimized Cocktail Phenotyping Study Protocol Using Physiological Based Pharmacokinetic Modeling and In silico Assessment of Metabolic Drug-Drug Interactions Involving Modafinil.

Published in:

Frontiers in Pharmacology, 2016, v. 7, p. 1, doi. 10.3389/fphar.2016.00517

By:

Rowland, Angela;
Mangoni, Arduino A.;
Hopkins, Ashley;
Sorich, Michael J.;
Rowland, Andrew;
Takato Hiranita;
Backes, Wayne Louis

Publication type:

Article

BNN27, a 17-Spiroepoxy Steroid Derivative, Interacts With and Activates p75 Neurotrophin Receptor, Rescuing Cerebellar Granule Neurons from Apoptosis.

Published in:

Frontiers in Pharmacology, 2016, v. 7, p. 1, doi. 10.3389/fphar.2016.00512

By:

Pediaditakis, Iosif;
Kourgiantaki, Alexandra;
Prousis, Kyriakos C.;
Potamitis, Constantinos;
Xanthopoulos, Kleanthis P.;
Zervou, Maria;
Calogeropoulou, Theodora;
Charalampopoulos, Ioannis;
Gravanis, Achille

Publication type:

Article

Blockade of Serotonin 5-HT2A Receptors Suppresses Behavioral Sensitization and Naloxone-Precipitated Withdrawal Symptoms in Morphine-Treated Mice.

Published in:

Frontiers in Pharmacology, 2016, v. 7, p. 1, doi. 10.3389/fphar.2016.00514

By:

Gang Pang;
Xian Wu;
Xinrong Tao;
Ruoying Mao;
Xueke Liu;
Yong-Mei Zhang;
Guangwu Li;
Stackman Jr., Robert W.;
Liuyi Dong;
Gongliang Zhang

Publication type:

Article

Sustained Contraction in Vascular Smooth Muscle by Activation of L-type Ca2+ Channels Does Not Involve Ca2+ Sensitization or Caldesmon.

Published in:

Frontiers in Pharmacology, 2016, v. 7, p. 1, doi. 10.3389/fphar.2016.00516

By:

Ets, Hillevi K.;
Chun Y. Seow;
Moreland, Robert S.

Publication type:

Article

Unnecessary Hysterectomy due to Menorrhagia and Disorders of Hemostasis: An Example of Overuse and Excessive Demand for Medical Services.

Published in:

Frontiers in Pharmacology, 2016, v. 7, p. 1, doi. 10.3389/fphar.2016.00507

By:

Djukic, Svetlana M.;
Lekovic, Danijela;
Jovic, Nikola;
Varjacic, Mirjana

Publication type:

Article

Geroprotective and Radioprotective Activity of Quercetin, (-)-Epicatechin, and Ibuprofen in Drosophila melanogaster.

Published in:

Frontiers in Pharmacology, 2016, v. 7, p. 1, doi. 10.3389/fphar.2016.00505

By:

Proshkina, Ekaterina;
Lashmanova, Ekaterina;
Dobrovolskaya, Eugenia;
Zemskaya, Nadezhda;
Kudryavtseva, Anna;
Shaposhnikov, Mikhail;
Moskalev, Alexey

Publication type:

Article

Peptides Derived from a Phage Display Library Inhibit Adhesion and Protect the Host against Infection by Paracoccidioides brasiliensis and Paracoccidioides lutzii.

Published in:

Frontiers in Pharmacology, 2016, v. 7, p. 1, doi. 10.3389/fphar.2016.00509

By:

de Oliveira, Haroldo C.;
Michaloski, Jussara S.;
da Silva, Julhiany F.;
Scorzoni, Liliana;
de Paula e Silva, Ana C. A.;
Marcos, Caroline M.;
Assato, Patrícia A.;
Yamazaki, Daniella S.;
Fusco-Almeida, Ana M.;
Giordano, Ricardo J.;
Mendes-Giannini, Maria J. S.

Publication type:

Article

A Novel Sensitive Method to Measure Catechol-O-Methyltransferase Activity Unravels the Presence of This Activity in Extracellular Vesicles Released by Rat Hepatocytes.

Published in:

Frontiers in Pharmacology, 2016, v. 7, p. 1, doi. 10.3389/fphar.2016.00501

By:

Casal, Enriqueta;
Palomo, Laura;
Cabrera, Diana;
Falcon-Perez, Juan M.

Publication type:

Article

The Blood Flow Shutdown Induced by Combretastatin A4 Impairs Gemcitabine Delivery in a Mouse Hepatocarcinoma.

Published in:

Frontiers in Pharmacology, 2016, v. 7, p. 1, doi. 10.3389/fphar.2016.00506

By:

Fruytier, Anne-Catherine;
Le Duff, Cecile S.;
Po, Chrystelle;
Magat, Julie;
Bouzin, Caroline;
Neveu, Marie-Aline;
Feron, Olivier;
Jordan, Benedicte F.;
Gallez, Bernard

Publication type:

Article

The Synergistic Enhancing-Memory Effect of Donepezil and S 38093 (a Histamine H3 Antagonist) Is Mediated by Increased Neural Activity in the Septo-hippocampal Circuitry in Middle-Aged Mice.

Published in:

Frontiers in Pharmacology, 2016, v. 7, p. 1, doi. 10.3389/fphar.2016.00492

By:

Sors, Aurore;
Krazem, Ali;
Kehr, Jan;
Yoshitake, Takashi;
Dominguez, Gaelle;
Henkous, Nadia;
Letondor, Claire;
Mocaer, Elisabeth;
Béracochéa, Daniel J.

Publication type:

Article

Selective Estrogen Receptor Modulators: Cannabinoid Receptor Inverse Agonists with Differential CB1 and CB2 Selectivity.

Published in:

Frontiers in Pharmacology, 2016, v. 7, p. 1, doi. 10.3389/fphar.2016.00503

By:

Franks, Lirit N.;
Ford, Benjamin M.;
Prather, Paul L.

Publication type:

Article

Development of an IgY Antibody-Based Immunoassay for the Screening of the CYP2E1 Inhibitor/Enhancer from Herbal Medicines.

Published in:

Frontiers in Pharmacology, 2016, v. 7, p. 1, doi. 10.3389/fphar.2016.00502

By:

Zhihui Jiang;
Xuemei Jiang;
Cui Li;
Huiting Xue;
Xiaoying Zhang

Publication type:

Article

Grape Seed Extract Attenuates Hepatitis C Virus Replication and Virus-Induced Inflammation.

Published in:

Frontiers in Pharmacology, 2016, v. 7, p. 1, doi. 10.3389/fphar.2016.00490

By:

Wei-Chun Chen;
Chin-Kai Tseng;
Bing-Hung Chen;
Chun-Kuang Lin;
Jin-Ching Lee

Publication type:

Article

Cardioprotective Effect of Ulmus wallichiana Planchon in β-Adrenergic Agonist Induced Cardiac Hypertrophy.

Published in:

Frontiers in Pharmacology, 2016, v. 7, p. 1, doi. 10.3389/fphar.2016.00510

By:

Syed, Anees A.;
Lahiri, Shibani;
Mohan, Divya;
Valicherla, Guru R.;
Gupta, Anand P.;
Kumar, Sudhir;
Maurya, Rakesh;
Bora, Himanshu K.;
Hanif, Kashif;
Gayen, Jiaur R.

Publication type:

Article

Improvement of Oral Bioavailability of Curcumin upon Microencapsulation with Methacrylic Copolymers.

Published in:

Frontiers in Pharmacology, 2016, v. 7, p. 1, doi. 10.3389/fphar.2016.00485

By:

Paolino, Donatella;
Vero, Ada;
Cosco, Donato;
Pecora, Tiziana M. G.;
Cianciolo, Simona;
Fresta, Massimo;
Pignatello, Rosario

Publication type:

Article

Anticonvulsant, Anxiolytic, and Sedative Activities of Verbena officinalis.

Published in:

Frontiers in Pharmacology, 2016, v. 7, p. 1, doi. 10.3389/fphar.2016.00499

By:

Khan, Abdul Waheed;
Khan, Arif-ullah;
Ahmed, Touqeer

Publication type:

Article

Astragaloside IV Attenuates Podocyte Apoptosis Mediated by Endoplasmic Reticulum Stress through Upregulating Sarco/Endoplasmic Reticulum Ca2+-ATPase 2 Expression in Diabetic Nephropathy.

Published in:

Frontiers in Pharmacology, 2016, v. 7, p. 1, doi. 10.3389/fphar.2016.00500

By:

Hengjiang Guo;
Aili Cao;
Shuang Chu;
Yi Wang;
Yingjun Zang;
Xiaodong Mao;
Hao Wang;
Yunman Wang;
Cheng Liu;
Xuemei Zhang;
Wen Peng

Publication type:

Article

Doxazosin Stimulates Galectin-3 Expression and Collagen Synthesis in HL-1 Cardiomyocytes Independent of Protein Kinase C Pathway.

Published in:

Frontiers in Pharmacology, 2016, v. 7, p. 1, doi. 10.3389/fphar.2016.00495

By:

Xiaoqian Qian;
Mingyang Li;
Wagner, Mary B.;
Guangping Chen;
Xiang Song

Publication type:

Article

Prognostic and Predictive Factors in Patients with Advanced Penile Cancer Receiving Salvage (2nd or Later Line) Systemic Treatment: A Retrospective, Multi-Center Study.

Published in:

Frontiers in Pharmacology, 2016, v. 7, p. 1, doi. 10.3389/fphar.2016.00487

By:

Buonerba, Carlo;
Di Lorenzo, Giuseppe;
Pond, Gregory;
Cartenì, Giacomo;
Scagliarini, Sarah;
Rozzi, Antonio;
Quevedo, Fernando J.;
Dorff, Tanya;
Nappi, Lucia;
Lanzetta, Gaetano;
Pagliaro, Lance;
Eigl, Bernhard J.;
Naik, Gurudatta;
Ferro, Matteo;
Galdiero, Mariano;
De Placido, Sabino;
Sonpavde, Guru

Publication type:

Article

Antinociceptive Effects of AGAP, a Recombinant Neurotoxic Polypeptide: Possible Involvement of the Tetrodotoxin-Resistant Sodium Channels in Small Dorsal Root Ganglia Neurons.

Published in:

Frontiers in Pharmacology, 2016, v. 7, p. 1, doi. 10.3389/fphar.2016.00496

By:

Chun-Li Li;
Xi-Fang Liu;
Gui-Xia Li;
Meng-qi Ban;
Jian-Zhao Chen;
Yong Cui;
Jing-Hai Zhang;
Chun-Fu Wu

Publication type:

Article

Rivaroxaban-Induced Hemorrhage Associated with ABCB1 Genetic Defect.

Published in:

Frontiers in Pharmacology, 2016, v. 7, p. 1, doi. 10.3389/fphar.2016.00494

By:

Lorenzini, Kuntheavy Ing;
Daali, Youssef;
Fontana, Pierre;
Desmeules, Jules;
Samer, Caroline

Publication type:

Article

P53-MDM2 Pathway: Evidences for A New Targeted Therapeutic Approach in B-Acute Lymphoblastic Leukemia.

Published in:

Frontiers in Pharmacology, 2016, v. 7, p. 1, doi. 10.3389/fphar.2016.00491

By:

Trino, Stefania;
De Luca, Luciana;
Laurenzana, Ilaria;
Caivano, Antonella;
Del Vecchio, Luigi;
Martinelli, Giovanni;
Musto, Pellegrino

Publication type:

Article

Prediction of Deoxypodophyllotoxin Disposition in Mouse, Rat, Monkey, and Dog by Physiologically Based Pharmacokinetic Model and the Extrapolation to Human.

Published in:

Frontiers in Pharmacology, 2016, v. 7, p. 1, doi. 10.3389/fphar.2016.00488

By:

Yang Chen;
Kaijing Zhao;
Fei Liu;
Qiushi Xie;
Zeyu Zhong;
Mingxing Miao;
Xiaodong Liu;
Li Liu

Publication type:

Article

Suppression of Medulloblastoma Lesions by Forced Migration of Preneoplastic Precursor Cells with Intracerebellar Administration of the Chemokine Cxcl3.

Published in:

Frontiers in Pharmacology, 2016, v. 7, p. 1, doi. 10.3389/fphar.2016.00484

By:

Ceccarelli, Manuela;
Micheli, Laura;
Tirone, Felice

Publication type:

Article

Bidirectional Effects of Cannabidiol on Contextual Fear Memory Extinction.

Published in:

Frontiers in Pharmacology, 2016, v. 7, p. 1, doi. 10.3389/fphar.2016.00493

By:

Chenchen Song;
Stevenson, Carl W.;
Guimaraes, Francisco S.;
Lee, Jonathan L. C.

Publication type:

Article

Role of Somatostatin in Preventing Post-endoscopic Retrograde Cholangiopancreatography (ERCP) Pancreatitis: An Update Meta-analysis.

Published in:

Frontiers in Pharmacology, 2016, v. 7, p. 1, doi. 10.3389/fphar.2016.00489

By:

Jing Hu;
Pei-Lin Li;
Tao Zhang;
Jin-Ping Chen;
Yao-Jun Hu;
Zheng Yu;
Jin-Peng Wang;
Dan Zhu;
Xiao-Fei Tong

Publication type:

Article

Targeting the SR-B1 Receptor as a Gateway for Cancer Therapy and Imaging.

Published in:

Frontiers in Pharmacology, 2016, v. 7, p. 1, doi. 10.3389/fphar.2016.00466

By:

Mooberry, Linda K.;
Sabnis, Nirupama A.;
Panchoo, Marlyn;
Nagarajan, Bhavani;
Lacko, Andras G.

Publication type:

Article

Metabolomic Study on Idiosyncratic Liver Injury Induced by Different Extracts of Polygonum multiflorum in Rats Integrated with Pattern Recognition and Enriched Pathways Analysis.

Published in:

Frontiers in Pharmacology, 2016, v. 7, p. 1, doi. 10.3389/fphar.2016.00483

By:

Rui-Lin Wang;
Mei-Hua Yang;
Chun-Yu Li;
Dan Gao;
Ming Niu;
Rui-Yu Li;
Cong-En Zhang;
Xiao-He Xiao;
Jia-Bo Wang;
Can Tu;
Hai-Zhu Zhang;
Rui-Sheng Li

Publication type:

Article

The Angiotensin-(1-7)/Mas Axis Counteracts Angiotensin II-Dependent and -Independent Pro-inflammatory Signaling in Human Vascular Smooth Muscle Cells.

Published in:

Frontiers in Pharmacology, 2016, v. 7, p. 1, doi. 10.3389/fphar.2016.00482

By:

Villalobos, Laura A.;
Hipólito-Luengo, Álvaro San;
Ramos-González, Mariella;
Cercas, Elena;
Vallejo, Susana;
Romero, Alejandra;
Romacho, Tania;
Sánchez-Ferrer, Carlos F.;
Peiró, Concepción;
Carraro, Raffaele

Publication type:

Article

Protective Effects of Pleurotus tuber-regium on Carbon-Tetrachloride Induced Testicular Injury in Sprague Dawley Rats.

Published in:

Frontiers in Pharmacology, 2016, v. 7, p. 1, doi. 10.3389/fphar.2016.00480

By:

Okolo, Kenneth O.;
Siminialayi, Iyeopu M.;
Orisakwe, Orish E.

Publication type:

Article

Silymarin Protects Mouse Liver and Kidney from Thioacetamide Induced Toxicity by Scavenging Reactive Oxygen Species and Activating PI3K-Akt Pathway.

Published in:

Frontiers in Pharmacology, 2016, v. 7, p. 1, doi. 10.3389/fphar.2016.00481

By:

Ghosh, Shatadal;
Sarkar, Abhijit;
Bhattacharyya, Sudip;
Sil, Parames C.

Publication type:

Article

Pharmacological Characterization of the Native Store-Operated Calcium Channels of Cortical Neurons from Embryonic Mouse Brain.

Published in:

Frontiers in Pharmacology, 2016, v. 7, p. 1, doi. 10.3389/fphar.2016.00486

By:

Chauvet, Sylvain;
Jarvis, Louis;
Chevallet, Mireille;
Shrestha, Niroj;
Groschner, Klaus;
Bouron, Alexandre;
Minke, Baruch;
Artalejo, Antonio R.

Publication type:

Article

Cynaropicrin: A Comprehensive Research Review and Therapeutic Potential As an Anti-Hepatitis C Virus Agent.

Published in:

Frontiers in Pharmacology, 2016, v. 7, p. 1, doi. 10.3389/fphar.2016.00472

By:

ELSEBAI, MAHMOUD F.;
MOCAN, ANDREI;
ATANASOV, ATANAS G.

Publication type:

Article

Chrysophanic Acid Suppresses Adipogenesis and Induces Thermogenesis by Activating AMP-Activated Protein Kinase Alpha In vivo and In vitro.

Published in:

Frontiers in Pharmacology, 2016, v. 7, p. 1, doi. 10.3389/fphar.2016.00476

By:

Hara Lim;
Jinbong Park;
Hye-Lin Kim;
Jong Wook Kang;
Mi-Young Jeong;
Dong-Hyun Youn;
Yunu Jung;
Yong-Il Kim;
Hyun-Ju Kim;
Kwang Seok Ahn;
Su-Jin Kim;
Seong-Kyu Choe;
Seung-Heon Hong;
Jae-Young Um

Publication type:

Article

Plant Protease Inhibitors in Therapeutics-Focus on Cancer Therapy.

Published in:

Frontiers in Pharmacology, 2016, v. 7, p. 1, doi. 10.3389/fphar.2016.00470

By:

Srikanth, Sandhya;
Zhong Chen

Publication type:

Article

Glioblastoma Stem-Like Cells: Characteristics, Microenvironment, and Therapy.

Published in:

Frontiers in Pharmacology, 2016, v. 7, p. 1, doi. 10.3389/fphar.2016.00477

By:

Yang Yi;
I-Yun Hsieh;
Xiaojia Huang;
Jie Li;
Wei Zhao

Publication type:

Article

Golden Needle Mushroom: A Culinary Medicine with Evidenced-Based Biological Activities and Health Promoting Properties.

Published in:

Frontiers in Pharmacology, 2016, v. 7, p. 1, doi. 10.3389/fphar.2016.00474

By:

Calyn Tang;
Pearl Ching-Xin Hoo;
Loh Teng-Hern Tan;
Priyia Pusparajah;
Tahir Mehmood Khan;
Learn-Han Lee;
Bey-Hing Goh;
Kok-Gan Chan

Publication type:

Article

Opportunities and Challenges for Drug Development: Public-Private Partnerships, Adaptive Designs and Big Data.

Published in:

Frontiers in Pharmacology, 2016, v. 7, p. 1, doi. 10.3389/fphar.2016.00461

By:

Yildirim, Oktay;
Gottwald, Matthias;
Schüler, Peter;
Michel, Martin C.

Publication type:

Article

IL-1 Inhibition in Systemic Juvenile Idiopathic Arthritis.

Published in:

Frontiers in Pharmacology, 2016, v. 7, p. 1, doi. 10.3389/fphar.2016.00467

By:

Giancane, Gabriella;
Minoia, Francesca;
Davì, Sergio;
Bracciolini, Giulia;
Consolaro, Alessandro;
Ravelli, Angelo

Publication type:

Article

Protocatechuic Aldehyde Attenuates Cisplatin-Induced Acute Kidney Injury by Suppressing Nox-Mediated Oxidative Stress and Renal Inflammation.

Published in:

Frontiers in Pharmacology, 2016, v. 7, p. 1, doi. 10.3389/fphar.2016.00479

By:

Li Gao;
Wei-Feng Wu;
Lei Dong;
Gui-Ling Ren;
Hai-Di Li;
Qin Yang;
Xiao-Feng Li;
Tao Xu;
Zeng Li;
Bao-Ming Wu;
Tao-Tao Ma;
Cheng Huang;
Yan Huang;
Lei Zhang;
Xiongwen Lv;
Jun Li;
Xiao-Ming Meng

Publication type:

Article

Formulation and In vitro Interaction of Rhodamine-B Loaded PLGA Nanoparticles with Cardiac Myocytes.

Published in:

Frontiers in Pharmacology, 2016, v. 7, p. 1, doi. 10.3389/fphar.2016.00458

By:

Jonderian, Antranik;
Maalouf, Rita

Publication type:

Article

Mitragyna speciosa Leaf Extract Exhibits Antipsychotic-Like Effect with the Potential to Alleviate Positive and Negative Symptoms of Psychosis in Mice.

Published in:

Frontiers in Pharmacology, 2016, v. 7, p. 1, doi. 10.3389/fphar.2016.00464

By:

Vijeepallam, Kamini;
Pandy, Vijayapandi;
Kunasegaran, Thubasni;
Murugan, Dharmani D.;
Naidu, Murali

Publication type:

Article

Corrigendum: Pazopanib in Metastatic Renal Cancer: A "Real-World" Experience at National Cancer Institute "Fondazione G. Pascale".

Published in:: 2016
Publication type:: Correction Notice

The Antibiotic Drug Tigecycline: A Focus on its Promising Anticancer Properties.

Published in:

Frontiers in Pharmacology, 2016, v. 7, p. 1, doi. 10.3389/fphar.2016.00473

By:

Zhijie Xu;
Yuanliang Yan;
Zhi Li;
Long Qian;
Zhicheng Gong

Publication type:

Article

Pharmacogenomic Study Reveals New Variants of Drug Metabolizing Enzyme and Transporter Genes Associated with Steady-State Plasma Concentrations of Risperidone and 9-Hydroxyrisperidone in Thai Autism Spectrum Disorder Patients.

Published in:

Frontiers in Pharmacology, 2016, v. 7, p. 1, doi. 10.3389/fphar.2016.00475

By:

Sadeep Medhasi;
Darawan Pinthong;
Ekawat Pasomsub;
Natchaya Vanwong;
Nattawat Ngamsamut;
Apichaya Puangpetch;
Monpat Chamnanphon;
Yaowaluck Hongkaew;
Jirawat Pratoomwun;
Penkhae Limsila;
Chonlaphat Sukasem

Publication type:

Article

Anti-Proliferative and Apoptosis-Inducing Effect of Theabrownin against Non-small Cell Lung Adenocarcinoma A549 Cells.

Published in:

Frontiers in Pharmacology, 2016, v. 7, p. 1, doi. 10.3389/fphar.2016.00465

By:

Feifei Wu;
Li Zhou;
Wangdong Jin;
Weiji Yang;
Ying Wang;
Bo Yan;
Wenlin Du;
Qiang Zhang;
Lei Zhang;
Yonghua Guo;
Jin Zhang;
Shan, Letian;
Efferth, Thomas

Publication type:

Article

Polyunsaturated Fatty Acids and Their Derivatives: Therapeutic Value for Inflammatory, Functional Gastrointestinal Disorders, and Colorectal Cancer.

Published in:

Frontiers in Pharmacology, 2016, v. 7, p. 1, doi. 10.3389/fphar.2016.00459

By:

Michalak, Arkadiusz;
Mosiñska, Paula;
Fichna, Jakub

Publication type:

Article

Cysteinyl Leukotrienes Pathway Genes, Atopic Asthma and Drug Response: From Population Isolates to Large Genome-Wide Association Studies.

Published in:

Frontiers in Pharmacology, 2016, v. 7, p. 1, doi. 10.3389/fphar.2016.00299

By:

Thompson, Miles D.;
Capra, Valerie;
Clunes, Mark T.;
Rovati, G. E.;
Stankova, Jana;
Maj, Mary C.;
Duffy, David A.

Publication type:

Article