Works matching IS 1567567X AND DT 2025 AND VI 52 AND IP 2

Results: 10

Interoccasion variability in population pharmacokinetic models: identifiability, influence, interdependencies and derived study design recommendations.

Published in:

Journal of Pharmacokinetics & Pharmacodynamics, 2025, v. 52, n. 2, p. 1, doi. 10.1007/s10928-025-09966-7

By:

Behrens, Emily;
Wicha, Sebastian G.

Publication type:

Article

Advancing inclusive healthcare through PBPK modelling: predicting the impact of CYP genotypes and enzyme ontogenies on infant exposures of venlafaxine and its active metabolite O-desmethylvenlafaxine in lactation.

Published in:

Journal of Pharmacokinetics & Pharmacodynamics, 2025, v. 52, n. 2, p. 1, doi. 10.1007/s10928-025-09969-4

By:

Pan, Xian;
Rowland Yeo, Karen

Publication type:

Article

Information-theoretic evaluation of covariate distributions models.

Published in:

Journal of Pharmacokinetics & Pharmacodynamics, 2025, v. 52, n. 2, p. 1, doi. 10.1007/s10928-025-09968-5

By:

Hartung, Niklas;
Khatova, Aleksandra

Publication type:

Article

Imputation of missing clock times – application to procalcitonin concentration time course after birth.

Published in:

Journal of Pharmacokinetics & Pharmacodynamics, 2025, v. 52, n. 2, p. 1, doi. 10.1007/s10928-025-09965-8

By:

Bokor, Abigail J.;
Holford, Nick;
Hannam, Jacqueline A.

Publication type:

Article

Sampling from covariate distribution may not always be necessary in PK/PD simulations: illustrative examples with antibiotics.

Published in:

Journal of Pharmacokinetics & Pharmacodynamics, 2025, v. 52, n. 2, p. 1, doi. 10.1007/s10928-025-09967-6

By:

Liu, Feiyan;
Cheng, Zeneng;
Li, Sanwang;
Xie, Feifan

Publication type:

Article

Defining preclinical efficacy with the DNAPK inhibitor AZD7648 in combination with olaparib: a minimal systems pharmacokinetic–pharmacodynamic model.

Published in:

Journal of Pharmacokinetics & Pharmacodynamics, 2025, v. 52, n. 2, p. 1, doi. 10.1007/s10928-025-09962-x

By:

DeJongh, Joost;
Cadogan, Elaine;
Davies, Michael;
Ramos-Montoya, Antonio;
Smith, Aaron;
van Steeg, Tamara;
Richards, Ryan

Publication type:

Article

The impact of misspecified covariate models on inclusion and omission bias when using fixed effects and full random effects models.

Published in:

Journal of Pharmacokinetics & Pharmacodynamics, 2025, v. 52, n. 2, p. 1, doi. 10.1007/s10928-025-09964-9

By:

Nyberg, Joakim;
Jonsson, E. Niclas

Publication type:

Article

Defining preclinical efficacy with the DNAPK inhibitor AZD7648 in combination with olaparib: a minimal systems pharmacokinetic–pharmacodynamic model.

Published in:

Journal of Pharmacokinetics & Pharmacodynamics, 2025, v. 52, n. 2, p. 1, doi. 10.1007/s10928-025-09962-x

By:

DeJongh, Joost;
Cadogan, Elaine;
Davies, Michael;
Ramos-Montoya, Antonio;
Smith, Aaron;
van Steeg, Tamara;
Richards, Ryan

Publication type:

Article

The impact of misspecified covariate models on inclusion and omission bias when using fixed effects and full random effects models.

Published in:

Journal of Pharmacokinetics & Pharmacodynamics, 2025, v. 52, n. 2, p. 1, doi. 10.1007/s10928-025-09964-9

By:

Nyberg, Joakim;
Jonsson, E. Niclas

Publication type:

Article

Reliability of in vitro data for the mechanistic prediction of brain extracellular fluid pharmacokinetics of P-glycoprotein substrates in vivo; are we scaling correctly?

Published in:

Journal of Pharmacokinetics & Pharmacodynamics, 2025, v. 52, n. 2, p. 1, doi. 10.1007/s10928-025-09963-w

By:

van Valkengoed, Daan W.;
Hirasawa, Makoto;
Rottschäfer, Vivi;
de Lange, Elizabeth C. M.

Publication type:

Article