Works matching IS 1567567X AND DT 2025 AND VI 52 AND IP 1

Results: 16

Quantifying natural amyloid plaque accumulation in the continuum of Alzheimer’s disease using ADNI.

Published in:

Journal of Pharmacokinetics & Pharmacodynamics, 2025, v. 52, n. 1, p. 1, doi. 10.1007/s10928-024-09959-y

By:

Elhefnawy, Marwa E.;
Patson, Noel;
Mouksassi, Samer;
Pillai, Goonaseelan;
Shcherbinin, Sergey;
Chigutsa, Emmanuel;
Gueorguieva, Ivelina

Publication type:

Article

Stronger together: a cross-SIG perspective on improving drug development.

Published in:

Journal of Pharmacokinetics & Pharmacodynamics, 2025, v. 52, n. 1, p. 1, doi. 10.1007/s10928-024-09960-5

By:

Fostvedt, Luke;
Zhou, Jiawei;
Kondic, Anna G.;
Androulakis, Ioannis P.;
Zhang, Tongli;
Pryor, Meghan;
Zhuang, Luning;
Elassaiss-Schaap, Jeroen;
Chan, Phyllis;
Moore, Helen;
Avedissian, Sean N.;
Tigh, Jeremy;
Goteti, Kosalaram;
Thanneer, Neelima;
Su, Jing;
Ait-Oudhia, Sihem

Publication type:

Article

A physiologically-based quantitative systems pharmacology model for mechanistic understanding of the response to alogliptin and its application in patients with renal impairment.

Published in:

Journal of Pharmacokinetics & Pharmacodynamics, 2025, v. 52, n. 1, p. 1, doi. 10.1007/s10928-025-09961-y

By:

Shen, Chaozhuang;
Xie, Haitang;
Jiang, Xuehua;
Wang, Ling

Publication type:

Article

No QT interval prolongation effect of sepiapterin: a concentration-QTc analysis of pooled data from phase 1 and phase 3 studies in healthy volunteers and patients with phenylketonuria.

Published in:

Journal of Pharmacokinetics & Pharmacodynamics, 2025, v. 52, n. 1, p. 1, doi. 10.1007/s10928-024-09948-1

By:

Gao, Lan;
Hu, Yongjun;
Smith, Neil;
Uvarov, Artem;
Peyret, Thomas;
Gosselin, Nathalie H.;
Kong, Ronald

Publication type:

Article

Do P-glycoprotein-mediated drug-drug interactions at the blood-brain barrier impact morphine brain distribution?

Published in:

Journal of Pharmacokinetics & Pharmacodynamics, 2025, v. 52, n. 1, p. 1, doi. 10.1007/s10928-024-09957-0

By:

Gülave, Berfin;
Lesmana, Ariel;
de Lange, Elizabeth CM;
van Hasselt, JG Coen

Publication type:

Article

Application of model-informed drug development (MIDD) for dose selection in regulatory submissions for drug approval in Japan.

Published in:

Journal of Pharmacokinetics & Pharmacodynamics, 2025, v. 52, n. 1, p. 1, doi. 10.1007/s10928-024-09954-3

By:

Sasaki, Tomohiro;
Katsube, Takayuki;
Hayato, Seiichi;
Yamaguchi, Shingo;
Tanaka, Jun;
Yoshimatsu, Hiroki;
Nakanishi, Yushi;
Kitamura, Atsushi;
Watase, Hirotaka;
Suganami, Hideki;
Matsuoka, Nobushige;
Hasegawa, Chihiro

Publication type:

Article

QSP modeling of a transiently inactivating antibody-drug conjugate highlights benefit of short antibody half life.

Published in:

Journal of Pharmacokinetics & Pharmacodynamics, 2025, v. 52, n. 1, p. 1, doi. 10.1007/s10928-024-09956-1

By:

Khera, Eshita;
Dharmarajan, Lekshmi;
Hainzl, Dominik;
Engelhardt, Volker;
Vostiarova, Helena;
Davis, John;
Ebel, Nicolas;
Wuersch, Kuno;
Romanet, Vincent;
Sharaby, Sherif;
Kearns, Jeffrey D.

Publication type:

Article

Application of model-informed drug development (MIDD) for dose selection in regulatory submissions for drug approval in Japan.

Published in:

Journal of Pharmacokinetics & Pharmacodynamics, 2025, v. 52, n. 1, p. 1, doi. 10.1007/s10928-024-09954-3

By:

Sasaki, Tomohiro;
Katsube, Takayuki;
Hayato, Seiichi;
Yamaguchi, Shingo;
Tanaka, Jun;
Yoshimatsu, Hiroki;
Nakanishi, Yushi;
Kitamura, Atsushi;
Watase, Hirotaka;
Suganami, Hideki;
Matsuoka, Nobushige;
Hasegawa, Chihiro

Publication type:

Article

Novel endpoints based on tumor size ratio to support early clinical decision-making in oncology drug-development.

Published in:

Journal of Pharmacokinetics & Pharmacodynamics, 2025, v. 52, n. 1, p. 1, doi. 10.1007/s10928-024-09946-3

By:

Chakraborty, Shubhadeep;
Aggarwal, Kshitij;
Chowdhury, Marzana;
Hamada, Izumi;
Hu, Chuanpu;
Kondic, Anna;
Mishra, Kaushal;
Paulucci, David;
Tiwari, Ram;
Appanna, Kalyanee Viraswami;
Balan, Mariann Micsinai;
Kumar, Arun

Publication type:

Article

Model-informed approach to estimate treatment effect in placebo-controlled clinical trials using an artificial intelligence-based propensity weighting methodology to account for non-specific responses to treatment.

Published in:

Journal of Pharmacokinetics & Pharmacodynamics, 2025, v. 52, n. 1, p. 1, doi. 10.1007/s10928-024-09950-7

By:

Gomeni, Roberto;
Bressolle-Gomeni, F.

Publication type:

Article

Comparison of the power and type 1 error of total score models for drug effect detection in clinical trials.

Published in:

Journal of Pharmacokinetics & Pharmacodynamics, 2025, v. 52, n. 1, p. 1, doi. 10.1007/s10928-024-09949-0

By:

Haem, Elham;
Karlsson, Mats O.;
Ueckert, Sebastian

Publication type:

Article

A PopPBPK-RL approach for precision dosing of benazepril in renal impaired patients.

Published in:

Journal of Pharmacokinetics & Pharmacodynamics, 2025, v. 52, n. 1, p. 1, doi. 10.1007/s10928-024-09953-4

By:

Vigueras, Guillermo;
Muñoz-Gil, Lucía;
Reinisch, Valerie;
Pinto, Joana T.

Publication type:

Article

Translational pharmacokinetic and pharmacodynamic modelling of the anti-ADAMTS-5 NANOBODY<sup>®</sup> (M6495) using the neo-epitope ARGS as a biomarker.

Published in:

Journal of Pharmacokinetics & Pharmacodynamics, 2025, v. 52, n. 1, p. 1, doi. 10.1007/s10928-024-09958-z

By:

Pereira, Joao N.S.;
Ottevaere, Ingrid;
Serruys, Benedikte;
Guehring, Hans;
Ladel, Christoph;
Lindemann, Sven

Publication type:

Article

Multiorgan-on-a-chip for cancer drug pharmacokinetics-pharmacodynamics (PK-PD) modeling and simulations.

Published in:

Journal of Pharmacokinetics & Pharmacodynamics, 2025, v. 52, n. 1, p. 1, doi. 10.1007/s10928-024-09955-2

By:

Mohammed, Abdurehman Eshete;
Kurucaovalı, Filiz;
Okvur, Devrim Pesen

Publication type:

Article

Translational population target binding model for the anti-FcRn fragment antibody efgartigimod.

Published in:

Journal of Pharmacokinetics & Pharmacodynamics, 2025, v. 52, n. 1, p. 1, doi. 10.1007/s10928-024-09952-5

By:

Hoefman, Sven;
van Steeg, Tamara;
Ottevaere, Ingrid;
Baumeister, Judith;
Rossenu, Stefaan

Publication type:

Article

Semi-mechanistic population pharmacokinetic modeling of DZIF-10c, a neutralizing antibody against SARS-Cov-2: predicting systemic and lung exposure following inhaled and intravenous administration.

Published in:

Journal of Pharmacokinetics & Pharmacodynamics, 2025, v. 52, n. 1, p. 1, doi. 10.1007/s10928-024-09947-2

By:

Kurup, Sree;
de Mendizabal, Nieves Velez;
Becker, Stephan;
Bolella, Erica;
De Sousa, Dorothy;
Fätkenheuer, Gerd;
Gruell, Henning;
Klein, Florian;
Malin, Jakob J;
Schmid, Ulrike;
Korell, Julia

Publication type:

Article