Works matching IS 15537390 AND DT 2024 AND VI 20 AND IP 12

Results: 32

Fitness landscapes of human microsatellites.

Published in:

PLoS Genetics, 2024, v. 20, n. 12, p. 1, doi. 10.1371/journal.pgen.1011524

By:

Haasl, Ryan J.;
Payseur, Bret A.

Publication type:

Article

Estimating the proportion of beneficial mutations that are not adaptive in mammals.

Published in:

PLoS Genetics, 2024, v. 20, n. 12, p. 1, doi. 10.1371/journal.pgen.1011536

By:

Latrille, Thibault;
Joseph, Julien;
Hartasánchez, Diego A.;
Salamin, Nicolas

Publication type:

Article

Decreased Hsp90 activity protects against TDP-43 neurotoxicity in a C. elegans model of amyotrophic lateral sclerosis.

Published in:

PLoS Genetics, 2024, v. 20, n. 12, p. 1, doi. 10.1371/journal.pgen.1011518

By:

Garcia-Toscano, Laura;
Currey, Heather N.;
Hincks, Joshua C.;
Stair, Jade G.;
Lehrbach, Nicolas J.;
Liachko, Nicole F.

Publication type:

Article

Inhibitory KIRs decrease HLA class II-mediated protection in Type 1 Diabetes.

Published in:

PLoS Genetics, 2024, v. 20, n. 12, p. 1, doi. 10.1371/journal.pgen.1011456

By:

Mora-Bitria, Laura;
Debebe, Bisrat J.;
Miners, Kelly L.;
Ladell, Kristin;
Kaur, Charandeep;
Traherne, James A.;
Jiang, Wei;
Price, David A.;
Hadcocks, Linda;
McQuibban, Nicholas A. R.;
Trowsdale, John;
Wong, F Susan;
Pontikos, Nikolas;
Niederalt, Christoph;
Asquith, Becca

Publication type:

Article

RcsF-independent mechanisms of signaling within the Rcs phosphorelay.

Published in:

PLoS Genetics, 2024, v. 20, n. 12, p. 1, doi. 10.1371/journal.pgen.1011408

By:

Petchiappan, Anushya;
Majdalani, Nadim;
Wall, Erin;
Gottesman, Susan

Publication type:

Article

Polyploids broadly generate novel haplotypes from trans-specific variation in Arabidopsis arenosa and Arabidopsis lyrata.

Published in:

PLoS Genetics, 2024, v. 20, n. 12, p. 1, doi. 10.1371/journal.pgen.1011521

By:

Bohutínská, Magdalena;
Petříková, Eliška;
Booker, Tom R.;
Vives Cobo, Cristina;
Vlček, Jakub;
Šrámková, Gabriela;
Poupětová, Alžběta;
Hojka, Jakub;
Marhold, Karol;
Yant, Levi;
Kolář, Filip;
Schmickl, Roswitha

Publication type:

Article

Runx3, Brn3a and Isl1 interplay orchestrates the transcriptional program in the early stages of proprioceptive neuron development.

Published in:

PLoS Genetics, 2024, v. 20, n. 12, p. 1, doi. 10.1371/journal.pgen.1011401

By:

Orlovsky, Kira;
Appel, Elena;
Hantisteanu, Shay;
Olender, Tsviya;
Lotem, Joseph;
Levanon, Ditsa;
Groner, Yoram

Publication type:

Article

Non-autonomous insulin signaling delays mitotic progression in C. elegans germline stem and progenitor cells.

Published in:

PLoS Genetics, 2024, v. 20, n. 12, p. 1, doi. 10.1371/journal.pgen.1011351

By:

Cheng, Eric;
Lu, Ran;
Gerhold, Abigail R.

Publication type:

Article

Multiple independent genetic code reassignments of the UAG stop codon in phyllopharyngean ciliates.

Published in:

PLoS Genetics, 2024, v. 20, n. 12, p. 1, doi. 10.1371/journal.pgen.1011512

By:

McGowan, Jamie;
Richards, Thomas A.;
Hall, Neil;
Swarbreck, David

Publication type:

Article

A Taybi-Linder syndrome-related RTTN variant impedes neural rosette formation in human cortical organoids.

Published in:

PLoS Genetics, 2024, v. 20, n. 12, p. 1, doi. 10.1371/journal.pgen.1011517

By:

Guguin, Justine;
Chen, Ting-Yu;
Cuinat, Silvestre;
Besson, Alicia;
Bertiaux, Eloïse;
Boutaud, Lucile;
Ardito, Nolan;
Imaz Murguiondo, Miren;
Cabet, Sara;
Hamel, Virginie;
Thomas, Sophie;
Pain, Bertrand;
Edery, Patrick;
Putoux, Audrey;
Tang, Tang K.;
Mazoyer, Sylvie;
Delous, Marion

Publication type:

Article

Spop deficiency impairs adipogenesis and promotes thermogenic capacity in mice.

Published in:

PLoS Genetics, 2024, v. 20, n. 12, p. 1, doi. 10.1371/journal.pgen.1011514

By:

Li, Qinghe;
Liu, Yuhong;
Wang, Yuanyuan;
Zhang, Qi;
Zhang, Na;
Song, Danli;
Wang, Fei;
Gao, Qianmei;
Chen, Yuxin;
Zhang, Gaomeng;
Wen, Jie;
Zhao, Guiping;
Chen, Li;
Gao, Yu

Publication type:

Article

Estimating and visualising multivariable Mendelian randomization analyses within a radial framework.

Published in:

PLoS Genetics, 2024, v. 20, n. 12, p. 1, doi. 10.1371/journal.pgen.1011506

By:

Spiller, Wes;
Bowden, Jack;
Sanderson, Eleanor

Publication type:

Article

Adjusting for principal components can induce collider bias in genome-wide association studies.

Published in:

PLoS Genetics, 2024, v. 20, n. 12, p. 1, doi. 10.1371/journal.pgen.1011242

By:

Grinde, Kelsey E.;
Browning, Brian L.;
Reiner, Alexander P.;
Thornton, Timothy A.;
Browning, Sharon R.

Publication type:

Article

The cells are all-right: Regulation of the Lefty genes by separate enhancers in mouse embryonic stem cells.

Published in:

PLoS Genetics, 2024, v. 20, n. 12, p. 1, doi. 10.1371/journal.pgen.1011513

By:

Taylor, Tiegh;
Zhu, Hongyu Vicky;
Moorthy, Sakthi D.;
Khader, Nawrah;
Mitchell, Jennifer A.

Publication type:

Article

Integrin adhesome axis inhibits the RPM-1 ubiquitin ligase signaling hub to regulate growth cone and axon development.

Published in:

PLoS Genetics, 2024, v. 20, n. 12, p. 1, doi. 10.1371/journal.pgen.1011496

By:

Amezquita, Jonathan;
Desbois, Muriel;
Opperman, Karla J.;
Pak, Joseph S.;
Christensen, Elyse L.;
Nguyen, Nikki T.;
Diaz-Garcia, Karen;
Borgen, Melissa A.;
Grill, Brock

Publication type:

Article

TransferGWAS of T1-weighted brain MRI data from UK Biobank.

Published in:

PLoS Genetics, 2024, v. 20, n. 12, p. 1, doi. 10.1371/journal.pgen.1011332

By:

Rakowski, Alexander;
Monti, Remo;
Lippert, Christoph

Publication type:

Article

The Tumor-Associated Calcium Signal Transducer 2 (TACSTD2) oncogene is upregulated in cystic epithelial cells revealing a potential new target for polycystic kidney disease.

Published in:

PLoS Genetics, 2024, v. 20, n. 12, p. 1, doi. 10.1371/journal.pgen.1011510

By:

Smith, Abigail O.;
Frantz, William Tyler;
Preval, Kenley M.;
Edwards, Yvonne J. K.;
Ceol, Craig J.;
Jonassen, Julie A.;
Pazour, Gregory J.

Publication type:

Article

Loss of Notch dimerization perturbs intestinal homeostasis by a mechanism involving HDAC activity.

Published in:

PLoS Genetics, 2024, v. 20, n. 12, p. 1, doi. 10.1371/journal.pgen.1011486

By:

Dai, Quanhui;
Preusse, Kristina;
Yu, Danni;
Kovall, Rhett A.;
Thorner, Konrad;
Lin, Xinhua;
Kopan, Raphael

Publication type:

Article

Ustilago maydis Trf2 ensures genome stability by antagonizing Blm-mediated telomere recombination: Fine-tuning DNA repair factor activity at telomeres through opposing regulations.

Published in:

PLoS Genetics, 2024, v. 20, n. 12, p. 1, doi. 10.1371/journal.pgen.1011515

By:

Syed, Shahrez;
Aloe, Sarah;
Sutherland, Jeanette H.;
Holloman, William K.;
Lue, Neal F.

Publication type:

Article

Cbf11 and Mga2 function together to activate transcription of lipid metabolism genes and promote mitotic fidelity in fission yeast.

Published in:

PLoS Genetics, 2024, v. 20, n. 12, p. 1, doi. 10.1371/journal.pgen.1011509

By:

Marešová, Anna;
Grulyová, Michaela;
Hradilová, Miluše;
Zemlianski, Viacheslav;
Princová, Jarmila;
Převorovský, Martin

Publication type:

Article

Hsp90 and cochaperones have two genetically distinct roles in regulating eEF2 function.

Published in:

PLoS Genetics, 2024, v. 20, n. 12, p. 1, doi. 10.1371/journal.pgen.1011508

By:

Fulton, Melody D.;
Yama, Danielle J.;
Dahl, Ella;
Johnson, Jill L.

Publication type:

Article

Separable roles of the DNA damage response kinase Mec1ATR and its activator Rad24RAD17 during meiotic recombination.

Published in:

PLoS Genetics, 2024, v. 20, n. 12, p. 1, doi. 10.1371/journal.pgen.1011485

By:

Crawford, Margaret R.;
Harper, Jon A.;
Cooper, Tim J.;
Marsolier-Kergoat, Marie-Claude;
Llorente, Bertrand;
Neale, Matthew J.

Publication type:

Article

Cell-free placental DNA: What do we really know?

Published in:

PLoS Genetics, 2024, v. 20, n. 12, p. 1, doi. 10.1371/journal.pgen.1011484

By:

Yuen, Natalie;
Lemaire, Melanie;
Wilson, Samantha L.

Publication type:

Article

Transcription termination and antitermination are critical for the fitness and function of the integrative and conjugative element Tn916.

Published in:

PLoS Genetics, 2024, v. 20, n. 12, p. 1, doi. 10.1371/journal.pgen.1011417

By:

Wirachman, Erika S.;
Grossman, Alan D.

Publication type:

Article

Acetylation of the yeast Hsp40 chaperone protein Ydj1 fine-tunes proteostasis and translational fidelity.

Published in:

PLoS Genetics, 2024, v. 20, n. 12, p. 1, doi. 10.1371/journal.pgen.1011338

By:

Omkar, Siddhi;
Mitchem, Megan M.;
Hoskins, Joel R.;
Shrader, Courtney;
Kline, Jake T.;
Nitika;
Fornelli, Luca;
Wickner, Sue;
Truman, Andrew W.

Publication type:

Article

Functional investigation suggests CNTNAP5 involvement in glaucomatous neurodegeneration obtained from a GWAS in primary angle closure glaucoma.

Published in:

PLoS Genetics, 2024, v. 20, n. 12, p. 1, doi. 10.1371/journal.pgen.1011502

By:

Chakraborty, Sudipta;
Sarma, Jyotishman;
Roy, Shantanu Saha;
Mitra, Sukanya;
Bagchi, Sayani;
Das, Sankhadip;
Saha, Sreemoyee;
Mahapatra, Surajit;
Bhattacharjee, Samsiddhi;
Maulik, Mahua;
Acharya, Moulinath

Publication type:

Article

Cysteine Rich Intestinal Protein 2 is a copper-responsive regulator of skeletal muscle differentiation and metal homeostasis.

Published in:

PLoS Genetics, 2024, v. 20, n. 12, p. 1, doi. 10.1371/journal.pgen.1011495

By:

Verdejo-Torres, Odette;
Klein, David C.;
Novoa-Aponte, Lorena;
Carrazco-Carrillo, Jaime;
Bonilla-Pinto, Denzel;
Rivera, Antonio;
Bakhshian, Arpie;
Fitisemanu, Fa'alataitaua M.;
Jiménez-González, Martha L.;
Flinn, Lyra;
Pezacki, Aidan T.;
Lanzirotti, Antonio;
Ortiz Frade, Luis Antonio;
Chang, Christopher J.;
Navea, Juan G.;
Blaby-Haas, Crysten E.;
Hainer, Sarah J.;
Padilla-Benavides, Teresita

Publication type:

Article

Disentangling the consequences of type 2 diabetes on targeted metabolite profiles using causal inference and interaction QTL analyses.

Published in:

PLoS Genetics, 2024, v. 20, n. 12, p. 1, doi. 10.1371/journal.pgen.1011346

By:

Bocher, Ozvan;
Singh, Archit;
Huang, Yue;
Võsa, Urmo;
Reimann, Ene;
Arruda, Ana;
Barysenska, Andrei;
Kolde, Anastassia;
Rayner, Nigel W.;
Esko, Tõnu;
Mägi, Reedik;
Zeggini, Eleftheria

Publication type:

Article

FABIO: TWAS fine-mapping to prioritize causal genes for binary traits.

Published in:

PLoS Genetics, 2024, v. 20, n. 12, p. 1, doi. 10.1371/journal.pgen.1011503

By:

Zhang, Haihan;
He, Kevin;
Li, Zheng;
Tsoi, Lam C.;
Zhou, Xiang

Publication type:

Article

The RNA-dependent association of phosphatidylinositol 4,5-bisphosphate with intrinsically disordered proteins contribute to nuclear compartmentalization.

Published in:

PLoS Genetics, 2024, v. 20, n. 12, p. 1, doi. 10.1371/journal.pgen.1011462

By:

Sztacho, Martin;
Červenka, Jakub;
Šalovská, Barbora;
Antiga, Ludovica;
Hoboth, Peter;
Hozák, Pavel

Publication type:

Article

Different germline variants in the XPA gene are associated with severe, intermediate, or mild neurodegeneration in xeroderma pigmentosum patients.

Published in:

PLoS Genetics, 2024, v. 20, n. 12, p. 1, doi. 10.1371/journal.pgen.1011265

By:

Sagun, Jeffrey P.;
Khan, Sikandar G.;
Imoto, Kyoko;
Tamura, Deborah;
Oh, Kyu-Seon;
DiGiovanna, John J.;
Kraemer, Kenneth H.

Publication type:

Article

FST and genetic diversity in an island model with background selection.

Published in:

PLoS Genetics, 2024, v. 20, n. 12, p. 1, doi. 10.1371/journal.pgen.1011225

By:

Hasan, Asad;
Whitlock, Michael C.

Publication type:

Article

Works matching IS 15537390 AND DT 2024 AND VI 20 AND IP 12

Fitness landscapes of human microsatellites.

Estimating the proportion of beneficial mutations that are not adaptive in mammals.

Decreased Hsp90 activity protects against TDP-43 neurotoxicity in a C. elegans model of amyotrophic lateral sclerosis.

Inhibitory KIRs decrease HLA class II-mediated protection in Type 1 Diabetes.

RcsF-independent mechanisms of signaling within the Rcs phosphorelay.

Polyploids broadly generate novel haplotypes from trans-specific variation in Arabidopsis arenosa and Arabidopsis lyrata.

Runx3, Brn3a and Isl1 interplay orchestrates the transcriptional program in the early stages of proprioceptive neuron development.

Non-autonomous insulin signaling delays mitotic progression in C. elegans germline stem and progenitor cells.

Multiple independent genetic code reassignments of the UAG stop codon in phyllopharyngean ciliates.

A Taybi-Linder syndrome-related RTTN variant impedes neural rosette formation in human cortical organoids.

Spop deficiency impairs adipogenesis and promotes thermogenic capacity in mice.

Estimating and visualising multivariable Mendelian randomization analyses within a radial framework.

Adjusting for principal components can induce collider bias in genome-wide association studies.

The cells are all-right: Regulation of the Lefty genes by separate enhancers in mouse embryonic stem cells.

Integrin adhesome axis inhibits the RPM-1 ubiquitin ligase signaling hub to regulate growth cone and axon development.

TransferGWAS of T1-weighted brain MRI data from UK Biobank.

The Tumor-Associated Calcium Signal Transducer 2 (TACSTD2) oncogene is upregulated in cystic epithelial cells revealing a potential new target for polycystic kidney disease.

Loss of Notch dimerization perturbs intestinal homeostasis by a mechanism involving HDAC activity.

Ustilago maydis Trf2 ensures genome stability by antagonizing Blm-mediated telomere recombination: Fine-tuning DNA repair factor activity at telomeres through opposing regulations.

Cbf11 and Mga2 function together to activate transcription of lipid metabolism genes and promote mitotic fidelity in fission yeast.

Hsp90 and cochaperones have two genetically distinct roles in regulating eEF2 function.

Separable roles of the DNA damage response kinase Mec1<sup>ATR</sup> and its activator Rad24<sup>RAD17</sup> during meiotic recombination.

Cell-free placental DNA: What do we really know?

Transcription termination and antitermination are critical for the fitness and function of the integrative and conjugative element Tn916.

Acetylation of the yeast Hsp40 chaperone protein Ydj1 fine-tunes proteostasis and translational fidelity.

Functional investigation suggests CNTNAP5 involvement in glaucomatous neurodegeneration obtained from a GWAS in primary angle closure glaucoma.

Cysteine Rich Intestinal Protein 2 is a copper-responsive regulator of skeletal muscle differentiation and metal homeostasis.

Disentangling the consequences of type 2 diabetes on targeted metabolite profiles using causal inference and interaction QTL analyses.

FABIO: TWAS fine-mapping to prioritize causal genes for binary traits.

The RNA-dependent association of phosphatidylinositol 4,5-bisphosphate with intrinsically disordered proteins contribute to nuclear compartmentalization.

Different germline variants in the XPA gene are associated with severe, intermediate, or mild neurodegeneration in xeroderma pigmentosum patients.

F<sub>ST</sub> and genetic diversity in an island model with background selection.