Works matching IS 1553734X AND DT 2020

Results: 773

Simple models including energy and spike constraints reproduce complex activity patterns and metabolic disruptions.

Published in:

PLoS Computational Biology, 2020, v. 16, n. 12, p. 1, doi. 10.1371/journal.pcbi.1008503

By:

Fardet, Tanguy;
Levina, Anna

Publication type:

Article

Estimating individuals' genetic and non-genetic effects underlying infectious disease transmission from temporal epidemic data.

Published in:

PLoS Computational Biology, 2020, v. 16, n. 12, p. 1, doi. 10.1371/journal.pcbi.1008447

By:

Pooley, Christopher M.;
Marion, Glenn;
Bishop, Stephen C.;
Bailey, Richard I.;
Doeschl-Wilson, Andrea B.

Publication type:

Article

Crosstalk and ultrasensitivity in protein degradation pathways.

Published in:

PLoS Computational Biology, 2020, v. 16, n. 12, p. 1, doi. 10.1371/journal.pcbi.1008492

By:

Mallela, Abhishek;
Nariya, Maulik K.;
Deeds, Eric J.

Publication type:

Article

On the NF-Y regulome as in ENCODE (2019).

Published in:

PLoS Computational Biology, 2020, v. 16, n. 12, p. 1, doi. 10.1371/journal.pcbi.1008488

By:

Ronzio, Mirko;
Bernardini, Andrea;
Pavesi, Giulio;
Mantovani, Roberto;
Dolfini, Diletta

Publication type:

Article

Optimal adjustment of the human circadian clock in the real world.

Published in:

PLoS Computational Biology, 2020, v. 16, n. 12, p. 1, doi. 10.1371/journal.pcbi.1008445

By:

Christensen, Samuel;
Huang, Yitong;
Walch, Olivia J.;
Forger, Daniel B.

Publication type:

Article

A novel virtual screening procedure identifies Pralatrexate as inhibitor of SARS-CoV-2 RdRp and it reduces viral replication in vitro.

Published in:

PLoS Computational Biology, 2020, v. 16, n. 12, p. 1, doi. 10.1371/journal.pcbi.1008489

By:

Zhang, Haiping;
Yang, Yang;
Li, Junxin;
Wang, Min;
Saravanan, Konda Mani;
Wei, Jinli;
Tze-Yang Ng, Justin;
Tofazzal Hossain, Md.;
Liu, Maoxuan;
Zhang, Huiling;
Ren, Xiaohu;
Pan, Yi;
Peng, Yin;
Shi, Yi;
Wan, Xiaochun;
Liu, Yingxia;
Wei, Yanjie

Publication type:

Article

Ten quick tips for making things findable.

Published in:

PLoS Computational Biology, 2020, v. 16, n. 12, p. 1, doi. 10.1371/journal.pcbi.1008469

By:

Lin, Sarah;
Ali, Ibraheem;
Wilson, Greg

Publication type:

Article

Ten simple rules for typographically appealing scientific texts.

Published in:

PLoS Computational Biology, 2020, v. 16, n. 12, p. 1, doi. 10.1371/journal.pcbi.1008458

By:

Schwen, Lars Ole

Publication type:

Article

PremPS: Predicting the impact of missense mutations on protein stability.

Published in:

PLoS Computational Biology, 2020, v. 16, n. 12, p. 1, doi. 10.1371/journal.pcbi.1008543

By:

Chen, Yuting;
Lu, Haoyu;
Zhang, Ning;
Zhu, Zefeng;
Wang, Shuqin;
Li, Minghui

Publication type:

Article

NGS-PrimerPlex: High-throughput primer design for multiplex polymerase chain reactions.

Published in:

PLoS Computational Biology, 2020, v. 16, n. 12, p. 1, doi. 10.1371/journal.pcbi.1008468

By:

Kechin, Andrey;
Borobova, Viktoria;
Boyarskikh, Ulyana;
Khrapov, Evgeniy;
Subbotin, Sergey;
Filipenko, Maxim

Publication type:

Article

Cerebellar Golgi cell models predict dendritic processing and mechanisms of synaptic plasticity.

Published in:

PLoS Computational Biology, 2020, v. 16, n. 12, p. 1, doi. 10.1371/journal.pcbi.1007937

By:

Masoli, Stefano;
Ottaviani, Alessandra;
Casali, Stefano;
D'Angelo, Egidio

Publication type:

Article

Modeling habitat connectivity in support of multiobjective species movement: An application to amphibian habitat systems.

Published in:

PLoS Computational Biology, 2020, v. 16, n. 12, p. 1, doi. 10.1371/journal.pcbi.1008540

By:

Matisziw, Timothy C.;
Gholamialam, Ashkan;
Trauth, Kathleen M.

Publication type:

Article

Multiobjective optimization identifies cancer-selective combination therapies.

Published in:

PLoS Computational Biology, 2020, v. 16, n. 12, p. 1, doi. 10.1371/journal.pcbi.1008538

By:

Pulkkinen, Otto I.;
Gautam, Prson;
Mustonen, Ville;
Aittokallio, Tero

Publication type:

Article

Optimal learning with excitatory and inhibitory synapses.

Published in:

PLoS Computational Biology, 2020, v. 16, n. 12, p. 1, doi. 10.1371/journal.pcbi.1008536

By:

Ingrosso, Alessandro

Publication type:

Article

Measuring spectrally-resolved information transfer.

Published in:

PLoS Computational Biology, 2020, v. 16, n. 12, p. 1, doi. 10.1371/journal.pcbi.1008526

By:

Pinzuti, Edoardo;
Wollstadt, Patricia;
Gutknecht, Aaron;
Tüscher, Oliver;
Wibral, Michael

Publication type:

Article

Systems biology predicts that fibrosis in tuberculous granulomas may arise through macrophage-to-myofibroblast transformation.

Published in:

PLoS Computational Biology, 2020, v. 16, n. 12, p. 1, doi. 10.1371/journal.pcbi.1008520

By:

Evans, Stephanie;
Butler, J. Russell;
Mattila, Joshua T.;
Kirschner, Denise E.

Publication type:

Article

OpenSim Moco: Musculoskeletal optimal control.

Published in:

PLoS Computational Biology, 2020, v. 16, n. 12, p. 1, doi. 10.1371/journal.pcbi.1008493

By:

Dembia, Christopher L.;
Bianco, Nicholas A.;
Falisse, Antoine;
Hicks, Jennifer L.;
Delp, Scott L.

Publication type:

Article

A modular framework for multiscale, multicellular, spatiotemporal modeling of acute primary viral infection and immune response in epithelial tissues and its application to drug therapy timing and effectiveness.

Published in:

PLoS Computational Biology, 2020, v. 16, n. 12, p. 1, doi. 10.1371/journal.pcbi.1008451

By:

Sego, T. J.;
Aponte-Serrano, Josua O.;
Ferrari Gianlupi, Juliano;
Heaps, Samuel R.;
Breithaupt, Kira;
Brusch, Lutz;
Crawshaw, Jessica;
Osborne, James M.;
Quardokus, Ellen M.;
Plemper, Richard K.;
Glazier, James A.

Publication type:

Article

The COVID-19 outbreak in Sichuan, China: Epidemiology and impact of interventions.

Published in:

PLoS Computational Biology, 2020, v. 16, n. 12, p. 1, doi. 10.1371/journal.pcbi.1008467

By:

Liu, Quan-Hui;
Bento, Ana I.;
Yang, Kexin;
Zhang, Hang;
Yang, Xiaohan;
Merler, Stefano;
Vespignani, Alessandro;
Lv, Jiancheng;
Yu, Hongjie;
Zhang, Wei;
Zhou, Tao;
Ajelli, Marco

Publication type:

Article

Confidence intervals by constrained optimization—An algorithm and software package for practical identifiability analysis in systems biology.

Published in:

PLoS Computational Biology, 2020, v. 16, n. 12, p. 1, doi. 10.1371/journal.pcbi.1008495

By:

Borisov, Ivan;
Metelkin, Evgeny

Publication type:

Article

Evaluation of CD8 T cell killing models with computer simulations of 2-photon imaging experiments.

Published in:

PLoS Computational Biology, 2020, v. 16, n. 12, p. 1, doi. 10.1371/journal.pcbi.1008428

By:

Rastogi, Ananya;
Robert, Philippe A.;
Halle, Stephan;
Meyer-Hermann, Michael

Publication type:

Article

Predictive network modeling in human induced pluripotent stem cells identifies key driver genes for insulin responsiveness.

Published in:

PLoS Computational Biology, 2020, v. 16, n. 12, p. 1, doi. 10.1371/journal.pcbi.1008491

By:

Carcamo-Orive, Ivan;
Henrion, Marc Y. R.;
Zhu, Kuixi;
Beckmann, Noam D.;
Cundiff, Paige;
Moein, Sara;
Zhang, Zenan;
Alamprese, Melissa;
D'Souza, Sunita L.;
Wabitsch, Martin;
Schadt, Eric E.;
Quertermous, Thomas;
Knowles, Joshua W.;
Chang, Rui

Publication type:

Article

Multi-scale modeling of macrophage—T cell interactions within the tumor microenvironment.

Published in:

PLoS Computational Biology, 2020, v. 16, n. 12, p. 1, doi. 10.1371/journal.pcbi.1008519

By:

Cess, Colin G.;
Finley, Stacey D.

Publication type:

Article

Unbiased and efficient log-likelihood estimation with inverse binomial sampling.

Published in:

PLoS Computational Biology, 2020, v. 16, n. 12, p. 1, doi. 10.1371/journal.pcbi.1008483

By:

van Opheusden, Bas;
Acerbi, Luigi;
Ma, Wei Ji

Publication type:

Article

Practical fluorescence reconstruction microscopy for large samples and low-magnification imaging.

Published in:

PLoS Computational Biology, 2020, v. 16, n. 12, p. 1, doi. 10.1371/journal.pcbi.1008443

By:

LaChance, Julienne;
Cohen, Daniel J.

Publication type:

Article

Tracking collective cell motion by topological data analysis.

Published in:

PLoS Computational Biology, 2020, v. 16, n. 12, p. 1, doi. 10.1371/journal.pcbi.1008407

By:

Bonilla, Luis L.;
Carpio, Ana;
Trenado, Carolina

Publication type:

Article

A functional theory of bistable perception based on dynamical circular inference.

Published in:

PLoS Computational Biology, 2020, v. 16, n. 12, p. 1, doi. 10.1371/journal.pcbi.1008480

By:

Leptourgos, Pantelis;
Bouttier, Vincent;
Jardri, Renaud;
Denève, Sophie

Publication type:

Article

Classification and phylogeny for the annotation of novel eukaryotic GNAT acetyltransferases.

Published in:

PLoS Computational Biology, 2020, v. 16, n. 12, p. 1, doi. 10.1371/journal.pcbi.1007988

By:

Krtenic, Bojan;
Drazic, Adrian;
Arnesen, Thomas;
Reuter, Nathalie

Publication type:

Article

CHOmics: A web-based tool for multi-omics data analysis and interactive visualization in CHO cell lines.

Published in:

PLoS Computational Biology, 2020, v. 16, n. 12, p. 1, doi. 10.1371/journal.pcbi.1008498

By:

Lin, Dongdong;
Yalamanchili, Hima B.;
Zhang, Xinmin;
Lewis, Nathan E.;
Alves, Christina S.;
Groot, Joost;
Arnsdorf, Johnny;
Bjørn, Sara P.;
Wulff, Tune;
Voldborg, Bjørn G.;
Zhou, Yizhou;
Zhang, Baohong

Publication type:

Article

IOCBIO Kinetics: An open-source software solution for analysis of data traces.

Published in:

PLoS Computational Biology, 2020, v. 16, n. 12, p. 1, doi. 10.1371/journal.pcbi.1008475

By:

Vendelin, Marko;
Laasmaa, Martin;
Kalda, Mari;
Branovets, Jelena;
Karro, Niina;
Barsunova, Karina;
Birkedal, Rikke

Publication type:

Article

Robust detection of point mutations involved in multidrug-resistant Mycobacterium tuberculosis in the presence of co-occurrent resistance markers.

Published in:

PLoS Computational Biology, 2020, v. 16, n. 12, p. 1, doi. 10.1371/journal.pcbi.1008518

By:

Libiseller-Egger, Julian;
Phelan, Jody;
Campino, Susana;
Mohareb, Fady;
Clark, Taane G.

Publication type:

Article

Reconciling emergences: An information-theoretic approach to identify causal emergence in multivariate data.

Published in:

PLoS Computational Biology, 2020, v. 16, n. 12, p. 1, doi. 10.1371/journal.pcbi.1008289

By:

Rosas, Fernando E.;
Mediano, Pedro A. M.;
Jensen, Henrik J.;
Seth, Anil K.;
Barrett, Adam B.;
Carhart-Harris, Robin L.;
Bor, Daniel

Publication type:

Article

Differential effects of propofol and ketamine on critical brain dynamics.

Published in:

PLoS Computational Biology, 2020, v. 16, n. 12, p. 1, doi. 10.1371/journal.pcbi.1008418

By:

Varley, Thomas F.;
Sporns, Olaf;
Puce, Aina;
Beggs, John

Publication type:

Article

Synaptic polarity and sign-balance prediction using gene expression data in the Caenorhabditis elegans chemical synapse neuronal connectome network.

Published in:

PLoS Computational Biology, 2020, v. 16, n. 12, p. 1, doi. 10.1371/journal.pcbi.1007974

By:

Fenyves, Bánk G.;
Szilágyi, Gábor S.;
Vassy, Zsolt;
Sőti, Csaba;
Csermely, Peter

Publication type:

Article

A joint modeling approach for longitudinal microbiome data improves ability to detect microbiome associations with disease.

Published in:

PLoS Computational Biology, 2020, v. 16, n. 12, p. 1, doi. 10.1371/journal.pcbi.1008473

By:

Luna, Pamela N.;
Mansbach, Jonathan M.;
Shaw, Chad A.

Publication type:

Article

Mapping molar shapes on signaling pathways.

Published in:

PLoS Computational Biology, 2020, v. 16, n. 12, p. 1, doi. 10.1371/journal.pcbi.1008436

By:

Morita, Wataru;
Morimoto, Naoki;
Jernvall, Jukka

Publication type:

Article

Phenotypes to remember: Evolutionary developmental memory capacity and robustness.

Published in:

PLoS Computational Biology, 2020, v. 16, n. 11, p. 1, doi. 10.1371/journal.pcbi.1008425

By:

Szilágyi, András;
Szabó, Péter;
Santos, Mauro;
Szathmáry, Eörs

Publication type:

Article

Context-specific network modeling identifies new crosstalk in β-adrenergic cardiac hypertrophy.

Published in:

PLoS Computational Biology, 2020, v. 16, n. 12, p. 1, doi. 10.1371/journal.pcbi.1008490

By:

Khalilimeybodi, Ali;
Paap, Alexander M.;
Christiansen, Steven L. M.;
Saucerman, Jeffrey J.

Publication type:

Article

Ten simple rules for creating a brand-new virtual academic meeting (even amid a pandemic).

Published in:

2020

By:

Rich, Scott;
Diaconescu, Andreea O.;
Griffiths, John D.;
Lankarany, Milad

Publication type:

Editorial

Development of a hybrid model for a partially known intracellular signaling pathway through correction term estimation and neural network modeling.

Published in:

PLoS Computational Biology, 2020, v. 16, n. 12, p. 1, doi. 10.1371/journal.pcbi.1008472

By:

Lee, Dongheon;
Jayaraman, Arul;
Kwon, Joseph S.

Publication type:

Article

A mechanistic model of the BLADE platform predicts performance characteristics of 256 different synthetic DNA recombination circuits.

Published in:

PLoS Computational Biology, 2020, v. 16, n. 12, p. 1, doi. 10.1371/journal.pcbi.1007849

By:

Bowyer, Jack E.;
Ding, Chloe;
Weinberg, Benjamin H.;
Wong, Wilson W.;
Bates, Declan G.

Publication type:

Article

Hi-C implementation of genome structure for in silico models of radiation-induced DNA damage.

Published in:

PLoS Computational Biology, 2020, v. 16, n. 12, p. 1, doi. 10.1371/journal.pcbi.1008476

By:

Ingram, Samuel P.;
Henthorn, Nicholas T.;
Warmenhoven, John W.;
Kirkby, Norman F.;
Mackay, Ranald I.;
Kirkby, Karen J.;
Merchant, Michael J.

Publication type:

Article

Approximating complex musculoskeletal biomechanics using multidimensional autogenerating polynomials.

Published in:

PLoS Computational Biology, 2020, v. 16, n. 12, p. 1, doi. 10.1371/journal.pcbi.1008350

By:

Sobinov, Anton;
Boots, Matthew T.;
Gritsenko, Valeriya;
Fisher, Lee E.;
Gaunt, Robert A.;
Yakovenko, Sergiy

Publication type:

Article

Exact neural mass model for synaptic-based working memory.

Published in:

PLoS Computational Biology, 2020, v. 16, n. 12, p. 1, doi. 10.1371/journal.pcbi.1008533

By:

Taher, Halgurd;
Torcini, Alessandro;
Olmi, Simona

Publication type:

Article

A mechanistic framework for a priori pharmacokinetic predictions of orally inhaled drugs.

Published in:

PLoS Computational Biology, 2020, v. 16, n. 12, p. 1, doi. 10.1371/journal.pcbi.1008466

By:

Hartung, Niklas;
Borghardt, Jens Markus

Publication type:

Article

Defect patterns on the curved surface of fish retinae suggest a mechanism of cone mosaic formation.

Published in:

PLoS Computational Biology, 2020, v. 16, n. 12, p. 1, doi. 10.1371/journal.pcbi.1008437

By:

Nunley, Hayden;
Nagashima, Mikiko;
Martin, Kamirah;
Lorenzo Gonzalez, Alcides;
Suzuki, Sachihiro C.;
Norton, Declan A.;
Wong, Rachel O. L.;
Raymond, Pamela A.;
Lubensky, David K.

Publication type:

Article

A Bayesian computational model reveals a failure to adapt interoceptive precision estimates across depression, anxiety, eating, and substance use disorders.

Published in:

PLoS Computational Biology, 2020, v. 16, n. 12, p. 1, doi. 10.1371/journal.pcbi.1008484

By:

Smith, Ryan;
Kuplicki, Rayus;
Feinstein, Justin;
Forthman, Katherine L.;
Stewart, Jennifer L.;
Paulus, Martin P.;
Khalsa, Sahib S.

Publication type:

Article

A mathematical model of local and global attention in natural scene viewing.

Published in:

PLoS Computational Biology, 2020, v. 16, n. 12, p. 1, doi. 10.1371/journal.pcbi.1007880

By:

Malem-Shinitski, Noa;
Opper, Manfred;
Reich, Sebastian;
Schwetlick, Lisa;
Seelig, Stefan A.;
Engbert, Ralf

Publication type:

Article

Bursting in cerebellar stellate cells induced by pharmacological agents: Non-sequential spike adding.

Published in:

PLoS Computational Biology, 2020, v. 16, n. 12, p. 1, doi. 10.1371/journal.pcbi.1008463

By:

Farjami, Saeed;
Alexander, Ryan P. D.;
Bowie, Derek;
Khadra, Anmar

Publication type:

Article

Proteostasis is adaptive: Balancing chaperone holdases against foldases.

Published in:

PLoS Computational Biology, 2020, v. 16, n. 12, p. 1, doi. 10.1371/journal.pcbi.1008460

By:

de Graff, Adam MR;
Mosedale, David E.;
Sharp, Tilly;
Dill, Ken A.;
Grainger, David J.

Publication type:

Article