Works matching IS 15524949 AND DT 2016 AND VI 90 AND IP 2

Results: 20

How validated receptor occupancy flow cytometry assays can impact decisions and support drug development.

Published in:

Cytometry. Part B, 2016, v. 90, n. 2, p. 150, doi. 10.1002/cyto.b.21320

By:

Moulard, Maxime;
Ozoux, Marie‐Laure

Publication type:

Article

Consistent, multi-instrument single tube quantification of CD20 in antibody bound per cell based on CD4 reference.

Published in:

Cytometry. Part B, 2016, v. 90, n. 2, p. 159, doi. 10.1002/cyto.b.21253

By:

Degheidy, Heba;
Abbasi, Fatima;
Mostowski, Howard;
Gaigalas, Adolfas K.;
Marti, Gerald;
Bauer, Steven;
Wang, Lili

Publication type:

Article

Receptor occupancy assessment by flow cytometry as a pharmacodynamic biomarker in biopharmaceutical development.

Published in:

Cytometry. Part B, 2016, v. 90, n. 2, p. 117, doi. 10.1002/cyto.b.21259

By:

Liang, Meina;
Schwickart, Martin;
Schneider, Amy K.;
Vainshtein, Inna;
Del Nagro, Christopher;
Standifer, Nathan;
Roskos, Lorin K.

Publication type:

Article

Evaluation of assay interference and interpretation of CXCR4 receptor occupancy results in a preclinical study with MEDI3185, a fully human antibody to CXCR4.

Published in:

Cytometry. Part B, 2016, v. 90, n. 2, p. 209, doi. 10.1002/cyto.b.21327

By:

Schwickart, Martin;
Chavez, Carlos;
Henderson, Simon;
Vainshtein, Inna;
Standifer, Nathan;
DelNagro, Christopher;
Mehrzai, Freshta;
Schneider, Amy;
Roskos, Lorin;
Liang, Meina

Publication type:

Article

A weighted method for estimation of receptor occupancy for pharmacodynamic measurements in drug development.

Published in:

Cytometry. Part B, 2016, v. 90, n. 2, p. 220, doi. 10.1002/cyto.b.21277

By:

Sternebring, Ola;
Alifrangis, Lene;
Christensen, Toke Folke;
Ji, Hong;
Hegelund, Anne Charlotte;
Högerkorp, Carl‐Magnus

Publication type:

Article

Announcing the 2015 Wallace H. Coulter distinguished lecture award recipient.

Published in:: Cytometry. Part B, 2016, v. 90, n. 2, p. 105, doi. 10.1002/cyto.b.21290
Publication type:: Article

Editors' annual best original paper award.

Published in:: Cytometry. Part B, 2016, v. 90, n. 2, p. 106, doi. 10.1002/cyto.b.21291
Publication type:: Article

ICCS e-newsletter.

Published in:: Cytometry. Part B, 2016, v. 90, n. 2, p. 107, doi. 10.1002/cyto.b.21292
Publication type:: Article

Receptor occupancy by flow cytometry.

Published in:

Cytometry. Part B, 2016, v. 90, n. 2, p. 108, doi. 10.1002/cyto.b.21364

By:

Litwin, Virginia;
Green, Cherie;
Stewart, Jennifer J.

Publication type:

Article

Receptor occupancy and blocking of STAT5 signaling by an anti- IL-7 receptor α antibody in cynomolgus monkeys.

Published in:

Cytometry. Part B, 2016, v. 90, n. 2, p. 191, doi. 10.1002/cyto.b.21247

By:

Kern, Brent;
Li, Wenlin;
Bono, Christine;
Lee, Li‐Fen;
Kraynov, Eugenia

Publication type:

Article

Mathematical modeling of receptor occupancy data: A valuable technology for biotherapeutic drug development.

Published in:

Cytometry. Part B, 2016, v. 90, n. 2, p. 230, doi. 10.1002/cyto.b.21318

By:

Spilker, Mary E.;
Singh, Pratap;
Vicini, Paolo

Publication type:

Article

Multiplexing of receptor occupancy measurements for pharmacodynamic biomarker assessment of biopharmaceuticals.

Published in:

Cytometry. Part B, 2016, v. 90, n. 2, p. 128, doi. 10.1002/cyto.b.21319

By:

Vainshtein, Inna;
Schneider, Amy K.;
Sun, Bo;
Schwickart, Martin;
Roskos, Lorin K.;
Liang, Meina

Publication type:

Article

Validation of a flow cytometry-based assay to assess C5aR receptor occupancy on neutrophils and monocytes for use in drug development.

Published in:

Cytometry. Part B, 2016, v. 90, n. 2, p. 177, doi. 10.1002/cyto.b.21260

By:

Quadrini, Karen J.;
Hegelund, Anne Charlotte;
Cortes, Kasia E.;
Xue, Chengsen;
Kennelly, Susan M.;
Ji, Hong;
Högerkorp, Carl‐Magnus;
Mc Closkey, Thomas W.

Publication type:

Article

Saturation monitoring of VX15/2503, a novel semaphorin 4 D-specific antibody, in clinical trials.

Published in:

Cytometry. Part B, 2016, v. 90, n. 2, p. 199, doi. 10.1002/cyto.b.21338

By:

Fisher, Terrence L.;
Seils, Jennifer;
Reilly, Christine;
Litwin, Virginia;
Green, Lisa;
Salkowitz‐Bokal, Janelle;
Walsh, Robin;
Harville, Sarah;
Leonard, John E.;
Smith, Ernest;
Zauderer, Maurice

Publication type:

Article

Recommendations for the development and validation of flow cytometry-based receptor occupancy assays.

Published in:

Cytometry. Part B, 2016, v. 90, n. 2, p. 141, doi. 10.1002/cyto.b.21339

By:

Green, Cherie L.;
Stewart, Jennifer J.;
Högerkorp, Carl‐Magnus;
Lackey, Alan;
Jones, Nicholas;
Liang, Meina;
Xu, Yuanxin;
Ferbas, John;
Moulard, Maxime;
Czechowska, Kamila;
Mc Closkey, Thomas W.;
van der Strate, Barry W.A.;
Wilkins, Danice E.C.;
Lanham, David;
Wyant, Timothy;
Litwin, Virginia

Publication type:

Article

Editorial board.

Published in:: Cytometry. Part B, 2016, v. 90, n. 2, p. 101, doi. 10.1002/cyto.b.21287
Publication type:: Article

Table of contents.

Published in:: Cytometry. Part B, 2016, v. 90, n. 2, p. 102, doi. 10.1002/cyto.b.21288
Publication type:: Article

Publication schedule for 2016.

Published in:: Cytometry. Part B, 2016, v. 90, n. 2, p. 104, doi. 10.1002/cyto.b.21289
Publication type:: Article

Role of receptor occupancy assays by flow cytometry in drug development.

Published in:

Cytometry. Part B, 2016, v. 90, n. 2, p. 110, doi. 10.1002/cyto.b.21355

By:

Stewart, Jennifer J.;
Green, Cherie L.;
Jones, Nicholas;
Liang, Meina;
Xu, Yuanxin;
Wilkins, Danice E. C.;
Moulard, Maxime;
Czechowska, Kamila;
Lanham, David;
McCloskey, Thomas W.;
Ferbas, John;
van der Strate, Barry. W. A.;
Högerkorp, Carl‐Magnus;
Wyant, Timothy;
Lackey, Alan;
Litwin, Virginia

Publication type:

Article

Development and validation of receptor occupancy pharmacodynamic assays used in the clinical development of the monoclonal antibody vedolizumab.

Published in:

Cytometry. Part B, 2016, v. 90, n. 2, p. 168, doi. 10.1002/cyto.b.21236

By:

Wyant, Tim;
Estevam, Jose;
Yang, Lili;
Rosario, Maria

Publication type:

Article