Found: 21

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  • A selective inhibitor of PRMT5 with in vivo and in vitro potency in MCL models.

    Published in:
    Nature Chemical Biology, 2015, v. 11, n. 6, p. 432, doi. 10.1038/nchembio.1810
    By:
    • Chan-Penebre, Elayne;
    • Kuplast, Kristy G;
    • Majer, Christina R;
    • Boriack-Sjodin, P Ann;
    • Wigle, Tim J;
    • Johnston, L Danielle;
    • Rioux, Nathalie;
    • Munchhof, Michael J;
    • Jin, Lei;
    • Jacques, Suzanne L;
    • West, Kip A;
    • Lingaraj, Trupti;
    • Stickland, Kimberly;
    • Ribich, Scott A;
    • Raimondi, Alejandra;
    • Scott, Margaret Porter;
    • Waters, Nigel J;
    • Pollock, Roy M;
    • Smith, Jesse J;
    • Barbash, Olena
    Publication type:
    Article

  • Pharmacodynamics: Which trails are your drugs taking?

    Published in:
    Nature Chemical Biology, 2015, v. 11, n. 6, p. 382, doi. 10.1038/nchembio.1795
    By:
    • Zhang, Rumin
    Publication type:
    Article

  • Translating slow-binding inhibition kinetics into cellular and in vivo effects.

    Published in:
    Nature Chemical Biology, 2015, v. 11, n. 6, p. 416, doi. 10.1038/nchembio.1796
    By:
    • Walkup, Grant K;
    • You, Zhiping;
    • Ross, Philip L;
    • Allen, Eleanor K H;
    • Daryaee, Fereidoon;
    • Hale, Michael R;
    • O'Donnell, John;
    • Ehmann, David E;
    • Schuck, Virna J A;
    • Buurman, Ed T;
    • Choy, Allison L;
    • Hajec, Laurel;
    • Murphy-Benenato, Kerry;
    • Marone, Valerie;
    • Patey, Sara A;
    • Grosser, Lena A;
    • Johnstone, Michele;
    • Walker, Stephen G;
    • Tonge, Peter J;
    • Fisher, Stewart L
    Publication type:
    Article

  • Voices of chemical biology.

    Published in:
    Nature Chemical Biology, 2015, v. 11, n. 6, p. 378, doi. 10.1038/nchembio.1820
    Publication type:
    Article

  • Catalytic mechanism of a retinoid isomerase essential for vertebrate vision.

    Published in:
    Nature Chemical Biology, 2015, v. 11, n. 6, p. 409, doi. 10.1038/nchembio.1799
    By:
    • Kiser, Philip D;
    • Zhang, Jianye;
    • Badiee, Mohsen;
    • Li, Qingjiang;
    • Shi, Wuxian;
    • Sui, Xuewu;
    • Golczak, Marcin;
    • Tochtrop, Gregory P;
    • Palczewski, Krzysztof
    Publication type:
    Article

  • Archaeochemistry: Raising a glass.

    Published in:
    Nature Chemical Biology, 2015, v. 11, n. 6, p. 380, doi. 10.1038/nchembio.1827
    By:
    • Sheppard, Terry L.
    Publication type:
    Article

  • Proteostasis: Found in translation.

    Published in:
    Nature Chemical Biology, 2015, v. 11, n. 6, p. 380, doi. 10.1038/nchembio.1826
    By:
    • Bucci, Mirella
    Publication type:
    Article

  • Application guide for omics approaches to cell signaling.

    Published in:
    Nature Chemical Biology, 2015, v. 11, n. 6, p. 387, doi. 10.1038/nchembio.1809
    By:
    • Yao, Zhong;
    • Petschnigg, Julia;
    • Ketteler, Robin;
    • Stagljar, Igor
    Publication type:
    Article

  • Brain cancer: Staying alive.

    Published in:
    Nature Chemical Biology, 2015, v. 11, n. 6, p. 381, doi. 10.1038/nchembio.1824
    By:
    • Miura, Grant
    Publication type:
    Article

  • Greatest hits.

    Published in:
    Nature Chemical Biology, 2015, v. 11, n. 6, p. 364, doi. 10.1038/nchembio.1815
    Publication type:
    Article

  • What's in a name?

    Published in:
    Nature Chemical Biology, 2015, v. 11, n. 6, p. 363, doi. 10.1038/nchembio.1832
    Publication type:
    Article

  • Cell motility: Bigger and faster.

    Published in:
    Nature Chemical Biology, 2015, v. 11, n. 6, p. 381, doi. 10.1038/nchembio.1828
    By:
    • Bucci, Mirella
    Publication type:
    Article

  • Enzyme pathways: C1 metabolism redesigned.

    Published in:
    Nature Chemical Biology, 2015, v. 11, n. 6, p. 384, doi. 10.1038/nchembio.1819
    By:
    • Tai, Yi-Shu;
    • Zhang, Kechun
    Publication type:
    Article

  • Know your target, know your molecule.

    Published in:
    Nature Chemical Biology, 2015, v. 11, n. 6, p. 368, doi. 10.1038/nchembio.1813
    By:
    • Bunnage, Mark E;
    • Gilbert, Adam M;
    • Jones, Lyn H;
    • Hett, Erik C
    Publication type:
    Article

  • Mode of action and pharmacogenomic biomarkers for exceptional responders to didemnin B.

    Published in:
    Nature Chemical Biology, 2015, v. 11, n. 6, p. 401, doi. 10.1038/nchembio.1797
    By:
    • Potts, Malia B;
    • McMillan, Elizabeth A;
    • Rosales, Tracy I;
    • Kim, Hyun Seok;
    • Ou, Yi-Hung;
    • Toombs, Jason E;
    • Brekken, Rolf A;
    • Minden, Mark D;
    • MacMillan, John B;
    • White, Michael A
    Publication type:
    Article

  • HIV gp41-mediated membrane fusion occurs at edges of cholesterol-rich lipid domains.

    Published in:
    Nature Chemical Biology, 2015, v. 11, n. 6, p. 424, doi. 10.1038/nchembio.1800
    By:
    • Yang, Sung-Tae;
    • Kiessling, Volker;
    • Simmons, James A;
    • White, Judith M;
    • Tamm, Lukas K
    Publication type:
    Article

  • The use of ene adducts to study and engineer enoyl-thioester reductases.

    Published in:
    Nature Chemical Biology, 2015, v. 11, n. 6, p. 398, doi. 10.1038/nchembio.1794
    By:
    • Rosenthal, Raoul G;
    • Vögeli, Bastian;
    • Quade, Nick;
    • Capitani, Guido;
    • Kiefer, Patrick;
    • Vorholt, Julia A;
    • Ebert, Marc-Olivier;
    • Erb, Tobias J
    Publication type:
    Article

  • Carbohydrates: Inhibitors in an instant.

    Published in:
    Nature Chemical Biology, 2015, v. 11, n. 6, p. 381, doi. 10.1038/nchembio.1825
    By:
    • Goodman, Catherine
    Publication type:
    Article

  • Membrane fusion: A new role for lipid domains?

    Published in:
    Nature Chemical Biology, 2015, v. 11, n. 6, p. 383, doi. 10.1038/nchembio.1812
    By:
    • London, Erwin
    Publication type:
    Article

  • Protein structure/folding: Shape your duty.

    Published in:
    Nature Chemical Biology, 2015, v. 11, n. 6, p. 380, doi. 10.1038/nchembio.1829
    By:
    • Eggleston, Angela K.
    Publication type:
    Article

  • Layers of structure and function in protein aggregation.

    Published in:
    Nature Chemical Biology, 2015, v. 11, n. 6, p. 373, doi. 10.1038/nchembio.1818
    By:
    • Tanaka, Motomasa;
    • Komi, Yusuke
    Publication type:
    Article