Works matching IS 15507416 AND DT 2022 AND VI 24 AND IP 1

Results: 35

Application of Solubility and Dissolution Profile Comparison for Prediction of Gastric pH-Mediated Drug-Drug Interactions.

Published in:

AAPS Journal, 2022, v. 24, n. 1, p. 1, doi. 10.1208/s12248-022-00684-3

By:

Miao, Lei;
Wu, Fang;
Yang, Xinning;
Mousa, Youssef M;
Ramamoorthy, Anuradha;
Lee, Sue-Chih;
Raines, Kimberly;
Zhang, Lei;
Seo, Paul

Publication type:

Article

Analytical Quality by Design, Life Cycle Management, and Method Control.

Published in:

AAPS Journal, 2022, v. 24, n. 1, p. 1, doi. 10.1208/s12248-022-00685-2

By:

Verch, Thorsten;
Campa, Cristiana;
Chéry, Cyrille C.;
Frenkel, Ruth;
Graul, Timothy;
Jaya, Nomalie;
Nakhle, Bassam;
Springall, Jeremy;
Starkey, Jason;
Wypych, Jette;
Ranheim, Todd

Publication type:

Article

Pulmonary Delivery of Aerosolized Chloroquine and Hydroxychloroquine to Treat COVID-19: In Vitro Experimentation to Human Dosing Predictions.

Published in:

AAPS Journal, 2022, v. 24, n. 1, p. 1, doi. 10.1208/s12248-021-00666-x

By:

Kolli, Aditya R.;
Semren, Tanja Zivkovic;
Bovard, David;
Majeed, Shoaib;
van der Toorn, Marco;
Scheuner, Sophie;
Guy, Philippe A.;
Kuczaj, Arkadiusz;
Mazurov, Anatoly;
Frentzel, Stefan;
Calvino-Martin, Florian;
Ivanov, Nikolai V.;
O’Mullane, John;
Peitsch, Manuel C.;
Hoeng, Julia

Publication type:

Article

Correction to: Reactive Oxygen Species–Responsive Celastrol-Loaded Bilirubin Nanoparticles for the Treatment of Rheumatoid Arthritis.

Published in:

2022

By:

Zhao, Xuan;
Huang, Chengyuan;
Su, Meiling;
Ran, Yu;
Wang, Ying;
Yin, Zongning

Publication type:

Correction Notice

The Perspective of DMPK on Recombinant Adeno-Associated Virus-Based Gene Therapy: Past Learning, Current Support, and Future Contribution.

Published in:

AAPS Journal, 2022, v. 24, n. 1, p. 1, doi. 10.1208/s12248-021-00678-7

By:

Chen, Nancy;
Sun, Kefeng;
Chemuturi, Nagendra Venkata;
Cho, Hyelim;
Xia, Cindy Q.

Publication type:

Article

Nfe2l2 Regulates Metabolic Rewiring and Epigenetic Reprogramming in Mediating Cancer Protective Effect by Fucoxanthin.

Published in:

AAPS Journal, 2022, v. 24, n. 1, p. 1, doi. 10.1208/s12248-022-00679-0

By:

Wang, Lujing;
Wu, Renyi;
Sargsyan, Davit;
Su, Shan;
Kuo, Hsiao-Chen;
Li, Shanyi;
Chou, Pochung;
Sarwar, Md Shahid;
Phadnis, Ameya;
Wang, Yujue;
Su, Xiaoyang;
Kong, Ah-Ng

Publication type:

Article

Correction to: Quantitative Systems Pharmacology Modeling of Avadomide-Induced Neutropenia Enables Virtual Clinical Dose and Schedule Finding Studies.

Published in:

2022

By:

Abbiati, Roberto A.;
Pourdehnad, Michael;
Carrancio, Soraya;
Pierce, Daniel W.;
Kasibhatla, Shailaja;
McConnell, Mark;
Trotter, Matthew W. B.;
Loos, Remco;
Santini, Cristina C.;
Ratushny, Alexander V.

Publication type:

Correction Notice

In Vitro to In Vivo Extrapolation Linked to Physiologically Based Pharmacokinetic Models for Assessing the Brain Drug Disposition.

Published in:

AAPS Journal, 2022, v. 24, n. 1, p. 1, doi. 10.1208/s12248-021-00675-w

By:

Murata, Yukiko;
Neuhoff, Sibylle;
Rostami-Hodjegan, Amin;
Takita, Hiroyuki;
Al-Majdoub, Zubida M.;
Ogungbenro, Kayode

Publication type:

Article

Predicting Food Effects: Are We There Yet?

Published in:

AAPS Journal, 2022, v. 24, n. 1, p. 1, doi. 10.1208/s12248-021-00674-x

By:

Emami Riedmaier, Arian

Publication type:

Article

Performance Evaluation of Montelukast Pediatric Formulations: Part II — a PBPK Modelling Approach.

Published in:

AAPS Journal, 2022, v. 24, n. 1, p. 1, doi. 10.1208/s12248-021-00662-1

By:

Guimarães, Mariana;
Vertzoni, Maria;
Fotaki, Nikoletta

Publication type:

Article

Performance Evaluation of Montelukast Pediatric Formulations: Part I—Age-Related In Vitro Conditions.

Published in:

AAPS Journal, 2022, v. 24, n. 1, p. 1, doi. 10.1208/s12248-021-00661-2

By:

Guimarães, Mariana;
Somville, Pascal;
Vertzoni, Maria;
Fotaki, Nikoletta

Publication type:

Article

Nano/microparticle Formulations for Universal Influenza Vaccines.

Published in:

AAPS Journal, 2022, v. 24, n. 1, p. 1, doi. 10.1208/s12248-021-00676-9

By:

Hendy, Dylan A.;
Amouzougan, Eva A.;
Young, Isabella C.;
Bachelder, Eric M.;
Ainslie, Kristy M.

Publication type:

Article

Proof of Concept in Assignment of Within-Subject Variability During Virtual Bioequivalence Studies: Propagation of Intra-Subject Variation in Gastrointestinal Physiology Using Physiologically Based Pharmacokinetic Modeling.

Published in:

AAPS Journal, 2022, v. 24, n. 1, p. 1, doi. 10.1208/s12248-021-00672-z

By:

Bego, Margareta;
Patel, Nikunjkumar;
Cristofoletti, Rodrigo;
Rostami-Hodjegan, Amin

Publication type:

Article

Assessment of Functional Characterization and Comparability of Biotherapeutics: a Review.

Published in:

AAPS Journal, 2022, v. 24, n. 1, p. 1, doi. 10.1208/s12248-021-00671-0

By:

Dash, Rozaleen;
Singh, Sumit Kumar;
Chirmule, Narendra;
Rathore, Anurag S.

Publication type:

Article

Evaluation of Excipient Risk in BCS Class I and III Biowaivers.

Published in:

AAPS Journal, 2022, v. 24, n. 1, p. 1, doi. 10.1208/s12248-021-00670-1

By:

Metry, Melissa;
Polli, James E.

Publication type:

Article

A Full Evaporation Static Headspace Gas Chromatography Method with Nitrogen Phosphorous Detection for Ultrasensitive Analysis of Semi-volatile Nitrosamines in Pharmaceutical Products.

Published in:

AAPS Journal, 2022, v. 24, n. 1, p. 1, doi. 10.1208/s12248-021-00669-8

By:

Zheng, Jinjian;
Kirkpatrick, Christine L.;
Lee, Daniel;
Han, Xinxin;
Martinez, Ana I.;
Gallagher, Kimberly;
Evans, Rebecca K.;
Mudur, Sanjay V.;
Liang, Xihui;
Drake, Jennifer;
Buhler, Leah A.;
Mowery, Mark D.

Publication type:

Article

Flux-Based Formulation Development—A Proof of Concept Study.

Published in:

AAPS Journal, 2022, v. 24, n. 1, p. 1, doi. 10.1208/s12248-021-00668-9

By:

Kádár, Szabina;
Tőzsér, Petra;
Nagy, Brigitta;
Farkas, Attila;
Nagy, Zsombor K.;
Tsinman, Oksana;
Tsinman, Konstantin;
Csicsák, Dóra;
Völgyi, Gergely;
Takács-Novák, Krisztina;
Borbás, Enikő;
Sinkó, Bálint

Publication type:

Article

Exploring the Relationship of Drug BCS Classification, Food Effect, and Gastric pH-Dependent Drug Interactions.

Published in:

AAPS Journal, 2022, v. 24, n. 1, p. 1, doi. 10.1208/s12248-021-00667-w

By:

Owens, Katie;
Argon, Sophie;
Yu, Jingjing;
Yang, Xinning;
Wu, Fang;
Lee, Sue-Chih;
Sun, Wei-Jhe;
Ramamoorthy, Anuradha;
Zhang, Lei;
Ragueneau-Majlessi, Isabelle

Publication type:

Article

Navigating Through Cell-Based In vitro Models Available for Prediction of Intestinal Permeability and Metabolism: Are We Ready for 3D?

Published in:

AAPS Journal, 2022, v. 24, n. 1, p. 1, doi. 10.1208/s12248-021-00665-y

By:

Franco, Yesenia L.;
Da Silva, Lais;
Cristofoletti, Rodrigo

Publication type:

Article

Comparison of Predictions by BCS, rDCS and Machine Learning for the Effect of Food on Oral Drug Absorption Based on Features Calculated In silico.

Published in:

AAPS Journal, 2022, v. 24, n. 1, p. 1, doi. 10.1208/s12248-021-00664-z

By:

Hoshino, Yusuke;
Yoshioka, Hideki;
Hisaka, Akihiro

Publication type:

Article

PBPK Simulation-Based Evaluation of Ganciclovir Crystalluria Risk Factors: Effect of Renal Impairment, Old Age, and Low Fluid Intake.

Published in:

AAPS Journal, 2022, v. 24, n. 1, p. 1, doi. 10.1208/s12248-021-00654-1

By:

Scotcher, Daniel;
Galetin, Aleksandra

Publication type:

Article

Dissolution Challenges Associated with the Surface pH of Drug Particles: Integration into Mechanistic Oral Absorption Modeling.

Published in:

AAPS Journal, 2022, v. 24, n. 1, p. 1, doi. 10.1208/s12248-021-00663-0

By:

Hens, Bart;
Seegobin, Nidhi;
Bermejo, Marival;
Tsume, Yasuhiro;
Clear, Nicola;
McAllister, Mark;
Amidon, Gregory E.;
Amidon, Gordon L.

Publication type:

Article

Predicting the Drug–Drug Interaction Mediated by CYP3A4 Inhibition: Method Development and Performance Evaluation.

Published in:

AAPS Journal, 2022, v. 24, n. 1, p. 1, doi. 10.1208/s12248-021-00659-w

By:

Ren, Hong-can;
Sai, Yang;
Chen, Tao;
Zhang, Chun;
Tang, Lily;
Yang, Cheng-guang

Publication type:

Article

Innovative Design and Analysis for PK/PD Biosimilar Bridging Studies with Multiple References.

Published in:

AAPS Journal, 2022, v. 24, n. 1, p. 1, doi. 10.1208/s12248-021-00658-x

By:

Song, Fuyu;
Zheng, Xin;
Wang, Yujia;
Chow, Shein-Chung;
Sun, Hongqiang

Publication type:

Article

Assessment of the Kochak-Benet Equation for Hepatic Clearance for the Parallel-Tube Model: Relevance of Classic Clearance Concepts in PK and PBPK.

Published in:

AAPS Journal, 2022, v. 24, n. 1, p. 1, doi. 10.1208/s12248-021-00656-z

By:

Jusko, William J.;
Li, Xiaonan

Publication type:

Article

Correction to: Can Pharmacokinetic Studies Assess the Pulmonary Fate of Dry Powder Inhaler Formulations of Fluticasone Propionate?

Published in:

2022

By:

Hochhaus, Günther;
Chen, Mong-Jen;
Kurumaddali, Abhinav;
Schilling, Uta;
Jiao, Yuanyuan;
Drescher, Stefanie K.;
Amini, Elham;
Berger, Simon M.;
Kandala, Bhargava;
Tabulov, Christine;
Shao, Jie;
Seay, Brandon;
Abu-Hasan, Mutasim N.;
Baumstein, Sandra M.;
Winner, Lawrence;
Shur, Jagdeep;
Price, Robert;
Hindle, Michael;
Wei, Xiangyin;
Carrasco, Cynthia

Publication type:

Correction Notice

Efficacy and Safety Exposure–Response Analysis of Loncastuximab Tesirine in Patients with B cell non-Hodgkin Lymphoma.

Published in:

AAPS Journal, 2022, v. 24, n. 1, p. 1, doi. 10.1208/s12248-021-00660-3

By:

Hess, Brian;
Townsend, William;
Ai, Weiyun;
Stathis, Anastasios;
Solh, Melhem;
Alderuccio, Juan Pablo;
Ungar, David;
Liao, Sam;
Liao, Lori;
Khouri, Lisa;
Zhang, Xiaoyan;
Boni, Joseph

Publication type:

Article

Development of Lipidoid Nanoparticles for siRNA Delivery to Neural Cells.

Published in:

AAPS Journal, 2022, v. 24, n. 1, p. 1, doi. 10.1208/s12248-021-00653-2

By:

Khare, Purva;
Dave, Kandarp M.;
Kamte, Yashika S.;
Manoharan, Muthiah A.;
O'Donnell, Lauren A.;
Manickam, Devika S.

Publication type:

Article

Zwitterionic Polymer Coatings Enhance Gold Nanoparticle Stability and Uptake in Various Biological Environments.

Published in:

AAPS Journal, 2022, v. 24, n. 1, p. 1, doi. 10.1208/s12248-021-00652-3

By:

King, Benjamin M.;
Fiegel, Jennifer

Publication type:

Article

Anti-drug Antibody Validation Testing and Reporting Harmonization.

Published in:

AAPS Journal, 2022, v. 24, n. 1, p. 1, doi. 10.1208/s12248-021-00649-y

By:

Myler, Heather;
Pedras-Vasconcelos, João;
Phillips, Kelli;
Hottenstein, Charles Scott;
Chamberlain, Paul;
Devanaryan, Viswanath;
Gleason, Carol;
Goodman, Joanne;
Manning, Marta Starcevic;
Purushothama, Shobha;
Richards, Susan;
Shen, Honglue;
Zoghbi, Jad;
Amaravadi, Lakshmi;
Barger, Troy;
Bowen, Steven;
Bowsher, Ronald R.;
Clements-Egan, Adrienne;
Geng, Dong;
Goletz, Theresa J.

Publication type:

Article

Microfluidic-Generated Immunomodulatory Nanoparticles and Formulation-Dependent Effects on Lipopolysaccharide-Induced Macrophage Inflammation.

Published in:

AAPS Journal, 2022, v. 24, n. 1, p. 1, doi. 10.1208/s12248-021-00645-2

By:

Truong, Nhu;
Black, Sheneil K.;
Shaw, Jacob;
Scotland, Brianna L.;
Pearson, Ryan M.

Publication type:

Article

Machine Learning and Artificial Intelligence in Pharmaceutical Research and Development: a Review.

Published in:

AAPS Journal, 2022, v. 24, n. 1, p. 1, doi. 10.1208/s12248-021-00644-3

By:

Kolluri, Sheela;
Lin, Jianchang;
Liu, Rachael;
Zhang, Yanwei;
Zhang, Wenwen

Publication type:

Article

Systematic Evaluation of the Effect of Formulation Variables on In Vitro Performance of Mometasone Furoate Suspension-Metered Dose Inhalers.

Published in:

AAPS Journal, 2022, v. 24, n. 1, p. 1, doi. 10.1208/s12248-021-00638-1

By:

Bachhav, Sagar S.;
Sheth, Poonam;
Sandell, Dennis;
Svensson, Mårten;
Bhagwat, Sharvari;
Conti, Denise S.;
Oguntimein, Oluwamurewa;
Dhapare, Sneha;
Saluja, Bhawana;
Winner, Lawrence;
Bulitta, Jürgen B.;
Hochhaus, Guenther

Publication type:

Article

A Novel Approach for Quantifying the Pharmacological Activity of T-Cell Engagers Utilizing In Vitro Time Course Experiments and Streamlined Data Analysis.

Published in:

AAPS Journal, 2022, v. 24, n. 1, p. 1, doi. 10.1208/s12248-021-00637-2

By:

Van De Vyver, Arthur;
Eigenmann, Miro;
Ovacik, Meric;
Pohl, Christian;
Herter, Sylvia;
Weinzierl, Tina;
Fauti, Tanja;
Klein, Christian;
Lehr, Thorsten;
Bacac, Marina;
Walz, Antje-Christine

Publication type:

Article

Reactive Oxygen Species–Responsive Celastrol-Loaded: Bilirubin Nanoparticles for the Treatment of Rheumatoid Arthritis.

Published in:

AAPS Journal, 2022, v. 24, n. 1, p. 1, doi. 10.1208/s12248-021-00636-3

By:

Zhao, Xuan;
Huang, Chengyuan;
Su, Meiling;
Ran, Yu;
Wang, Ying;
Yin, Zongning

Publication type:

Article