Works matching IS 15507416 AND DT 2021 AND VI 23 AND IP 1

Results: 25

Iontophoresis to Overcome the Challenge of Nail Permeation: Considerations and Optimizations for Successful Ungual Drug Delivery.

Published in:

AAPS Journal, 2021, v. 23, n. 1, p. 1, doi. 10.1208/s12248-020-00552-y

By:

Chen, Kevin;
Puri, Vinam;
Michniak-Kohn, Bozena

Publication type:

Article

Human Fetal Liver Metabolism of Oxycodone Is Mediated by CYP3A7.

Published in:

AAPS Journal, 2021, v. 23, n. 1, p. 1, doi. 10.1208/s12248-020-00537-x

By:

Shum, Sara;
Isoherranen, Nina

Publication type:

Article

γ-Hydroxybutyric Acid: Pharmacokinetics, Pharmacodynamics, and Toxicology.

Published in:

AAPS Journal, 2021, v. 23, n. 1, p. 1, doi. 10.1208/s12248-020-00543-z

By:

Felmlee, Melanie A.;
Morse, Bridget L.;
Morris, Marilyn E.

Publication type:

Article

Population Pharmacokinetics of Intracellular 5-Fluorouridine 5′-Triphosphate and its Relationship with Hand-and-Foot Syndrome in Patients Treated with Capecitabine.

Published in:

AAPS Journal, 2021, v. 23, n. 1, p. 1, doi. 10.1208/s12248-020-00533-1

By:

Janssen, Julie M.;
Jacobs, Bart A. W.;
Roosendaal, Jeroen;
Derissen, Ellen J. B.;
Marchetti, Serena;
Beijnen, Jos H.;
Huitema, Alwin D. R.;
Dorlo, Thomas P. C.

Publication type:

Article

A Novel Total Drug Assay for Quantification of Anti-C5 Therapeutic Monoclonal Antibody in the Presence of Abundant Target.

Published in:

AAPS Journal, 2021, v. 23, n. 1, p. 1, doi. 10.1208/s12248-020-00539-9

By:

Watanabe, Hiroo;
Shibuya, Mitsuko;
Shibahara, Norihito;
Ruike, Yoshinao;
Sampei, Zenjiro;
Haraya, Kenta;
Tachibana, Tatsuhiko;
Wakabayashi, Tetsuya;
Sakamoto, Akihisa;
Tsunoda, Hiroyuki;
Murao, Naoaki

Publication type:

Article

The Role of Alcohol Dehydrogenase in Drug Metabolism: Beyond Ethanol Oxidation.

Published in:

AAPS Journal, 2021, v. 23, n. 1, p. 1, doi. 10.1208/s12248-020-00536-y

By:

Di, Li;
Balesano, Amanda;
Jordan, Samantha;
Shi, Sophia M.

Publication type:

Article

Skin Penetration Enhancement Strategies Used in the Development of Melanoma Topical Treatments.

Published in:

AAPS Journal, 2021, v. 23, n. 1, p. 1, doi. 10.1208/s12248-020-00544-y

By:

Tambunlertchai, Supreeda;
Geary, Sean M.;
Salem, Aliasger K.

Publication type:

Article

Multiscale and Translational Quantitative Systems Toxicology, Pharmacokinetic-Toxicodynamic Modeling Analysis for Assessment of Doxorubicin-Induced Cardiotoxicity.

Published in:

AAPS Journal, 2021, v. 23, n. 1, p. 1, doi. 10.1208/s12248-020-00542-0

By:

Vaidya, Tanaya R.;
Mody, Hardik;
Franco, Yesenia L.;
Brown, Ashley;
Ait-Oudhia, Sihem

Publication type:

Article

Application of Model Informed Precision Dosing to Address the Impact of Pregnancy Stage and CYP2D6 Phenotype on Foetal Morphine Exposure.

Published in:

AAPS Journal, 2021, v. 23, n. 1, p. 1, doi. 10.1208/s12248-020-00541-1

By:

Badaoui, Sarah;
Hopkins, Ashley M.;
Rodrigues, A David;
Miners, John O.;
Sorich, Michael J.;
Rowland, Andrew

Publication type:

Article

Mouse NTCP–Mediated Rosuvastatin Uptake In Vitro and in Slc10a1-Deficient Mice.

Published in:

AAPS Journal, 2021, v. 23, n. 1, p. 1, doi. 10.1208/s12248-020-00540-2

By:

Russell, Laura E.;
DeGorter, Marianne K.;
Ho, Richard H.;
Leake, Brenda F.;
Schmerk, Crystal L.;
Mansell, Sara E.;
Kim, Richard B.

Publication type:

Article

Isotyping and Semi-Quantitation of Monkey Anti-Drug Antibodies by Immunocapture Liquid Chromatography-Mass Spectrometry.

Published in:

AAPS Journal, 2021, v. 23, n. 1, p. 1, doi. 10.1208/s12248-020-00538-w

By:

Huang, Xiaoxiao;
Xu, Xiaobin;
Partridge, Michael A.;
Chen, Jihua;
Koehler-Stec, Ellen;
Sumner, Giane;
Qiu, Haibo;
Torri, Albert;
Li, Ning

Publication type:

Article

Recent Developments on Therapeutic and Diagnostic Approaches for COVID-19.

Published in:

AAPS Journal, 2021, v. 23, n. 1, p. 1, doi. 10.1208/s12248-020-00532-2

By:

Majumder, Joydeb;
Minko, Tamara

Publication type:

Article

Understanding Mechanisms of Food Effect and Developing Reliable PBPK Models Using a Middle-out Approach.

Published in:

AAPS Journal, 2021, v. 23, n. 1, p. 1, doi. 10.1208/s12248-020-00548-8

By:

Pepin, Xavier J. H.;
Huckle, James E.;
Alluri, Ravindra V.;
Basu, Sumit;
Dodd, Stephanie;
Parrott, Neil;
Emami Riedmaier, Arian

Publication type:

Article

Correction to: Integrated Multi-stakeholder Systems Thinking Strategy: Decision-making with Biopharmaceutics Risk Assessment Roadmap (BioRAM) to Optimize Clinical Performance of Drug Products.

Published in:

2021

By:

Selen, Arzu;
Müllertz, Anette;
Kesisoglou, Filippos;
Ho, Rodney J. Y.;
Cook, Jack A.;
Dickinson, Paul A.;
Flanagan, Talia

Publication type:

Correction Notice

Oil-Immersion Flow Imaging Microscopy for Quantification and Morphological Characterization of Submicron Particles in Biopharmaceuticals.

Published in:

AAPS Journal, 2021, v. 23, n. 1, p. 1, doi. 10.1208/s12248-020-00547-9

By:

Krause, Nils;
Kuhn, Sebastian;
Frotscher, Erik;
Nikels, Felix;
Hawe, Andrea;
Garidel, Patrick;
Menzen, Tim

Publication type:

Article

Population Pharmacodynamic Modeling Using the Sigmoid Emax Model: Influence of Inter-individual Variability on the Steepness of the Concentration–Effect Relationship. a Simulation Study.

Published in:

AAPS Journal, 2021, v. 23, n. 1, p. 1, doi. 10.1208/s12248-020-00549-7

By:

Proost, Johannes H.;
Eleveld, Douglas J.;
Struys, Michel M. R. F.

Publication type:

Article

Comparison of Precision and Accuracy of Five Methods to Analyse Total Score Data.

Published in:

AAPS Journal, 2021, v. 23, n. 1, p. 1, doi. 10.1208/s12248-020-00546-w

By:

Wellhagen, Gustaf J.;
Karlsson, Mats O.;
Kjellsson, Maria C.

Publication type:

Article

Correction to: Drug Absorption Parameters Obtained Using the Isolated Perfused Rat Lung Model Are Predictive of Rat In Vivo Lung Absorption.

Published in:

2021

By:

Eriksson, Johanna;
Sjögren, Erik;
Lennernäs, Hans;
Thörn, Helena

Publication type:

Correction Notice

Correction to: Use of Physiologically Based Pharmacokinetic (PBPK) Modeling for Predicting Drug-Food Interactions: an Industry Perspective.

Published in:

2021

By:

Riedmaier, Arian Emami;
DeMent, Kevin;
Huckle, James;
Bransford, Phil;
Stillhart, Cordula;
Lloyd, Richard;
Alluri, Ravindra;
Basu, Sumit;
Chen, Yuan;
Dhamankar, Varsha;
Dodd, Stephanie;
Kulkarni, Priyanka;
Olivares-Morales, Andrés;
Peng, Chi-Chi;
Pepin, Xavier;
Ren, Xiaojun;
Tran, Thuy;
Tistaert, Christophe;
Heimbach, Tycho;
Kesisoglou, Filippos

Publication type:

Correction Notice

Spinach and Chive for Kidney Tubule Engineering: the Limitations of Decellularized Plant Scaffolds and Vasculature.

Published in:

AAPS Journal, 2021, v. 23, n. 1, p. 1, doi. 10.1208/s12248-020-00550-0

By:

Jansen, Katja;
Evangelopoulou, Marianna;
Pou Casellas, Carla;
Abrishamcar, Sarina;
Jansen, Jitske;
Vermonden, Tina;
Masereeuw, Rosalinde

Publication type:

Article

Inhalable Nanoparticles/Microparticles of an AMPK and Nrf2 Activator for Targeted Pulmonary Drug Delivery as Dry Powder Inhalers.

Published in:

AAPS Journal, 2021, v. 23, n. 1, p. 1, doi. 10.1208/s12248-020-00531-3

By:

Acosta, Maria F.;
Abrahamson, Michael D.;
Encinas-Basurto, David;
Fineman, Jeffrey R.;
Black, Stephen M.;
Mansour, Heidi M.

Publication type:

Article

Albumin-Mediated Uptake Improves Human Clearance Prediction for Hepatic Uptake Transporter Substrates Aiding a Mechanistic In Vitro-In Vivo Extrapolation (IVIVE) Strategy in Discovery Research.

Published in:

AAPS Journal, 2021, v. 23, n. 1, p. 1, doi. 10.1208/s12248-020-00528-y

By:

Li, Na;
Badrinarayanan, Akshay;
Ishida, Kazuya;
Li, Xingwen;
Roberts, John;
Wang, Shuai;
Hayashi, Mike;
Gupta, Anshul

Publication type:

Article

Keytruda and PD-L1: a Real-World Example of Co-development of a Drug with a Predictive Biomarker.

Published in:

AAPS Journal, 2021, v. 23, n. 1, p. 1, doi. 10.1208/s12248-020-00525-1

By:

Emancipator, Kenneth

Publication type:

Article

A Novel Pharmacodynamic Biomarker and Mechanistic Modeling Facilitate the Development of Tovetumab, a Monoclonal Antibody Directed Against Platelet-Derived Growth Factor Receptor Alpha, for Cancer Therapy.

Published in:

AAPS Journal, 2021, v. 23, n. 1, p. 1, doi. 10.1208/s12248-020-00523-3

By:

Liang, Meina;
Wang, Bing;
Schneider, Amy;
Vainshtein, Inna;
Roskos, Lorin

Publication type:

Article

Comparison of the ELISA and ECL Assay for Vedolizumab Anti-drug Antibodies: Assessing the Impact on Pharmacokinetics and Safety Outcomes of the Phase 3 GEMINI Trials.

Published in:

AAPS Journal, 2021, v. 23, n. 1, p. 1, doi. 10.1208/s12248-020-00518-0

By:

Wyant, Timothy;
Yang, Lili;
Rosario, Maria

Publication type:

Article