Works matching IS 15507416 AND DT 2019 AND VI 21 AND IP 3

Results: 21

CAR T Cell Immunotherapy in Human and Veterinary Oncology: Changing the Odds Against Hematological Malignancies.

Published in:

AAPS Journal, 2019, v. 21, n. 3, p. N.PAG, doi. 10.1208/s12248-019-0322-1

By:

Mochel, Jonathan P.;
Ekker, Stephen C.;
Johannes, Chad M.;
Jergens, Albert E.;
Allenspach, Karin;
Bourgois-Mochel, Agnes;
Knouse, Michael;
Benzekry, Sebastien;
Wierson, Wesley;
LeBlanc, Amy K.;
Kenderian, Saad S.

Publication type:

Article

Trial Design and Statistical Considerations on the Assessment of Pharmacodynamic Similarity.

Published in:

AAPS Journal, 2019, v. 21, n. 3, p. N.PAG, doi. 10.1208/s12248-019-0321-2

By:

Zhu, Peijuan;
Hsu, Chyi-Hung;
Liao, Jason;
Xu, Steven;
Zhang, Liping;
Zhou, Honghui

Publication type:

Article

HER3-Targeted Affibodies with Optimized Formats Reduce Ovarian Cancer Progression in a Mouse Xenograft Model.

Published in:

AAPS Journal, 2019, v. 21, n. 3, p. N.PAG, doi. 10.1208/s12248-019-0318-x

By:

Schardt, John S.;
Noonan-Shueh, Madeleine;
Oubaid, Jinan M.;
Pottash, Alex Eli;
Williams, Sonya C.;
Hussain, Arif;
Lapidus, Rena G.;
Lipkowitz, Stanley;
Jay, Steven M.

Publication type:

Article

Neutralizing Antibody Assay Development with High Drug and Target Tolerance to Support Clinical Development of an Anti-TFPI Therapeutic Monoclonal Antibody.

Published in:

AAPS Journal, 2019, v. 21, n. 3, p. N.PAG, doi. 10.1208/s12248-019-0320-3

By:

Xiang, Yuhong;
Parng, Chuenlei;
Olson, Katrina;
Seletskaia, Elena;
Gorovits, Boris;
Jani, Darshana;
Caiazzo, Teresa;
Joyce, Alison;
Donley, Jean

Publication type:

Article

Induction and Impact of Anti-Drug Responses Elicited by a Human Recombinant Coagulation Factor FXa<sup>I16L</sup> in Preclinical Species.

Published in:

AAPS Journal, 2019, v. 21, n. 3, p. N.PAG, doi. 10.1208/s12248-019-0324-z

By:

Parng, Chuenlei;
Bolt, Michael;
Pittman, Debra D.;
Caiazzo, Teresa;
Dyleski, Lisa;
Gorovits, Boris;
Webster, Rob

Publication type:

Article

Dissolution Chamber for Small Drug Delivery System in the Periodontal Pocket.

Published in:

AAPS Journal, 2019, v. 21, n. 3, p. N.PAG, doi. 10.1208/s12248-019-0317-y

By:

Ren, Wei;
Murawsky, Michael;
La Count, Terri;
Wanasathop, Apipa;
Hao, Xin;
Kelm, Gary R.;
Kozak, Darby;
Qin, Bin;
Li, S. Kevin

Publication type:

Article

Mechanisms of CYP3A Induction During Pregnancy: Studies in HepaRG Cells.

Published in:

AAPS Journal, 2019, v. 21, n. 3, p. N.PAG, doi. 10.1208/s12248-019-0316-z

By:

Sachar, Madhav;
Kelly, Edward J.;
Unadkat, Jashvant D.

Publication type:

Article

Bacteriophage PEV20 and Ciprofloxacin Combination Treatment Enhances Removal of Pseudomonas aeruginosa Biofilm Isolated from Cystic Fibrosis and Wound Patients.

Published in:

AAPS Journal, 2019, v. 21, n. 3, p. N.PAG, doi. 10.1208/s12248-019-0315-0

By:

Chang, Rachel Yoon Kyung;
Das, Theerthankar;
Manos, Jim;
Kutter, Elizabeth;
Morales, Sandra;
Chan, Hak-Kim

Publication type:

Article

Theoretical Considerations for Direct Translation of Unbound Liver-to-Plasma Partition Coefficient from In Vitro to In Vivo.

Published in:

AAPS Journal, 2019, v. 21, n. 3, p. N.PAG, doi. 10.1208/s12248-019-0314-1

By:

Li, Zhenhong;
Di, Li;
Maurer, Tristan S.

Publication type:

Article

Effect of Dibasic Calcium Phosphate Incorporation on Cellulose Nanocrystal/Chitosan Hydrogel Properties for the Treatment of Vertebral Compression Fractures.

Published in:

AAPS Journal, 2019, v. 21, n. 3, p. N.PAG, doi. 10.1208/s12248-019-0311-4

By:

Ghavimi, Soheila Ali Akbari;
Lungren, Ethan S.;
Stromsdorfer, Jessica L.;
Darkow, Blake T.;
Nguyen, Julie A.;
Sun, Yisheng;
Pfieffer, Ferris M.;
Goldstein, Christina L.;
Wan, Caixia;
Ulery, Bret D.

Publication type:

Article

Variability Attribution for Automated Model Building.

Published in:

AAPS Journal, 2019, v. 21, n. 3, p. N.PAG, doi. 10.1208/s12248-019-0310-5

By:

Ibrahim, Moustafa M. A.;
Nordgren, Rikard;
Kjellsson, Maria C.;
Karlsson, Mats O.

Publication type:

Article

Simulating the Impact of Elevated Levels of Interleukin-6 on the Pharmacokinetics of Various CYP450 Substrates in Patients with Neuromyelitis Optica or Neuromyelitis Optica Spectrum Disorders in Different Ethnic Populations.

Published in:

AAPS Journal, 2019, v. 21, n. 3, p. N.PAG, doi. 10.1208/s12248-019-0309-y

By:

Machavaram, Krishna K.;
Endo-Tsukude, Chihiro;
Terao, Kimio;
Gill, Katherine L.;
Hatley, Oliver J.;
Gardner, Iain;
Parrott, Neil;
Ducray, Patricia Sanwald

Publication type:

Article

Model-Based Conditional Weighted Residuals Analysis for Structural Model Assessment.

Published in:

AAPS Journal, 2019, v. 21, n. 3, p. N.PAG, doi. 10.1208/s12248-019-0305-2

By:

Ibrahim, Moustafa M. A.;
Ueckert, Sebastian;
Freiberga, Svetlana;
Kjellsson, Maria C.;
Karlsson, Mats O.

Publication type:

Article

Interfacial Stress in the Development of Biologics: Fundamental Understanding, Current Practice, and Future Perspective.

Published in:

AAPS Journal, 2019, v. 21, n. 3, p. N.PAG, doi. 10.1208/s12248-019-0312-3

By:

Li, Jinjiang;
Krause, Mary E.;
Chen, Xiaodong;
Cheng, Yuan;
Dai, Weiguo;
Hill, John J.;
Huang, Min;
Jordan, Susan;
LaCasse, Daniel;
Narhi, Linda;
Shalaev, Evgenyi;
Shieh, Ian C.;
Thomas, Justin C.;
Tu, Raymond;
Zheng, Songyan;
Zhu, Lily

Publication type:

Article

Dissolution Edge Charts for Immediate Release Products and Their Applications: a Simulation Study to Aid the Setting of Specifications.

Published in:

AAPS Journal, 2019, v. 21, n. 3, p. N.PAG, doi. 10.1208/s12248-019-0308-z

By:

Duan, John Z.

Publication type:

Article

A Receiver Operating Characteristic Framework for Non-adherence Detection Using Drug Concentration Thresholds—Application to Simulated Risperidone Data in Schizophrenic Patients.

Published in:

AAPS Journal, 2019, v. 21, n. 3, p. N.PAG, doi. 10.1208/s12248-019-0299-9

By:

Pérez-Ruixo, Carlos;
Remmerie, Bart;
Peréz-Ruixo, Juan José;
Vermeulen, An

Publication type:

Article

A Reappraisal of Sedimentation Nonideality Coefficients for the Analysis of Weak Interactions of Therapeutic Proteins.

Published in:

AAPS Journal, 2019, v. 21, n. 3, p. N.PAG, doi. 10.1208/s12248-019-0307-0

By:

Chaturvedi, Sumit K.;
Schuck, Peter

Publication type:

Article

A Density-Changing Centrifugation Method for Efficient Separation of Free Drugs from Drug-Loaded Particulate Delivery Systems.

Published in:

AAPS Journal, 2019, v. 21, n. 3, p. N.PAG, doi. 10.1208/s12248-019-0306-1

By:

Han, Lu;
Zhan, Hongyan;
Sun, Xun;
Zhang, Zhi-Rong;
Deng, Li

Publication type:

Article

First-Principles and Empirical Approaches to Predicting In Vitro Dissolution for Pharmaceutical Formulation and Process Development and for Product Release Testing.

Published in:

AAPS Journal, 2019, v. 21, n. 3, p. N.PAG, doi. 10.1208/s12248-019-0297-y

By:

Zaborenko, Nikolay;
Shi, Zhenqi;
Corredor, Claudia C.;
Smith-Goettler, Brandye M.;
Zhang, Limin;
Hermans, Andre;
Neu, Colleen M.;
Alam, Md Anik;
Cohen, Michael J.;
Lu, Xujin;
Xiong, Leah;
Zacour, Brian M.

Publication type:

Article

Scaling Drug Clearance from Adults to the Young Children for Drugs Undergoing Hepatic Metabolism: A Simulation Study to Search for the Simplest Scaling Method.

Published in:

AAPS Journal, 2019, v. 21, n. 3, p. N.PAG, doi. 10.1208/s12248-019-0295-0

By:

Calvier, E. A. M.;
Krekels, E. H. J.;
Johnson, T. N.;
Rostami-Hodjegan, A.;
Tibboel, D.;
Knibbe, Catherijne A. J.

Publication type:

Article

Pharmacokinetic Properties of Humanized IgG1 and IgG4 Antibodies in Preclinical Species: Translational Evaluation.

Published in:

AAPS Journal, 2019, v. 21, n. 3, p. N.PAG, doi. 10.1208/s12248-019-0304-3

By:

Tabrizi, Mohammad;
Neupane, Divas;
Elie, Sophia E.;
Shankaran, Harish;
Juan, Veronica;
Zhang, Shuli;
Hseih, SuChun;
Fayadat-Dilman, Laurence;
Zhang, Daping;
Song, Yaoli;
Ganti, Vaishnavi;
Judo, Michael;
Spellman, Daniel;
Seghezzi, Wolfgang;
Escandon, Enrique

Publication type:

Article