Works matching IS 15507416 AND DT 2019 AND VI 21 AND IP 2

Results: 20

Moringa Isothiocyanate Activates Nrf2: Potential Role in Diabetic Nephropathy.

Published in:

AAPS Journal, 2019, v. 21, n. 2, p. 1, doi. 10.1208/s12248-019-0301-6

By:

Cheng, David;
Gao, Linbo;
Su, Shan;
Sargsyan, Davit;
Wu, Renyi;
Raskin, Ilya;
Kong, Ah-Ng

Publication type:

Article

Activation of Protein Kinase A Stimulates SUMOylation, Expression, and Transport Activity of Organic Anion Transporter 3.

Published in:

AAPS Journal, 2019, v. 21, n. 2, p. 1, doi. 10.1208/s12248-019-0303-4

By:

Wang, Haoxun;
Zhang, Jinghui;
You, Guofeng

Publication type:

Article

PBPK Absorption Modeling: Establishing the In Vitro-In Vivo Link—Industry Perspective.

Published in:

AAPS Journal, 2019, v. 21, n. 2, p. 1, doi. 10.1208/s12248-019-0292-3

By:

Stillhart, Cordula;
Pepin, Xavier;
Tistaert, Christophe;
Good, David;
Van Den Bergh, An;
Parrott, Neil;
Kesisoglou, Filippos

Publication type:

Article

Translational Framework Predicting Tumour Response in Gemcitabine-Treated Patients with Advanced Pancreatic and Ovarian Cancer from Xenograft Studies.

Published in:

AAPS Journal, 2019, v. 21, n. 2, p. 1, doi. 10.1208/s12248-018-0291-9

By:

Garcia-Cremades, Maria;
Pitou, Celine;
Iversen, Philip W.;
Troconiz, Iñaki F.

Publication type:

Article

Estimation of Solid Tumor Doubling Times from Progression-Free Survival Plots Using a Novel Statistical Approach.

Published in:

AAPS Journal, 2019, v. 21, n. 2, p. 1, doi. 10.1208/s12248-019-0302-5

By:

Kay, Katherine;
Dolcy, Keith;
Bies, Robert;
Shah, Dhaval K.

Publication type:

Article

Systemic Bioequivalence Is Unlikely to Equal Target Site Bioequivalence for Nanotechnology Oncologic Products.

Published in:

AAPS Journal, 2019, v. 21, n. 2, p. 1, doi. 10.1208/s12248-019-0296-z

By:

Au, Jessie L.-S.;
Lu, Ze;
Abbiati, Roberto A.;
Wientjes, M. Guillaume

Publication type:

Article

Quantitative Prediction of Human Hepatic Clearance for P450 and Non-P450 Substrates from In Vivo Monkey Pharmacokinetics Study and In Vitro Metabolic Stability Tests Using Hepatocytes.

Published in:

AAPS Journal, 2019, v. 21, n. 2, p. 1, doi. 10.1208/s12248-019-0294-1

By:

Nishimuta, Haruka;
Watanabe, Takao;
Bando, Kiyoko

Publication type:

Article

Incurred Sample Reanalysis: Time to Change the Sample Size Calculation?

Published in:

AAPS Journal, 2019, v. 21, n. 2, p. 1, doi. 10.1208/s12248-019-0293-2

By:

Rudzki, Piotr J.;
Biecek, Przemysław;
Kaza, Michał

Publication type:

Article

Multiplexed Gene Expression as a Characterization of Bioactivity for Interferon Beta (IFN-β) Biosimilar Candidates: Impact of Innate Immune Response Modulating Impurities (IIRMIs).

Published in:

AAPS Journal, 2019, v. 21, n. 2, p. 1, doi. 10.1208/s12248-019-0300-7

By:

Mufarrege, Eduardo F.;
Haile, Lydia A.;
Etcheverrigaray, Marina;
Verthelyi, Daniela I.

Publication type:

Article

Dissolution and Translational Modeling Strategies Toward Establishing an In Vitro-In Vivo Link—a Workshop Summary Report.

Published in:

AAPS Journal, 2019, v. 21, n. 2, p. 1, doi. 10.1208/s12248-019-0298-x

By:

Heimbach, Tycho;
Suarez-Sharp, Sandra;
Kakhi, Maziar;
Holmstock, Nico;
Olivares-Morales, Andrés;
Pepin, Xavier;
Sjögren, Erik;
Tsakalozou, Eleftheria;
Seo, Paul;
Li, Min;
Zhang, Xinyuan;
Lin, Ho-Pi;
Montague, Timothy;
Mitra, Amitava;
Morris, Denise;
Patel, Nikunjkumar;
Kesisoglou, Filippos

Publication type:

Article

Predicting Overall Survival and Progression-Free Survival Using Tumor Dynamics in Advanced Breast Cancer Patients.

Published in:

AAPS Journal, 2019, v. 21, n. 2, p. 1, doi. 10.1208/s12248-018-0290-x

By:

Lim, Hyeong-Seok;
Sun, Wan;
Parivar, Kourosh;
Wang, Diane

Publication type:

Article

Tumor-Targeted Chemoimmunotherapy with Immune-Checkpoint Blockade for Enhanced Anti-Melanoma Efficacy.

Published in:

AAPS Journal, 2019, v. 21, n. 2, p. 1, doi. 10.1208/s12248-018-0289-3

By:

Li, Man;
Yang, Yuting;
Xu, Chaoqun;
Wei, Jiaojie;
Liu, Yingke;
Cun, Xingli;
Yu, Qianwen;
Tang, Xian;
Yin, Sheng;
Zhang, Zhirong;
He, Qin

Publication type:

Article

Dissolution Testing in Drug Product Development: Workshop Summary Report.

Published in:

AAPS Journal, 2019, v. 21, n. 2, p. 1, doi. 10.1208/s12248-018-0288-4

By:

Abend, Andreas;
Curran, David;
Kuiper, Jesse;
Lu, Xujin;
Li, Hanlin;
Hermans, Andre;
Kotwal, Pramod;
Diaz, Dorys A.;
Cohen, Michael J.;
Zhang, Limin;
Stippler, Erika;
Drazer, German;
Lin, Yiqing;
Raines, Kimberly;
Yu, Lawrence;
Coutant, Carrie A.;
Grady, Haiyan;
Krämer, Johannes;
Pope-Miksinski, Sarah;
Suarez-Sharp, Sandra

Publication type:

Article

What Does it Take to Make Model-Informed Precision Dosing Common Practice? Report from the 1st Asian Symposium on Precision Dosing.

Published in:

AAPS Journal, 2019, v. 21, n. 2, p. 1, doi. 10.1208/s12248-018-0286-6

By:

Polasek, Thomas M.;
Rostami-Hodjegan, Amin;
Yim, Dong-Seok;
Jamei, Masoud;
Lee, Howard;
Kimko, Holly;
Kim, Jae Kyoung;
Nguyen, Phuong Thi Thu;
Darwich, Adam S.;
Shin, Jae-Gook

Publication type:

Article

Evaluation of a Particulate Breast Cancer Vaccine Delivered via Skin.

Published in:

AAPS Journal, 2019, v. 21, n. 2, p. 1, doi. 10.1208/s12248-018-0285-7

By:

Chablani, Lipika;
Tawde, Suprita A.;
Akalkotkar, Archana;
D'Souza, Martin J.

Publication type:

Article

Survival Prolongation Index as a Novel Metric to Assess Anti-Tumor Activity in Xenograft Models.

Published in:

AAPS Journal, 2019, v. 21, n. 2, p. 1, doi. 10.1208/s12248-018-0284-8

By:

Chandra, Fiona;
Zaks, Lihi;
Zhu, Andy

Publication type:

Article

Scientific Considerations for the Review and Approval of First Generic Mometasone Furoate Nasal Suspension Spray in the United States from the Bioequivalence Perspective.

Published in:

AAPS Journal, 2019, v. 21, n. 2, p. 1, doi. 10.1208/s12248-018-0283-9

By:

Liu, Qing;
Absar, Mohammad;
Saluja, Bhawana;
Guo, Changning;
Chowdhury, Badrul;
Lionberger, Robert;
Conner, Dale P.;
Li, Bing V.

Publication type:

Article

Development of a New Inhaler for High-Efficiency Dispersion of Spray-Dried Powders Using Computational Fluid Dynamics (CFD) Modeling.

Published in:

AAPS Journal, 2019, v. 21, n. 2, p. 1, doi. 10.1208/s12248-018-0281-y

By:

Longest, Worth;
Farkas, Dale

Publication type:

Article

Cellular Uptake of MCT1 Inhibitors AR-C155858 and AZD3965 and Their Effects on MCT-Mediated Transport of L-Lactate in Murine 4T1 Breast Tumor Cancer Cells.

Published in:

AAPS Journal, 2019, v. 21, n. 2, p. 1, doi. 10.1208/s12248-018-0279-5

By:

Guan, Xiaowen;
Rodriguez-Cruz, Vivian;
Morris, Marilyn E.

Publication type:

Article

Sorafenib N-Oxide Is an Inhibitor of Human Hepatic CYP3A4.

Published in:

AAPS Journal, 2019, v. 21, n. 2, p. 1, doi. 10.1208/s12248-018-0262-1

By:

Ghassabian, Sussan;
Gillani, Tina B.;
Rawling, Tristan;
Crettol, Severine;
Nair, Pramod C.;
Murray, Michael

Publication type:

Article