Works matching IS 15507416 AND DT 2017 AND VI 19 AND IP 3

Results: 30

Application of Pharmacokinetics and Pharmacodynamics in Product Life Cycle Management. A Case Study with a Carbidopa-Levodopa Extended-Release Formulation.

Published in:

AAPS Journal, 2017, v. 19, n. 3, p. 607, doi. 10.1208/s12248-016-0032-x

By:

Modi, Nishit

Publication type:

Article

Inclusion of Digestible Surfactants in Solid SMEDDS Formulation Removes Lag Time and Influences the Formation of Structured Particles During Digestion.

Published in:

AAPS Journal, 2017, v. 19, n. 3, p. 754, doi. 10.1208/s12248-016-0036-6

By:

Vithani, Kapilkumar;
Hawley, Adrian;
Jannin, Vincent;
Pouton, Colin;
Boyd, Ben

Publication type:

Article

Identifying Metabolites of Meclonazepam by High-Resolution Mass Spectrometry Using Human Liver Microsomes, Hepatocytes, a Mouse Model, and Authentic Urine Samples.

Published in:

AAPS Journal, 2017, v. 19, n. 3, p. 736, doi. 10.1208/s12248-016-0040-x

By:

Vikingsson, Svante;
Wohlfarth, Ariane;
Andersson, Mikael;
Gréen, Henrik;
Roman, Markus;
Josefsson, Martin;
Kugelberg, Fredrik;
Kronstrand, Robert

Publication type:

Article

Population Pharmacokinetic-Pharmacodynamic Model of Oral Fludrocortisone and Intravenous Hydrocortisone in Healthy Volunteers.

Published in:

AAPS Journal, 2017, v. 19, n. 3, p. 727, doi. 10.1208/s12248-016-0041-9

By:

Hamitouche, Noureddine;
Comets, Emmanuelle;
Ribot, Mégane;
Alvarez, Jean-Claude;
Bellissant, Eric;
Laviolle, Bruno

Publication type:

Article

Pharmacokinetics of the Inhaled Selective Glucocorticoid Receptor Modulator AZD5423 Following Inhalation Using Different Devices.

Published in:

AAPS Journal, 2017, v. 19, n. 3, p. 865, doi. 10.1208/s12248-016-0042-8

By:

Melin, Johanna;
Prothon, Susanne;
Kloft, Charlotte;
Cleton, Adriaan;
Amilon, Carl;
Jorup, Carin;
Bäckman, Per;
Olsson, Bo;
Hamrén, Ulrika

Publication type:

Article

Radiomitigation and Tissue Repair Activity of Systemically Administered Therapeutic Peptide TP508 Is Enhanced by PEGylation.

Published in:

AAPS Journal, 2017, v. 19, n. 3, p. 743, doi. 10.1208/s12248-016-0043-7

By:

McVicar, Scott;
Rayavara, Kempaiah;
Carney, Darrell

Publication type:

Article

Scientific and Regulatory Considerations for Generic Complex Drug Products Containing Nanomaterials.

Published in:

AAPS Journal, 2017, v. 19, n. 3, p. 619, doi. 10.1208/s12248-017-0044-1

By:

Zheng, Nan;
Sun, Dajun;
Zou, Peng;
Jiang, Wenlei

Publication type:

Article

Colloidal Gels with Extracellular Matrix Particles and Growth Factors for Bone Regeneration in Critical Size Rat Calvarial Defects.

Published in:

AAPS Journal, 2017, v. 19, n. 3, p. 703, doi. 10.1208/s12248-017-0045-0

By:

Townsend, Jakob;
Dennis, S.;
Whitlow, Jonathan;
Feng, Yi;
Wang, Jinxi;
Andrews, Brian;
Nudo, Randolph;
Detamore, Michael;
Berkland, Cory

Publication type:

Article

A Heparin Purification Process Removes Spiked Transmissible Spongiform Encephalopathy Agent.

Published in:

AAPS Journal, 2017, v. 19, n. 3, p. 765, doi. 10.1208/s12248-017-0047-y

By:

Bett, Cyrus;
Grgac, Ksenija;
Long, Dianna;
Karfunkle, Michael;
Keire, David;
Asher, David;
Gregori, Luisa

Publication type:

Article

Liposomal Drug Product Development and Quality: Current US Experience and Perspective.

Published in:

AAPS Journal, 2017, v. 19, n. 3, p. 632, doi. 10.1208/s12248-017-0049-9

By:

Kapoor, Mamta;
Lee, Sau;
Tyner, Katherine

Publication type:

Article

Reliable Rate Measurements for Active and Passive Hepatic Uptake Using Plated Human Hepatocytes.

Published in:

AAPS Journal, 2017, v. 19, n. 3, p. 787, doi. 10.1208/s12248-017-0051-2

By:

Bi, Yi-an;
Scialis, Renato;
Lazzaro, Sarah;
Mathialagan, Sumathy;
Kimoto, Emi;
Keefer, Julie;
Zhang, Hui;
Vildhede, Anna;
Costales, Chester;
Rodrigues, A.;
Tremaine, Larry;
Varma, Manthena

Publication type:

Article

Advantageous Solubility-Permeability Interplay When Using Amorphous Solid Dispersion (ASD) Formulation for the BCS Class IV P-gp Substrate Rifaximin: Simultaneous Increase of Both the Solubility and the Permeability.

Published in:

AAPS Journal, 2017, v. 19, n. 3, p. 806, doi. 10.1208/s12248-017-0052-1

By:

Beig, Avital;
Fine-Shamir, Noa;
Lindley, David;
Miller, Jonathan;
Dahan, Arik

Publication type:

Article

Phloretin Prevents High-Fat Diet-Induced Obesity and Improves Metabolic Homeostasis.

Published in:

AAPS Journal, 2017, v. 19, n. 3, p. 797, doi. 10.1208/s12248-017-0053-0

By:

Alsanea, Sary;
Gao, Mingming;
Liu, Dexi

Publication type:

Article

Challenges and Future Prospects for the Delivery of Biologics: Oral Mucosal, Pulmonary, and Transdermal Routes.

Published in:

AAPS Journal, 2017, v. 19, n. 3, p. 652, doi. 10.1208/s12248-017-0054-z

By:

Morales, Javier;
Fathe, Kristin;
Brunaugh, Ashlee;
Ferrati, Silvia;
Li, Song;
Montenegro-Nicolini, Miguel;
Mousavikhamene, Zeynab;
McConville, Jason;
Prausnitz, Mark;
Smyth, Hugh

Publication type:

Article

Exploring Canine-Human Differences in Product Performance. Part II: Use of Modeling and Simulation to Explore the Impact of Formulation on Ciprofloxacin In Vivo Absorption and Dissolution in Dogs.

Published in:

AAPS Journal, 2017, v. 19, n. 3, p. 712, doi. 10.1208/s12248-017-0055-y

By:

Martinez, M.;
Mistry, B.;
Lukacova, V.;
Lentz, K.;
Polli, J.;
Hoag, S.;
Dowling, T.;
Kona, R.;
Fahmy, R.

Publication type:

Article

Assessment of Correlation Between Early and Late Efficacy Endpoints to Identify Potential Surrogacy Relationships in Non-Hodgkin Lymphoma: a Literature-Based Meta-analysis of 108 Phase II and Phase III Studies.

Published in:

AAPS Journal, 2017, v. 19, n. 3, p. 669, doi. 10.1208/s12248-017-0056-x

By:

Zhu, Rui;
Lu, Dan;
Chu, Yu-Waye;
Chai, Akiko;
Green, Michelle;
Zhang, Nancy;
Jin, Jin

Publication type:

Article

Aptamer-Conjugated Chitosan-Anchored Liposomal Complexes for Targeted Delivery of Erlotinib to EGFR-Mutated Lung Cancer Cells.

Published in:

AAPS Journal, 2017, v. 19, n. 3, p. 814, doi. 10.1208/s12248-017-0057-9

By:

Li, Fengqiao;
Mei, Hao;
Xie, Xiaodong;
Zhang, Huijuan;
Liu, Jian;
Lv, Tingting;
Nie, Huifang;
Gao, Yu;
Jia, Lee

Publication type:

Article

Modeling a Composite Score in Parkinson's Disease Using Item Response Theory.

Published in:

AAPS Journal, 2017, v. 19, n. 3, p. 837, doi. 10.1208/s12248-017-0058-8

By:

Gottipati, Gopichand;
Karlsson, Mats;
Plan, Elodie

Publication type:

Article

A Proposal to Redefine Clinical Immunogenicity Assessment.

Published in:

AAPS Journal, 2017, v. 19, n. 3, p. 599, doi. 10.1208/s12248-017-0059-7

By:

Mytych, Daniel;
Hock, M.;
Kroenke, Mark;
Jawa, Vibha;
Kaliyaperumal, Arunan;
Zhou, Yanchen

Publication type:

Article

Characterising Drug Release from Immediate-Release Formulations of a Poorly Soluble Compound, Basmisanil, Through Absorption Modelling and Dissolution Testing.

Published in:

AAPS Journal, 2017, v. 19, n. 3, p. 827, doi. 10.1208/s12248-017-0060-1

By:

Stillhart, Cordula;
Parrott, Neil;
Lindenberg, Marc;
Chalus, Pascal;
Bentley, Darren;
Szepes, Anikó

Publication type:

Article

Erratum to: Reliable Rate Measurements for Active and Passive Hepatic Uptake Using Plated Human Hepatocytes.

Published in:

2017

By:

Bi, Yi-an;
Scialis, Renato;
Lazzaro, Sarah;
Mathialagan, Sumathy;
Kimoto, Emi;
Keefer, Julie;
Zhang, Hui;
Vildhede, Anna;
Costales, Chester;
Rodrigues, A.;
Tremaine, Larry;
Varma, Manthena

Publication type:

Erratum

A LC-MS All-in-One Workflow for Site-Specific Location, Identification and Quantification of N-/O- Glycosylation in Human Chorionic Gonadotropin Drug Products.

Published in:

AAPS Journal, 2017, v. 19, n. 3, p. 846, doi. 10.1208/s12248-017-0062-z

By:

Zhu, Hongbin;
Qiu, Chen;
Ruth, Ashley;
Keire, David;
Ye, Hongping

Publication type:

Article

Development Considerations for Nanocrystal Drug Products.

Published in:

AAPS Journal, 2017, v. 19, n. 3, p. 642, doi. 10.1208/s12248-017-0064-x

By:

Chen, Mei-Ling;
John, Mathew;
Lee, Sau;
Tyner, Katherine

Publication type:

Article

Structure-Promiscuity Relationship Puzzles-Extensively Assayed Analogs with Large Differences in Target Annotations.

Published in:

AAPS Journal, 2017, v. 19, n. 3, p. 856, doi. 10.1208/s12248-017-0066-8

By:

Hu, Ye;
Jasial, Swarit;
Gilberg, Erik;
Bajorath, Jürgen

Publication type:

Article

Current Trends in Ligand Binding Real-Time Measurement Technologies.

Published in:

AAPS Journal, 2017, v. 19, n. 3, p. 682, doi. 10.1208/s12248-017-0067-7

By:

Fraser, Stephanie;
Shih, Judy Y.;
Ware, Mark;
O'Connor, Edward;
Cameron, Mark;
Schwickart, Martin;
Zhao, Xuemei;
Regnstrom, Karin

Publication type:

Article

Global Harmonization of Comparator Products for Bioequivalence Studies.

Published in:

AAPS Journal, 2017, v. 19, n. 3, p. 603, doi. 10.1208/s12248-017-0068-6

By:

Gwaza, Luther;
Gordon, John;
Leufkens, Hubert;
Stahl, Matthias;
García-Arieta, Alfredo

Publication type:

Article

Evaluation of the Potency, Neutralizing Antibody Response, and Stability of a Recombinant Fusion Protein Vaccine for Streptococcus pyogenes.

Published in:

AAPS Journal, 2017, v. 19, n. 3, p. 875, doi. 10.1208/s12248-017-0069-5

By:

Burlet, E.;
HogenEsch, H.;
Dunham, A.;
Morefield, G.

Publication type:

Article

Spray-Dried Thiolated Chitosan-Coated Sodium Alginate Multilayer Microparticles for Vaginal HIV Microbicide Delivery.

Published in:

AAPS Journal, 2017, v. 19, n. 3, p. 692, doi. 10.1208/s12248-016-0007-y

By:

Meng, Jianing;
Agrahari, Vivek;
Ezoulin, Miezan;
Purohit, Sudhaunshu;
Zhang, Tao;
Molteni, Agostino;
Dim, Daniel;
Oyler, Nathan;
Youan, Bi-Botti

Publication type:

Article

Erratum to: Systematic Verification of Bioanalytical Similarity Between a Biosimilar and a Reference Biotherapeutic: Committee Recommendations for the Development and Validation of a Single Ligand-Binding Assay to Support Pharmacokinetic Assessments.

Published in:

2017

By:

Marini, Joseph;
Anderson, Michael;
Cai, Xiao-Yan;
Chappell, John;
Coffey, Todd;
Gouty, Dominique;
Kasinath, Aparna;
Koppenburg, Vera;
Oldfield, Philip;
Rebarchak, Shannon;
Bowsher, Ronald

Publication type:

Erratum

Pharmacokinetic Steady-States Highlight Interesting Target-Mediated Disposition Properties.

Published in:

AAPS Journal, 2017, v. 19, n. 3, p. 772, doi. 10.1208/s12248-016-0031-y

By:

Gabrielsson, Johan;
Peletier, Lambertus

Publication type:

Article