Works matching IS 15507416 AND DT 2017 AND VI 19 AND IP 2

Results: 30

Tissue Concentration of Dodecafluoropentane (DDFP) Following Repeated IV Administration in the New Zealand White Rabbit.

Published in:

AAPS Journal, 2017, v. 19, n. 2, p. 520, doi. 10.1208/s12248-016-0013-0

By:

Arthur, Christine;
Song, Lin;
Culp, William;
Brown, Aliza;
Borrelli, Michael;
Skinner, Robert;
Hendrickson, Howard

Publication type:

Article

Current Update of a Carboxymethylcellulose-PEG Conjugate Platform for Delivery of Insoluble Cytotoxic Agents to Tumors.

Published in:

AAPS Journal, 2017, v. 19, n. 2, p. 386, doi. 10.1208/s12248-016-0014-z

By:

Yang, Yang;
Bteich, Joseph;
Li, Shyh-Dar

Publication type:

Article

Delivery of Small Interfering RNA to Inhibit Vascular Endothelial Growth Factor in Zebrafish Using Natural Brain Endothelia Cell-Secreted Exosome Nanovesicles for the Treatment of Brain Cancer.

Published in:

AAPS Journal, 2017, v. 19, n. 2, p. 475, doi. 10.1208/s12248-016-0015-y

By:

Yang, Tianzhi;
Fogarty, Brittany;
LaForge, Bret;
Aziz, Salma;
Pham, Thuy;
Lai, Leanne;
Bai, Shuhua

Publication type:

Article

Epigenetic CpG Methylation of the Promoter and Reactivation of the Expression of GSTP1 by Astaxanthin in Human Prostate LNCaP Cells.

Published in:

AAPS Journal, 2017, v. 19, n. 2, p. 421, doi. 10.1208/s12248-016-0016-x

By:

Yang, Yuqing;
Fuentes, Francisco;
Shu, Limin;
Wang, Chao;
Pung, Doug;
Li, Wenji;
Zhang, Chengyue;
Guo, Yue;
Kong, Ah-Ng

Publication type:

Article

Use of Spray-Dried Dispersions in Early Pharmaceutical Development: Theoretical and Practical Challenges.

Published in:

AAPS Journal, 2017, v. 19, n. 2, p. 321, doi. 10.1208/s12248-016-0017-9

By:

Li, Jinjiang;
Patel, Dhaval;
Wang, George

Publication type:

Article

Validation of a Drug-Resistant Anti-Adalimumab Antibody Assay to Monitor Immunogenicity in the Presence of High Concentrations of Adalimumab.

Published in:

AAPS Journal, 2017, v. 19, n. 2, p. 468, doi. 10.1208/s12248-016-0018-8

By:

Bian, Sumin;
Ferrante, Marc;
Gils, Ann

Publication type:

Article

Metabolic Profiling of Human Long-Term Liver Models and Hepatic Clearance Predictions from In Vitro Data Using Nonlinear Mixed-Effects Modeling.

Published in:

AAPS Journal, 2017, v. 19, n. 2, p. 534, doi. 10.1208/s12248-016-0019-7

By:

Kratochwil, Nicole;
Meille, Christophe;
Fowler, Stephen;
Klammers, Florian;
Ekiciler, Aynur;
Molitor, Birgit;
Simon, Sandrine;
Walter, Isabelle;
McGinnis, Claudia;
Walther, Johanna;
Leonard, Brian;
Triyatni, Miriam;
Javanbakht, Hassan;
Funk, Christoph;
Schuler, Franz;
Lavé, Thierry;
Parrott, Neil

Publication type:

Article

Utility of Microdialysis in Infectious Disease Drug Development and Dose Optimization.

Published in:

AAPS Journal, 2017, v. 19, n. 2, p. 334, doi. 10.1208/s12248-016-0020-1

By:

Deitchman, Amelia;
Heinrichs, M.;
Khaowroongrueng, Vipada;
Jadhav, Satyawan;
Derendorf, Hartmut

Publication type:

Article

A Model for Predicting the Interindividual Variability of Drug-Drug Interactions.

Published in:

AAPS Journal, 2017, v. 19, n. 2, p. 497, doi. 10.1208/s12248-016-0021-0

By:

Tod, M.;
Bourguignon, L.;
Bleyzac, N.;
Goutelle, S.

Publication type:

Article

Pharmacokinetics and Saturable Absorption of Gabapentin in Nursing Home Elderly Patients.

Published in:

AAPS Journal, 2017, v. 19, n. 2, p. 551, doi. 10.1208/s12248-016-0022-z

By:

Ahmed, Ghada;
Bathena, Sai;
Brundage, Richard;
Leppik, Ilo;
Conway, Jeannine;
Schwartz, Janice;
Birnbaum, Angela

Publication type:

Article

Cardiovascular Ion Channel Inhibitor Drug-Drug Interactions with P-glycoprotein.

Published in:

AAPS Journal, 2017, v. 19, n. 2, p. 409, doi. 10.1208/s12248-016-0023-y

By:

Ledwitch, Kaitlyn;
Roberts, Arthur

Publication type:

Article

GDF11 Treatment Attenuates the Recovery of Skeletal Muscle Function After Injury in Older Rats.

Published in:

AAPS Journal, 2017, v. 19, n. 2, p. 431, doi. 10.1208/s12248-016-0024-x

By:

Zhou, Yu;
Sharma, Neel;
Dukes, David;
Myzithras, Maria;
Gupta, Priyanka;
Khalil, Ashraf;
Kahn, Julius;
Ahlberg, Jennifer;
Hayes, David;
Franti, Michael;
Criswell, Tracy

Publication type:

Article

Bioavailability and Bioequivalence Aspects of Oral Modified-Release Drug Products.

Published in:

AAPS Journal, 2017, v. 19, n. 2, p. 360, doi. 10.1208/s12248-016-0025-9

By:

Wang, Rong;
Conner, Dale;
Li, Bing

Publication type:

Article

Immune Suppression During Preclinical Drug Development Mitigates Immunogenicity-Mediated Impact on Therapeutic Exposure.

Published in:

AAPS Journal, 2017, v. 19, n. 2, p. 447, doi. 10.1208/s12248-016-0026-8

By:

Herskovitz, Jonathan;
Ryman, Josiah;
Thway, Theingi;
Lee, Stephanie;
Zhou, Lei;
Chirmule, Narendra;
Meibohm, Bernd;
Jawa, Vibha

Publication type:

Article

Microdialysis Monitoring in Clinical Traumatic Brain Injury and Its Role in Neuroprotective Drug Development.

Published in:

AAPS Journal, 2017, v. 19, n. 2, p. 367, doi. 10.1208/s12248-016-0027-7

By:

Thelin, Eric;
Carpenter, Keri;
Hutchinson, Peter;
Helmy, Adel

Publication type:

Article

Insulin Formulation Characterization-the Thioflavin T Assays.

Published in:

AAPS Journal, 2017, v. 19, n. 2, p. 397, doi. 10.1208/s12248-016-0028-6

By:

Schlein, Morten

Publication type:

Article

Exposure-Response and Tumor Growth Inhibition Analyses of the Monovalent Anti-c-MET Antibody Onartuzumab (MetMAb) in the Second- and Third-Line Non-Small Cell Lung Cancer.

Published in:

AAPS Journal, 2017, v. 19, n. 2, p. 527, doi. 10.1208/s12248-016-0029-5

By:

Han, Kelong;
Chanu, Pascal;
Jonsson, Fredrik;
Winter, Helen;
Bruno, René;
Jin, Jin;
Stroh, Mark

Publication type:

Article

Approaches to Mitigate the Unwanted Immunogenicity of Therapeutic Proteins during Drug Development.

Published in:

AAPS Journal, 2017, v. 19, n. 2, p. 377, doi. 10.1208/s12248-016-0030-z

By:

Salazar-Fontana, Laura;
Desai, Dharmesh;
Khan, Tarik;
Pillutla, Renuka;
Prior, Sandra;
Ramakrishnan, Radha;
Schneider, Jennifer;
Joseph, Alexandra

Publication type:

Article

An Integrated Assessment of the Effects of Immunogenicity on the Pharmacokinetics, Safety, and Efficacy of Elotuzumab.

Published in:

AAPS Journal, 2017, v. 19, n. 2, p. 557, doi. 10.1208/s12248-016-0033-9

By:

Passey, Chaitali;
Mora, Johanna;
Dodge, Robert;
Gibiansky, Leonid;
Sheng, Jennifer;
Roy, Amit;
Bello, Akintunde;
Gupta, Manish

Publication type:

Article

A Comparative Study of the Bone Regenerative Effect of Chemically Modified RNA Encoding BMP-2 or BMP-9.

Published in:

AAPS Journal, 2017, v. 19, n. 2, p. 438, doi. 10.1208/s12248-016-0034-8

By:

Khorsand, Behnoush;
Elangovan, Satheesh;
Hong, Liu;
Dewerth, Alexander;
Kormann, Michael;
Salem, Aliasger

Publication type:

Article

Erratum to: Tumor Static Concentration Curves in Combination Therapy.

Published in:

2017

By:

Cardilin, Tim;
Almquist, Joachim;
Jirstand, Mats;
Soselly, Alexandre;
Amendt, Christiane;
Bawab, Samer;
Gabrielsson, Johan

Publication type:

Erratum

Identification of New Synthetic Cannabinoid ADB-CHMINACA (MAB-CHMINACA) Metabolites in Human Hepatocytes.

Published in:

AAPS Journal, 2017, v. 19, n. 2, p. 568, doi. 10.1208/s12248-016-0037-5

By:

Carlier, Jeremy;
Diao, Xingxing;
Sempio, Cristina;
Huestis, Marilyn

Publication type:

Article

Influence of drug load and physical form of cinnarizine in new SNEDDS dosing regimens: in vivo and in vitro evaluations.

Published in:

AAPS Journal, 2017, v. 19, n. 2, p. 587, doi. 10.1208/s12248-016-0038-4

By:

Siqueira, Scheyla;
Müllertz, Anette;
Gräeser, Kirsten;
Kasten, Georgia;
Mu, Huiling;
Rades, Thomas

Publication type:

Article

Porous mannitol carrier for pulmonary delivery of cyclosporine A nanoparticles.

Published in:

AAPS Journal, 2017, v. 19, n. 2, p. 578, doi. 10.1208/s12248-016-0039-3

By:

Leung, Sharon;
Wong, Jennifer;
Guerra, Heloisa;
Samnick, Kevin;
Prud'homme, Robert;
Chan, Hak-Kim

Publication type:

Article

Optimal Affinity of a Monoclonal Antibody: Guiding Principles Using Mechanistic Modeling.

Published in:

AAPS Journal, 2017, v. 19, n. 2, p. 510, doi. 10.1208/s12248-016-0004-1

By:

Tiwari, Abhinav;
Abraham, Anson;
Harrold, John;
Zutshi, Anup;
Singh, Pratap

Publication type:

Article

Erratum to: Optimal Affinity of a Monoclonal Antibody: Guiding Principles Using Mechanistic Modeling.

Published in:

2017

By:

Tiwari, Abhinav;
Abraham, Anson;
Harrold, John;
Zutshi, Anup;
Singh, Pratap

Publication type:

Erratum

Population Pharmacokinetics of an Extended-Release Formulation of Exenatide Following Single- and Multiple-Dose Administration.

Published in:

AAPS Journal, 2017, v. 19, n. 2, p. 487, doi. 10.1208/s12248-016-9975-1

By:

Cirincione, Brenda;
Edwards, Jeffrey;
Mager, Donald

Publication type:

Article

Tumor Static Concentration Curves in Combination Therapy.

Published in:

AAPS Journal, 2017, v. 19, n. 2, p. 456, doi. 10.1208/s12248-016-9991-1

By:

Cardilin, Tim;
Almquist, Joachim;
Jirstrand, Mats;
Sostelly, Alexandre;
Amendt, Christiane;
Bawab, Samer;
Gabrielsson, Johan

Publication type:

Article

Clinical Translation of the National Institutes of Health's Investments in Nanodrug Products and Devices.

Published in:

AAPS Journal, 2017, v. 19, n. 2, p. 343, doi. 10.1208/s12248-016-9995-x

By:

Henderson, Lori;
Shankar, Lalitha

Publication type:

Article

Erratum to: Intra-articular Injection of Urinary Bladder Matrix Reduces Osteoarthritis Development.

Published in:

2017

By:

Jacobs, Heather;
Rathod, Sona;
Wolf, Matthew;
Elisseeff, Jennifer

Publication type:

Erratum