Works matching IS 15507416 AND DT 2017 AND VI 19 AND IP 1

Results: 30

Physiologically Based Pharmacokinetic (PBPK) Modeling of Pharmaceutical Nanoparticles.

Published in:

AAPS Journal, 2017, v. 19, n. 1, p. 26, doi. 10.1208/s12248-016-0010-3

By:

Li, Min;
Zou, Peng;
Tyner, Katherine;
Lee, Sau

Publication type:

Article

Mitigation of Pre-existing Antibodies to a Biotherapeutic in Non-clinical Species When Establishing Anti-drug Antibody Assay Cutpoint.

Published in:

AAPS Journal, 2017, v. 19, n. 1, p. 313, doi. 10.1208/s12248-016-0011-2

By:

Kumar, Seema;
DelCarpini, Jason;
Qu, Qiang;
Kane, Martin;
Gorovits, Boris

Publication type:

Article

Revealing the Neuroendocrine Response After Remoxipride Treatment Using Multi-Biomarker Discovery and Quantifying It by PK/PD Modeling.

Published in:

AAPS Journal, 2017, v. 19, n. 1, p. 274, doi. 10.1208/s12248-016-0002-3

By:

Brink, Willem;
Wong, Yin;
Gülave, Berfin;
Graaf, Piet;
Lange, Elizatbeth

Publication type:

Article

Bringing Curcumin to the Clinic in Cancer Prevention: a Review of Strategies to Enhance Bioavailability and Efficacy.

Published in:

AAPS Journal, 2017, v. 19, n. 1, p. 54, doi. 10.1208/s12248-016-0003-2

By:

Mahran, Rama;
Hagras, Magda;
Sun, Duxin;
Brenner, Dean

Publication type:

Article

Accelerating Regulated Bioanalysis for Biotherapeutics: Case Examples Using a Microfluidic Ligand Binding Assay Platform.

Published in:

AAPS Journal, 2017, v. 19, n. 1, p. 82, doi. 10.1208/s12248-016-0006-z

By:

Liu, Rong;
Hoffpauir, Brian;
Chilewski, Shannon;
Gamberdella, Janice;
Kavita, Uma;
Duo, Jia;
Gleason, Carol;
Zhang, Yan;
Pillutla, Renuka;
DeSilva, Binodh;
Hamuro, Lora

Publication type:

Article

Nanomaterial Drug Products: Manufacturing and Analytical Perspectives.

Published in:

AAPS Journal, 2017, v. 19, n. 1, p. 18, doi. 10.1208/s12248-016-0008-x

By:

Sayes, Christie;
Aquino, Grace;
Hickey, Anthony

Publication type:

Article

Clarithromycin, Midazolam, and Digoxin: Application of PBPK Modeling to Gain New Insights into Drug-Drug Interactions and Co-medication Regimens.

Published in:

AAPS Journal, 2017, v. 19, n. 1, p. 298, doi. 10.1208/s12248-016-0009-9

By:

Moj, Daniel;
Hanke, Nina;
Britz, Hannah;
Frechen, Sebastian;
Kanacher, Tobias;
Wendl, Thomas;
Haefeli, Walter;
Lehr, Thorsten

Publication type:

Article

Development of a Flow-Through USP-4 Apparatus Drug Release Assay to Evaluate Doxorubicin Liposomes.

Published in:

AAPS Journal, 2017, v. 19, n. 1, p. 150, doi. 10.1208/s12248-016-9958-2

By:

Yuan, Wenmin;
Kuai, Rui;
Dai, Zhipeng;
Yuan, Yue;
Zheng, Nan;
Jiang, Wenlei;
Noble, Charles;
Hayes, Mark;
Szoka, Francis;
Schwendeman, Anna

Publication type:

Article

The Selection and Control of Starting Materials Should be Governed by Science and Risk-Based Approaches.

Published in:

AAPS Journal, 2017, v. 19, n. 1, p. 1, doi. 10.1208/s12248-016-9960-8

By:

Watson, Timothy;
Nosal, Roger;
Lepore, John;
Montgomery, Frank

Publication type:

Article

Statistical Approaches to Assess Biosimilarity from Analytical Data.

Published in:

AAPS Journal, 2017, v. 19, n. 1, p. 4, doi. 10.1208/s12248-016-9968-0

By:

Burdick, Richard;
Coffey, Todd;
Gutka, Hiten;
Gratzl, Gyöngyi;
Conlon, Hugh;
Huang, Chi-Ting;
Boyne, Michael;
Kuehne, Henriette

Publication type:

Article

Application of Item Response Theory to Modeling of Expanded Disability Status Scale in Multiple Sclerosis.

Published in:

AAPS Journal, 2017, v. 19, n. 1, p. 172, doi. 10.1208/s12248-016-9977-z

By:

Novakovic, A.;
Krekels, E.;
Munafo, A.;
Ueckert, S.;
Karlsson, M.

Publication type:

Article

The Effect of Polymorphism on Surface Energetics of D-Mannitol Polymorphs.

Published in:

AAPS Journal, 2017, v. 19, n. 1, p. 103, doi. 10.1208/s12248-016-9978-y

By:

Smith, Robert;
Shah, Umang;
Parambil, Jose;
Burnett, Daniel;
Thielmann, Frank;
Heng, Jerry

Publication type:

Article

Early Development Challenges for Drug Products Containing Nanomaterials.

Published in:

AAPS Journal, 2017, v. 19, n. 1, p. 92, doi. 10.1208/s12248-016-9980-4

By:

Grossman, Jennifer;
Crist, Rachael;
Clogston, Jeffrey

Publication type:

Article

Comparisons of Serum Infliximab and Antibodies-to-Infliximab Tests Used in Inflammatory Bowel Disease Clinical Trials of Remicade®.

Published in:

AAPS Journal, 2017, v. 19, n. 1, p. 161, doi. 10.1208/s12248-016-9981-3

By:

Marini, Joseph;
Sendecki, Jocelyn;
Cornillie, Freddy;
Popp, John;
Black, Shawn;
Blank, Marion;
Gils, Ann;
Van Stappen, Thomas;
Hamann, Dörte;
Rispens, Theo;
Thérien, Lina;
Chun, Kelly;
Shankar, Gopi

Publication type:

Article

Bone Regeneration Using Gene-Activated Matrices.

Published in:

AAPS Journal, 2017, v. 19, n. 1, p. 43, doi. 10.1208/s12248-016-9982-2

By:

D'Mello, Sheetal;
Atluri, Keerthi;
Geary, Sean;
Hong, Liu;
Elangovan, Satheesh;
Salem, Aliasger

Publication type:

Article

Particle Characterization for a Protein Drug Product Stored in Pre-Filled Syringes Using Micro-Flow Imaging, Archimedes, and Quartz Crystal Microbalance with Dissipation.

Published in:

AAPS Journal, 2017, v. 19, n. 1, p. 110, doi. 10.1208/s12248-016-9983-1

By:

Zheng, Songyan;
Puri, Aastha;
Li, Jinjiang;
Jaiswal, Archana;
Adams, Monica

Publication type:

Article

Mechanistic Evaluation of Hydration Effects on the Human Epidermal Permeation of Salicylate Esters.

Published in:

AAPS Journal, 2017, v. 19, n. 1, p. 180, doi. 10.1208/s12248-016-9984-0

By:

Yousef, Shereen;
Mohammed, Yousuf;
Namjoshi, Sarika;
Grice, Jeffrey;
Sakran, Wedad;
Roberts, Michael

Publication type:

Article

Role of HLA-DP in the Presentation of Epitopes from the Truncated Bacterial PE38 Immunotoxin.

Published in:

AAPS Journal, 2017, v. 19, n. 1, p. 117, doi. 10.1208/s12248-016-9986-y

By:

Mazor, Ronit;
Addissie, Selamawit;
Jang, Youjin;
Tai, Chin-Hsien;
Rose, Jeremy;
Hakim, Fran;
Pastan, Ira

Publication type:

Article

Commentary on 'Statistical Approaches to Assess Biosimilarity from Analytical Data' by Burdick et al.

Published in:

AAPS Journal, 2017, v. 19, n. 1, p. 15, doi. 10.1208/s12248-016-9987-x

By:

Tsong, Yi;
Xia, Qi;
Weng, Yu-Ting

Publication type:

Article

The Delivery of High-Dose Dry Powder Antibiotics by a Low-Cost Generic Inhaler.

Published in:

AAPS Journal, 2017, v. 19, n. 1, p. 191, doi. 10.1208/s12248-016-9988-9

By:

Parumasivam, Thaigarajan;
Leung, Sharon;
Tang, Patricia;
Mauro, Citterio;
Britton, Warwick;
Chan, Hak-Kim

Publication type:

Article

Magnitude of Increased Infliximab Clearance Imposed by Anti-infliximab Antibodies in Crohn's Disease Is Determined by Their Concentration.

Published in:

AAPS Journal, 2017, v. 19, n. 1, p. 223, doi. 10.1208/s12248-016-9989-8

By:

Edlund, Helena;
Steenholdt, Casper;
Ainsworth, Mark;
Goebgen, Eva;
Brynskov, Jørn;
Thomsen, Ole;
Huisinga, Wilhelm;
Kloft, Charlotte

Publication type:

Article

Relation of Transcriptional Factors to the Expression and Activity of Cytochrome P450 and UDP-Glucuronosyltransferases 1A in Human Liver: Co-Expression Network Analysis.

Published in:

AAPS Journal, 2017, v. 19, n. 1, p. 203, doi. 10.1208/s12248-016-9990-2

By:

Zhong, Shilong;
Han, Weichao;
Hou, Chuqi;
Liu, Junjin;
Wu, Lili;
Liu, Menghua;
Liang, Zhi;
Lin, Haoming;
Zhou, Lili;
Liu, Shuwen;
Tang, Lan

Publication type:

Article

Pharmacokinetic Modeling and Monte Carlo Simulation to Predict Interindividual Variability in Human Exposure to Oseltamivir and Its Active Metabolite, Ro 64-0802.

Published in:

AAPS Journal, 2017, v. 19, n. 1, p. 286, doi. 10.1208/s12248-016-9992-0

By:

Ito, Mototsugu;
Kusuhara, Hiroyuki;
Ose, Atsushi;
Kondo, Tsunenori;
Tanabe, Kazunari;
Nakayama, Hideki;
Horita, Shigeru;
Fujita, Takuya;
Sugiyama, Yuichi

Publication type:

Article

Development and Translational Application of an Integrated, Mechanistic Model of Antibody-Drug Conjugate Pharmacokinetics.

Published in:

AAPS Journal, 2017, v. 19, n. 1, p. 130, doi. 10.1208/s12248-016-9993-z

By:

Sukumaran, Siddharth;
Zhang, Crystal;
Leipold, Douglas;
Saad, Ola;
Xu, Keyang;
Gadkar, Kapil;
Samineni, Divya;
Wang, Bei;
Milojic-Blair, Marija;
Carrasco-Triguero, Montserrat;
Rubinfeld, Bonnee;
Fielder, Paul;
Lin, Kedan;
Ramanujan, Saroja

Publication type:

Article

Pharmacokinetic Dashboard-Recommended Dosing Is Different than Standard of Care Dosing in Infliximab-Treated Pediatric IBD Patients.

Published in:

AAPS Journal, 2017, v. 19, n. 1, p. 215, doi. 10.1208/s12248-016-9994-y

By:

Dubinsky, Marla;
Phan, Becky;
Singh, Namita;
Rabizadeh, Shervin;
Mould, Diane

Publication type:

Article

Development of a Non-Aqueous Dispersion to Improve Intestinal Epithelial Flux of Poorly Permeable Macromolecules.

Published in:

AAPS Journal, 2017, v. 19, n. 1, p. 244, doi. 10.1208/s12248-016-9996-9

By:

Maher, Sam;
Medani, Mekki;
Carballeira, Nestor;
Winter, Desmond;
Baird, Alan;
Brayden, David

Publication type:

Article

Inkjet Printing of Proteins: an Experimental Approach.

Published in:

AAPS Journal, 2017, v. 19, n. 1, p. 234, doi. 10.1208/s12248-016-9997-8

By:

Montenegro-Nicolini, Miguel;
Miranda, Víctor;
Morales, Javier

Publication type:

Article

Specific Immune Response to Phospholipase B-Like 2 Protein, a Host Cell Impurity in Lebrikizumab Clinical Material.

Published in:

AAPS Journal, 2017, v. 19, n. 1, p. 254, doi. 10.1208/s12248-016-9998-7

By:

Fischer, Saloumeh;
Cheu, Melissa;
Peng, Kun;
Lowe, John;
Araujo, James;
Murray, Elaine;
McClintock, Dana;
Matthews, John;
Siguenza, Patricia;
Song, An

Publication type:

Article

Intra-articular Injection of Urinary Bladder Matrix Reduces Osteoarthritis Development.

Published in:

AAPS Journal, 2017, v. 19, n. 1, p. 141, doi. 10.1208/s12248-016-9999-6

By:

Jacobs, Heather;
Rathod, Sona;
Wolf, Matthew;
Elisseeff, Jennifer

Publication type:

Article

Further Evaluation of Covariate Analysis using Empirical Bayes Estimates in Population Pharmacokinetics: the Perception of Shrinkage and Likelihood Ratio Test.

Published in:

AAPS Journal, 2017, v. 19, n. 1, p. 264, doi. 10.1208/s12248-016-0001-4

By:

Xu, Xu;
Yuan, Min;
Yang, Haitao;
Feng, Yan;
Xu, Jinfeng;
Pinheiro, Jose

Publication type:

Article