Works matching IS 15507416 AND DT 2016 AND VI 18 AND IP 2

Results: 25

R4 Regulator of G Protein Signaling (RGS) Proteins in Inflammation and Immunity.

Published in:

AAPS Journal, 2016, v. 18, n. 2, p. 294, doi. 10.1208/s12248-015-9847-0

By:

Xie, Zhihui;
Chan, Eunice;
Druey, Kirk

Publication type:

Article

Effects of Surface Composition on the Aerosolisation and Dissolution of Inhaled Antibiotic Combination Powders Consisting of Colistin and Rifampicin.

Published in:

AAPS Journal, 2016, v. 18, n. 2, p. 372, doi. 10.1208/s12248-015-9848-z

By:

Wang, Wenbo;
Zhou, Qi;
Sun, Si-Ping;
Denman, John;
Gengenbach, Thomas;
Barraud, Nicolas;
Rice, Scott;
Li, Jian;
Yang, Mingshi;
Chan, Hak-Kim

Publication type:

Article

Deconvolution and IVIVC: Exploring the Role of Rate-Limiting Conditions.

Published in:

AAPS Journal, 2016, v. 18, n. 2, p. 321, doi. 10.1208/s12248-015-9849-y

By:

Margolskee, Alison;
Darwich, Adam;
Galetin, Aleksandra;
Rostami-Hodjegan, Amin;
Aarons, Leon

Publication type:

Article

Neonatal Immune Tolerance Induction to Allow Long-Term Studies With an Immunogenic Therapeutic Monoclonal Antibody in Mice.

Published in:

AAPS Journal, 2016, v. 18, n. 2, p. 354, doi. 10.1208/s12248-015-9850-5

By:

Piccand, Matthieu;
Bessa, Juliana;
Schick, Eginhard;
Senn, Claudia;
Bourquin, Carole;
Richter, Wolfgang

Publication type:

Article

Utility of a Bayesian Mathematical Model to Predict the Impact of Immunogenicity on Pharmacokinetics of Therapeutic Proteins.

Published in:

AAPS Journal, 2016, v. 18, n. 2, p. 424, doi. 10.1208/s12248-015-9853-2

By:

Kathman, Steven;
Thway, Theingi;
Zhou, Lei;
Lee, Stephanie;
Yu, Steven;
Ma, Mark;
Chirmule, Naren;
Jawa, Vibha

Publication type:

Article

Intranasal Delivery of Exendin-4 Confers Neuroprotective Effect Against Cerebral Ischemia in Mice.

Published in:

AAPS Journal, 2016, v. 18, n. 2, p. 385, doi. 10.1208/s12248-015-9854-1

By:

Zhang, Huinan;
Meng, Jingru;
Zhou, Shimeng;
Liu, Yunhan;
Qu, Di;
Wang, Ling;
Li, Xubo;
Wang, Ning;
Luo, Xiaoxing;
Ma, Xue

Publication type:

Article

Ligand-Binding Assay Development: What Do You Want to Measure Versus What You Are Measuring?

Published in:

AAPS Journal, 2016, v. 18, n. 2, p. 287, doi. 10.1208/s12248-015-9855-0

By:

Mayer, Andrew;
Hottenstein, Charles

Publication type:

Article

Evaluating and Reporting the Immunogenicity Impacts for Biological Products-a Clinical Pharmacology Perspective.

Published in:

AAPS Journal, 2016, v. 18, n. 2, p. 395, doi. 10.1208/s12248-015-9857-y

By:

Wang, Yow-Ming;
Wang, Jie;
Hon, Yuen;
Zhou, Lin;
Fang, Lanyan;
Ahn, Hae

Publication type:

Article

An Integrated Strategy for Implementation of Dried Blood Spots in Clinical Development Programs.

Published in:

AAPS Journal, 2016, v. 18, n. 2, p. 519, doi. 10.1208/s12248-015-9860-3

By:

Kothare, Prajakti;
Bateman, Kevin;
Dockendorf, Marissa;
Stone, Julie;
Xu, Yang;
Woolf, Eric;
Shipley, Lisa

Publication type:

Article

Influence of Drug Properties and Formulation on In Vitro Drug Release and Biowaiver Regulation of Oral Extended Release Dosage Forms.

Published in:

AAPS Journal, 2016, v. 18, n. 2, p. 333, doi. 10.1208/s12248-015-9861-2

By:

Lin, Zhongqiang;
Zhou, Deliang;
Hoag, Stephen;
Qiu, Yihong

Publication type:

Article

Sample Management: Recommendation for Best Practices and Harmonization from the Global Bioanalysis Consortium Harmonization Team.

Published in:

AAPS Journal, 2016, v. 18, n. 2, p. 290, doi. 10.1208/s12248-016-9869-2

By:

Redrup, Michael;
Igarashi, Harue;
Schaefgen, Jay;
Lin, Jenny;
Geisler, Lisa;
Ben M'Barek, Mohamed;
Ramachandran, Subramanian;
Cardoso, Thales;
Hillewaert, Vera

Publication type:

Article

Influence of Copolymer Composition on In Vitro and In Vivo Performance of Celecoxib-PVP/VA Amorphous Solid Dispersions.

Published in:

AAPS Journal, 2016, v. 18, n. 2, p. 416, doi. 10.1208/s12248-016-9865-6

By:

Knopp, Matthias;
Nguyen, Julia;
Mu, Huiling;
Langguth, Peter;
Rades, Thomas;
Holm, René

Publication type:

Article

Preconditioning of Nonlinear Mixed Effects Models for Stabilisation of Variance-Covariance Matrix Computations.

Published in:

AAPS Journal, 2016, v. 18, n. 2, p. 505, doi. 10.1208/s12248-016-9866-5

By:

Aoki, Yasunori;
Nordgren, Rikard;
Hooker, Andrew

Publication type:

Article

In Vitro and In Vivo Human Metabolism of Synthetic Cannabinoids FDU-PB-22 and FUB-PB-22.

Published in:

AAPS Journal, 2016, v. 18, n. 2, p. 455, doi. 10.1208/s12248-016-9867-4

By:

Diao, Xingxing;
Scheidweiler, Karl;
Wohlfarth, Ariane;
Pang, Shaokun;
Kronstrand, Robert;
Huestis, Marilyn

Publication type:

Article

Prediction of Human Glomerular Filtration Rate from Preterm Neonates to Adults: Evaluation of Predictive Performance of Several Empirical Models.

Published in:

AAPS Journal, 2016, v. 18, n. 2, p. 445, doi. 10.1208/s12248-016-9868-3

By:

Mahmood, Iftekhar;
Staschen, Carl-Michael

Publication type:

Article

Improvement of Parameter Estimations in Tumor Growth Inhibition Models on Xenografted Animals: a Novel Method to Handle the Interval Censoring Caused by Measurement of Smaller Tumors.

Published in:

AAPS Journal, 2016, v. 18, n. 2, p. 404, doi. 10.1208/s12248-015-9862-1

By:

Pierrillas, Philippe;
Tod, Michel;
Amiel, Magali;
Chenel, Marylore;
Henin, Emilie

Publication type:

Article

Gender-Dependent Pharmacokinetics of Veratramine in Rats: In Vivo and In Vitro Evidence.

Published in:

AAPS Journal, 2016, v. 18, n. 2, p. 432, doi. 10.1208/s12248-016-9870-9

By:

Lyu, Chunming;
Zhang, Yufeng;
Zhou, Wenbin;
Zhang, Shen;
Kou, Fang;
Wei, Hai;
Zhang, Ning;
Zuo, Zhong

Publication type:

Article

A Human Renal Proximal Tubule Cell Line with Stable Organic Anion Transporter 1 and 3 Expression Predictive for Antiviral-Induced Toxicity.

Published in:

AAPS Journal, 2016, v. 18, n. 2, p. 465, doi. 10.1208/s12248-016-9871-8

By:

Nieskens, Tom;
Peters, Janny;
Schreurs, Marieke;
Smits, Niels;
Woestenenk, Rob;
Jansen, Katja;
Made, Thom;
Röring, Melanie;
Hilgendorf, Constanze;
Wilmer, Martijn;
Masereeuw, Rosalinde

Publication type:

Article

Evaluation of the Microcentrifuge Dissolution Method as a Tool for Spray-Dried Dispersion.

Published in:

AAPS Journal, 2016, v. 18, n. 2, p. 346, doi. 10.1208/s12248-016-9872-7

By:

Wu, Benjamin;
Li, Jinjiang;
Wang, Yahong

Publication type:

Article

An Exact Procedure for the Evaluation of Reference-Scaled Average Bioequivalence.

Published in:

AAPS Journal, 2016, v. 18, n. 2, p. 476, doi. 10.1208/s12248-016-9873-6

By:

Tothfalusi, Laszlo;
Endrenyi, Laszlo

Publication type:

Article

Advancing Product Quality: a Summary of the Second FDA/PQRI Conference.

Published in:

2016

By:

Yu, Lawrence;
Akseli, Ilgaz;
Allen, Barbara;
Amidon, Gregory;
Bizjak, Tara;
Boam, Ashley;
Caulk, Margaret;
Doleski, David;
Famulare, Joseph;
Fisher, Adam;
Furness, Scott;
Hasselbalch, Brian;
Havel, Henry;
Hoag, Stephen;
Iser, Robert;
Johnson, Bruce;
Ju, Robert;
Katz, Paula;
Lacana, Emanuela;
Lee, Sau

Publication type:

Report

Joint Model of Iron and Hepcidin During the Menstrual Cycle in Healthy Women.

Published in:

AAPS Journal, 2016, v. 18, n. 2, p. 490, doi. 10.1208/s12248-016-9875-4

By:

Angeli, Adeline;
Lainé, Fabrice;
Lavenu, Audrey;
Ropert, Martine;
Lacut, Karine;
Gissot, Valérie;
Sacher-Huvelin, Sylvie;
Jezequel, Caroline;
Moignet, Aline;
Laviolle, Bruno;
Comets, Emmanuelle

Publication type:

Article

Pre-existing Antibody: Biotherapeutic Modality-Based Review.

Published in:

AAPS Journal, 2016, v. 18, n. 2, p. 311, doi. 10.1208/s12248-016-9878-1

By:

Gorovits, Boris;
Clements-Egan, Adrienne;
Birchler, Mary;
Liang, Meina;
Myler, Heather;
Peng, Kun;
Purushothama, Shobha;
Rajadhyaksha, Manoj;
Salazar-Fontana, Laura;
Sung, Crystal;
Xue, Li

Publication type:

Article

Recent Advances on the Role of G Protein-Coupled Receptors in Hypoxia-Mediated Signaling.

Published in:

AAPS Journal, 2016, v. 18, n. 2, p. 305, doi. 10.1208/s12248-016-9881-6

By:

Lappano, Rosamaria;
Rigiracciolo, Damiano;
Marco, Paola;
Avino, Silvia;
Cappello, Anna;
Rosano, Camillo;
Maggiolini, Marcello;
Francesco, Ernestina

Publication type:

Article

Development of a Tumour Growth Inhibition Model to Elucidate the Effects of Ritonavir on Intratumoural Metabolism and Anti-tumour Effect of Docetaxel in a Mouse Model for Hereditary Breast Cancer.

Published in:

AAPS Journal, 2016, v. 18, n. 2, p. 362, doi. 10.1208/s12248-015-9838-1

By:

Yu, Huixin;
Hendrikx, Jeroen;
Rottenberg, Sven;
Schellens, Jan;
Beijnen, Jos;
Huitema, Alwin

Publication type:

Article