Works matching IS 15507416 AND DT 2015 AND VI 17 AND IP 5

Results: 25

Translating Human Effective Jejunal Intestinal Permeability to Surface-Dependent Intrinsic Permeability: a Pragmatic Method for a More Mechanistic Prediction of Regional Oral Drug Absorption.

Published in:

AAPS Journal, 2015, v. 17, n. 5, p. 1177, doi. 10.1208/s12248-015-9758-0

By:

Olivares-Morales, Andrés;
Lennernäs, Hans;
Aarons, Leon;
Rostami-Hodjegan, Amin

Publication type:

Article

Regulation of Generic Drugs in Japan: the Current Situation and Future Prospects.

Published in:

AAPS Journal, 2015, v. 17, n. 5, p. 1312, doi. 10.1208/s12248-015-9777-x

By:

Kuribayashi, Ryosuke;
Matsuhama, Maki;
Mikami, Kenichi

Publication type:

Article

Evaluation of the Biological Properties and the Enzymatic Stability of Glycosylated Luteinizing Hormone-Releasing Hormone Analogs.

Published in:

AAPS Journal, 2015, v. 17, n. 5, p. 1135, doi. 10.1208/s12248-015-9769-x

By:

Moradi, Shayli;
Varamini, Pegah;
Toth, Istvan

Publication type:

Article

Model-Based Determination of Effective Blood Concentrations of Cyclosporine for Neutrophil Response in the Treatment of Severe Aplastic Anemia in Children.

Published in:

AAPS Journal, 2015, v. 17, n. 5, p. 1157, doi. 10.1208/s12248-015-9779-8

By:

Philippe, Michaël;
Hénin, Emilie;
Bertrand, Yves;
Plantaz, Dominique;
Goutelle, Sylvain;
Bleyzac, Nathalie

Publication type:

Article

Effect of Device Design and Formulation on the In Vitro Comparability for Multi-Unit Dose Dry Powder Inhalers.

Published in:

AAPS Journal, 2015, v. 17, n. 5, p. 1105, doi. 10.1208/s12248-015-9775-z

By:

Shur, Jagdeep;
Saluja, Bhawana;
Lee, Sau;
Tibbatts, James;
Price, Robert

Publication type:

Article

Computational Advances for the Development of Allosteric Modulators and Bitopic Ligands in G Protein-Coupled Receptors.

Published in:

AAPS Journal, 2015, v. 17, n. 5, p. 1080, doi. 10.1208/s12248-015-9776-y

By:

Feng, Zhiwei;
Hu, Guanxing;
Ma, Shifan;
Xie, Xiang-Qun

Publication type:

Article

Population Pharmacokinetic Modeling of the Enterohepatic Recirculation of Fimasartan in Rats, Dogs, and Humans.

Published in:

AAPS Journal, 2015, v. 17, n. 5, p. 1210, doi. 10.1208/s12248-015-9764-2

By:

Kim, Tae;
Shin, Soyoung;
Landersdorfer, Cornelia;
Chi, Yong;
Paik, Soo;
Myung, Jayhyuk;
Yadav, Rajbharan;
Horkovics-Kovats, Stefan;
Bulitta, Jürgen;
Shin, Beom

Publication type:

Article

The Role of Megalin in the Transport of Gentamicin Across BeWo Cells, an In Vitro Model of the Human Placenta.

Published in:

AAPS Journal, 2015, v. 17, n. 5, p. 1193, doi. 10.1208/s12248-015-9778-9

By:

Akour, Amal;
Kennedy, Mary;
Gerk, Phillip

Publication type:

Article

Cellular Uptake Mechanism of Paclitaxel Nanocrystals Determined by Confocal Imaging and Kinetic Measurement.

Published in:

AAPS Journal, 2015, v. 17, n. 5, p. 1126, doi. 10.1208/s12248-015-9774-0

By:

Chen, Yan;
Li, Tonglei

Publication type:

Article

A Review of Clinical Translation of Inorganic Nanoparticles.

Published in:

AAPS Journal, 2015, v. 17, n. 5, p. 1041, doi. 10.1208/s12248-015-9780-2

By:

Anselmo, Aaron;
Mitragotri, Samir

Publication type:

Article

Application of Absorption Modeling in Rational Design of Drug Product Under Quality-by-Design Paradigm.

Published in:

AAPS Journal, 2015, v. 17, n. 5, p. 1224, doi. 10.1208/s12248-015-9781-1

By:

Kesisoglou, Filippos;
Mitra, Amitava

Publication type:

Article

Clinical Immunogenicity of rHuPH20, a Hyaluronidase Enabling Subcutaneous Drug Administration.

Published in:

AAPS Journal, 2015, v. 17, n. 5, p. 1144, doi. 10.1208/s12248-015-9782-0

By:

Rosengren, Sanna;
Dychter, Samuel;
Printz, Marie;
Huang, Lei;
Schiff, Richard;
Schwarz, Hans-Peter;
McVey, John;
Drake, Fred;
Maneval, Dan;
Kennard, Don;
Frost, Gregory;
Sugarman, Barry;
Muchmore, Douglas

Publication type:

Article

Utilizing Internal Standard Responses to Assess Risk on Reporting Bioanalytical Results from Hemolyzed Samples.

Published in:

AAPS Journal, 2015, v. 17, n. 5, p. 1168, doi. 10.1208/s12248-015-9783-z

By:

Fung, Eliza;
Aubry, Anne-Françoise;
Allentoff, Alban;
Ji, Qin

Publication type:

Article

A Method to Evaluate Fetal Erythropoiesis from Postnatal Survival of Fetal RBCs.

Published in:

AAPS Journal, 2015, v. 17, n. 5, p. 1246, doi. 10.1208/s12248-015-9784-y

By:

Kuruvilla, Denison;
Widness, John;
Nalbant, Demet;
Schmidt, Robert;
Mock, Donald;
Veng-Pedersen, Peter

Publication type:

Article

Versatility of Particulate Carriers: Development of Pharmacodynamically Optimized Drug-Loaded Microparticles for Treatment of Peritoneal Cancer.

Published in:

AAPS Journal, 2015, v. 17, n. 5, p. 1065, doi. 10.1208/s12248-015-9785-x

By:

Au, Jessie;
Lu, Ze;
Wientjes, M.

Publication type:

Article

Regulatory Considerations for Approval of Generic Inhalation Drug Products in the US, EU, Brazil, China, and India.

Published in:

2015

By:

Lee, Sau;
Saluja, Bhawana;
García-Arieta, Alfredo;
Santos, Gustavo;
Li, Ying;
Lu, Sarah;
Hou, Shuguang;
Rebello, Juliet;
Vaidya, Abhijit;
Gogtay, Jaideep;
Purandare, Shrinivas;
Lyapustina, Svetlana

Publication type:

Report

CYP3A4 Mediates Oxidative Metabolism of the Synthetic Cannabinoid AKB-48.

Published in:

AAPS Journal, 2015, v. 17, n. 5, p. 1237, doi. 10.1208/s12248-015-9788-7

By:

Holm, Niels;
Nielsen, Line;
Linnet, Kristian

Publication type:

Article

Drug Carriers: Not an Innocent Delivery Man.

Published in:

AAPS Journal, 2015, v. 17, n. 5, p. 1096, doi. 10.1208/s12248-015-9789-6

By:

Yeo, Yoon;
Kim, Bieong-Kil

Publication type:

Article

Antibody Drug Conjugates: Nonclinical Safety Considerations.

Published in:

AAPS Journal, 2015, v. 17, n. 5, p. 1055, doi. 10.1208/s12248-015-9790-0

By:

Hinrichs, Mary Jane;
Dixit, Rakesh

Publication type:

Article

Current Scientific and Regulatory Approaches for Development of Orally Inhaled and Nasal Drug Products: Overview of the IPAC-RS/University of Florida Orlando Inhalation Conference.

Published in:

2015

By:

Hochhaus, Guenther;
Davis-Cutting, Craig;
Oliver, Martin;
Lee, Sau;
Lyapustina, Svetlana

Publication type:

Report

Effect of Traumatic Brain Injury, Erythropoietin, and Anakinra on Hepatic Metabolizing Enzymes and Transporters in an Experimental Rat Model.

Published in:

AAPS Journal, 2015, v. 17, n. 5, p. 1255, doi. 10.1208/s12248-015-9792-y

By:

Anderson, Gail;
Peterson, Todd;
Vonder Haar, Cole;
Farin, Fred;
Bammler, Theo;
MacDonald, James;
Kantor, Eric;
Hoane, Michael

Publication type:

Article

Prevention of Collagen-Induced Platelet Binding and Activation by Thermosensitive Nanoparticles.

Published in:

AAPS Journal, 2015, v. 17, n. 5, p. 1117, doi. 10.1208/s12248-015-9794-9

By:

McMasters, James;
Panitch, Alyssa

Publication type:

Article

A Priori Identifiability of Target-Mediated Drug Disposition Models and Approximations.

Published in:

AAPS Journal, 2015, v. 17, n. 5, p. 1280, doi. 10.1208/s12248-015-9795-8

By:

Eudy, Rena;
Riggs, Matthew;
Gastonguay, Marc

Publication type:

Article

Are Physiologically Based Pharmacokinetic Models Reporting the Right C? Central Venous Versus Peripheral Sampling Site.

Published in:

AAPS Journal, 2015, v. 17, n. 5, p. 1268, doi. 10.1208/s12248-015-9796-7

By:

Musther, Helen;
Gill, Katherine;
Chetty, Manoranjenni;
Rostami-Hodjegan, Amin;
Rowland, Malcolm;
Jamei, Masoud

Publication type:

Article

Penetratin-Mediated Transepithelial Insulin Permeation: Importance of Cationic Residues and pH for Complexation and Permeation.

Published in:

AAPS Journal, 2015, v. 17, n. 5, p. 1200, doi. 10.1208/s12248-015-9747-3

By:

Kristensen, Mie;
Franzyk, Henrik;
Klausen, Mia;
Iversen, Anne;
Bahnsen, Jesper;
Skyggebjerg, Rikke;
Foderà, Vito;
Nielsen, Hanne

Publication type:

Article