Works matching IS 15507416 AND DT 2014 AND VI 16 AND IP 6

Results: 25

Repeat Analysis and Incurred Sample Reanalysis: Recommendation for Best Practices and Harmonization from the Global Bioanalysis Consortium Harmonization Team.
Published in:
AAPS Journal, 2014, v. 16, n. 6, p. 1167, doi. 10.1208/s12248-014-9644-1
By:
- Fluhler, Eric;
- Vazvaei, Faye;
- Singhal, Puran;
- Vinck, Petra;
- Li, Wenkui;
- Bhatt, Jignesh;
- Boer, Theo;
- Chaudhary, Ajai;
- Tangiuchi, Masahiro;
- Rezende, Vinicius;
- Zhong, Dafang
Publication type:
Article
Population Pharmacokinetic/Pharmacodynamic Modeling of Guanfacine Effects on QTc and Heart Rate in Pediatric Patients.
Published in:
AAPS Journal, 2014, v. 16, n. 6, p. 1237, doi. 10.1208/s12248-014-9645-0
By:
- Knebel, William;
- Ermer, James;
- Purkayastha, Jaideep;
- Martin, Patrick;
- Gastonguay, Marc
Publication type:
Article
A Semi-mechanistic Model for the Effects of a Novel Glucagon Receptor Antagonist on Glucagon and the Interaction Between Glucose, Glucagon, and Insulin Applied to Adaptive Phase II Design.
Published in:
AAPS Journal, 2014, v. 16, n. 6, p. 1259, doi. 10.1208/s12248-014-9648-x
By:
- Peng, Joanna;
- Denney, William;
- Musser, Bret;
- Liu, Rong;
- Tsai, Kuenhi;
- Fang, Lanyan;
- Reitman, Marc;
- Troyer, Matthew;
- Engel, Samuel;
- Xu, Lei;
- Stoch, Aubrey;
- Stone, Julie;
- Kowalski, Ken
Publication type:
Article
The Poorly Membrane Permeable Antipsychotic Drugs Amisulpride and Sulpiride Are Substrates of the Organic Cation Transporters from the SLC22 Family.
Published in:
AAPS Journal, 2014, v. 16, n. 6, p. 1247, doi. 10.1208/s12248-014-9649-9
By:
- Dos Santos Pereira, Joao;
- Tadjerpisheh, Sina;
- Abed, Manar;
- Saadatmand, Ali;
- Weksler, Babette;
- Romero, Ignacio;
- Couraud, Pierre-Olivier;
- Brockmöller, Jürgen;
- Tzvetkov, Mladen
Publication type:
Article
Method Transfer, Partial Validation, and Cross Validation: Recommendations for Best Practices and Harmonization from the Global Bioanalysis Consortium Harmonization Team.
Published in:
AAPS Journal, 2014, v. 16, n. 6, p. 1143, doi. 10.1208/s12248-014-9650-3
By:
- Briggs, R.;
- Nicholson, R.;
- Vazvaei, F.;
- Busch, J.;
- Mabuchi, M.;
- Mahesh, K.;
- Brudny-Kloeppel, M.;
- Weng, N.;
- Galvinas, P.;
- Duchene, P.;
- Hu, Pei;
- Abbott, R.
Publication type:
Article
Fmoc-Conjugated PEG-Vitamin E Micelles for Tumor-Targeted Delivery of Paclitaxel: Enhanced Drug-Carrier Interaction and Loading Capacity.
Published in:
AAPS Journal, 2014, v. 16, n. 6, p. 1282, doi. 10.1208/s12248-014-9651-2
By:
- Zhang, Yifei;
- Huang, Yixian;
- Zhao, Wenchen;
- Lu, Jianqin;
- Zhang, Peng;
- Zhang, Xiaolan;
- Li, Jiang;
- Gao, Xiang;
- Venkataramanan, Raman;
- Li, Song
Publication type:
Article
Similarities and Differences in Gastrointestinal Physiology Between Neonates and Adults: a Physiologically Based Pharmacokinetic Modeling Perspective.
Published in:
AAPS Journal, 2014, v. 16, n. 6, p. 1162, doi. 10.1208/s12248-014-9652-1
By:
- Yu, Guo;
- Zheng, Qing-Shan;
- Li, Guo-Fu
Publication type:
Article
Retrospective Data Analysis and Proposal of a Practical Acceptance Criterion for Inter-laboratory Cross-validation of Bioanalytical Methods Using Liquid Chromatography/Tandem Mass Spectrometry.
Published in:
AAPS Journal, 2014, v. 16, n. 6, p. 1226, doi. 10.1208/s12248-014-9653-0
By:
- Yoneyama, Tomoki;
- Kudo, Takashi;
- Jinno, Fumihiro;
- Schmidt, Eric;
- Kondo, Takahiro
Publication type:
Article
Structure, Size, and Solubility of Antigen Arrays Determines Efficacy in Experimental Autoimmune Encephalomyelitis.
Published in:
AAPS Journal, 2014, v. 16, n. 6, p. 1185, doi. 10.1208/s12248-014-9654-z
By:
- Sestak, Joshua;
- Fakhari, Amir;
- Badawi, Ahmed;
- Siahaan, Teruna;
- Berkland, Cory
Publication type:
Article
Modeling of Bounded Outcome Scores with Data on the Boundaries: Application to Disability Assessment for Dementia Scores in Alzheimer's Disease.
Published in:
AAPS Journal, 2014, v. 16, n. 6, p. 1271, doi. 10.1208/s12248-014-9655-y
By:
- Xu, Xu;
- Samtani, Mahesh;
- Yuan, Min;
- Nandy, Partha
Publication type:
Article
Predicting Pediatric Age-Matched Weight and Body Mass Index.
Published in:
AAPS Journal, 2014, v. 16, n. 6, p. 1372, doi. 10.1208/s12248-014-9657-9
By:
- Sy, Sherwin;
- Asin-Prieto, Eduardo;
- Derendorf, Hartmut;
- Samara, Emil
Publication type:
Article
Evaluation of Acoustic Membrane Microparticle (AMMP) Technology for a Sensitive Ligand Binding Assay to Support Pharmacokinetic Determinations of a Biotherapeutic.
Published in:
AAPS Journal, 2014, v. 16, n. 6, p. 1366, doi. 10.1208/s12248-014-9659-7
By:
- Chilewski, Shannon;
- Dickerson, W.;
- Mora, Johanna;
- Saab, Ashley;
- Alderman, Edward
Publication type:
Article
Next Generation Ligand Binding Assays-Review of Emerging Technologies' Capabilities to Enhance Throughput and Multiplexing.
Published in:
AAPS Journal, 2014, v. 16, n. 6, p. 1175, doi. 10.1208/s12248-014-9660-1
By:
- Mora, Johanna;
- Chunyk, Allison;
- Dysinger, Mark;
- Purushothama, Shobha;
- Ricks, Claude;
- Österlund, Karolina;
- Theobald, Valerie
Publication type:
Article
Reference Datasets for 2-Treatment, 2-Sequence, 2-Period Bioequivalence Studies.
Published in:
AAPS Journal, 2014, v. 16, n. 6, p. 1292, doi. 10.1208/s12248-014-9661-0
By:
- Schütz, Helmut;
- Labes, Detlew;
- Fuglsang, Anders
Publication type:
Article
A Therapeutic Microparticle-Based Tumor Lysate Vaccine Reduces Spontaneous Metastases in Murine Breast Cancer.
Published in:
AAPS Journal, 2014, v. 16, n. 6, p. 1194, doi. 10.1208/s12248-014-9662-z
By:
- Gross, Brett;
- Wongrakpanich, Amaraporn;
- Francis, Meghan;
- Salem, Aliasger;
- Norian, Lyse
Publication type:
Article
Reliability and Extension of Quantitative Prediction of CYP3A4-Mediated Drug Interactions Based on Clinical Data.
Published in:
AAPS Journal, 2014, v. 16, n. 6, p. 1309, doi. 10.1208/s12248-014-9663-y
By:
- Loue, Constance;
- Tod, Michel
Publication type:
Article
Elucidation of Arctigenin Pharmacokinetics After Intravenous and Oral Administrations in Rats: Integration of In Vitro and In Vivo Findings via Semi-mechanistic Pharmacokinetic Modeling.
Published in:
AAPS Journal, 2014, v. 16, n. 6, p. 1321, doi. 10.1208/s12248-014-9664-x
By:
- Gao, Qiong;
- Zhang, Yufeng;
- Wo, Siukwan;
- Zuo, Zhong
Publication type:
Article
Design and Evaluation of Thioalkylated Mannose-Modified Dendrimer (G3)/α-Cyclodextrin Conjugates as Antigen-Presenting Cell-Selective siRNA Carriers.
Published in:
AAPS Journal, 2014, v. 16, n. 6, p. 1298, doi. 10.1208/s12248-014-9665-9
By:
- Motoyama, Keiichi;
- Mitsuyasu, Ryosuke;
- Akao, Chiho;
- Tanaka, Takahiro;
- Ohyama, Ayumu;
- Sato, Nana;
- Higashi, Taishi;
- Arima, Hidetoshi
Publication type:
Article
Blocking of JB6 Cell Transformation by Tanshinone IIA: Epigenetic Reactivation of Nrf2 Antioxidative Stress Pathway.
Published in:
AAPS Journal, 2014, v. 16, n. 6, p. 1214, doi. 10.1208/s12248-014-9666-8
By:
- Wang, Ling;
- Zhang, Chengyue;
- Guo, Yue;
- Su, Zheng-Yuan;
- Yang, Yuqing;
- Shu, Limin;
- Kong, Ah-Ng
Publication type:
Article
Prediction of Drug Clearance in Children: an Evaluation of the Predictive Performance of Several Models.
Published in:
AAPS Journal, 2014, v. 16, n. 6, p. 1334, doi. 10.1208/s12248-014-9667-7
By:
- Mahmood, Iftekhar;
- Staschen, Carl-Michael;
- Goteti, Kosalaram
Publication type:
Article
Systematic Verification of Bioanalytical Similarity Between a Biosimilar and a Reference Biotherapeutic: Committee Recommendations for the Development and Validation of a Single Ligand-Binding Assay to Support Pharmacokinetic Assessments.
Published in:
AAPS Journal, 2014, v. 16, n. 6, p. 1149, doi. 10.1208/s12248-014-9669-5
By:
- Marini, Joseph;
- Anderson, Michael;
- Cai, Xiao-Yan;
- Chappell, John;
- Coffey, Todd;
- Gouty, Dominique;
- Kasinath, Aparna;
- Koppenburg, Vera;
- Oldfield, Philip;
- Rebarchak, Shannon;
- Bowsher, Ronald
Publication type:
Article
Co-Delivery of Autoantigen and B7 Pathway Modulators Suppresses Experimental Autoimmune Encephalomyelitis.
Published in:
AAPS Journal, 2014, v. 16, n. 6, p. 1204, doi. 10.1208/s12248-014-9671-y
By:
- Northrup, Laura;
- Sestak, Joshua;
- Sullivan, Bradley;
- Thati, Sharadvi;
- Hartwell, Brittany;
- Siahaan, Teruna;
- Vines, Charlotte;
- Berkland, Cory
Publication type:
Article
Toward the Establishment of Standardized In Vitro Tests for Lipid-Based Formulations, Part 6: Effects of Varying Pancreatin and Calcium Levels.
Published in:
AAPS Journal, 2014, v. 16, n. 6, p. 1344, doi. 10.1208/s12248-014-9672-x
By:
- Sassene, Philip;
- Kleberg, Karen;
- Williams, Hywel;
- Bakala-N'Goma, Jean-Claude;
- Carrière, Frédéric;
- Calderone, Marilyn;
- Jannin, Vincent;
- Igonin, Annabel;
- Partheil, Anette;
- Marchaud, Delphine;
- Jule, Eduardo;
- Vertommen, Jan;
- Maio, Mario;
- Blundell, Ross;
- Benameur, Hassan;
- Porter, Christopher;
- Pouton, Colin;
- Müllertz, Anette
Publication type:
Article
The Use of Betaine HCl to Enhance Dasatinib Absorption in Healthy Volunteers with Rabeprazole-Induced Hypochlorhydria.
Published in:
AAPS Journal, 2014, v. 16, n. 6, p. 1358, doi. 10.1208/s12248-014-9673-9
By:
- Yago, Marc;
- Frymoyer, Adam;
- Benet, Leslie;
- Smelick, Gillian;
- Frassetto, Lynda;
- Ding, Xiao;
- Dean, Brian;
- Salphati, Laurent;
- Budha, Nageshwar;
- Jin, Jin;
- Dresser, Mark;
- Ware, Joseph
Publication type:
Article
Introduction to the Proposals from the Global Bioanalysis Consortium Harmonization Team.
Published in:
2014
By:
- Timmerman, Philip;
- Arnold, Mark;
- DeSilva, Binodh;
- Garofolo, Fabio;
- Golob, Michaela;
- Amsterdam, Peter;
- Kudoh, Shinobu;
- Singhal, Puran;
- Tang, Daniel;
- Riccio, Maria;
- Barrientos, Rafael;
- Savale, Shrinivas;
- Kurokawa, Tatsuo
Publication type:
Editorial