Works matching IS 15507416 AND DT 2014 AND VI 16 AND IP 6

Results: 25

Method Transfer, Partial Validation, and Cross Validation: Recommendations for Best Practices and Harmonization from the Global Bioanalysis Consortium Harmonization Team.

Published in:

AAPS Journal, 2014, v. 16, n. 6, p. 1143, doi. 10.1208/s12248-014-9650-3

By:

Briggs, R.;
Nicholson, R.;
Vazvaei, F.;
Busch, J.;
Mabuchi, M.;
Mahesh, K.;
Brudny-Kloeppel, M.;
Weng, N.;
Galvinas, P.;
Duchene, P.;
Hu, Pei;
Abbott, R.

Publication type:

Article

Fmoc-Conjugated PEG-Vitamin E Micelles for Tumor-Targeted Delivery of Paclitaxel: Enhanced Drug-Carrier Interaction and Loading Capacity.

Published in:

AAPS Journal, 2014, v. 16, n. 6, p. 1282, doi. 10.1208/s12248-014-9651-2

By:

Zhang, Yifei;
Huang, Yixian;
Zhao, Wenchen;
Lu, Jianqin;
Zhang, Peng;
Zhang, Xiaolan;
Li, Jiang;
Gao, Xiang;
Venkataramanan, Raman;
Li, Song

Publication type:

Article

Predicting Pediatric Age-Matched Weight and Body Mass Index.

Published in:

AAPS Journal, 2014, v. 16, n. 6, p. 1372, doi. 10.1208/s12248-014-9657-9

By:

Sy, Sherwin;
Asin-Prieto, Eduardo;
Derendorf, Hartmut;
Samara, Emil

Publication type:

Article

Repeat Analysis and Incurred Sample Reanalysis: Recommendation for Best Practices and Harmonization from the Global Bioanalysis Consortium Harmonization Team.

Published in:

AAPS Journal, 2014, v. 16, n. 6, p. 1167, doi. 10.1208/s12248-014-9644-1

By:

Fluhler, Eric;
Vazvaei, Faye;
Singhal, Puran;
Vinck, Petra;
Li, Wenkui;
Bhatt, Jignesh;
Boer, Theo;
Chaudhary, Ajai;
Tangiuchi, Masahiro;
Rezende, Vinicius;
Zhong, Dafang

Publication type:

Article

Population Pharmacokinetic/Pharmacodynamic Modeling of Guanfacine Effects on QTc and Heart Rate in Pediatric Patients.

Published in:

AAPS Journal, 2014, v. 16, n. 6, p. 1237, doi. 10.1208/s12248-014-9645-0

By:

Knebel, William;
Ermer, James;
Purkayastha, Jaideep;
Martin, Patrick;
Gastonguay, Marc

Publication type:

Article

A Semi-mechanistic Model for the Effects of a Novel Glucagon Receptor Antagonist on Glucagon and the Interaction Between Glucose, Glucagon, and Insulin Applied to Adaptive Phase II Design.

Published in:

AAPS Journal, 2014, v. 16, n. 6, p. 1259, doi. 10.1208/s12248-014-9648-x

By:

Peng, Joanna;
Denney, William;
Musser, Bret;
Liu, Rong;
Tsai, Kuenhi;
Fang, Lanyan;
Reitman, Marc;
Troyer, Matthew;
Engel, Samuel;
Xu, Lei;
Stoch, Aubrey;
Stone, Julie;
Kowalski, Ken

Publication type:

Article

The Poorly Membrane Permeable Antipsychotic Drugs Amisulpride and Sulpiride Are Substrates of the Organic Cation Transporters from the SLC22 Family.

Published in:

AAPS Journal, 2014, v. 16, n. 6, p. 1247, doi. 10.1208/s12248-014-9649-9

By:

Dos Santos Pereira, Joao;
Tadjerpisheh, Sina;
Abed, Manar;
Saadatmand, Ali;
Weksler, Babette;
Romero, Ignacio;
Couraud, Pierre-Olivier;
Brockmöller, Jürgen;
Tzvetkov, Mladen

Publication type:

Article

The Use of Betaine HCl to Enhance Dasatinib Absorption in Healthy Volunteers with Rabeprazole-Induced Hypochlorhydria.

Published in:

AAPS Journal, 2014, v. 16, n. 6, p. 1358, doi. 10.1208/s12248-014-9673-9

By:

Yago, Marc;
Frymoyer, Adam;
Benet, Leslie;
Smelick, Gillian;
Frassetto, Lynda;
Ding, Xiao;
Dean, Brian;
Salphati, Laurent;
Budha, Nageshwar;
Jin, Jin;
Dresser, Mark;
Ware, Joseph

Publication type:

Article

Similarities and Differences in Gastrointestinal Physiology Between Neonates and Adults: a Physiologically Based Pharmacokinetic Modeling Perspective.

Published in:

AAPS Journal, 2014, v. 16, n. 6, p. 1162, doi. 10.1208/s12248-014-9652-1

By:

Yu, Guo;
Zheng, Qing-Shan;
Li, Guo-Fu

Publication type:

Article

Retrospective Data Analysis and Proposal of a Practical Acceptance Criterion for Inter-laboratory Cross-validation of Bioanalytical Methods Using Liquid Chromatography/Tandem Mass Spectrometry.

Published in:

AAPS Journal, 2014, v. 16, n. 6, p. 1226, doi. 10.1208/s12248-014-9653-0

By:

Yoneyama, Tomoki;
Kudo, Takashi;
Jinno, Fumihiro;
Schmidt, Eric;
Kondo, Takahiro

Publication type:

Article

Structure, Size, and Solubility of Antigen Arrays Determines Efficacy in Experimental Autoimmune Encephalomyelitis.

Published in:

AAPS Journal, 2014, v. 16, n. 6, p. 1185, doi. 10.1208/s12248-014-9654-z

By:

Sestak, Joshua;
Fakhari, Amir;
Badawi, Ahmed;
Siahaan, Teruna;
Berkland, Cory

Publication type:

Article

Modeling of Bounded Outcome Scores with Data on the Boundaries: Application to Disability Assessment for Dementia Scores in Alzheimer's Disease.

Published in:

AAPS Journal, 2014, v. 16, n. 6, p. 1271, doi. 10.1208/s12248-014-9655-y

By:

Xu, Xu;
Samtani, Mahesh;
Yuan, Min;
Nandy, Partha

Publication type:

Article

Evaluation of Acoustic Membrane Microparticle (AMMP) Technology for a Sensitive Ligand Binding Assay to Support Pharmacokinetic Determinations of a Biotherapeutic.

Published in:

AAPS Journal, 2014, v. 16, n. 6, p. 1366, doi. 10.1208/s12248-014-9659-7

By:

Chilewski, Shannon;
Dickerson, W.;
Mora, Johanna;
Saab, Ashley;
Alderman, Edward

Publication type:

Article

Next Generation Ligand Binding Assays-Review of Emerging Technologies' Capabilities to Enhance Throughput and Multiplexing.

Published in:

AAPS Journal, 2014, v. 16, n. 6, p. 1175, doi. 10.1208/s12248-014-9660-1

By:

Mora, Johanna;
Chunyk, Allison;
Dysinger, Mark;
Purushothama, Shobha;
Ricks, Claude;
Österlund, Karolina;
Theobald, Valerie

Publication type:

Article

Reference Datasets for 2-Treatment, 2-Sequence, 2-Period Bioequivalence Studies.

Published in:

AAPS Journal, 2014, v. 16, n. 6, p. 1292, doi. 10.1208/s12248-014-9661-0

By:

Schütz, Helmut;
Labes, Detlew;
Fuglsang, Anders

Publication type:

Article

A Therapeutic Microparticle-Based Tumor Lysate Vaccine Reduces Spontaneous Metastases in Murine Breast Cancer.

Published in:

AAPS Journal, 2014, v. 16, n. 6, p. 1194, doi. 10.1208/s12248-014-9662-z

By:

Gross, Brett;
Wongrakpanich, Amaraporn;
Francis, Meghan;
Salem, Aliasger;
Norian, Lyse

Publication type:

Article

Reliability and Extension of Quantitative Prediction of CYP3A4-Mediated Drug Interactions Based on Clinical Data.

Published in:

AAPS Journal, 2014, v. 16, n. 6, p. 1309, doi. 10.1208/s12248-014-9663-y

By:

Loue, Constance;
Tod, Michel

Publication type:

Article

Elucidation of Arctigenin Pharmacokinetics After Intravenous and Oral Administrations in Rats: Integration of In Vitro and In Vivo Findings via Semi-mechanistic Pharmacokinetic Modeling.

Published in:

AAPS Journal, 2014, v. 16, n. 6, p. 1321, doi. 10.1208/s12248-014-9664-x

By:

Gao, Qiong;
Zhang, Yufeng;
Wo, Siukwan;
Zuo, Zhong

Publication type:

Article

Design and Evaluation of Thioalkylated Mannose-Modified Dendrimer (G3)/α-Cyclodextrin Conjugates as Antigen-Presenting Cell-Selective siRNA Carriers.

Published in:

AAPS Journal, 2014, v. 16, n. 6, p. 1298, doi. 10.1208/s12248-014-9665-9

By:

Motoyama, Keiichi;
Mitsuyasu, Ryosuke;
Akao, Chiho;
Tanaka, Takahiro;
Ohyama, Ayumu;
Sato, Nana;
Higashi, Taishi;
Arima, Hidetoshi

Publication type:

Article

Blocking of JB6 Cell Transformation by Tanshinone IIA: Epigenetic Reactivation of Nrf2 Antioxidative Stress Pathway.

Published in:

AAPS Journal, 2014, v. 16, n. 6, p. 1214, doi. 10.1208/s12248-014-9666-8

By:

Wang, Ling;
Zhang, Chengyue;
Guo, Yue;
Su, Zheng-Yuan;
Yang, Yuqing;
Shu, Limin;
Kong, Ah-Ng

Publication type:

Article

Prediction of Drug Clearance in Children: an Evaluation of the Predictive Performance of Several Models.

Published in:

AAPS Journal, 2014, v. 16, n. 6, p. 1334, doi. 10.1208/s12248-014-9667-7

By:

Mahmood, Iftekhar;
Staschen, Carl-Michael;
Goteti, Kosalaram

Publication type:

Article

Systematic Verification of Bioanalytical Similarity Between a Biosimilar and a Reference Biotherapeutic: Committee Recommendations for the Development and Validation of a Single Ligand-Binding Assay to Support Pharmacokinetic Assessments.

Published in:

AAPS Journal, 2014, v. 16, n. 6, p. 1149, doi. 10.1208/s12248-014-9669-5

By:

Marini, Joseph;
Anderson, Michael;
Cai, Xiao-Yan;
Chappell, John;
Coffey, Todd;
Gouty, Dominique;
Kasinath, Aparna;
Koppenburg, Vera;
Oldfield, Philip;
Rebarchak, Shannon;
Bowsher, Ronald

Publication type:

Article

Co-Delivery of Autoantigen and B7 Pathway Modulators Suppresses Experimental Autoimmune Encephalomyelitis.

Published in:

AAPS Journal, 2014, v. 16, n. 6, p. 1204, doi. 10.1208/s12248-014-9671-y

By:

Northrup, Laura;
Sestak, Joshua;
Sullivan, Bradley;
Thati, Sharadvi;
Hartwell, Brittany;
Siahaan, Teruna;
Vines, Charlotte;
Berkland, Cory

Publication type:

Article

Toward the Establishment of Standardized In Vitro Tests for Lipid-Based Formulations, Part 6: Effects of Varying Pancreatin and Calcium Levels.

Published in:

AAPS Journal, 2014, v. 16, n. 6, p. 1344, doi. 10.1208/s12248-014-9672-x

By:

Sassene, Philip;
Kleberg, Karen;
Williams, Hywel;
Bakala-N'Goma, Jean-Claude;
Carrière, Frédéric;
Calderone, Marilyn;
Jannin, Vincent;
Igonin, Annabel;
Partheil, Anette;
Marchaud, Delphine;
Jule, Eduardo;
Vertommen, Jan;
Maio, Mario;
Blundell, Ross;
Benameur, Hassan;
Porter, Christopher;
Pouton, Colin;
Müllertz, Anette

Publication type:

Article

Introduction to the Proposals from the Global Bioanalysis Consortium Harmonization Team.

Published in:

2014

By:

Timmerman, Philip;
Arnold, Mark;
DeSilva, Binodh;
Garofolo, Fabio;
Golob, Michaela;
Amsterdam, Peter;
Kudoh, Shinobu;
Singhal, Puran;
Tang, Daniel;
Riccio, Maria;
Barrientos, Rafael;
Savale, Shrinivas;
Kurokawa, Tatsuo

Publication type:

Editorial