Works matching IS 15507416 AND DT 2014 AND VI 16 AND IP 4

Results: 25

Quantitative Targeted Proteomics for Membrane Transporter Proteins: Method and Application.

Published in:

AAPS Journal, 2014, v. 16, n. 4, p. 714, doi. 10.1208/s12248-014-9607-6

By:

Qiu, Xi;
Zhang, Hui;
Lai, Yurong

Publication type:

Article

In Vitro Characterization of a Novel Polymeric System for Preparation of Amorphous Solid Drug Dispersions.

Published in:

AAPS Journal, 2014, v. 16, n. 4, p. 685, doi. 10.1208/s12248-014-9590-y

By:

Mahmoudi, Zahra;
Upadhye, Sampada;
Ferrizzi, David;
Rajabi-Siahboomi, Ali

Publication type:

Article

Pharmacokinetics and Pharmacodynamics of Phenethyl Isothiocyanate: Implications in Breast Cancer Prevention.

Published in:

AAPS Journal, 2014, v. 16, n. 4, p. 705, doi. 10.1208/s12248-014-9610-y

By:

Morris, Marilyn;
Dave, Rutwij

Publication type:

Article

Release Behaviour of Single Pellets and Internal Fine 3D Structural Features Co-define the In Vitro Drug Release Profile.

Published in:

AAPS Journal, 2014, v. 16, n. 4, p. 860, doi. 10.1208/s12248-014-9611-x

By:

Yang, Shuo;
Yin, Xianzhen;
Wang, Caifen;
Li, Haiyan;
He, You;
Xiao, Tiqiao;
Sun, Lixin;
Li, Jiasheng;
York, Peter;
He, Jun;
Zhang, Jiwen

Publication type:

Article

Understanding Pharmaceutical Quality by Design.

Published in:

AAPS Journal, 2014, v. 16, n. 4, p. 771, doi. 10.1208/s12248-014-9598-3

By:

Yu, Lawrence;
Amidon, Gregory;
Khan, Mansoor;
Hoag, Stephen;
Polli, James;
Raju, G.;
Woodcock, Janet

Publication type:

Article

Measurement of Subvisible Particulates in Lyophilised Erwinia chrysanthemi l-asparaginase and Relationship with Clinical Experience.

Published in:

AAPS Journal, 2014, v. 16, n. 4, p. 784, doi. 10.1208/s12248-014-9612-9

By:

Gervais, David;
Corn, Tim;
Downer, Andrew;
Smith, Stuart;
Jennings, Alan

Publication type:

Article

Statistical Comparison of Dissolution Profiles to Predict the Bioequivalence of Extended Release Formulations.

Published in:

AAPS Journal, 2014, v. 16, n. 4, p. 791, doi. 10.1208/s12248-014-9615-6

By:

Gomez-Mantilla, J.;
Schaefer, U.;
Casabo, V.;
Lehr, T.;
Lehr, C.

Publication type:

Article

Mechanistic Modeling of Monocarboxylate Transporter-Mediated Toxicokinetic/Toxicodynamic Interactions Between γ-Hydroxybutyrate and l-Lactate.

Published in:

AAPS Journal, 2014, v. 16, n. 4, p. 756, doi. 10.1208/s12248-014-9593-8

By:

Morse, Bridget;
Vijay, Nisha;
Morris, Marilyn

Publication type:

Article

When Assay Format Matters: a Case Study on the Evaluation of Three Assay Formats to Support a Clinical Pharmacokinetic Study.

Published in:

AAPS Journal, 2014, v. 16, n. 4, p. 625, doi. 10.1208/s12248-014-9594-7

By:

Peng, Kun;
Baker, Dana;
Brignoli, Suzanne;
Cabuhat, Janis;
Fischer, Saloumeh

Publication type:

Article

Practical Considerations for Dose Selection in Pediatric Patients to Ensure Target Exposure Requirements.

Published in:

AAPS Journal, 2014, v. 16, n. 4, p. 749, doi. 10.1208/s12248-014-9603-x

By:

Barbour, April;
Fossler, Michael;
Barrett, Jeffrey

Publication type:

Article

A Sequential Bioequivalence Design with a Potential Ethical Advantage.

Published in:

AAPS Journal, 2014, v. 16, n. 4, p. 843, doi. 10.1208/s12248-014-9622-7

By:

Fuglsang, Anders

Publication type:

Article

Impact-Insertion Applicator Improves Reliability of Skin Penetration by Solid Microneedle Arrays.

Published in:

AAPS Journal, 2014, v. 16, n. 4, p. 681, doi. 10.1208/s12248-014-9606-7

By:

Maaden, Koen;
Sekerdag, Emine;
Jiskoot, Wim;
Bouwstra, Joke

Publication type:

Article

Simplification of Complex Physiologically Based Pharmacokinetic Models of Monoclonal Antibodies.

Published in:

AAPS Journal, 2014, v. 16, n. 4, p. 810, doi. 10.1208/s12248-014-9591-x

By:

Elmeliegy, Mohamed;
Lowe, Philip;
Krzyzanski, Wojciech

Publication type:

Article

Progressively Reducing Regulatory Burden.

Published in:

AAPS Journal, 2014, v. 16, n. 4, p. 621, doi. 10.1208/s12248-014-9601-z

By:

Shah, Vinod;
Cecil, Todd;
Srinivasan, Srini;
Williams, Roger

Publication type:

Article

Permeability Comparison between Hepatocyte and Low Efflux MDCKII Cell Monolayer.

Published in:

AAPS Journal, 2014, v. 16, n. 4, p. 802, doi. 10.1208/s12248-014-9616-5

By:

Li, Rui;
Bi, Yi-An;
Lai, Yurong;
Sugano, Kiyohiko;
Steyn, Stefanus;
Trapa, Patrick;
Di, Li

Publication type:

Article

Anti-HIV Drug Development Through Computational Methods.

Published in:

AAPS Journal, 2014, v. 16, n. 4, p. 674, doi. 10.1208/s12248-014-9604-9

By:

Gu, Wan-Gang;
Zhang, Xuan;
Yuan, Jun-Fa

Publication type:

Article

Solid Lipid Particles for Oral Delivery of Peptide and Protein Drugs III - the Effect of Fed State Conditions on the In Vitro Release and Degradation of Desmopressin.

Published in:

AAPS Journal, 2014, v. 16, n. 4, p. 875, doi. 10.1208/s12248-014-9619-2

By:

Christophersen, Philip;
Vaghela, Dimple;
Müllertz, Anette;
Yang, Mingshi;
Nielsen, Hanne;
Mu, Huiling

Publication type:

Article

Nanomedicine Drug Development: A Scientific Symposium Entitled 'Charting a Roadmap to Commercialization'.

Published in:

2014

By:

Finch, Gregory;
Havel, Henry;
Analoui, Mostafa;
Barton, Randall;
Diwan, Anil;
Hennessy, Meliessa;
Reddy, Vijayapal;
Sadrieh, Nakissa;
Tamarkin, Lawrence;
Wolfgang, Marc;
Yerxa, Benjamin;
Zolnik, Banu;
Liu, Man

Publication type:

Report

Optimized Approaches for Quantification of Drug Transporters in Tissues and Cells by MRM Proteomics.

Published in:

AAPS Journal, 2014, v. 16, n. 4, p. 634, doi. 10.1208/s12248-014-9602-y

By:

Prasad, Bhagwat;
Unadkat, Jashvant

Publication type:

Article

Many Approved Drugs Have Bioactive Analogs With Different Target Annotations.

Published in:

AAPS Journal, 2014, v. 16, n. 4, p. 847, doi. 10.1208/s12248-014-9621-8

By:

Hu, Ye;
Lounkine, Eugen;
Bajorath, Jürgen

Publication type:

Article

The Gender of Cell Lines Matters When Screening for Novel Anti-Cancer Drugs.

Published in:

AAPS Journal, 2014, v. 16, n. 4, p. 872, doi. 10.1208/s12248-014-9617-4

By:

Nunes, Larissa;
Robles-Escajeda, Elisa;
Santiago-Vazquez, Yahaira;
Ortega, Nora;
Lema, Carolina;
Muro, Almendra;
Almodovar, Gladys;
Das, Umashankar;
Das, Swagatika;
Dimmock, Johnatan;
Aguilera, Renato;
Varela-Ramirez, Armando

Publication type:

Article

Mechanism-Based Pharmacokinetic Modeling to Evaluate Transporter-Enzyme Interplay in Drug Interactions and Pharmacogenetics of Glyburide.

Published in:

AAPS Journal, 2014, v. 16, n. 4, p. 736, doi. 10.1208/s12248-014-9614-7

By:

Varma, Manthena;
Scialis, Renato;
Lin, Jian;
Bi, Yi-An;
Rotter, Charles;
Goosen, Theunis;
Yang, Xin

Publication type:

Article

Assessment and Reporting of the Clinical Immunogenicity of Therapeutic Proteins and Peptides-Harmonized Terminology and Tactical Recommendations.

Published in:

AAPS Journal, 2014, v. 16, n. 4, p. 658, doi. 10.1208/s12248-014-9599-2

By:

Shankar, G.;
Arkin, S.;
Cocea, L.;
Devanarayan, V.;
Kirshner, S.;
Kromminga, A.;
Quarmby, V.;
Richards, S.;
Schneider, C.;
Subramanyam, M.;
Swanson, S.;
Verthelyi, D.;
Yim, S.

Publication type:

Article

Apigenin Reactivates Nrf2 Anti-oxidative Stress Signaling in Mouse Skin Epidermal JB6 P + Cells Through Epigenetics Modifications.

Published in:

AAPS Journal, 2014, v. 16, n. 4, p. 727, doi. 10.1208/s12248-014-9613-8

By:

Paredes-Gonzalez, Ximena;
Fuentes, Francisco;
Su, Zheng-Yuan;
Kong, Ah-Ng

Publication type:

Article

Curcumin Inhibits the AKT/NF-κB Signaling via CpG Demethylation of the Promoter and Restoration of NEP in the N2a Cell Line.

Published in:

AAPS Journal, 2014, v. 16, n. 4, p. 649, doi. 10.1208/s12248-014-9605-8

By:

Deng, Yushuang;
Lu, Xi;
Wang, Li;
Li, Tao;
Ding, Yubin;
Cao, Huimin;
Zhang, Yuping;
Guo, Xiuming;
Yu, Gang

Publication type:

Article