Works matching IS 15507416 AND DT 2014 AND VI 16 AND IP 3

Results: 25

Changes in Individual Drug-Independent System Parameters during Virtual Paediatric Pharmacokinetic Trials: Introducing Time-Varying Physiology into a Paediatric PBPK Model.

Published in:

AAPS Journal, 2014, v. 16, n. 3, p. 568, doi. 10.1208/s12248-014-9592-9

By:

Abduljalil, Khaled;
Jamei, Masoud;
Rostami-Hodjegan, Amin;
Johnson, Trevor N.

Publication type:

Article

A Population Pharmacodynamic Model for Lactate Dehydrogenase and Neuron Specific Enolase to Predict Tumor Progression in Small Cell Lung Cancer Patients.

Published in:

AAPS Journal, 2014, v. 16, n. 3, p. 609, doi. 10.1208/s12248-014-9600-0

By:

Buil-Bruna, Núria;
López-Picazo, José-María;
Moreno-Jiménez, Marta;
Martín-Algarra, Salvador;
Ribba, Benjamin;
Trocóniz, Iñaki F.

Publication type:

Article

Bioanalytical Method Validation: Concepts, Expectations and Challenges in Small Molecule and Macromolecule—A Report of PITTCON 2013 Symposium.

Published in:

AAPS Journal, 2014, v. 16, n. 3, p. 586, doi. 10.1208/s12248-014-9597-4

By:

Bashaw, Edward D.;
DeSilva, Binodh;
Rose, Mark J.;
Wang, Yow-Ming C.;
Shukla, Chinmay

Publication type:

Article

Rapid Delivery of Diazepam from Supersaturated Solutions Prepared Using Prodrug/Enzyme Mixtures: Toward Intranasal Treatment of Seizure Emergencies.

Published in:

AAPS Journal, 2014, v. 16, n. 3, p. 577, doi. 10.1208/s12248-014-9596-5

By:

Kapoor, Mamta;
Winter, Tate;
Lis, Lev;
Georg, Gunda I.;
Siegel, Ronald A.

Publication type:

Article

Screening of Bioactive Peptides Using an Embryonic Stem Cell-Based Neurodifferentiation Assay.

Published in:

AAPS Journal, 2014, v. 16, n. 3, p. 400, doi. 10.1208/s12248-014-9578-7

By:

Xu, Ruodan;
Feyeux, Maxime;
Julien, Stéphanie;
Nemes, Csilla;
Albrechtsen, Morten;
Dinnyés, Andras;
Krause, Karl-Heinz

Publication type:

Article

New FDA Draft Guidance on Immunogenicity.

Published in:

AAPS Journal, 2014, v. 16, n. 3, p. 499, doi. 10.1208/s12248-014-9587-6

By:

Parenky, Ashwin;
Myler, Heather;
Amaravadi, Lakshmi;
Bechtold-Peters, Karoline;
Rosenberg, Amy;
Kirshner, Susan;
Quarmby, Valerie

Publication type:

Article

Sequential Bioequivalence Approaches for Parallel Designs.

Published in:

AAPS Journal, 2014, v. 16, n. 3, p. 373, doi. 10.1208/s12248-014-9571-1

By:

Fuglsang, Anders

Publication type:

Article

Mapping the Target Localization and Biodistribution of Non-Radiolabeled VMAT2 Ligands in rat Brain.

Published in:

AAPS Journal, 2014, v. 16, n. 3, p. 592, doi. 10.1208/s12248-014-9584-9

By:

Deng, Aifang;
Wu, Xianying;
Zhou, Xue;
Zhang, Yan;
Yin, Wei;
Qiao, Jinping;
Zhu, Lin

Publication type:

Article

Development of a Method That Eliminates False-Positive Results due to Nerve Growth Factor Interference in the Assessment of Fulranumab Immunogenicity.

Published in:

AAPS Journal, 2014, v. 16, n. 3, p. 464, doi. 10.1208/s12248-014-9581-z

By:

Dai, Sheng;
Schantz, Allen;
Clements-Egan, Adrienne;
Cannon, Michael;
Shankar, Gopi

Publication type:

Article

In Vitro Lipolysis Data Does Not Adequately Predict the In Vivo Performance of Lipid-Based Drug Delivery Systems Containing Fenofibrate.

Published in:

AAPS Journal, 2014, v. 16, n. 3, p. 539, doi. 10.1208/s12248-014-9589-4

By:

Thomas, Nicky;
Richter, Katharina;
Pedersen, Thomas B.;
Holm, René;
Müllertz, Anette;
Rades, Thomas

Publication type:

Article

Determination of the Most Influential Sources of Variability in Tacrolimus Trough Blood Concentrations in Adult Liver Transplant Recipients: A Bottom-Up Approach.

Published in:

AAPS Journal, 2014, v. 16, n. 3, p. 379, doi. 10.1208/s12248-014-9577-8

By:

Gérard, Cécile;
Stocco, Jeanick;
Hulin, Anne;
Blanchet, Benoit;
Verstuyft, Céline;
Durand, François;
Conti, Filomena;
Duvoux, Christophe;
Tod, Michel

Publication type:

Article

Role of Public Standards in the Safety and Efficacy of Biologic Medicines.

Published in:

AAPS Journal, 2014, v. 16, n. 3, p. 516, doi. 10.1208/s12248-014-9586-7

By:

Williams, Roger L.;
Bristow, Adrian F.;
Hauck, Walter W.;
Srinivasan, V. Srini;
Morris, Tina;
Atouf, Fouad;
Ambrose, Michael;
Surendranath, Koduru V.;
Chakrabarty, Ranjan;
Menon, Krishna

Publication type:

Article

Novel Lansoprazole-Loaded Nanoparticles for the Treatment of Gastric Acid Secretion-Related Ulcers: In Vitro and In Vivo Pharmacokinetic Pharmacodynamic Evaluation.

Published in:

AAPS Journal, 2014, v. 16, n. 3, p. 361, doi. 10.1208/s12248-014-9564-0

By:

Alai, Milind;
Lin, Wen Jen

Publication type:

Article

Commentary: Current Perspectives on the Aggregation of Protein Drugs.

Published in:

AAPS Journal, 2014, v. 16, n. 3, p. 413, doi. 10.1208/s12248-014-9580-0

By:

Topp, Elizabeth M.

Publication type:

Article

Polymeric nanocarriers for transport modulation across the pulmonary epithelium: dendrimers, polymeric nanoparticles, and their nanoblends.

Published in:

AAPS Journal, 2014, v. 16, n. 3, p. 522, doi. 10.1208/s12248-014-9588-5

By:

Bharatwaj, Balaji;
Dimovski, Radovan;
Conti, Denise S.;
da Rocha, Sandro R. P.

Publication type:

Article

Multiscale Tumor Spatiokinetic Model for Intraperitoneal Therapy.

Published in:

AAPS Journal, 2014, v. 16, n. 3, p. 424, doi. 10.1208/s12248-014-9574-y

By:

Au, Jessie L.-S.;
Peng Guo;
Yue Gao;
Ze Lu;
Wientjes, Michael G.;
sai, Max T.;
Wientjes, M. Guillaume

Publication type:

Article

Influence of Surface Chemistry on Cytotoxicity and Cellular Uptake of Nanocapsules in Breast Cancer and Phagocytic Cells.

Published in:

AAPS Journal, 2014, v. 16, n. 3, p. 550, doi. 10.1208/s12248-014-9572-0

By:

Youm, Ibrahima;
Bazzil, Joseph D.;
Otto, Joseph W.;
Caruso, Anthony N.;
Murowchick, James B.;
Youan, Bi-Botti C.

Publication type:

Article

Evaluation of Estimation Methods and Power of Tests of Discrete Covariates in Repeated Time-to-Event Parametric Models: Application to Gaucher Patients Treated by Imiglucerase.

Published in:

AAPS Journal, 2014, v. 16, n. 3, p. 415, doi. 10.1208/s12248-014-9575-x

By:

Vigan, Marie;
Stirnemann, Jérôme;
Mentré, France

Publication type:

Article

Targeted Delivery of Curcumin to Tumors via PEG-Derivatized FTS-Based Micellar System.

Published in:

AAPS Journal, 2014, v. 16, n. 3, p. 600, doi. 10.1208/s12248-014-9595-6

By:

Yichao Chen;
Xiaolan Zhang;
Jianqin Lu;
Yixian Huang;
Jiang Li;
Song Li

Publication type:

Article

Analyzing Subvisible Particles in Protein Drug Products: a Comparison of Dynamic Light Scattering (DLS) and Resonant Mass Measurement (RMM).

Published in:

AAPS Journal, 2014, v. 16, n. 3, p. 440, doi. 10.1208/s12248-014-9579-6

By:

Panchal, Jainik;
Kotarek, Joseph;
Marszal, Ewa;
Topp, Elizabeth M.

Publication type:

Article

A Network Modeling Approach for the Spatial Distribution and Structure of Bone Mineral Content.

Published in:

AAPS Journal, 2014, v. 16, n. 3, p. 478, doi. 10.1208/s12248-014-9585-8

By:

Hui Li;
Aidong Zhang;
Bone, Lawrence;
Buyea, Cathy;
Ramanathan, Murali

Publication type:

Article

Ligand Binding Assay Critical Reagents and Their Stability: Recommendations and Best Practices from the Global Bioanalysis Consortium Harmonization Team.

Published in:

AAPS Journal, 2014, v. 16, n. 3, p. 504, doi. 10.1208/s12248-014-9583-x

By:

King, Lindsay;
Farley, Esme;
Imazato, Mami;
Keefe, Jeannine;
Khan, Masood;
Ma, Mark;
Pihl, K.;
Sriraman, Priya

Publication type:

Article

A Priori Prediction of Tumor Payload Concentrations: Preclinical Case Study with an Auristatin-Based Anti-5T4 Antibody-Drug Conjugate.

Published in:

AAPS Journal, 2014, v. 16, n. 3, p. 452, doi. 10.1208/s12248-014-9576-9

By:

Shah, Dhaval K.;
King, Lindsay E.;
Xiaogang Han;
Wentland, Jo-Ann;
Yanhua Zhang;
Lucas, Judy;
Haddish-Berhane, Nahor;
Betts, Alison;
Leal, Mauricio

Publication type:

Article

A White Paper-Consensus and Recommendations of a Global Harmonization Team on Assessing the Impact of Immunogenicity on Pharmacokinetic Measurements.

Published in:

AAPS Journal, 2014, v. 16, n. 3, p. 488, doi. 10.1208/s12248-014-9582-y

By:

Sailstad, J.;
Amaravadi, L.;
Clements-Egan, A.;
Gorovits, B.;
Myler, H.;
Pillutla, R.;
Pursuhothama, S.;
Putman, M.;
Rose, M.;
Sonehara, K.;
Tang, L.;
Wustner, J.

Publication type:

Article

Stability: Recommendation for Best Practices and Harmonization from the Global Bioanalysis Consortium Harmonization Team.

Published in:

AAPS Journal, 2014, v. 16, n. 3, p. 392, doi. 10.1208/s12248-014-9573-z

By:

van de Merbel, Nico;
Savoie, Natasha;
Yadav, Manish;
Ohtsu, Yoshiaki;
White, Joleen;
Riccio, Maria;
Dong, Kelly;
de Vries, Ronald;
Diancin, Julie

Publication type:

Article