Works matching IS 15507416 AND DT 2013 AND VI 15 AND IP 3

Results: 27

Theoretical Considerations and Practical Approaches to Address the Effect of Anti-drug Antibody (ADA) on Quantification of Biotherapeutics in Circulation.

Published in:

AAPS Journal, 2013, v. 15, n. 3, p. 646, doi. 10.1208/s12248-013-9468-4

By:

Kelley, Marian;
Ahene, Ago;
Gorovits, Boris;
Kamerud, John;
King, Lindsay;
McIntosh, Thomas;
Yang, Jihong

Publication type:

Article

Engineered Mannitol Ternary Additives Improve Dispersion of Lactose-Salbutamol Sulphate Dry Powder Inhalations.

Published in:

AAPS Journal, 2013, v. 15, n. 3, p. 728, doi. 10.1208/s12248-013-9476-4

By:

Kaialy, Waseem;
Nokhodchi, Ali

Publication type:

Article

Generic Development of Topical Dermatologic Products, Part II: Quality by Design for Topical Semisolid Products.

Published in:

AAPS Journal, 2013, v. 15, n. 3, p. 674, doi. 10.1208/s12248-013-9472-8

By:

Chang, Rong-Kun;
Raw, Andre;
Lionberger, Robert;
Yu, Lawrence

Publication type:

Article

Resveratrol Suppresses T0901317-Induced Hepatic Fat Accumulation in Mice.

Published in:

AAPS Journal, 2013, v. 15, n. 3, p. 744, doi. 10.1208/s12248-013-9473-7

By:

Gao, Mingming;
Liu, Dexi

Publication type:

Article

Comparative In Silico- In Vivo Evaluation of ASGP-R Ligands for Hepatic Targeting of Curcumin Gantrez Nanoparticles.

Published in:

AAPS Journal, 2013, v. 15, n. 3, p. 696, doi. 10.1208/s12248-013-9474-6

By:

D'Souza, Anisha;
Jain, Puneet;
Galdhar, C.;
Samad, Abdul;
Degani, Mariam;
Devarajan, Padma

Publication type:

Article

Sequential Bioequivalence Trial Designs with Increased Power and Controlled Type I Error Rates.

Published in:

AAPS Journal, 2013, v. 15, n. 3, p. 659, doi. 10.1208/s12248-013-9475-5

By:

Fuglsang, Anders

Publication type:

Article

Drug-Drug Interaction Studies: Regulatory Guidance and An Industry Perspective.

Published in:

AAPS Journal, 2013, v. 15, n. 3, p. 629, doi. 10.1208/s12248-013-9470-x

By:

Prueksaritanont, Thomayant;
Chu, Xiaoyan;
Gibson, Christopher;
Cui, Donghui;
Yee, Ka;
Ballard, Jeanine;
Cabalu, Tamara;
Hochman, Jerome

Publication type:

Article

Factors Influencing Magnitude and Duration of Target Inhibition Following Antibody Therapy: Implications in Drug Discovery and Development.

Published in:

AAPS Journal, 2013, v. 15, n. 3, p. 717, doi. 10.1208/s12248-013-9477-3

By:

Chimalakonda, Anjaneya;
Yadav, Rajbharan;
Marathe, Punit

Publication type:

Article

Predictive Models of Diffusive Nanoparticle Transport in 3-Dimensional Tumor Cell Spheroids.

Published in:

AAPS Journal, 2013, v. 15, n. 3, p. 816, doi. 10.1208/s12248-013-9478-2

By:

Gao, Yue;
Li, Mingguang;
Chen, Bin;
Shen, Zancong;
Guo, Peng;
Wientjes, M.;
Au, Jessie

Publication type:

Article

Clinical Pharmacokinetics of Buffered Propranolol Sublingual Tablet (Promptol™)-Application of a New 'Physiologically Based' Model to Assess Absorption and Disposition.

Published in:

AAPS Journal, 2013, v. 15, n. 3, p. 787, doi. 10.1208/s12248-013-9479-1

By:

Wang, Yanfeng;
Wang, Zhijun;
Zuo, Zhong;
Tomlinson, Brian;
Lee, Benjamin;
Bolger, Michael;
Chow, Moses

Publication type:

Article

Development of a Preclinical PK/PD Model to Assess Antitumor Response of a Sequential Aflibercept and Doxorubicin-Dosing Strategy in Acute Myeloid Leukemia.

Published in:

AAPS Journal, 2013, v. 15, n. 3, p. 662, doi. 10.1208/s12248-013-9480-8

By:

Fetterly, Gerald;
Aras, Urvi;
Lal, Deepika;
Murphy, Michael;
Meholick, Patricia;
Wang, Eunice

Publication type:

Article

Nonlinear Absorption Kinetics of Self-Emulsifying Drug Delivery Systems (SEDDS) Containing Tocotrienols as Lipophilic Molecules: In Vivo and In Vitro Studies.

Published in:

AAPS Journal, 2013, v. 15, n. 3, p. 684, doi. 10.1208/s12248-013-9481-7

By:

Alqahtani, Saeed;
Alayoubi, Alaadin;
Nazzal, Sami;
Sylvester, Paul;
Kaddoumi, Amal

Publication type:

Article

Assessment of Juvenile Pigs to Serve as Human Pediatric Surrogates for Preclinical Formulation Pharmacokinetic Testing.

Published in:

AAPS Journal, 2013, v. 15, n. 3, p. 763, doi. 10.1208/s12248-013-9482-6

By:

Roth, Wyatt;
Kissinger, Candice;
McCain, Robyn;
Cooper, Bruce;
Marchant-Forde, Jeremy;
Vreeman, Rachel;
Hannou, Sophia;
Knipp, Gregory

Publication type:

Article

Mathematical Model Approach to Describe Tumour Response in Mice After Vaccine Administration and its Applicability to Immune-Stimulatory Cytokine-Based Strategies.

Published in:

AAPS Journal, 2013, v. 15, n. 3, p. 797, doi. 10.1208/s12248-013-9483-5

By:

Parra-Guillen, Zinnia;
Berraondo, Pedro;
Grenier, Emmanuel;
Ribba, Benjamin;
Troconiz, Iñaki

Publication type:

Article

Impact of Anti-Drug Antibodies in Preclinical Pharmacokinetic Assessment.

Published in:

AAPS Journal, 2013, v. 15, n. 3, p. 856, doi. 10.1208/s12248-013-9484-4

By:

Thway, Theingi;
Magana, Ivan;
Bautista, Ami;
Jawa, Vibha;
Gu, Wen;
Ma, Mark

Publication type:

Article

Non-Arrhenius Protein Aggregation.

Published in:

AAPS Journal, 2013, v. 15, n. 3, p. 840, doi. 10.1208/s12248-013-9485-3

By:

Wang, Wei;
Roberts, Christopher

Publication type:

Article

Molecular Mechanisms of Silibinin-Mediated Cancer Chemoprevention with Major Emphasis on Prostate Cancer.

Published in:

AAPS Journal, 2013, v. 15, n. 3, p. 707, doi. 10.1208/s12248-013-9486-2

By:

Ting, Harold;
Deep, Gagan;
Agarwal, Rajesh

Publication type:

Article

Effect of Censoring Due to Progressive Disease on Tumor Size Kinetic Parameter Estimates.

Published in:

2013

By:

Bonate, Peter;
Suttle, Ben

Publication type:

Report

Epigenetic Modifications of Nrf2 by 3,3′-diindolylmethane In Vitro in TRAMP C1 Cell Line and In Vivo TRAMP Prostate Tumors.

Published in:

AAPS Journal, 2013, v. 15, n. 3, p. 864, doi. 10.1208/s12248-013-9493-3

By:

Wu, Tien-Yuan;
Khor, Tin;
Su, Zheng-Yuan;
Saw, Constance;
Shu, Limin;
Cheung, Ka-Lung;
Huang, Ying;
Yu, Siwang;
Kong, Ah-Ng

Publication type:

Article

Bioequivalence for Locally Acting Nasal Spray and Nasal Aerosol Products: Standard Development and Generic Approval.

Published in:

AAPS Journal, 2013, v. 15, n. 3, p. 875, doi. 10.1208/s12248-013-9494-2

By:

Li, Bing;
Jin, Feiyan;
Lee, Sau;
Bai, Tao;
Chowdhury, Badrul;
Caramenico, Hoainhon;
Conner, Dale

Publication type:

Article

CDER Risk Assessment Exercise to Evaluate Potential Risks from the Use of Nanomaterials in Drug Products.

Published in:

AAPS Journal, 2013, v. 15, n. 3, p. 623, doi. 10.1208/s12248-013-9466-6

By:

Cruz, Celia;
Tyner, Katherine;
Velazquez, Lydia;
Hyams, Kenneth;
Jacobs, Abigail;
Shaw, Arthur;
Jiang, Wenlei;
Lionberger, Robert;
Hinderling, Peter;
Kong, Yoon;
Brown, Paul;
Ghosh, Tapash;
Strasinger, Caroline;
Suarez-Sharp, Sandra;
Henry, Don;
Uitert, Maat;
Sadrieh, Nakissa;
Morefield, Elaine

Publication type:

Article

Protective Effects of Kaempferol on Isoniazid- and Rifampicin-Induced Hepatotoxicity.

Published in:

AAPS Journal, 2013, v. 15, n. 3, p. 753, doi. 10.1208/s12248-013-9490-6

By:

Shih, Tung-Yuan;
Young, Ton-Ho;
Lee, Herng-Sheng;
Hsieh, Chung-Bao;
Hu, Oliver

Publication type:

Article

Pre-Existing Biotherapeutic-Reactive Antibodies: Survey Results Within the American Association of Pharmaceutical Scientists.

Published in:

AAPS Journal, 2013, v. 15, n. 3, p. 852, doi. 10.1208/s12248-013-9492-4

By:

Xue, Li;
Fiscella, Michele;
Rajadhyaksha, Manoj;
Goyal, Jaya;
Holland, Claire;
Gorovits, Boris;
Morimoto, Alyssa

Publication type:

Article

What is the Likelihood of an Active Compound to Be Promiscuous? Systematic Assessment of Compound Promiscuity on the Basis of PubChem Confirmatory Bioassay Data.

Published in:

AAPS Journal, 2013, v. 15, n. 3, p. 808, doi. 10.1208/s12248-013-9488-0

By:

Hu, Ye;
Bajorath, Jürgen

Publication type:

Article

Risk Assessment of Drug Interaction Potential and Concomitant Dosing Pattern on Targeted Toxicities in Pediatric Cancer Patients.

Published in:

AAPS Journal, 2013, v. 15, n. 3, p. 775, doi. 10.1208/s12248-013-9489-z

By:

Barrett, Jeffrey;
Patel, Dimple;
Dombrowsky, Erin;
Bajaj, Gaurav;
Skolnik, Jeffrey

Publication type:

Article

Evaluation of Pre-existing Antibody Presence as a Risk Factor for Posttreatment Anti-drug Antibody Induction: Analysis of Human Clinical Study Data for Multiple Biotherapeutics.

Published in:

AAPS Journal, 2013, v. 15, n. 3, p. 893, doi. 10.1208/s12248-013-9497-z

By:

Xue, Li;
Rup, Bonita

Publication type:

Article

Utilization of Gene Expression Signature for Quality Control of Traditional Chinese Medicine Formula Si-Wu-Tang.

Published in:

AAPS Journal, 2013, v. 15, n. 3, p. 884, doi. 10.1208/s12248-013-9491-5

By:

Xie, Chen;
Wang, Zhijun;
Wang, Charles;
Xu, Jun;
Wen, Zhining;
Wang, Haitian;
Shi, Leming;
Chow, Moses;
Huang, Ying;
Zuo, Zhong

Publication type:

Article