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The Solubility-Permeability Interplay and Its Implications in Formulation Design and Development for Poorly Soluble Drugs.
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- AAPS Journal, 2012, v. 14, n. 2, p. 244, doi. 10.1208/s12248-012-9337-6
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- Article
A mechanism-Based Approach for Absorption Modeling: The Gastro-Intestinal Transit Time (GITT) Model.
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- AAPS Journal, 2012, v. 14, n. 2, p. 155, doi. 10.1208/s12248-012-9324-y
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- Article
Population Analyses of Efficacy and Safety of ABT-594 in Subjects with Diabetic Peripheral Neuropathic Pain.
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- AAPS Journal, 2012, v. 14, n. 2, p. 168, doi. 10.1208/s12248-012-9328-7
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- Article
Benet L Z and Galeazzi R L: Noncompartmental Determination of the Steady-State Volume of Distribution, J Pharm Sci 68, 1071-1074, 1979-the Backstory.
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- AAPS Journal, 2012, v. 14, n. 2, p. 164, doi. 10.1208/s12248-012-9326-9
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- Article
Rapid Sample Size Calculations for a Defined Likelihood Ratio Test-Based Power in Mixed-Effects Models.
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- AAPS Journal, 2012, v. 14, n. 2, p. 176, doi. 10.1208/s12248-012-9327-8
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- Article
Cutaneous Microdialysis: Cytokine Evidence for Altered Innate Reactivity in the Skin of Psoriasis Patients?
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- AAPS Journal, 2012, v. 14, n. 2, p. 187, doi. 10.1208/s12248-012-9331-z
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- Article
An Investigation into the Utility of a Multi-compartmental, Dynamic, System of the Upper Gastrointestinal Tract to Support Formulation Development and Establish Bioequivalence of Poorly Soluble Drugs.
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- AAPS Journal, 2012, v. 14, n. 2, p. 196, doi. 10.1208/s12248-012-9333-x
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- Article
Issues and Challenges of Subvisible and Submicron Particulate Analysis in Protein Solutions.
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- AAPS Journal, 2012, v. 14, n. 2, p. 236, doi. 10.1208/s12248-012-9335-8
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- Article
Conformational Analysis of Therapeutic Proteins by Hydroxyl Radical Protein Footprinting.
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- AAPS Journal, 2012, v. 14, n. 2, p. 206, doi. 10.1208/s12248-012-9336-7
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- Article
Design and Characterization of Novel Peptide-Coated Lipid Nanoparticles for Targeting Anti-HIV Drug to CD4 Expressing Cells.
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- AAPS Journal, 2012, v. 14, n. 2, p. 225, doi. 10.1208/s12248-012-9329-6
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- Article
Pharmacokinetics, Lymph Node Uptake, and Mechanistic PK Model of Near-Infrared Dye-Labeled Bevacizumab After IV and SC Administration in Mice.
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- AAPS Journal, 2012, v. 14, n. 2, p. 252, doi. 10.1208/s12248-012-9342-9
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- Article
Pharmacokinetic Evaluation of Intranasally Administered Vinyl Polymer-Coated Lorazepam Microparticles in Rabbits.
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- AAPS Journal, 2012, v. 14, n. 2, p. 218, doi. 10.1208/s12248-012-9325-x
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- Article
Applications of Human Pharmacokinetic Prediction in First-in-Human Dose Estimation.
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- AAPS Journal, 2012, v. 14, n. 2, p. 262, doi. 10.1208/s12248-012-9332-y
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- Article
Challenges in Development of Nanoparticle-Based Therapeutics.
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- AAPS Journal, 2012, v. 14, n. 2, p. 282, doi. 10.1208/s12248-012-9339-4
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- Article
Ligand Binding Assays in the 21st Century Laboratory: Recommendations for Characterization and Supply of Critical Reagents.
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- AAPS Journal, 2012, v. 14, n. 2, p. 316, doi. 10.1208/s12248-012-9334-9
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- Article
Immunogenicity to Therapeutic Proteins: Impact on PK/PD and Efficacy.
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- AAPS Journal, 2012, v. 14, n. 2, p. 296, doi. 10.1208/s12248-012-9340-y
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- Article
Challenges in Development of Targeted Liposomal Therapeutics.
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- AAPS Journal, 2012, v. 14, n. 2, p. 303, doi. 10.1208/s12248-012-9330-0
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- Article
Role of Metabolism in the Effects of Genistein and Its Phase II Conjugates on the Growth of Human Breast Cell Lines.
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- AAPS Journal, 2012, v. 14, n. 2, p. 329, doi. 10.1208/s12248-012-9338-5
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- Article
Acarbose Bioequivalence: Exploration of New Pharmacodynamic Parameters.
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- AAPS Journal, 2012, v. 14, n. 2, p. 345, doi. 10.1208/s12248-012-9341-x
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- Article
A Physiologically Based Pharmacokinetic Model of Mitoxantrone in Mice and Scale-up to Humans: a Semi-Mechanistic Model Incorporating DNA and Protein Binding.
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- AAPS Journal, 2012, v. 14, n. 2, p. 352, doi. 10.1208/s12248-012-9344-7
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- Article
Mechanism-Based Pharmacokinetic/Pharmacodynamic Modeling of Rat Prefrontal Cortical Dopamine Response to Dual Acting Norepinephrine Reuptake Inhibitor and 5-HT Partial Agonist.
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- AAPS Journal, 2012, v. 14, n. 2, p. 365, doi. 10.1208/s12248-012-9343-8
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- Article