Works matching IS 15507416 AND DT 2012 AND VI 14 AND IP 2

Results: 21

Benet L Z and Galeazzi R L: Noncompartmental Determination of the Steady-State Volume of Distribution, J Pharm Sci 68, 1071-1074, 1979-the Backstory.

Published in:

AAPS Journal, 2012, v. 14, n. 2, p. 164, doi. 10.1208/s12248-012-9326-9

By:

Benet, Leslie

Publication type:

Article

Population Analyses of Efficacy and Safety of ABT-594 in Subjects with Diabetic Peripheral Neuropathic Pain.

Published in:

AAPS Journal, 2012, v. 14, n. 2, p. 168, doi. 10.1208/s12248-012-9328-7

By:

Dutta, Sandeep;
Hosmane, Balakrishna;
Awni, Walid

Publication type:

Article

The Solubility-Permeability Interplay and Its Implications in Formulation Design and Development for Poorly Soluble Drugs.

Published in:

AAPS Journal, 2012, v. 14, n. 2, p. 244, doi. 10.1208/s12248-012-9337-6

By:

Dahan, Arik;
Miller, Jonathan

Publication type:

Article

A mechanism-Based Approach for Absorption Modeling: The Gastro-Intestinal Transit Time (GITT) Model.

Published in:

AAPS Journal, 2012, v. 14, n. 2, p. 155, doi. 10.1208/s12248-012-9324-y

By:

Hénin, Emilie;
Bergstrand, Martin;
Standing, Joseph;
Karlsson, Mats

Publication type:

Article

Rapid Sample Size Calculations for a Defined Likelihood Ratio Test-Based Power in Mixed-Effects Models.

Published in:

AAPS Journal, 2012, v. 14, n. 2, p. 176, doi. 10.1208/s12248-012-9327-8

By:

Vong, Camille;
Bergstrand, Martin;
Nyberg, Joakim;
Karlsson, Mats

Publication type:

Article

Cutaneous Microdialysis: Cytokine Evidence for Altered Innate Reactivity in the Skin of Psoriasis Patients?

Published in:

AAPS Journal, 2012, v. 14, n. 2, p. 187, doi. 10.1208/s12248-012-9331-z

By:

Sjögren, Florence;
Davidsson, Karin;
Sjöström, Michael;
Anderson, Chris

Publication type:

Article

An Investigation into the Utility of a Multi-compartmental, Dynamic, System of the Upper Gastrointestinal Tract to Support Formulation Development and Establish Bioequivalence of Poorly Soluble Drugs.

Published in:

AAPS Journal, 2012, v. 14, n. 2, p. 196, doi. 10.1208/s12248-012-9333-x

By:

Dickinson, Paul;
Abu Rmaileh, Ragheb;
Ashworth, Lee;
Barker, Richard;
Burke, Wendy;
Patterson, Claire;
Stainforth, Nick;
Yasin, Mohammed

Publication type:

Article

Conformational Analysis of Therapeutic Proteins by Hydroxyl Radical Protein Footprinting.

Published in:

AAPS Journal, 2012, v. 14, n. 2, p. 206, doi. 10.1208/s12248-012-9336-7

By:

Watson, Caroline;
Sharp, Joshua

Publication type:

Article

Issues and Challenges of Subvisible and Submicron Particulate Analysis in Protein Solutions.

Published in:

AAPS Journal, 2012, v. 14, n. 2, p. 236, doi. 10.1208/s12248-012-9335-8

By:

Scherer, Thomas;
Leung, Stephenie;
Owyang, Laura;
Shire, Steven

Publication type:

Article

Design and Characterization of Novel Peptide-Coated Lipid Nanoparticles for Targeting Anti-HIV Drug to CD4 Expressing Cells.

Published in:

AAPS Journal, 2012, v. 14, n. 2, p. 225, doi. 10.1208/s12248-012-9329-6

By:

Endsley, Aaron;
Ho, Rodney

Publication type:

Article

Pharmacokinetics, Lymph Node Uptake, and Mechanistic PK Model of Near-Infrared Dye-Labeled Bevacizumab After IV and SC Administration in Mice.

Published in:

AAPS Journal, 2012, v. 14, n. 2, p. 252, doi. 10.1208/s12248-012-9342-9

By:

Wu, Fang;
Tamhane, Mitalee;
Morris, Marilyn

Publication type:

Article

Pharmacokinetic Evaluation of Intranasally Administered Vinyl Polymer-Coated Lorazepam Microparticles in Rabbits.

Published in:

AAPS Journal, 2012, v. 14, n. 2, p. 218, doi. 10.1208/s12248-012-9325-x

By:

Zhao, Yanjun;
Brown, Marc;
Khengar, Rajeshree;
Traynor, Matthew;
Barata, Pedro;
Jones, Stuart

Publication type:

Article

Applications of Human Pharmacokinetic Prediction in First-in-Human Dose Estimation.

Published in:

AAPS Journal, 2012, v. 14, n. 2, p. 262, doi. 10.1208/s12248-012-9332-y

By:

Zou, Peng;
Yu, Yanke;
Zheng, Nan;
Yang, Yongsheng;
Paholak, Hayley;
Yu, Lawrence;
Sun, Duxin

Publication type:

Article

Challenges in Development of Nanoparticle-Based Therapeutics.

Published in:

AAPS Journal, 2012, v. 14, n. 2, p. 282, doi. 10.1208/s12248-012-9339-4

By:

Desai, Neil

Publication type:

Article

Immunogenicity to Therapeutic Proteins: Impact on PK/PD and Efficacy.

Published in:

AAPS Journal, 2012, v. 14, n. 2, p. 296, doi. 10.1208/s12248-012-9340-y

By:

Chirmule, Narendra;
Jawa, Vibha;
Meibohm, Bernd

Publication type:

Article

Challenges in Development of Targeted Liposomal Therapeutics.

Published in:

AAPS Journal, 2012, v. 14, n. 2, p. 303, doi. 10.1208/s12248-012-9330-0

By:

Sawant, Rupa;
Torchilin, Vladimir

Publication type:

Article

Role of Metabolism in the Effects of Genistein and Its Phase II Conjugates on the Growth of Human Breast Cell Lines.

Published in:

AAPS Journal, 2012, v. 14, n. 2, p. 329, doi. 10.1208/s12248-012-9338-5

By:

Yuan, Bo;
Wang, Linglan;
Jin, Yi;
Zhen, Huijuan;
Xu, Pingwei;
Xu, Youjun;
Li, Chibing;
Xu, Haiyan

Publication type:

Article

Acarbose Bioequivalence: Exploration of New Pharmacodynamic Parameters.

Published in:

AAPS Journal, 2012, v. 14, n. 2, p. 345, doi. 10.1208/s12248-012-9341-x

By:

Zhang, Min;
Yang, Jin;
Tao, Lei;
Li, Lingjun;
Ma, Pengcheng;
Fawcett, John

Publication type:

Article

A Physiologically Based Pharmacokinetic Model of Mitoxantrone in Mice and Scale-up to Humans: a Semi-Mechanistic Model Incorporating DNA and Protein Binding.

Published in:

AAPS Journal, 2012, v. 14, n. 2, p. 352, doi. 10.1208/s12248-012-9344-7

By:

An, Guohua;
Morris, Marilyn

Publication type:

Article

Mechanism-Based Pharmacokinetic/Pharmacodynamic Modeling of Rat Prefrontal Cortical Dopamine Response to Dual Acting Norepinephrine Reuptake Inhibitor and 5-HT Partial Agonist.

Published in:

AAPS Journal, 2012, v. 14, n. 2, p. 365, doi. 10.1208/s12248-012-9343-8

By:

Li, Cheryl;
Zhang, Liming;
Haske, Taraneh;
Dounay, Amy;
Gray, David;
Barta, Nancy;
Brodfuehrer, Joanne;
Lepsy, Christopher;
Campbell, Brian

Publication type:

Article

Ligand Binding Assays in the 21st Century Laboratory: Recommendations for Characterization and Supply of Critical Reagents.

Published in:

AAPS Journal, 2012, v. 14, n. 2, p. 316, doi. 10.1208/s12248-012-9334-9

By:

O'Hara, Denise;
Theobald, Valerie;
Egan, Adrienne;
Usansky, Joel;
Krishna, Murli;
TerWee, Julie;
Maia, Mauricio;
Spriggs, Frank;
Kenney, John;
Safavi, Afshin;
Keefe, Jeannine

Publication type:

Article