Works matching IS 15507416 AND DT 2009 AND VI 11 AND IP 2

Results: 21

“Fit-for-Purpose” Method Validation and Application of a Biomarker (C-terminal Telopeptides of Type 1 Collagen) in Denosumab Clinical Studies.

Published in:

AAPS Journal, 2009, v. 11, n. 2, p. 385, doi. 10.1208/s12248-009-9115-2

By:

Wang, Jin;
Lee, Jean;
Burns, Daniel;
Doherty, David;
Brunner, Laura;
Peterson, Mark;
DeSilva, Binodh

Publication type:

Article

An Investigation into the Importance of “Very Rapid Dissolution” Criteria for Drug Bioequivalence Demonstration using Gastrointestinal Simulation Technology.

Published in:

AAPS Journal, 2009, v. 11, n. 2, p. 381, doi. 10.1208/s12248-009-9114-3

By:

Kovačevi, Ivan;
Parojči, Jelena;
Tubi-Grozdanis, Marija;
Langguth, Peter

Publication type:

Article

The H<sub>2</sub> Receptor Antagonist Nizatidine is a P-Glycoprotein Substrate: Characterization of its Intestinal Epithelial Cell Efflux Transport.

Published in:

AAPS Journal, 2009, v. 11, n. 2, p. 205, doi. 10.1208/s12248-009-9092-5

By:

Dahan, Arik;
Sabit, Hairat;
Amidon, Gordon

Publication type:

Article

AAPS–FIP Summary Workshop Report: Pharmacogenetics in Individualized Medicine: Methods, Regulatory, and Clinical Applications.

Published in:

2009

By:

Moridani, Majid;
Maitland-van der Zee, Anke-Hilse;
Sasaki, Hitoshi;
McKinnon, Ross;
Fleckenstein, Lawrence;
Shah, Vinod

Publication type:

Report

Handling Data Below the Limit of Quantification in Mixed Effect Models.

Published in:

AAPS Journal, 2009, v. 11, n. 2, p. 371, doi. 10.1208/s12248-009-9112-5

By:

Bergstrand, Martin;
Karlsson, Mats

Publication type:

Article

Structure-Based Prediction of the Nonspecific Binding of Drugs to Hepatic Microsomes.

Published in:

AAPS Journal, 2009, v. 11, n. 2, p. 364, doi. 10.1208/s12248-009-9113-4

By:

Li, Haiyan;
Sun, Jin;
Sui, Xiaofan;
Yan, Zhongtian;
Sun, Yinghua;
Liu, Xiaohong;
Wang, Yongjun;
He, Zhonggui

Publication type:

Article

Simulations of the Nonlinear Dose Dependence for Substrates of Influx and Efflux Transporters in the Human Intestine.

Published in:

AAPS Journal, 2009, v. 11, n. 2, p. 353, doi. 10.1208/s12248-009-9111-6

By:

Bolger, Michael;
Lukacova, Viera;
Woltosz, Walter

Publication type:

Article

Prediction of Modified Release Pharmacokinetics and Pharmacodynamics from In Vitro, Immediate Release, and Intravenous Data.

Published in:

AAPS Journal, 2009, v. 11, n. 2, p. 323, doi. 10.1208/s12248-009-9107-2

By:

Lukacova, Viera;
Woltosz, Walter;
Bolger, Michael

Publication type:

Article

Peptide Kappa Opioid Receptor Ligands: Potential for Drug Development.

Published in:

AAPS Journal, 2009, v. 11, n. 2, p. 312, doi. 10.1208/s12248-009-9105-4

By:

Aldrich, Jane;
McLaughlin, Jay

Publication type:

Article

Inhibitors of Endocannabinoid-Metabolizing Enzymes Reduce Precipitated Withdrawal Responses in THC-Dependent Mice.

Published in:

AAPS Journal, 2009, v. 11, n. 2, p. 342, doi. 10.1208/s12248-009-9110-7

By:

Schlosburg, Joel;
Carlson, Brittany;
Ramesh, Divya;
Abdullah, Rehab;
Long, Jonathan;
Cravatt, Benjamin;
Lichtman, Aron

Publication type:

Article

Measuring Endocannabinoid Hydrolysis: Refining our Tools and Understanding.

Published in:

AAPS Journal, 2009, v. 11, n. 2, p. 307, doi. 10.1208/s12248-009-9109-0

By:

Marrs, William;
Stella, Nephi

Publication type:

Article

Predicting Drug–Drug Interactions: An FDA Perspective.

Published in:

AAPS Journal, 2009, v. 11, n. 2, p. 300, doi. 10.1208/s12248-009-9106-3

By:

Zhang, Lei;
Zhang, Yuanchao;
Zhao, Ping;
Huang, Shiew-Mei

Publication type:

Article

A Review of Imaging Agent Development.

Published in:

AAPS Journal, 2009, v. 11, n. 2, p. 286, doi. 10.1208/s12248-009-9104-5

By:

Agdeppa, Eric;
Spilker, Mary

Publication type:

Article

Role of Physiological Intestinal Water in Oral Absorption.

Published in:

AAPS Journal, 2009, v. 11, n. 2, p. 277, doi. 10.1208/s12248-009-9087-2

By:

Sutton, Steven

Publication type:

Article

Prediction of Hepatic Clearance in Human From In Vitro Data for Successful Drug Development.

Published in:

AAPS Journal, 2009, v. 11, n. 2, p. 262, doi. 10.1208/s12248-009-9103-6

By:

Chiba, Masato;
Ishii, Yasuyuki;
Sugiyama, Yuichi

Publication type:

Article

Effects of Drug Transporters on Volume of Distribution.

Published in:

AAPS Journal, 2009, v. 11, n. 2, p. 250, doi. 10.1208/s12248-009-9102-7

By:

Grover, Anita;
Benet, Leslie

Publication type:

Article

Population-Based Mechanistic Prediction of Oral Drug Absorption.

Published in:

AAPS Journal, 2009, v. 11, n. 2, p. 225, doi. 10.1208/s12248-009-9099-y

By:

Jamei, Masoud;
Turner, David;
Yang, Jiansong;
Neuhoff, Sibylle;
Polak, Sebastian;
Rostami-Hodjegan, Amin;
Tucker, Geoffrey

Publication type:

Article

Therapeutic Paint of Cidofovir/Sucralfate Gel Combination Topically Administered by Spraying for Treatment of orf virus Infections.

Published in:

AAPS Journal, 2009, v. 11, n. 2, p. 242, doi. 10.1208/s12248-009-9101-8

By:

Sonvico, Fabio;
Colombo, Gaia;
Gallina, Laura;
Bortolotti, Fabrizio;
Rossi, Alessandra;
McInnes, Colin;
Massimo, Gina;
Colombo, Paolo;
Scagliarini, Alessandra

Publication type:

Article

Mechanistic Approaches to Predicting Oral Drug Absorption.

Published in:

AAPS Journal, 2009, v. 11, n. 2, p. 217, doi. 10.1208/s12248-009-9098-z

By:

Huang, Weili;
Lee, Sau;
Yu, Lawrence

Publication type:

Article

Workshop Report and Follow-Up—AAPS Workshop on Current Topics in GLP Bioanalysis: Assay Reproducibility for Incurred Samples—Implications of Crystal City Recommendations.

Published in:

2009

By:

Fast, Douglas;
Kelley, Marian;
Viswanathan, C.;
O’Shaughnessy, Jacqueline;
King, S.;
Chaudhary, Ajai;
Weiner, Russell;
DeStefano, Anthony;
Tang, Daniel

Publication type:

Report

A Multi-Tiered Analytical Approach For the Analysis and Quantitation of High-Molecular-Weight Aggregates in a Recombinant Therapeutic Glycoprotein.

Published in:

AAPS Journal, 2009, v. 11, n. 2, p. 335, doi. 10.1208/s12248-009-9108-1

By:

Hughes, Heather;
Morgan, Charles;
Brunyak, Elizabeth;
Barranco, Kristen;
Cohen, Emily;
Edmunds, Tim;
Lee, Karen

Publication type:

Article