Works matching IS 15449173 AND DT 2021 AND VI 19 AND IP 4

Results: 33

HMGCR inhibition stabilizes the glycolytic enzyme PKM2 to support the growth of renal cell carcinoma.
Published in:
PLoS Biology, 2021, v. 19, n. 4, p. 1, doi. 10.1371/journal.pbio.3001197
By:
- Huang, Jiajun;
- Zhao, Xiaoyu;
- Li, Xiang;
- Peng, Jiwei;
- Yang, Weihao;
- Mi, Shengli
Publication type:
Article
Cryo-electron microscopy structures of the N501Y SARS-CoV-2 spike protein in complex with ACE2 and 2 potent neutralizing antibodies.
Published in:
PLoS Biology, 2021, v. 19, n. 4, p. 1, doi. 10.1371/journal.pbio.3001237
By:
- Zhu, Xing;
- Mannar, Dhiraj;
- Srivastava, Shanti S.;
- Berezuk, Alison M.;
- Demers, Jean-Philippe;
- Saville, James W.;
- Leopold, Karoline;
- Li, Wei;
- Dimitrov, Dimiter S.;
- Tuttle, Katharine S.;
- Zhou, Steven;
- Chittori, Sagar;
- Subramaniam, Sriram
Publication type:
Article
Pathogenic missense protein variants affect different functional pathways and proteomic features than healthy population variants.
Published in:
PLoS Biology, 2021, v. 19, n. 4, p. 1, doi. 10.1371/journal.pbio.3001207
By:
- Laddach, Anna;
- Ng, Joseph Chi Fung;
- Fraternali, Franca
Publication type:
Article
Phe-Gly motifs drive fibrillization of TDP-43's prion-like domain condensates.
Published in:
PLoS Biology, 2021, v. 19, n. 4, p. 1, doi. 10.1371/journal.pbio.3001198
By:
- Pantoja-Uceda, David;
- Stuani, Cristiana;
- Laurents, Douglas V.;
- McDermott, Ann E.;
- Buratti, Emanuele;
- Mompeán, Miguel
Publication type:
Article
The mysterious ecosystem at the ocean's surface.
Published in:
PLoS Biology, 2021, v. 19, n. 4, p. 1, doi. 10.1371/journal.pbio.3001046
By:
- Helm, Rebecca R.
Publication type:
Article
The structure of MgtE in the absence of magnesium provides new insights into channel gating.
Published in:
PLoS Biology, 2021, v. 19, n. 4, p. 1, doi. 10.1371/journal.pbio.3001231
By:
- Jin, Fei;
- Sun, Minxuan;
- Fujii, Takashi;
- Yamada, Yurika;
- Wang, Jin;
- Maturana, Andrés D.;
- Wada, Miki;
- Su, Shichen;
- Ma, Jinbiao;
- Takeda, Hironori;
- Kusakizako, Tsukasa;
- Tomita, Atsuhiro;
- Nakada-Nakura, Yoshiko;
- Liu, Kehong;
- Uemura, Tomoko;
- Nomura, Yayoi;
- Nomura, Norimichi;
- Ito, Koichi;
- Nureki, Osamu;
- Namba, Keiichi
Publication type:
Article
Validation testing to determine the sensitivity of lateral flow testing for asymptomatic SARS-CoV-2 detection in low prevalence settings: Testing frequency and public health messaging is key.
Published in:
PLoS Biology, 2021, v. 19, n. 4, p. 1, doi. 10.1371/journal.pbio.3001216
By:
- Ferguson, Jack;
- Dunn, Steven;
- Best, Angus;
- Mirza, Jeremy;
- Percival, Benita;
- Mayhew, Megan;
- Megram, Oliver;
- Ashford, Fiona;
- White, Thomas;
- Moles-Garcia, Emma;
- Crawford, Liam;
- Plant, Tim;
- Bosworth, Andrew;
- Kidd, Michael;
- Richter, Alex;
- Deeks, Jonathan;
- McNally, Alan
Publication type:
Article
Incorporating equity, diversity, and inclusiveness into the Hong Kong Principles.
Published in:
2021
By:
- Moher, David;
- Bouter, Lex;
- Foeger, Nicole;
- Dirnagl, Ulrich
Publication type:
Letter
Gender, diversity, and the responsible assessment of researchers.
Published in:
2021
By:
- Labib, Krishma;
- Evans, Natalie
Publication type:
Letter
Receptor-mediated yolk uptake is required for oskar mRNA localization and cortical anchorage of germ plasm components in the Drosophila oocyte.
Published in:
PLoS Biology, 2021, v. 19, n. 4, p. 1, doi. 10.1371/journal.pbio.3001183
By:
- Tanaka, Tsubasa;
- Tani, Naoki;
- Nakamura, Akira
Publication type:
Article
The first few days of a SARS-CoV-2 infection viewed at single-cell resolution.
Published in:
PLoS Biology, 2021, v. 19, n. 4, p. 1, doi. 10.1371/journal.pbio.3001217
By:
- Gallagher, Tom;
- McCray, Paul B.
Publication type:
Article
Farnesyl pyrophosphate is a new danger signal inducing acute cell death.
Published in:
PLoS Biology, 2021, v. 19, n. 4, p. 1, doi. 10.1371/journal.pbio.3001134
By:
- Chen, Jing;
- Zhang, Xiaochen;
- Li, Liping;
- Ma, Xianqiang;
- Yang, Chunxiao;
- Liu, Zhaodi;
- Li, Chenyang;
- Fernandez-Cabezudo, Maria J.;
- al-Ramadi, Basel K.;
- Wu, Chuan;
- Huang, Weishan;
- Zhang, Yong;
- Zhang, Yonghui;
- Liu, Wanli
Publication type:
Article
The dominantly expressed class II molecule from a resistant MHC haplotype presents only a few Marek's disease virus peptides by using an unprecedented binding motif.
Published in:
PLoS Biology, 2021, v. 19, n. 4, p. 1, doi. 10.1371/journal.pbio.3001057
By:
- Halabi, Samer;
- Ghosh, Michael;
- Stevanović, Stefan;
- Rammensee, Hans-Georg;
- Bertzbach, Luca D.;
- Kaufer, Benedikt B.;
- Moncrieffe, Martin C.;
- Kaspers, Bernd;
- Härtle, Sonja;
- Kaufman, Jim
Publication type:
Article
DAF-16/FoxO and DAF-12/VDR control cellular plasticity both cell-autonomously and via interorgan signaling.
Published in:
PLoS Biology, 2021, v. 19, n. 4, p. 1, doi. 10.1371/journal.pbio.3001204
By:
- Aghayeva, Ulkar;
- Bhattacharya, Abhishek;
- Sural, Surojit;
- Jaeger, Eliza;
- Churgin, Matthew;
- Fang-Yen, Christopher;
- Hobert, Oliver
Publication type:
Article
The dinucleotide composition of the Zika virus genome is shaped by conflicting evolutionary pressures in mammalian hosts and mosquito vectors.
Published in:
PLoS Biology, 2021, v. 19, n. 4, p. 1, doi. 10.1371/journal.pbio.3001201
By:
- Fros, Jelke J.;
- Visser, Imke;
- Tang, Bing;
- Yan, Kexin;
- Nakayama, Eri;
- Visser, Tessa M.;
- Koenraadt, Constantianus J. M.;
- van Oers, Monique M.;
- Pijlman, Gorben P.;
- Suhrbier, Andreas;
- Simmonds, Peter
Publication type:
Article
PD-L1 signaling on human memory CD4+ T cells induces a regulatory phenotype.
Published in:
PLoS Biology, 2021, v. 19, n. 4, p. 1, doi. 10.1371/journal.pbio.3001199
By:
- Fanelli, Giorgia;
- Romano, Marco;
- Nova-Lamperti, Estefania;
- Werner Sunderland, Mariana;
- Nerviani, Alessandra;
- Scottà, Cristiano;
- Bombardieri, Michele;
- Quezada, Sergio A.;
- Sacks, Steven H.;
- Noelle, Randolph J.;
- Pitzalis, Costantino;
- Lechler, Robert I.;
- Lombardi, Giovanna;
- Becker, Pablo D.
Publication type:
Article
A functional bacteria-derived restriction modification system in the mitochondrion of a heterotrophic protist.
Published in:
PLoS Biology, 2021, v. 19, n. 4, p. 1, doi. 10.1371/journal.pbio.3001126
By:
- Milner, David S.;
- Wideman, Jeremy G.;
- Stairs, Courtney W.;
- Dunn, Cory D.;
- Richards, Thomas A.
Publication type:
Article
Smoothened transduces hedgehog signals via activity-dependent sequestration of PKA catalytic subunits.
Published in:
PLoS Biology, 2021, v. 19, n. 4, p. 1, doi. 10.1371/journal.pbio.3001191
By:
- Arveseth, Corvin D.;
- Happ, John T.;
- Hedeen, Danielle S.;
- Zhu, Ju-Fen;
- Capener, Jacob L.;
- Klatt Shaw, Dana;
- Deshpande, Ishan;
- Liang, Jiahao;
- Xu, Jiewei;
- Stubben, Sara L.;
- Nelson, Isaac B.;
- Walker, Madison F.;
- Kawakami, Kouki;
- Inoue, Asuka;
- Krogan, Nevan J.;
- Grunwald, David J.;
- Hüttenhain, Ruth;
- Manglik, Aashish;
- Myers, Benjamin R.
Publication type:
Article
Evaluation of COVID-19 vaccination strategies with a delayed second dose.
Published in:
PLoS Biology, 2021, v. 19, n. 4, p. 1, doi. 10.1371/journal.pbio.3001211
By:
- Moghadas, Seyed M.;
- Vilches, Thomas N.;
- Zhang, Kevin;
- Nourbakhsh, Shokoofeh;
- Sah, Pratha;
- Fitzpatrick, Meagan C.;
- Galvani, Alison P.
Publication type:
Article
How accurately can we assess zoonotic risk?
Published in:
PLoS Biology, 2021, v. 19, n. 4, p. 1, doi. 10.1371/journal.pbio.3001135
By:
- Wille, Michelle;
- Geoghegan, Jemma L.;
- Holmes, Edward C.
Publication type:
Article
Avoiding organelle mutational meltdown across eukaryotes with or without a germline bottleneck.
Published in:
PLoS Biology, 2021, v. 19, n. 4, p. 1, doi. 10.1371/journal.pbio.3001153
By:
- Edwards, David M.;
- Røyrvik, Ellen C.;
- Chustecki, Joanna M.;
- Giannakis, Konstantinos;
- Glastad, Robert C.;
- Radzvilavicius, Arunas L.;
- Johnston, Iain G.
Publication type:
Article
Bacterial persisters are a stochastically formed subpopulation of low-energy cells.
Published in:
PLoS Biology, 2021, v. 19, n. 4, p. 1, doi. 10.1371/journal.pbio.3001194
By:
- Manuse, Sylvie;
- Shan, Yue;
- Canas-Duarte, Silvia J.;
- Bakshi, Somenath;
- Sun, Wei-Sheng;
- Mori, Hirotada;
- Paulsson, Johan;
- Lewis, Kim
Publication type:
Article
Signatures of optimal codon usage in metabolic genes inform budding yeast ecology.
Published in:
PLoS Biology, 2021, v. 19, n. 4, p. 1, doi. 10.1371/journal.pbio.3001185
By:
- LaBella, Abigail Leavitt;
- Opulente, Dana A.;
- Steenwyk, Jacob L.;
- Hittinger, Chris Todd;
- Rokas, Antonis
Publication type:
Article
The methodological quality of 176,620 randomized controlled trials published between 1966 and 2018 reveals a positive trend but also an urgent need for improvement.
Published in:
PLoS Biology, 2021, v. 19, n. 4, p. 1, doi. 10.1371/journal.pbio.3001162
By:
- Vinkers, Christiaan H.;
- Lamberink, Herm J.;
- Tijdink, Joeri K.;
- Heus, Pauline;
- Bouter, Lex;
- Glasziou, Paul;
- Moher, David;
- Damen, Johanna A.;
- Hooft, Lotty;
- Otte, Willem M.
Publication type:
Article
Quantitative proteome comparison of human hearts with those of model organisms.
Published in:
PLoS Biology, 2021, v. 19, n. 4, p. 1, doi. 10.1371/journal.pbio.3001144
By:
- Linscheid, Nora;
- Santos, Alberto;
- Poulsen, Pi Camilla;
- Mills, Robert W.;
- Calloe, Kirstine;
- Leurs, Ulrike;
- Ye, Johan Z.;
- Stolte, Christian;
- Thomsen, Morten B.;
- Bentzen, Bo H.;
- Lundegaard, Pia R.;
- Olesen, Morten S.;
- Jensen, Lars J.;
- Olsen, Jesper V.;
- Lundby, Alicia
Publication type:
Article
Neurocognitive processing efficiency for discriminating human non-alarm rather than alarm scream calls.
Published in:
PLoS Biology, 2021, v. 19, n. 4, p. 1, doi. 10.1371/journal.pbio.3000751
By:
- Frühholz, Sascha;
- Dietziker, Joris;
- Staib, Matthias;
- Trost, Wiebke
Publication type:
Article
Peroxiredoxin alleviates the fitness costs of imidacloprid resistance in an insect pest of rice.
Published in:
PLoS Biology, 2021, v. 19, n. 4, p. 1, doi. 10.1371/journal.pbio.3001190
By:
- Pang, Rui;
- Xing, Ke;
- Yuan, Longyu;
- Liang, Zhikun;
- Chen, Meng;
- Yue, Xiangzhao;
- Dong, Yi;
- Ling, Yan;
- He, Xionglei;
- Li, Xianchun;
- Zhang, Wenqing
Publication type:
Article
Molecular basis of F-actin regulation and sarcomere assembly via myotilin.
Published in:
PLoS Biology, 2021, v. 19, n. 4, p. 1, doi. 10.1371/journal.pbio.3001148
By:
- Kostan, Julius;
- Pavšič, Miha;
- Puž, Vid;
- Schwarz, Thomas C.;
- Drepper, Friedel;
- Molt, Sibylle;
- Graewert, Melissa Ann;
- Schreiner, Claudia;
- Sajko, Sara;
- van der Ven, Peter F. M.;
- Onipe, Adekunle;
- Svergun, Dmitri I.;
- Warscheid, Bettina;
- Konrat, Robert;
- Fürst, Dieter O.;
- Lenarčič, Brigita;
- Djinović-Carugo, Kristina
Publication type:
Article
Neural stem cells traffic functional mitochondria via extracellular vesicles.
Published in:
PLoS Biology, 2021, v. 19, n. 4, p. 1, doi. 10.1371/journal.pbio.3001166
By:
- Peruzzotti-Jametti, Luca;
- Bernstock, Joshua D.;
- Willis, Cory M.;
- Manferrari, Giulia;
- Rogall, Rebecca;
- Fernandez-Vizarra, Erika;
- Williamson, James C.;
- Braga, Alice;
- van den Bosch, Aletta;
- Leonardi, Tommaso;
- Krzak, Grzegorz;
- Kittel, Ágnes;
- Benincá, Cristiane;
- Vicario, Nunzio;
- Tan, Sisareuth;
- Bastos, Carlos;
- Bicci, Iacopo;
- Iraci, Nunzio;
- Smith, Jayden A.;
- Peacock, Ben
Publication type:
Article
Human protection drives the emergence of a new coping style in animals.
Published in:
PLoS Biology, 2021, v. 19, n. 4, p. 1, doi. 10.1371/journal.pbio.3001186
By:
- Sadoul, Bastien;
- Blumstein, Daniel T.;
- Alfonso, Sébastien;
- Geffroy, Benjamin
Publication type:
Article
The evolving role of preprints in the dissemination of COVID-19 research and their impact on the science communication landscape.
Published in:
PLoS Biology, 2021, v. 19, n. 4, p. 1, doi. 10.1371/journal.pbio.3000959
By:
- Fraser, Nicholas;
- Brierley, Liam;
- Dey, Gautam;
- Polka, Jessica K.;
- Pálfy, Máté;
- Nanni, Federico;
- Coates, Jonathon Alexis
Publication type:
Article
Stress and odorant receptor feedback during a critical period after hatching regulates olfactory sensory neuron differentiation in Drosophila.
Published in:
PLoS Biology, 2021, v. 19, n. 4, p. 1, doi. 10.1371/journal.pbio.3001101
By:
- Jafari, Shadi;
- Henriksson, Johan;
- Yan, Hua;
- Alenius, Mattias
Publication type:
Article
Anesthetics fragment hippocampal network activity, alter spine dynamics, and affect memory consolidation.
Published in:
PLoS Biology, 2021, v. 19, n. 4, p. 1, doi. 10.1371/journal.pbio.3001146
By:
- Yang, Wei;
- Chini, Mattia;
- Pöpplau, Jastyn A.;
- Formozov, Andrey;
- Dieter, Alexander;
- Piechocinski, Patrick;
- Rais, Cynthia;
- Morellini, Fabio;
- Sporns, Olaf;
- Hanganu-Opatz, Ileana L.;
- Wiegert, J. Simon
Publication type:
Article