Works matching IS 15250016 AND DT 2015 AND VI 23 AND IP 4

Results: 27

Broad Functional Correction of Molecular Impairments by Systemic Delivery of scAAVrh74-hSGSH Gene Delivery in MPS IIIA Mice.

Published in:

Molecular Therapy, 2015, v. 23, n. 4, p. 638, doi. 10.1038/mt.2015.9

By:

Duncan, F Jason;
Naughton, Bartholomew J;
Zaraspe, Kimberly;
Murrey, Darren A;
Meadows, Aaron S;
Clark, Kelly Reed;
Newsom, David E;
White, Peter;
Fu, Haiyan;
McCarty, Douglas M

Publication type:

Article

Cell Cycle Status of CD34+ Hemopoietic Stem Cells Determines Lentiviral Integration in Actively Transcribed and Development-related Genes.

Published in:

Molecular Therapy, 2015, v. 23, n. 4, p. 683, doi. 10.1038/mt.2014.246

By:

Papanikolaou, Eleni;
Paruzynski, Anna;
Kasampalidis, Ioannis;
Deichmann, Annette;
Stamateris, Evangelos;
Schmidt, Manfred;
von Kalle, Christof;
Anagnou, Nicholas P

Publication type:

Article

From the Impact Factor to DORA and the Scientific Content of Articles.

Published in:

Molecular Therapy, 2015, v. 23, n. 4, p. 609, doi. 10.1038/mt.2015.32

By:

Ylä-Herttuala, Seppo

Publication type:

Article

Perforin Gene Transfer Into Hematopoietic Stem Cells Improves Immune Dysregulation in Murine Models of Perforin Deficiency.

Published in:

Molecular Therapy, 2015, v. 23, n. 4, p. 737, doi. 10.1038/mt.2014.242

By:

Carmo, Marlene;
Risma, Kimberly A;
Arumugam, Paritha;
Tiwari, Swati;
Hontz, Adrianne E;
Montiel-Equihua, Claudia A;
Alonso-Ferrero, Maria E;
Blundell, Michael P;
Schambach, Axel;
Baum, Christopher;
Malik, Punam;
Thrasher, Adrian J;
Jordan, Michael B;
Gaspar, H Bobby

Publication type:

Article

Antiobesity Strategy Targets Energy Economy Safeguards.

Published in:

Molecular Therapy, 2015, v. 23, n. 4, p. 615, doi. 10.1038/mt.2015.39

By:

Vivaudou, Michel;
Terzic, André

Publication type:

Article

The Clinical Relevance of the miR-197/CKS1B/STAT3-mediated PD-L1 Network in Chemoresistant Non-small-cell Lung Cancer.

Published in:

Molecular Therapy, 2015, v. 23, n. 4, p. 717, doi. 10.1038/mt.2015.10

By:

Fujita, Yu;
Yagishita, Shigehiro;
Hagiwara, Keitaro;
Yoshioka, Yusuke;
Kosaka, Nobuyoshi;
Takeshita, Fumitaka;
Fujiwara, Tomohiro;
Tsuta, Koji;
Nokihara, Hiroshi;
Tamura, Tomohide;
Asamura, Hisao;
Kawaishi, Makoto;
Kuwano, Kazuyoshi;
Ochiya, Takahiro

Publication type:

Article

In vivo secretion of anti-CD3 × anti-tumor bispecific antibodies by gene-modified cells: over a decade of T-cell engagement.

Published in:

Molecular Therapy, 2015, v. 23, n. 4, p. 612, doi. 10.1038/mt.2015.36

By:

Compte, Marta;
Sanz, Laura;
Álvarez-Vallina, Luis

Publication type:

Article

Paracrine Factors of Human Fetal MSCs Inhibit Liver Cancer Growth Through Reduced Activation of IGF-1R/PI3K/Akt Signaling.

Published in:

Molecular Therapy, 2015, v. 23, n. 4, p. 746, doi. 10.1038/mt.2015.13

By:

Yulyana, Yulyana;
Ho, Ivy A W;
Sia, Kian Chuan;
Newman, Jennifer P;
Toh, Xin Yi;
Endaya, Berwini B;
Chan, Jerry K Y;
Gnecchi, Massimiliano;
Huynh, Hung;
Chung, Alexander Y F;
Lim, Kiat Hon;
Leong, Hui Sun;
Iyer, Narayanan Gopalakrishna;
Hui, Kam Man;
Lam, Paula Y P

Publication type:

Article

Enhancing Antitumor Efficacy of Chimeric Antigen Receptor T Cells Through Constitutive CD40L Expression.

Published in:

Molecular Therapy, 2015, v. 23, n. 4, p. 769, doi. 10.1038/mt.2015.4

By:

Curran, Kevin J;
Seinstra, Beatrijs A;
Nikhamin, Yan;
Yeh, Raymond;
Usachenko, Yelena;
van Leeuwen, Dayenne G;
Purdon, Terence;
Pegram, Hollie J;
Brentjens, Renier J

Publication type:

Article

Corrigendum to 'CD133-targeted Gene Transfer Into Long-term Repopulating Hematopoietic Stem Cells'.

Published in:: Molecular Therapy, 2015, v. 23, n. 4, p. 790, doi. 10.1038/mt.2015.26
Publication type:: Article

A Shot in the Bone Corrects a Genetic Disease.

Published in:

Molecular Therapy, 2015, v. 23, n. 4, p. 614, doi. 10.1038/mt.2015.38

By:

Brown, Brian D

Publication type:

Article

Corrigendum to 'Let-7 microRNAs Regenerate Peripheral Nerve Regeneration by Targeting Nerve Growth Factor'.

Published in:: Molecular Therapy, 2015, v. 23, n. 4, p. 790, doi. 10.1038/mt.2014.255
Publication type:: Article

Response to 'In vivo secretion of anti-CD3 × anti-tumor bispecific antibodies by gene-modified cells: over a decade of T-cell engagement'.

Published in:

Molecular Therapy, 2015, v. 23, n. 4, p. 613, doi. 10.1038/mt.2015.37

By:

Iwahori, Kota;
Song, Xiao-Tong;
Gottschalk, Stephen

Publication type:

Article

Transduction of antigen-presenting cells in the brain by AAV9 warrants caution in preclinical studies.

Published in:

Molecular Therapy, 2015, v. 23, n. 4, p. 612, doi. 10.1038/mt.2015.35

By:

Forsayeth, John;
Bankiewicz, Krystof S

Publication type:

Article

Characterization of a Bispecific FLT3 X CD3 Antibody in an Improved, Recombinant Format for the Treatment of Leukemia.

Published in:

Molecular Therapy, 2015, v. 23, n. 4, p. 648, doi. 10.1038/mt.2015.2

By:

Durben, Michael;
Schmiedel, Dominik;
Hofmann, Martin;
Vogt, Fabian;
Nübling, Tina;
Pyz, Elwira;
Bühring, Hans-Jörg;
Rammensee, Hans-Georg;
Salih, Helmut R;
Große-Hovest, Ludger;
Jung, Gundram

Publication type:

Article

PET Imaging of Oncolytic VSV Expressing the Mutant HSV-1 Thymidine Kinase Transgene in a Preclinical HCC Rat Model.

Published in:

Molecular Therapy, 2015, v. 23, n. 4, p. 728, doi. 10.1038/mt.2015.12

By:

Muñoz-Álvarez, Kim A;
Altomonte, Jennifer;
Laitinen, Iina;
Ziegler, Sibylle;
Steiger, Katja;
Esposito, Irene;
Schmid, Roland M;
Ebert, Oliver

Publication type:

Article

HDAC Inhibitors Target HDAC5, Upregulate MicroRNA-125a-5p, and Induce Apoptosis in Breast Cancer Cells.

Published in:

Molecular Therapy, 2015, v. 23, n. 4, p. 656, doi. 10.1038/mt.2014.247

By:

Hsieh, Tsung-Hua;
Hsu, Chia-Yi;
Tsai, Cheng-Fang;
Long, Cheng-Yu;
Wu, Chin-Hu;
Wu, Deng-Chyang;
Lee, Jau-Nan;
Chang, Wei-Chun;
Tsai, Eing-Mei

Publication type:

Article

Disruption of KATP Channel Expression in Skeletal Muscle by Targeted Oligonucleotide Delivery Promotes Activity-linked Thermogenesis.

Published in:

Molecular Therapy, 2015, v. 23, n. 4, p. 707, doi. 10.1038/mt.2015.21

By:

Koganti, Siva Rama Krishna;
Zhu, Zhiyong;
Subbotina, Ekaterina;
Gao, Zhan;
Sierra, Ana;
Proenza, Manuel;
Yang, Liping;
Alekseev, Alexey;
Hodgson-Zingman, Denice;
Zingman, Leonid

Publication type:

Article

Intrinsic Transgene Immunogenicity Gears CD8+ T-cell Priming After rAAV-Mediated Muscle Gene Transfer.

Published in:

Molecular Therapy, 2015, v. 23, n. 4, p. 697, doi. 10.1038/mt.2014.235

By:

Carpentier, Maxime;
Lorain, Stéphanie;
Chappert, Pascal;
Lalfer, Mélanie;
Hardet, Romain;
Urbain, Dominique;
Peccate, Cécile;
Adriouch, Sahil;
Garcia, Luis;
Davoust, Jean;
Gross, David-Alexandre

Publication type:

Article

Hybrid Nonviral/Viral Vector Systems for Improved piggyBac DNA Transposon In Vivo Delivery.

Published in:

Molecular Therapy, 2015, v. 23, n. 4, p. 667, doi. 10.1038/mt.2014.254

By:

Cooney, Ashley L;
Singh, Brajesh K;
Sinn, Patrick L

Publication type:

Article

Intraosseous Delivery of Lentiviral Vectors Targeting Factor VIII Expression in Platelets Corrects Murine Hemophilia A.

Published in:

Molecular Therapy, 2015, v. 23, n. 4, p. 617, doi. 10.1038/mt.2015.20

By:

Wang, Xuefeng;
Shin, Simon C;
Chiang, Andy F J;
Khan, Iram;
Pan, Dao;
Rawlings, David J;
Miao, Carol H

Publication type:

Article

High Capsid-Genome Correlation Facilitates Creation of AAV Libraries for Directed Evolution.

Published in:

Molecular Therapy, 2015, v. 23, n. 4, p. 675, doi. 10.1038/mt.2015.3

By:

Nonnenmacher, Mathieu;
van Bakel, Harm;
Hajjar, Roger J;
Weber, Thomas

Publication type:

Article

Research Highlights.

Published in:: Molecular Therapy, 2015, v. 23, n. 4, p. 611, doi. 10.1038/mt.2015.34
Publication type:: Article

Intra-Amniotic rAAV-Mediated Microdystrophin Gene Transfer Improves Canine X-Linked Muscular Dystrophy and May Induce Immune Tolerance.

Published in:

Molecular Therapy, 2015, v. 23, n. 4, p. 627, doi. 10.1038/mt.2015.5

By:

Hayashita-Kinoh, Hiromi;
Yugeta, Naoko;
Okada, Hironori;
Nitahara-Kasahara, Yuko;
Chiyo, Tomoko;
Okada, Takashi;
Takeda, Shin'ichi

Publication type:

Article

In This Issue.

Published in:: Molecular Therapy, 2015, v. 23, n. 4, p. 610, doi. 10.1038/mt.2015.33
Publication type:: Article

Chimeric Antigen Receptors With Mutated IgG4 Fc Spacer Avoid Fc Receptor Binding and Improve T Cell Persistence and Antitumor Efficacy.

Published in:

Molecular Therapy, 2015, v. 23, n. 4, p. 757, doi. 10.1038/mt.2014.208

By:

Jonnalagadda, Mahesh;
Mardiros, Armen;
Urak, Ryan;
Wang, Xiuli;
Hoffman, Lauren J;
Bernanke, Alyssa;
Chang, Wen-Chung;
Bretzlaff, William;
Starr, Renate;
Priceman, Saul;
Ostberg, Julie R;
Forman, Stephen J;
Brown, Christine E

Publication type:

Article

First-in-man Phase 1 Clinical Trial of Gene Therapy for Advanced Pancreatic Cancer: Safety, Biodistribution, and Preliminary Clinical Findings.

Published in:

Molecular Therapy, 2015, v. 23, n. 4, p. 779, doi. 10.1038/mt.2015.1

By:

Buscail, Louis;
Bournet, Barbara;
Vernejoul, Fabienne;
Cambois, Gilles;
Lulka, Hubert;
Hanoun, Naïma;
Dufresne, Marlène;
Meulle, Aline;
Vignolle-Vidoni, Alix;
Ligat, Laetitia;
Saint-Laurent, Nathalie;
Pont, Frédéric;
Dejean, Sébastien;
Gayral, Marion;
Martins, Frédéric;
Torrisani, Jérôme;
Barbey, Odile;
Gross, Fabian;
Guimbaud, Rosine;
Otal, Philippe

Publication type:

Article

Works matching IS 15250016 AND DT 2015 AND VI 23 AND IP 4

Broad Functional Correction of Molecular Impairments by Systemic Delivery of scAAVrh74-hSGSH Gene Delivery in MPS IIIA Mice.

Cell Cycle Status of CD34<sup>+</sup> Hemopoietic Stem Cells Determines Lentiviral Integration in Actively Transcribed and Development-related Genes.

From the Impact Factor to DORA and the Scientific Content of Articles.

Perforin Gene Transfer Into Hematopoietic Stem Cells Improves Immune Dysregulation in Murine Models of Perforin Deficiency.

Antiobesity Strategy Targets Energy Economy Safeguards.

The Clinical Relevance of the miR-197/CKS1B/STAT3-mediated PD-L1 Network in Chemoresistant Non-small-cell Lung Cancer.

In vivo secretion of anti-CD3 × anti-tumor bispecific antibodies by gene-modified cells: over a decade of T-cell engagement.

Paracrine Factors of Human Fetal MSCs Inhibit Liver Cancer Growth Through Reduced Activation of IGF-1R/PI3K/Akt Signaling.

Enhancing Antitumor Efficacy of Chimeric Antigen Receptor T Cells Through Constitutive CD40L Expression.

Corrigendum to 'CD133-targeted Gene Transfer Into Long-term Repopulating Hematopoietic Stem Cells'.

A Shot in the Bone Corrects a Genetic Disease.

Corrigendum to 'Let-7 microRNAs Regenerate Peripheral Nerve Regeneration by Targeting Nerve Growth Factor'.

Response to 'In vivo secretion of anti-CD3 × anti-tumor bispecific antibodies by gene-modified cells: over a decade of T-cell engagement'.

Transduction of antigen-presenting cells in the brain by AAV9 warrants caution in preclinical studies.

Characterization of a Bispecific FLT3 X CD3 Antibody in an Improved, Recombinant Format for the Treatment of Leukemia.

PET Imaging of Oncolytic VSV Expressing the Mutant HSV-1 Thymidine Kinase Transgene in a Preclinical HCC Rat Model.

HDAC Inhibitors Target HDAC5, Upregulate MicroRNA-125a-5p, and Induce Apoptosis in Breast Cancer Cells.

Disruption of K<sub>ATP</sub> Channel Expression in Skeletal Muscle by Targeted Oligonucleotide Delivery Promotes Activity-linked Thermogenesis.

Intrinsic Transgene Immunogenicity Gears CD8<sup>+</sup> T-cell Priming After rAAV-Mediated Muscle Gene Transfer.

Hybrid Nonviral/Viral Vector Systems for Improved piggyBac DNA Transposon In Vivo Delivery.

Intraosseous Delivery of Lentiviral Vectors Targeting Factor VIII Expression in Platelets Corrects Murine Hemophilia A.

High Capsid-Genome Correlation Facilitates Creation of AAV Libraries for Directed Evolution.

Research Highlights.

Intra-Amniotic rAAV-Mediated Microdystrophin Gene Transfer Improves Canine X-Linked Muscular Dystrophy and May Induce Immune Tolerance.

In This Issue.

Chimeric Antigen Receptors With Mutated IgG4 Fc Spacer Avoid Fc Receptor Binding and Improve T Cell Persistence and Antitumor Efficacy.

First-in-man Phase 1 Clinical Trial of Gene Therapy for Advanced Pancreatic Cancer: Safety, Biodistribution, and Preliminary Clinical Findings.