Works matching IS 15250016 AND DT 2015 AND VI 23

Results: 214

In This Issue.

Published in:: Molecular Therapy, 2015, v. 23, n. 10, p. 1554, doi. 10.1038/mt.2015.159
Publication type:: Article

Respiratory Syncytial Virus Utilizes a tRNA Fragment to Suppress Antiviral Responses Through a Novel Targeting Mechanism.

Published in:

Molecular Therapy, 2015, v. 23, n. 10, p. 1622, doi. 10.1038/mt.2015.124

By:

Deng, Junfang;
Ptashkin, Ryan N;
Chen, Yu;
Cheng, Zhi;
Liu, Guangliang;
Phan, Thien;
Deng, Xiaoling;
Zhou, Jiehua;
Lee, Inhan;
Lee, Yong Sun;
Bao, Xiaoyong

Publication type:

Article

Gene Therapy for Heart Failure: Back to the Bench.

Published in:

Molecular Therapy, 2015, v. 23, n. 10, p. 1551, doi. 10.1038/mt.2015.158

By:

Ylä-Herttuala, Seppo

Publication type:

Article

MitoTALEN: A General Approach to Reduce Mutant mtDNA Loads and Restore Oxidative Phosphorylation Function in Mitochondrial Diseases.

Published in:

Molecular Therapy, 2015, v. 23, n. 10, p. 1592, doi. 10.1038/mt.2015.126

By:

Hashimoto, Masami;
Bacman, Sandra R;
Peralta, Susana;
Falk, Marni J;
Chomyn, Anne;
Chan, David C;
Williams, Sion L;
Moraes, Carlos T

Publication type:

Article

Emerging Roles of tRNA-derived Fragments in Viral Infections: The Case of Respiratory Syncytial Virus.

Published in:

Molecular Therapy, 2015, v. 23, n. 10, p. 1557, doi. 10.1038/mt.2015.161

By:

Ivanov, Pavel

Publication type:

Article

Riboswitch-mediated Attenuation of Transgene Cytotoxicity Increases Adeno-associated Virus Vector Yields in HEK-293 Cells.

Published in:

Molecular Therapy, 2015, v. 23, n. 10, p. 1582, doi. 10.1038/mt.2015.123

By:

Strobel, Benjamin;
Klauser, Benedikt;
Hartig, Jörg S;
Lamla, Thorsten;
Gantner, Florian;
Kreuz, Sebastian

Publication type:

Article

Erratum to 'Hyperactive PiggyBac Transposons for Sustained and Robust Liver-targeted Gene Therapy'.

Published in:: Molecular Therapy, 2015, v. 23, n. 10, p. 1671, doi. 10.1038/mt.2015.132
Publication type:: Article

Dual TNF-α/IL-12p40 Interference as a Strategy to Protect Against Colitis Based on miR-16 Precursors With Macrophage Targeting Vectors.

Published in:

Molecular Therapy, 2015, v. 23, n. 10, p. 1611, doi. 10.1038/mt.2015.111

By:

Huang, Zhen;
Ma, Junting;
Chen, Mengjie;
Jiang, Haoyang;
Fu, Yong;
Gan, Jingjing;
Dong, Lei;
Zhang, Junfeng;
Chen, Jiangning

Publication type:

Article

Strain-dependent Lethal Toxicity in NKG2D Ligand-targeted CAR T-cell Therapy.

Published in:

Molecular Therapy, 2015, v. 23, n. 10, p. 1559, doi. 10.1038/mt.2015.162

By:

Lynn, Rachel C;
Powell, Daniel J

Publication type:

Article

Ubiquitin-like Molecule ISG15 Acts as an Immune Adjuvant to Enhance Antigen-specific CD8 T-cell Tumor Immunity.

Published in:

Molecular Therapy, 2015, v. 23, n. 10, p. 1653, doi. 10.1038/mt.2015.120

By:

Villarreal, Daniel O;
Wise, Megan C;
Siefert, Rebekah J;
Yan, Jian;
Wood, Laurence M;
Weiner, David B

Publication type:

Article

Human Rhinovirus Presenting 4E10 Epitope of HIV-1 MPER Elicits Neutralizing Antibodies in Human ICAM-1 Transgenic Mice.

Published in:

Molecular Therapy, 2015, v. 23, n. 10, p. 1663, doi. 10.1038/mt.2015.107

By:

Yi, Guohua;
Tu, Xiongying;
Bharaj, Preeti;
Guo, Hua;
Zhang, Junli;
Shankar, Premlata;
Manjunath, N

Publication type:

Article

Optogenetic Vision Restoration Using Rhodopsin for Enhanced Sensitivity.

Published in:

Molecular Therapy, 2015, v. 23, n. 10, p. 1562, doi. 10.1038/mt.2015.121

By:

Gaub, Benjamin M;
Berry, Michael H;
Holt, Amy E;
Isacoff, Ehud Y;
Flannery, John G

Publication type:

Article

Research Highlights.

Published in:: Molecular Therapy, 2015, v. 23, n. 10, p. 1555, doi. 10.1038/mt.2015.160
Publication type:: Article

Biodistribution Analysis of Oncolytic Adenoviruses in Patient Autopsy Samples Reveals Vascular Transduction of Noninjected Tumors and Tissues.

Published in:

Molecular Therapy, 2015, v. 23, n. 10, p. 1641, doi. 10.1038/mt.2015.125

By:

Koski, Anniina;
Bramante, Simona;
Kipar, Anja;
Oksanen, Minna;
Juhila, Juuso;
Vassilev, Lotta;
Joensuu, Timo;
Kanerva, Anna;
Hemminki, Akseli

Publication type:

Article

Benefits of Neuronal Preferential Systemic Gene Therapy for Neurotransmitter Deficiency.

Published in:

Molecular Therapy, 2015, v. 23, n. 10, p. 1572, doi. 10.1038/mt.2015.122

By:

Lee, Ni-Chung;
Muramatsu, Shin-Ichi;
Chien, Yin-Hsiu;
Liu, Wen-Shin;
Wang, Wei-Hua;
Cheng, Chia-Hao;
Hu, Meng-Kai;
Chen, Pin-Wen;
Tzen, Kai-Yuan;
Byrne, Barry J;
Hwu, Wuh-Liang

Publication type:

Article

T Cells Engineered With Chimeric Antigen Receptors Targeting NKG2D Ligands Display Lethal Toxicity in Mice.

Published in:

Molecular Therapy, 2015, v. 23, n. 10, p. 1600, doi. 10.1038/mt.2015.119

By:

VanSeggelen, Heather;
Hammill, Joanne A;
Dvorkin-Gheva, Anna;
Tantalo, Daniela GM;
Kwiecien, Jacek M;
Denisova, Galina F;
Rabinovich, Brian;
Wan, Yonghong;
Bramson, Jonathan L

Publication type:

Article

Viral Infection of Tumors Overcomes Resistance to PD-1-immunotherapy by Broadening Neoantigenome-directed T-cell Responses.

Published in:

Molecular Therapy, 2015, v. 23, n. 10, p. 1630, doi. 10.1038/mt.2015.115

By:

Woller, Norman;
Gürlevik, Engin;
Fleischmann-Mundt, Bettina;
Schumacher, Anja;
Knocke, Sarah;
Kloos, Arnold M;
Saborowski, Michael;
Geffers, Robert;
Manns, Michael P;
Wirth, Thomas C;
Kubicka, Stefan;
Kühnel, Florian

Publication type:

Article

Case Report of a Fatal Serious Adverse Event Upon Administration of T Cells Transduced With a MART-1-specific T-cell Receptor.

Published in:

Molecular Therapy, 2015, v. 23, n. 9, p. 1541, doi. 10.1038/mt.2015.60

By:

van den Berg, Joost H;
Gomez-Eerland, Raquel;
van de Wiel, Bart;
Hulshoff, Lenie;
van den Broek, Daan;
Bins, Adriaan;
Tan, Hanno L;
Harper, Jane V;
Hassan, Namir J;
Jakobsen, Bent K;
Jorritsma, Annelies;
Blank, Christian U;
Schumacher, Ton N M;
Haanen, John B A G

Publication type:

Article

Sequence-engineered mRNA Without Chemical Nucleoside Modifications Enables an Effective Protein Therapy in Large Animals.

Published in:

Molecular Therapy, 2015, v. 23, n. 9, p. 1456, doi. 10.1038/mt.2015.103

By:

Thess, Andreas;
Grund, Stefanie;
Mui, Barbara L;
Hope, Michael J;
Baumhof, Patrick;
Fotin-Mleczek, Mariola;
Schlake, Thomas

Publication type:

Article

A Multidrug-resistant Engineered CAR T Cell for Allogeneic Combination Immunotherapy.

Published in:

Molecular Therapy, 2015, v. 23, n. 9, p. 1507, doi. 10.1038/mt.2015.104

By:

Valton, Julien;
Guyot, Valérie;
Marechal, Alan;
Filhol, Jean-Marie;
Juillerat, Alexandre;
Duclert, Aymeric;
Duchateau, Philippe;
Poirot, Laurent

Publication type:

Article

Gene Augmentation Therapy Restores Retinal Function and Visual Behavior in a Sheep Model of CNGA3 Achromatopsia.

Published in:

Molecular Therapy, 2015, v. 23, n. 9, p. 1423, doi. 10.1038/mt.2015.114

By:

Banin, Eyal;
Gootwine, Elisha;
Obolensky, Alexey;
Ezra-Elia, Raaya;
Ejzenberg, Ayala;
Zelinger, Lina;
Honig, Hen;
Rosov, Alexander;
Yamin, Esther;
Sharon, Dror;
Averbukh, Edward;
Hauswirth, William W;
Ofri, Ron

Publication type:

Article

Self-Destruct Genetic Switch to Safeguard iPS Cells.

Published in:

Molecular Therapy, 2015, v. 23, n. 9, p. 1417, doi. 10.1038/mt.2015.139

By:

Ivics, Zoltán

Publication type:

Article

Hopx and the Cardiomyocyte Parentage.

Published in:

Molecular Therapy, 2015, v. 23, n. 9, p. 1420, doi. 10.1038/mt.2015.140

By:

Schneider, Michael D;
Baker, Andrew H;
Riley, Paul

Publication type:

Article

Research Highlights.

Published in:: Molecular Therapy, 2015, v. 23, n. 9, p. 1415, doi. 10.1038/mt.2015.137
Publication type:: Article

Mesenchymal Stromal Cells for Linked Delivery of Oncolytic and Apoptotic Adenoviruses to Non-small-cell Lung Cancers.

Published in:

Molecular Therapy, 2015, v. 23, n. 9, p. 1497, doi. 10.1038/mt.2015.110

By:

Hoyos, Valentina;
Del Bufalo, Francesca;
Yagyu, Shigeki;
Ando, Miki;
Dotti, Gianpietro;
Suzuki, Masataka;
Bouchier-Hayes, Lisa;
Alemany, Ramon;
Brenner, Malcolm K

Publication type:

Article

mRNA: Fulfilling the Promise of Gene Therapy.

Published in:

Molecular Therapy, 2015, v. 23, n. 9, p. 1416, doi. 10.1038/mt.2015.138

By:

Weissman, Drew;
Karikó, Katalin

Publication type:

Article

Phase 1b Trial of Biweekly Intravenous Pexa-Vec (JX-594), an Oncolytic and Immunotherapeutic Vaccinia Virus in Colorectal Cancer.

Published in:

Molecular Therapy, 2015, v. 23, n. 9, p. 1532, doi. 10.1038/mt.2015.109

By:

Park, Se Hoon;
Breitbach, Caroline J;
Lee, Jeeyun;
Park, Joon Oh;
Lim, Ho Yeong;
Kang, Won Ki;
Moon, Anne;
Mun, Jae-Hee;
Sommermann, Erica M;
Maruri Avidal, Liliana;
Patt, Rick;
Pelusio, Adina;
Burke, James;
Hwang, Tae-Ho;
Kirn, David;
Park, Young Suk

Publication type:

Article

ACE2 Therapy Using Adeno-associated Viral Vector Inhibits Liver Fibrosis in Mice.

Published in:

Molecular Therapy, 2015, v. 23, n. 9, p. 1434, doi. 10.1038/mt.2015.92

By:

Mak, Kai Y;
Chin, Ruth;
Cunningham, Sharon C;
Habib, Miriam R;
Torresi, Joseph;
Sharland, Alexandra F;
Alexander, Ian E;
Angus, Peter W;
Herath, Chandana B

Publication type:

Article

Arylsulfatase A Overexpressing Human iPSC-derived Neural Cells Reduce CNS Sulfatide Storage in a Mouse Model of Metachromatic Leukodystrophy.

Published in:

Molecular Therapy, 2015, v. 23, n. 9, p. 1519, doi. 10.1038/mt.2015.106

By:

Doerr, Jonas;
Böckenhoff, Annika;
Ewald, Benjamin;
Ladewig, Julia;
Eckhardt, Matthias;
Gieselmann, Volkmar;
Matzner, Ulrich;
Brüstle, Oliver;
Koch, Philipp

Publication type:

Article

Hemophilia Gene Therapy: Caught Between a Cure and an Immune Response.

Published in:

Molecular Therapy, 2015, v. 23, n. 9, p. 1411, doi. 10.1038/mt.2015.135

By:

Herzog, Roland W.

Publication type:

Article

In This Issue.

Published in:: Molecular Therapy, 2015, v. 23, n. 9, p. 1414, doi. 10.1038/mt.2015.136
Publication type:: Article

Tumor Microenvironment Remodeling by 4-Methylumbelliferone Boosts the Antitumor Effect of Combined Immunotherapy in Murine Colorectal Carcinoma.

Published in:

Molecular Therapy, 2015, v. 23, n. 9, p. 1444, doi. 10.1038/mt.2015.112

By:

Malvicini, Mariana;
Fiore, Esteban;
Ghiaccio, Valentina;
Piccioni, Flavia;
Rizzo, Miguel;
Olmedo Bonadeo, Lucila;
García, Mariana;
Rodríguez, Marcelo;
Bayo, Juan;
Peixoto, Estanislao;
Atorrasagasti, Catalina;
Alaniz, Laura;
Aquino, Jorge;
Matar, Pablo;
Mazzolini, Guillermo

Publication type:

Article

Aptamers Selected to Postoperative Lung Adenocarcinoma Detect Circulating Tumor Cells in Human Blood.

Published in:

Molecular Therapy, 2015, v. 23, n. 9, p. 1486, doi. 10.1038/mt.2015.108

By:

Zamay, Galina S;
Kolovskaya, Olga S;
Zamay, Tatiana N;
Glazyrin, Yury E;
Krat, Alexey V;
Zubkova, Olga;
Spivak, Ekaterina;
Wehbe, Mohammed;
Gargaun, Ana;
Muharemagic, Darija;
Komarova, Mariia;
Grigorieva, Valentina;
Savchenko, Andrey;
Modestov, Andrey A;
Berezovski, Maxim V;
Zamay, Anna S

Publication type:

Article

miRNA-embedded shRNAs for Lineage-specific BCL11A Knockdown and Hemoglobin F Induction.

Published in:

Molecular Therapy, 2015, v. 23, n. 9, p. 1465, doi. 10.1038/mt.2015.113

By:

Guda, Swaroopa;
Brendel, Christian;
Renella, Raffaele;
Du, Peng;
Bauer, Daniel E;
Canver, Matthew C;
Grenier, Jennifer K;
Grimson, Andrew W;
Kamran, Sophia C;
Thornton, James;
de Boer, Helen;
Root, David E;
Milsom, Michael D;
Orkin, Stuart H;
Gregory, Richard I;
Williams, David A

Publication type:

Article

An Inducible Caspase-9 Suicide Gene to Improve the Safety of Therapy Using Human Induced Pluripotent Stem Cells.

Published in:

Molecular Therapy, 2015, v. 23, n. 9, p. 1475, doi. 10.1038/mt.2015.100

By:

Yagyu, Shigeki;
Hoyos, Valentina;
Del Bufalo, Francesca;
Brenner, Malcolm K

Publication type:

Article

In This Issue.

Published in:: Molecular Therapy, 2015, v. 23, n. 8, p. 1280, doi. 10.1038/mt.2015.117
Publication type:: Article

Molecular Therapy Special Issue on Gene Editing Technologies and Applications.

Published in:

Molecular Therapy, 2015, v. 23, n. 8, p. 1279, doi. 10.1038/mt.2015.80

By:

Frederickson, Robert;
Ylä-Herttuala, Seppo

Publication type:

Article

Neonatal Systemic AAV Induces Tolerance to CNS Gene Therapy in MPS I Dogs and Nonhuman Primates.

Published in:

Molecular Therapy, 2015, v. 23, n. 8, p. 1298, doi. 10.1038/mt.2015.99

By:

Hinderer, Christian;
Bell, Peter;
Louboutin, Jean-Pierre;
Zhu, Yanqing;
Yu, Hongwei;
Lin, Gloria;
Choa, Ruth;
Gurda, Brittney L;
Bagel, Jessica;
O'Donnell, Patricia;
Sikora, Tracey;
Ruane, Therese;
Wang, Ping;
Tarantal, Alice F;
Casal, Margret L;
Haskins, Mark E;
Wilson, James M

Publication type:

Article

High Local Concentrations of Intradermal MSCs Restore Skin Integrity and Facilitate Wound Healing in Dystrophic Epidermolysis Bullosa.

Published in:

Molecular Therapy, 2015, v. 23, n. 8, p. 1368, doi. 10.1038/mt.2015.58

By:

Kühl, Tobias;
Mezger, Markus;
Hausser, Ingrid;
Handgretinger, Rupert;
Bruckner-Tuderman, Leena;
Nyström, Alexander

Publication type:

Article

ASGCT and JSGT Joint Position Statement on Human Genomic Editing.

Published in:

Molecular Therapy, 2015, v. 23, n. 8, p. 1282, doi. 10.1038/mt.2015.118

By:

Friedmann, Theodore;
Jonlin, Erica C;
King, Nancy M P;
Torbett, Bruce E;
Wivel, Nelson A;
Kaneda, Yasufumi;
Sadelain, Michel

Publication type:

Article

From Mesoderm to Mesodermatology: Bone Marrow Mesenchymal Cells Heal Skin Wounds.

Published in:

Molecular Therapy, 2015, v. 23, n. 8, p. 1283, doi. 10.1038/mt.2015.84

By:

Tolarova, Marketa;
Tolar, Jakub

Publication type:

Article

Long-term Outcome of Extranodal NK/T Cell Lymphoma Patients Treated With Postremission Therapy Using EBV LMP1 and LMP2a-specific CTLs.

Published in:

Molecular Therapy, 2015, v. 23, n. 8, p. 1401, doi. 10.1038/mt.2015.91

By:

Cho, Seok-Goo;
Kim, Nayoun;
Sohn, Hyun-Jung;
Lee, Suk Kyeong;
Oh, Sang Taek;
Lee, Hyun-Joo;
Cho, Hyun-Il;
Yim, Hyeon Woo;
Jung, Seung Eun;
Park, Gyeongsin;
Oh, Joo Hyun;
Choi, Byung-Ock;
Kim, Sung Won;
Kim, Soo Whan;
Chung, Nak Gyun;
Lee, Jong Wook;
Hong, Young Seon;
Kim, Tai-Gyu

Publication type:

Article

Clinical Scale Zinc Finger Nuclease-mediated Gene Editing of PD-1 in Tumor Infiltrating Lymphocytes for the Treatment of Metastatic Melanoma.

Published in:

Molecular Therapy, 2015, v. 23, n. 8, p. 1380, doi. 10.1038/mt.2015.71

By:

Beane, Joal D;
Lee, Gary;
Zheng, Zhili;
Mendel, Matthew;
Abate-Daga, Daniel;
Bharathan, Mini;
Black, Mary;
Gandhi, Nimisha;
Yu, Zhiya;
Chandran, Smita;
Giedlin, Martin;
Ando, Dale;
Miller, Jeff;
Paschon, David;
Guschin, Dmitry;
Rebar, Edward J;
Reik, Andreas;
Holmes, Michael C;
Gregory, Philip D;
Restifo, Nicholas P

Publication type:

Article

HIV-specific Immunity Derived From Chimeric Antigen Receptor-engineered Stem Cells.

Published in:

Molecular Therapy, 2015, v. 23, n. 8, p. 1358, doi. 10.1038/mt.2015.102

By:

Zhen, Anjie;
Kamata, Masakazu;
Rezek, Valerie;
Rick, Jonathan;
Levin, Bernard;
Kasparian, Saro;
Chen, Irvin SY;
Yang, Otto O;
Zack, Jerome A;
Kitchen, Scott G

Publication type:

Article

Combination Antisense Treatment for Destructive Exon Skipping of Myostatin and Open Reading Frame Rescue of Dystrophin in Neonatal mdx Mice.

Published in:

Molecular Therapy, 2015, v. 23, n. 8, p. 1341, doi. 10.1038/mt.2015.88

By:

Lu-Nguyen, Ngoc B;
Jarmin, Susan A;
Saleh, Amer F;
Popplewell, Linda;
Gait, Michael J;
Dickson, George

Publication type:

Article

mRNA-transfected Dendritic Cells Expressing Polypeptides That Link MHC-I Presentation to Constitutive TLR4 Activation Confer Tumor Immunity.

Published in:

Molecular Therapy, 2015, v. 23, n. 8, p. 1391, doi. 10.1038/mt.2015.90

By:

Cafri, Gal;
Sharbi-Yunger, Adi;
Tzehoval, Esther;
Alteber, Zoya;
Gross, Tamar;
Vadai, Ezra;
Margalit, Alon;
Gross, Gideon;
Eisenbach, Lea

Publication type:

Article

Galectin-1 Protein Therapy Prevents Pathology and Improves Muscle Function in the mdx Mouse Model of Duchenne Muscular Dystrophy.

Published in:

Molecular Therapy, 2015, v. 23, n. 8, p. 1285, doi. 10.1038/mt.2015.105

By:

Van Ry, Pam M;
Wuebbles, Ryan D;
Key, Megan;
Burkin, Dean J

Publication type:

Article

Research Highlights.

Published in:: Molecular Therapy, 2015, v. 23, n. 8, p. 1281, doi. 10.1038/mt.2015.116
Publication type:: Article

S100A1 DNA-based Inotropic Therapy Protects Against Proarrhythmogenic Ryanodine Receptor 2 Dysfunction.

Published in:

Molecular Therapy, 2015, v. 23, n. 8, p. 1320, doi. 10.1038/mt.2015.93

By:

Ritterhoff, Julia;
Völkers, Mirko;
Seitz, Andreas;
Spaich, Kristin;
Gao, Erhe;
Peppel, Karsten;
Pleger, Sven T;
Zimmermann, Wolfram H;
Friedrich, Oliver;
Fink, Rainer H A;
Koch, Walter J;
Katus, Hugo A;
Most, Patrick

Publication type:

Article

Experimental Curative Fluorescence-guided Surgery of Highly Invasive Glioblastoma Multiforme Selectively Labeled With a Killer-reporter Adenovirus.

Published in:

Molecular Therapy, 2015, v. 23, n. 7, p. 1182, doi. 10.1038/mt.2015.63

By:

Yano, Shuya;
Miwa, Shinji;
Kishimoto, Hiroyuki;
Toneri, Makoto;
Hiroshima, Yukihiko;
Yamamoto, Mako;
Bouvet, Michael;
Urata, Yasuo;
Tazawa, Hiroshi;
Kagawa, Shunsuke;
Fujiwara, Toshiyoshi;
Hoffman, Robert M

Publication type:

Article