Works matching IS 15250016 AND DT 2014 AND VI 22 AND IP 1

Results: 29

Regenerating Cartilages by Engineered ASCs: Prolonged TGF-β3/BMP-6 Expression Improved Articular Cartilage Formation and Restored Zonal Structure.

Published in:

Molecular Therapy, 2014, v. 22, n. 1, p. 186, doi. 10.1038/mt.2013.165

By:

Lu, Chia-Hsin;
Yeh, Tsung-Szu;
Yeh, Chia-Lin;
Fang, Yu-Hua Dean;
Sung, Li-Yu;
Lin, Shih-Yeh;
Yen, Tzu-Chen;
Chang, Yu-Han;
Hu, Yu-Chen

Publication type:

Article

Immunogenic HSV-mediated Oncolysis Shapes the Antitumor Immune Response and Contributes to Therapeutic Efficacy.

Published in:

Molecular Therapy, 2014, v. 22, n. 1, p. 123, doi. 10.1038/mt.2013.238

By:

Workenhe, Samuel T;
Simmons, Graydon;
Pol, Jonathan G;
Lichty, Brian D;
Halford, William P;
Mossman, Karen L

Publication type:

Article

Platelet Gene Therapy by Lentiviral Gene Delivery to Hematopoietic Stem Cells Restores Hemostasis and Induces Humoral Immune Tolerance in FIXnull Mice.

Published in:

Molecular Therapy, 2014, v. 22, n. 1, p. 169, doi. 10.1038/mt.2013.197

By:

Chen, Yingyu;
Schroeder, Jocelyn A;
Kuether, Erin L;
Zhang, Guowei;
Shi, Qizhen

Publication type:

Article

Cardiac Progenitor Cells Engineered With βARKct Have Enhanced β-Adrenergic Tolerance.

Published in:

Molecular Therapy, 2014, v. 22, n. 1, p. 178, doi. 10.1038/mt.2013.200

By:

Khan, Mohsin;
Mohsin, Sadia;
Toko, Haruhiro;
Alkatib, Monique;
Nguyen, Jonathan;
Truffa, Silvia;
Gude, Natalie;
Chuprun, Kurt;
Tilley, Douglas G.;
Koch, Walter J.;
Sussman, Mark A.

Publication type:

Article

Research Highlights.

Published in:: Molecular Therapy, 2014, v. 22, n. 1, p. 5, doi. 10.1038/mt.2013.270
Publication type:: Article

Sindbis Viral Vectors Transiently Deliver Tumor-associated Antigens to Lymph Nodes and Elicit Diversified Antitumor CD8+ T-cell Immunity.

Published in:

Molecular Therapy, 2014, v. 22, n. 1, p. 112, doi. 10.1038/mt.2013.215

By:

Granot, Tomer;
Yamanashi, Yoshihide;
Meruelo, Daniel

Publication type:

Article

CD8+ T Cell Recognition of Epitopes Within the Capsid of Adeno-associated Virus 8-based Gene Transfer Vectors Depends on Vectors' Genome.

Published in:

Molecular Therapy, 2014, v. 22, n. 1, p. 42, doi. 10.1038/mt.2013.218

By:

Wu, Te-Lang;
Li, Hua;
Faust, Susan M;
Chi, Emily;
Zhou, Shangzhen;
Wright, Fraser;
High, Katherine A;
Ertl, Hildegund CJ

Publication type:

Article

AAV Empty Capsids: For Better or for Worse?

Published in:

Molecular Therapy, 2014, v. 22, n. 1, p. 1, doi. 10.1038/mt.2013.268

By:

Wright, J Fraser

Publication type:

Article

Combining Drugs and Biologics to Treat Nasopharyngeal Cancer.

Published in:

Molecular Therapy, 2014, v. 22, n. 1, p. 8, doi. 10.1038/mt.2013.272

By:

Heslop, Helen E

Publication type:

Article

AAV-mediated Liver-specific MPV17 Expression Restores mtDNA Levels and Prevents Diet-induced Liver Failure.

Published in:

Molecular Therapy, 2014, v. 22, n. 1, p. 10, doi. 10.1038/mt.2013.230

By:

Bottani, Emanuela;
Giordano, Carla;
Civiletto, Gabriele;
Di Meo, Ivano;
Auricchio, Alberto;
Ciusani, Emilio;
Marchet, Silvia;
Lamperti, Costanza;
d'Amati, Giulia;
Viscomi, Carlo;
Zeviani, Massimo

Publication type:

Article

Serial Transplantation and Long-term Engraftment of Intra-arterially Delivered Clonally Derived Mesenchymal Stem Cells to Injured Bone Marrow.

Published in:

Molecular Therapy, 2014, v. 22, n. 1, p. 160, doi. 10.1038/mt.2013.221

By:

Lin, Paul;
Correa, Diego;
Kean, Thomas J;
Awadallah, Amad;
Dennis, James E;
Caplan, Arnold I

Publication type:

Article

No Impact of Lentiviral Transduction on Hematopoietic Stem/Progenitor Cell Telomere Length or Gene Expression in the Rhesus Macaque Model.

Published in:

Molecular Therapy, 2014, v. 22, n. 1, p. 52, doi. 10.1038/mt.2013.168

By:

Sellers, Stephanie E;
Dumitriu, Bogdan;
Morgan, Mary J;
Hughes, William M.;
Wu, Colin O;
Raghavarchari, Nalini;
Yang, Yanqin;
Uchida, Naoya;
Tisdale, John F;
An, Dong S;
Chen, Irvin S;
Hematti, Peiman;
Donahue, Robert E;
LaRochelle, Andre;
Young, Neal S;
Calado, Rodrigo T;
Dunbar, Cynthia E

Publication type:

Article

T-cell Engager-armed Oncolytic Vaccinia Virus Significantly Enhances Antitumor Therapy.

Published in:

Molecular Therapy, 2014, v. 22, n. 1, p. 102, doi. 10.1038/mt.2013.240

By:

Yu, Feng;
Wang, Xingbing;
Guo, Z Sheng;
Bartlett, David L;
Gottschalk, Stephen M;
Song, Xiao-Tong

Publication type:

Article

Tissues in Different Anatomical Sites Can Sculpt and Vary the Tumor Microenvironment to Affect Responses to Therapy.

Published in:

Molecular Therapy, 2014, v. 22, n. 1, p. 18, doi. 10.1038/mt.2013.219

By:

Devaud, Christel;
Westwood, Jennifer A;
John, Liza B;
Flynn, Jacqueline K;
Paquet-Fifield, Sophie;
Duong, Connie PM;
Yong, Carmen SM;
Pegram, Hollie J;
Stacker, Steven A;
Achen, Marc G;
Stewart, Trina J;
Snyder, Linda A;
Teng, Michele WL;
Smyth, Mark J;
Darcy, Phillip K;
Kershaw, Michael H

Publication type:

Article

In Vitro and In Vivo Efficacy of SYL040012, a Novel siRNA Compound for Treatment of Glaucoma.

Published in:

Molecular Therapy, 2014, v. 22, n. 1, p. 81, doi. 10.1038/mt.2013.216

By:

Martínez, Tamara;
González, Maria Victoria;
Roehl, Ingo;
Wright, Natalia;
Pañeda, Covadonga;
Jiménez, Ana Isabel

Publication type:

Article

AAV8 Induces Tolerance in Murine Muscle as a Result of Poor APC Transduction, T Cell Exhaustion, and Minimal MHCI Upregulation on Target Cells.

Published in:

Molecular Therapy, 2014, v. 22, n. 1, p. 28, doi. 10.1038/mt.2013.134

By:

Mays, Lauren E;
Wang, Lili;
Lin, Jianping;
Bell, Peter;
Crawford, Alison;
Wherry, E John;
Wilson, James M

Publication type:

Article

Knockdown of β-catenin with Dicer-Substrate siRNAs Reduces Liver Tumor Burden In vivo.

Published in:

Molecular Therapy, 2014, v. 22, n. 1, p. 92, doi. 10.1038/mt.2013.233

By:

Dudek, Henryk;
Wong, Darren H;
Arvan, Rokhand;
Shah, Anee;
Wortham, Kathleen;
Ying, Bo;
Diwanji, Rohan;
Zhou, Wei;
Holmes, Benjamin;
Yang, Hailin;
Cyr, Wendy A;
Zhou, Yi;
Shah, Aalok;
Farkiwala, Ruchir;
Lee, Michael;
Li, Yiting;
Rettig, Garrett R;
Collingwood, Michael A;
Basu, Sujit K;
Behlke, Mark A

Publication type:

Article

In this issue.

Published in:: Molecular Therapy, 2014, v. 22, n. 1, p. 4, doi. 10.1038/mt.2013.269
Publication type:: Article

Genetic Vaccine for Respiratory Syncytial Virus Provides Protection Without Disease Potentiation.

Published in:

Molecular Therapy, 2014, v. 22, n. 1, p. 196, doi. 10.1038/mt.2013.142

By:

Johnson, Teresa R;
Rangel, David;
Graham, Barney S;
Brough, Douglas E;
Gall, Jason G

Publication type:

Article

Transduction of Fetal Mice With a Feline Lentiviral Vector Induces Liver Tumors Which Exhibit an E2F Activation Signature.

Published in:

Molecular Therapy, 2014, v. 22, n. 1, p. 59, doi. 10.1038/mt.2013.193

By:

Condiotti, Reba;
Goldenberg, Daniel;
Giladi, Hilla;
Schnitzer-Perlman, Temima;
Waddington, Simon N;
Buckley, Suzanne MK;
Heim, Denise;
Cheung, Wing;
Themis, Matthew;
Coutelle, Charles;
Simerzin, Alina;
Osejindu, Emma;
Wege, Henning;
Themis, Michael;
Galun, Eithan

Publication type:

Article

Targeting Intestinal Inflammation With CD98 siRNA/PEI-loaded Nanoparticles.

Published in:

Molecular Therapy, 2014, v. 22, n. 1, p. 69, doi. 10.1038/mt.2013.214

By:

Laroui, Hamed;
Geem, Duke;
Xiao, Bo;
Viennois, Emilie;
Rakhya, Poonam;
Denning, Timothy;
Merlin, Didier

Publication type:

Article

Coadministration of Seasonal Influenza Vaccine and MVA-NP+M1 Simultaneously Achieves Potent Humoral and Cell-Mediated Responses.

Published in:

Molecular Therapy, 2014, v. 22, n. 1, p. 233, doi. 10.1038/mt.2013.162

By:

Antrobus, Richard D;
Berthoud, Tamara K;
Mullarkey, Caitlin E;
Hoschler, Katja;
Coughlan, Lynda;
Zambon, Maria;
Hill, Adrian VS;
Gilbert, Sarah C

Publication type:

Article

Intranasal Delivery of Mesenchymal Stem Cells Significantly Extends Survival of Irradiated Mice with Experimental Brain Tumors.

Published in:

Molecular Therapy, 2014, v. 22, n. 1, p. 140, doi. 10.1038/mt.2013.199

By:

Balyasnikova, Irina V;
Prasol, Melanie S;
Ferguson, Sherise D;
Han, Yu;
Ahmed, Atique U;
Gutova, Margarita;
Tobias, Alex L;
Mustafi, Devkumar;
Rincón, Esther;
Zhang, Lingjiao;
Aboody, Karen S;
Lesniak, Maciej S

Publication type:

Article

Immunotherapy-induced CD8+ T Cells Instigate Immune Suppression in the Tumor.

Published in:

Molecular Therapy, 2014, v. 22, n. 1, p. 206, doi. 10.1038/mt.2013.255

By:

McGray, A J Robert;
Hallett, Robin;
Bernard, Dannie;
Swift, Stephanie L;
Zhu, Ziqiang;
Teoderascu, Florentina;
VanSeggelen, Heather;
Hassell, John A;
Hurwitz, Arthur A;
Wan, Yonghong;
Bramson, Jonathan L

Publication type:

Article

Phase I Clinical Trial of SYL040012, a Small Interfering RNA Targeting β-Adrenergic Receptor 2, for Lowering Intraocular Pressure.

Published in:

Molecular Therapy, 2014, v. 22, n. 1, p. 226, doi. 10.1038/mt.2013.217

By:

Moreno-Montañés, Javier;
Sádaba, Belén;
Ruz, Verónica;
Gómez-Guiu, Almudena;
Zarranz, Javier;
González, María Victoria;
Pañeda, Covadonga;
Jimenez, Ana Isabel

Publication type:

Article

Autologous Myoblast Transplantation for Oculopharyngeal Muscular Dystrophy: a Phase I/Iia Clinical Study.

Published in:

Molecular Therapy, 2014, v. 22, n. 1, p. 219, doi. 10.1038/mt.2013.155

By:

Périé, Sophie;
Trollet, Capucine;
Mouly, Vincent;
Vanneaux, Valérie;
Mamchaoui, Kamel;
Bouazza, Belaïd;
Marolleau, Jean Pierre;
Laforêt, Pascal;
Chapon, Françoise;
Eymard, Bruno;
Butler-Browne, Gillian;
Larghero, Jérome;
St Guily, Jean Lacau

Publication type:

Article

Exploiting Human CD34+ Stem Cell-conditioned Medium for Tissue Repair.

Published in:

Molecular Therapy, 2014, v. 22, n. 1, p. 149, doi. 10.1038/mt.2013.194

By:

Mintz, Paul J;
Huang, Kai-Wen;
Reebye, Vikash;
Nteliopoulos, Georgios;
Lai, Hong-Shiee;
Sætrom, Pal;
Kasahara, Noriyuki;
Jensen, Steen;
Pai, Madhava;
Gordon, Myrtle YA;
Marley, Stephen B;
Behan, Rosemary;
Spalding, Duncan R;
Haoudi, Abdelali;
Emara, Mohamed M;
Nicholls, Joanna;
Rossi, John J;
Habib, Nagy A

Publication type:

Article

Giving Oncolytic Vaccinia Virus More BiTE.

Published in:

Molecular Therapy, 2014, v. 22, n. 1, p. 6, doi. 10.1038/mt.2013.271

By:

Albelda, Steven M;
Thorne, Steve H

Publication type:

Article

Adoptive T-cell Transfer and Chemotherapy in the First-line Treatment of Metastatic and/or Locally Recurrent Nasopharyngeal Carcinoma.

Published in:

Molecular Therapy, 2014, v. 22, n. 1, p. 132, doi. 10.1038/mt.2013.242

By:

Chia, Whay-Kuang;
Teo, Marissa;
Wang, Who-Whong;
Lee, Bernett;
Ang, Soo-Fan;
Tai, Wai-Meng;
Chee, Chit-Lai;
Ng, Joanna;
Kan, Rebecca;
Lim, Wan-Teck;
Tan, Sze-Huey;
Ong, Whee-Sze;
Cheung, Yin-Bun;
Tan, Eng-Huat;
Connolly, John E;
Gottschalk, Stephen;
Toh, Han-Chong

Publication type:

Article

Works matching IS 15250016 AND DT 2014 AND VI 22 AND IP 1

Regenerating Cartilages by Engineered ASCs: Prolonged TGF-β3/BMP-6 Expression Improved Articular Cartilage Formation and Restored Zonal Structure.

Immunogenic HSV-mediated Oncolysis Shapes the Antitumor Immune Response and Contributes to Therapeutic Efficacy.

Platelet Gene Therapy by Lentiviral Gene Delivery to Hematopoietic Stem Cells Restores Hemostasis and Induces Humoral Immune Tolerance in FIX<sup>null</sup> Mice.

Cardiac Progenitor Cells Engineered With βARKct Have Enhanced β-Adrenergic Tolerance.

Research Highlights.

Sindbis Viral Vectors Transiently Deliver Tumor-associated Antigens to Lymph Nodes and Elicit Diversified Antitumor CD8<sup>+</sup> T-cell Immunity.

CD8<sup>+</sup> T Cell Recognition of Epitopes Within the Capsid of Adeno-associated Virus 8-based Gene Transfer Vectors Depends on Vectors' Genome.

AAV Empty Capsids: For Better or for Worse?

Combining Drugs and Biologics to Treat Nasopharyngeal Cancer.

AAV-mediated Liver-specific MPV17 Expression Restores mtDNA Levels and Prevents Diet-induced Liver Failure.

Serial Transplantation and Long-term Engraftment of Intra-arterially Delivered Clonally Derived Mesenchymal Stem Cells to Injured Bone Marrow.

No Impact of Lentiviral Transduction on Hematopoietic Stem/Progenitor Cell Telomere Length or Gene Expression in the Rhesus Macaque Model.

T-cell Engager-armed Oncolytic Vaccinia Virus Significantly Enhances Antitumor Therapy.

Tissues in Different Anatomical Sites Can Sculpt and Vary the Tumor Microenvironment to Affect Responses to Therapy.

In Vitro and In Vivo Efficacy of SYL040012, a Novel siRNA Compound for Treatment of Glaucoma.

AAV8 Induces Tolerance in Murine Muscle as a Result of Poor APC Transduction, T Cell Exhaustion, and Minimal MHCI Upregulation on Target Cells.

Knockdown of β-catenin with Dicer-Substrate siRNAs Reduces Liver Tumor Burden In vivo.

In this issue.

Genetic Vaccine for Respiratory Syncytial Virus Provides Protection Without Disease Potentiation.

Transduction of Fetal Mice With a Feline Lentiviral Vector Induces Liver Tumors Which Exhibit an E2F Activation Signature.

Targeting Intestinal Inflammation With CD98 siRNA/PEI-loaded Nanoparticles.

Coadministration of Seasonal Influenza Vaccine and MVA-NP+M1 Simultaneously Achieves Potent Humoral and Cell-Mediated Responses.

Intranasal Delivery of Mesenchymal Stem Cells Significantly Extends Survival of Irradiated Mice with Experimental Brain Tumors.

Immunotherapy-induced CD8<sup>+</sup> T Cells Instigate Immune Suppression in the Tumor.

Phase I Clinical Trial of SYL040012, a Small Interfering RNA Targeting β-Adrenergic Receptor 2, for Lowering Intraocular Pressure.

Autologous Myoblast Transplantation for Oculopharyngeal Muscular Dystrophy: a Phase I/Iia Clinical Study.

Exploiting Human CD34<sup>+</sup> Stem Cell-conditioned Medium for Tissue Repair.

Giving Oncolytic Vaccinia Virus More BiTE.

Adoptive T-cell Transfer and Chemotherapy in the First-line Treatment of Metastatic and/or Locally Recurrent Nasopharyngeal Carcinoma.